IMP

Process View

Mus musculus

17 genes annotated in mouse

bile acid metabolic process

The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "bile acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bile acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.797
Rxra	retinoid X receptor alpha	0.525
Pax2	paired box gene 2	0.516
Rarg	retinoic acid receptor, gamma	0.371	Mouse
Sox9	SRY-box containing gene 9	0.315
Esr1	estrogen receptor 1 (alpha)	0.306
Rara	retinoic acid receptor, alpha	0.299	Mouse
Kl	klotho	0.282
Irs2	insulin receptor substrate 2	0.162
Ghr	growth hormone receptor	0.159
Casr	calcium-sensing receptor	0.136
Ar	androgen receptor	0.134
Pparg	peroxisome proliferator activated receptor gamma	0.132	Mouse
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.128
Cav1	caveolin 1, caveolae protein	0.117
Prlr	prolactin receptor	0.107
Fgfr1	fibroblast growth factor receptor 1	0.094	Mouse
Pten	phosphatase and tensin homolog	0.094
Pax8	paired box gene 8	0.094
Insr	insulin receptor	0.080
Fgfr3	fibroblast growth factor receptor 3	0.072	Mouse
Pnpla2	patatin-like phospholipase domain containing 2	0.067
Bmp4	bone morphogenetic protein 4	0.067
Kiss1	KiSS-1 metastasis-suppressor	0.066
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.060
Vdr	vitamin D receptor	0.060	Mouse
Thra	thyroid hormone receptor alpha	0.054	Mouse
Otc	ornithine transcarbamylase	0.044
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.043
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.042
Wnt9b	wingless-type MMTV integration site 9B	0.039
Emx2	empty spiracles homolog 2 (Drosophila)	0.038
Dio1	deiodinase, iodothyronine, type I	0.038
Apoe	apolipoprotein E	0.037
F13b	coagulation factor XIII, beta subunit	0.037
Fgfr2	fibroblast growth factor receptor 2	0.037	Mouse
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.037
Rarb	retinoic acid receptor, beta	0.035	Mouse
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.034
Fgf8	fibroblast growth factor 8	0.034
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.029
Tef	thyrotroph embryonic factor	0.029
Rxrg	retinoid X receptor gamma	0.029
Plin1	perilipin 1	0.028
Hgd	homogentisate 1, 2-dioxygenase	0.027
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.027
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.027
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.027	Mouse
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.026	Mouse
Bmp7	bone morphogenetic protein 7	0.026
Apob	apolipoprotein B	0.025
Plin4	perilipin 4	0.025
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.025
Fmo4	flavin containing monooxygenase 4	0.025
Dbp	D site albumin promoter binding protein	0.024
Nf1	neurofibromatosis 1	0.024
Hes1	hairy and enhancer of split 1 (Drosophila)	0.024
Gata6	GATA binding protein 6	0.023
Ece1	endothelin converting enzyme 1	0.023
Gata4	GATA binding protein 4	0.023
Mecp2	methyl CpG binding protein 2	0.023
Pkd1	polycystic kidney disease 1 homolog	0.023
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.022
Ednra	endothelin receptor type A	0.022
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.022
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.022
Thrb	thyroid hormone receptor beta	0.021	Mouse
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.021	Mouse
Agmat	agmatine ureohydrolase (agmatinase)	0.021
Sox4	SRY-box containing gene 4	0.021
Tert	telomerase reverse transcriptase	0.021
Lhx1	LIM homeobox protein 1	0.021
Cps1	carbamoyl-phosphate synthetase 1	0.021
Trp53	transformation related protein 53	0.020
Chrna2	cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)	0.020
Acot1	acyl-CoA thioesterase 1	0.020	Mouse
Hnf4a	hepatic nuclear factor 4, alpha	0.020
Acvr1	activin A receptor, type 1	0.020
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.020
Inhbe	inhibin beta E	0.020
Vegfa	vascular endothelial growth factor A	0.020
Acot2	acyl-CoA thioesterase 2	0.019	Mouse
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.019	Mouse
1810021B22Rik	RIKEN cDNA 1810021B22 gene	0.019
Duox2	dual oxidase 2	0.019
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.019
Rdh16	retinol dehydrogenase 16	0.019
Hao2	hydroxyacid oxidase 2	0.019
G6pc	glucose-6-phosphatase, catalytic	0.018
Slc34a3	solute carrier family 34 (sodium phosphate), member 3	0.018
Gna11	guanine nucleotide binding protein, alpha 11	0.018
