IMP
Process View
chronic inflammatory response
Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "chronic inflammatory response"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Tnf | tumor necrosis factor | 1.000 | ||
| Ifng | interferon gamma | 0.991 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.953 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.894 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.771 | Zebrafish | |
| Lyz2 | lysozyme 2 | 0.764 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.763 | ||
| Il4 | interleukin 4 | 0.699 | ||
| Lta | lymphotoxin A | 0.628 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.499 | ||
| Cd19 | CD19 antigen | 0.370 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.324 | ||
| Igh | immunoglobulin heavy chain complex | 0.308 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.278 | ||
| Tlr4 | toll-like receptor 4 | 0.245 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.241 | ||
| Il2 | interleukin 2 | 0.237 | ||
| Rag1 | recombination activating gene 1 | 0.225 | ||
| Vdr | vitamin D receptor | 0.208 | ||
| Il6 | interleukin 6 | 0.200 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.197 | ||
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.187 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.175 | ||
| Tox | thymocyte selection-associated high mobility group box | 0.175 | ||
| Tcra | T-cell receptor alpha chain | 0.158 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.152 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.144 | ||
| Ltb | lymphotoxin B | 0.128 | ||
| Il1b | interleukin 1 beta | 0.103 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.101 | ||
| Cd40 | CD40 antigen | 0.089 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.088 | ||
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.086 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.080 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.078 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.069 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.067 | ||
| Mb | myoglobin | 0.065 | ||
| Il10 | interleukin 10 | 0.060 | ||
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.049 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.039 | ||
| Irg1 | immunoresponsive gene 1 | 0.037 | ||
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.034 | Mouse | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.034 | ||
| Cd44 | CD44 antigen | 0.032 | ||
| Il7 | interleukin 7 | 0.032 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.031 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.030 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.029 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.027 | ||
| 1100001G20Rik | RIKEN cDNA 1100001G20 gene | 0.027 | ||
| Clec4d | C-type lectin domain family 4, member d | 0.026 | ||
| Selp | selectin, platelet | 0.025 | ||
| Trp53 | transformation related protein 53 | 0.024 | ||
| Fpr2 | formyl peptide receptor 2 | 0.024 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.024 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.022 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.018 | ||
| Clec4e | C-type lectin domain family 4, member e | 0.018 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.018 | ||
| Foxp1 | forkhead box P1 | 0.017 | Mouse | |
| Il1a | interleukin 1 alpha | 0.017 | ||
| Spp1 | secreted phosphoprotein 1 | 0.017 | ||
| Apoe | apolipoprotein E | 0.016 | ||
| Cxcl5 | chemokine (C-X-C motif) ligand 5 | 0.016 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.015 | ||
| Id2 | inhibitor of DNA binding 2 | 0.015 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.015 | ||
| Lcn2 | lipocalin 2 | 0.015 | ||
| Tlr2 | toll-like receptor 2 | 0.015 | ||
| Gzmb | granzyme B | 0.015 | ||
| Ldlr | low density lipoprotein receptor | 0.015 | ||
| Tcf3 | transcription factor 3 | 0.014 | ||
| Cd28 | CD28 antigen | 0.013 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.013 | ||
| Plaur | plasminogen activator, urokinase receptor | 0.013 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.012 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.012 | ||
| Saa3 | serum amyloid A 3 | 0.012 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.012 | ||
| Irf1 | interferon regulatory factor 1 | 0.012 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.012 | ||
| Ikbkg | inhibitor of kappaB kinase gamma | 0.012 | ||
| Ubd | ubiquitin D | 0.011 | ||
| Foxp3 | forkhead box P3 | 0.011 | ||
| Rag2 | recombination activating gene 2 | 0.011 | ||
| Pdcd1 | programmed cell death 1 | 0.011 | ||
| Chi3l3 | chitinase 3-like 3 | 0.011 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.010 | ||
| Foxn1 | forkhead box N1 | 0.010 |