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.018
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.018
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.018
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.018	Human Mouse Rat
Ppara	peroxisome proliferator activated receptor alpha	0.017	Mouse
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.017
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.017
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.016
Aadat	aminoadipate aminotransferase	0.016
Slc26a5	solute carrier family 26, member 5	0.015
Igf1	insulin-like growth factor 1	0.015
Iyd	iodotyrosine deiodinase	0.015
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.015
Prdm16	PR domain containing 16	0.015
Keg1	kidney expressed gene 1	0.015
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.015
Acot12	acyl-CoA thioesterase 12	0.014
Braf	Braf transforming gene	0.014
Mpv17	MpV17 mitochondrial inner membrane protein	0.014
Fgfrl1	fibroblast growth factor receptor-like 1	0.014
Pzp	pregnancy zone protein	0.014
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.014
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.014
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.014
Lrp1	low density lipoprotein receptor-related protein 1	0.013
Idua	iduronidase, alpha-L-	0.013
Fam20c	family with sequence similarity 20, member C	0.013
Lpin1	lipin 1	0.013
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.013
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.013
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.013
Tgfbr2	transforming growth factor, beta receptor II	0.013
Afm	afamin	0.013
Cfhr1	complement factor H-related 1	0.012
Nos3	nitric oxide synthase 3, endothelial cell	0.012
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.012
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.012
Ncoa1	nuclear receptor coactivator 1	0.012
Nr1d2	nuclear receptor subfamily 1, group D, member 2	0.012	Mouse
Acot3	acyl-CoA thioesterase 3	0.012	Mouse
Aldob	aldolase B, fructose-bisphosphate	0.012
Azgp1	alpha-2-glycoprotein 1, zinc	0.012
Ncoa3	nuclear receptor coactivator 3	0.012
Egfr	epidermal growth factor receptor	0.012
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.012
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.012
Cidec	cell death-inducing DFFA-like effector c	0.012
Mixl1	Mix1 homeobox-like 1 (Xenopus laevis)	0.012
Agxt2	alanine-glyoxylate aminotransferase 2	0.012
Treh	trehalase (brush-border membrane glycoprotein)	0.012
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.012
Allc	allantoicase	0.012
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.011
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.011
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.011
Vhl	von Hippel-Lindau tumor suppressor	0.011
Akr1c21	aldo-keto reductase family 1, member C21	0.011	Human
Mup5	major urinary protein 5	0.011
Foxo3	forkhead box O3	0.011
Asgr2	asialoglycoprotein receptor 2	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Hrg	histidine-rich glycoprotein	0.011
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.011
Apoh	apolipoprotein H	0.011
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.011
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.011
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.011
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.011
1110002B05Rik	RIKEN cDNA 1110002B05 gene	0.011
Nfic	nuclear factor I/C	0.011
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.011
Fshr	follicle stimulating hormone receptor	0.011
Glyat	glycine-N-acyltransferase	0.011
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.011
Nr1d1	nuclear receptor subfamily 1, group D, member 1	0.010
D630002G06Rik	RIKEN cDNA D630002G06 gene	0.010
Ybx2	Y box protein 2	0.010
Foxo4	forkhead box O4	0.010
Mbl1	mannose-binding lectin (protein A) 1	0.010
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.010
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.010
Lamc1	laminin, gamma 1	0.010
Bmper	BMP-binding endothelial regulator	0.010
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.010
Lep	leptin	0.010
Ager	advanced glycosylation end product-specific receptor	0.010
BC089597	cDNA sequence BC089597	0.010
Npc1	Niemann Pick type C1	0.010
Ces1g	carboxylesterase 1G	0.010