The network for 'photoreceptor cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

photoreceptor cell differentiation

The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.

Drosophila melanogaster
Name Description Probability Func Analog Organism
N Notch 1.000
S6kII RPS6-protein kinase-II 0.997
Moe Moesin 0.997
ed echinoid 0.995
csw corkscrew 0.994
sev sevenless 0.993
ttk tramtrack 0.992
hyd hyperplastic discs 0.990
Rac1 CG2248 gene product from transcript CG2248-RA 0.984
HLHm7 E(spl) region transcript m7 0.979
phl pole hole 0.976
Gug Grunge 0.975
ebi CG4063 gene product from transcript CG4063-RA 0.974
eyg eyegone 0.971
Fas2 Fasciclin 2 0.970
Nrt Neurotactin 0.969
sty sprouty 0.967
phyl phyllopod 0.953
InR Insulin-like receptor 0.949
arm armadillo 0.946
bs blistered 0.945
crb crumbs 0.941
argos CG4531 gene product from transcript CG4531-RA 0.940
E(spl) Enhancer of split 0.932
dsh dishevelled 0.931
rdgA retinal degeneration A 0.927
trx trithorax 0.924
dac dachshund 0.911
Lis-1 Lissencephaly-1 0.910
ato atonal 0.910
Gap1 GTPase-activating protein 1 0.891
hdc headcase 0.889
esg escargot 0.886
Rala Ras-related protein 0.881
usp ultraspiracle 0.880
Rme-8 Receptor mediated endocytosis 8 0.874
Ubx Ultrabithorax 0.873
Akt1 CG4006 gene product from transcript CG4006-RA 0.865
hep hemipterous 0.865
wdb widerborst 0.862
amos absent MD neurons and olfactory sensilla 0.857
Jra Jun-related antigen 0.847
Dsor1 Downstream of raf1 0.845
Pp2B-14D Protein phosphatase 2B at 14D 0.842
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.839
Taf6 TBP-associated factor 6 0.837
Vang Van Gogh 0.829
shg shotgun 0.827
rg rugose 0.827
cdi center divider 0.825
ct cut 0.813
trio CG18214 gene product from transcript CG18214-RA 0.809
sens senseless 0.806
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.803
Egfr Epidermal growth factor receptor 0.800
unk unkempt 0.799
kay kayak 0.798
pie pineapple eye 0.797
Ser Serrate 0.797
boss bride of sevenless 0.768
RASSF8 CG5053 gene product from transcript CG5053-RA 0.760
RhoGAP100F CG1976 gene product from transcript CG1976-RB 0.759
Ten-m Tenascin major 0.758
tkv thickveins 0.757
dco discs overgrown 0.752
eys eyes shut 0.749
rok Rho-kinase 0.745
sktl skittles 0.737
klu klumpfuss 0.734
Dsp1 Dorsal switch protein 1 0.733
trpl trp-like 0.730
Hop Hsp70/Hsp90 organizing protein homolog 0.717
HLHmbeta E(spl) region transcript mbeta 0.710
nmo nemo 0.707
Dl Delta 0.703
R Roughened 0.703
eya eyes absent 0.686
HLHmdelta E(spl) region transcript mdelta 0.685
trp transient receptor potential 0.675
Mob2 CG11711 gene product from transcript CG11711-RC 0.673
dpp decapentaplegic 0.671
disco disconnected 0.667
bif bifocal 0.664
vvl ventral veins lacking 0.662
dsx doublesex 0.659
spen split ends 0.653
Apc APC-like 0.647
chp chaoptic 0.646
hbs hibris 0.644
Atx2 Ataxin-2 0.634
Mrtf Myocardin-related transcription factor 0.634
TER94 CG2331 gene product from transcript CG2331-RA 0.632
Arr1 Arrestin 1 0.623
rin rasputin 0.622
Gef26 CG9491 gene product from transcript CG9491-RB 0.618
wg wingless 0.617
chic chickadee 0.617
Pten CG5671 gene product from transcript CG5671-RB 0.603
Hr51 Hormone receptor 51 0.595
CtBP C-terminal Binding Protein 0.587
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
neurod neurogenic differentiation 0.997
kif17 kinesin family member 17 0.996
cdh2 cadherin 2, neuronal 0.996
shha sonic hedgehog a 0.993
foxi1 forkhead box I1 0.992
tfap2a transcription factor AP-2 alpha 0.988
ift88 intraflagellar transport 88 homolog 0.988
otx2 orthodenticle homolog 2 0.986
jag2 jagged 2 0.984
pax2a paired box gene 2a 0.981
bmp4 bone morphogenetic protein 4 0.979
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.975
bmp2b bone morphogenetic protein 2b 0.967
sox2 SRY-box containing gene 2 0.967
flh floating head 0.962
ptf1a pancreas specific transcription factor, 1a 0.939
ahi1 Abelson helper integration site 1 0.932
neurog1 neurogenin 1 0.884
crx cone-rod homeobox 0.884
hnf1ba HNF1 homeobox Ba 0.872
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.847
crb2a crumbs homolog 2a 0.834
pax6b paired box gene 6b 0.830
foxa2 forkhead box A2 0.828
rx2 retinal homeobox gene 2 0.822
six3a sine oculis homeobox homolog 3a 0.810
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.809
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.800
otx1b orthodenticle homolog 1b 0.785
cdon cell adhesion molecule-related/down-regulated by oncogenes 0.780
zgc:162213 zgc:162213 0.763
lrrc6 leucine rich repeat containing 6 0.752
irx7 iroquois homeobox protein 7 0.748
sox9a SRY-box containing gene 9a 0.656
gbx2 gastrulation brain homeo box 2 0.648
tbx2b T-box 2b 0.637
fezf2 FEZ family zinc finger 2 0.630
cdh1 cadherin 1, epithelial 0.623
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.601
pdzd7a PDZ domain containing 7a 0.586
cc2d2a coiled-coil and C2 domain containing 2A 0.582
isl1 islet1 0.565
dla deltaA 0.558
gucy2f guanylate cyclase 2F, retinal 0.557
guca1c guanylate cyclase activator 1C 0.554
her1 hairy-related 1 0.550
rorcb RAR-related orphan receptor C b 0.524
clrn1 clarin 1 0.507
dlx3b distal-less homeobox gene 3b 0.497
irx4b iroquois homeobox protein 4b 0.496
ctbp2 C-terminal binding protein 2 0.471
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.457
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.444
rx1 retinal homeobox gene 1 0.441
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.435
ahctf1 AT hook containing transcription factor 1 0.419
otx5 orthodenticle homolog 5 0.401
jag1b jagged 1b 0.399
tp53 tumor protein p53 0.394
ift172 intraflagellar transport 172 0.382
tbx5a T-box 5a 0.378
dctn1a dynactin 1a 0.365
wt1b wilms tumor 1b 0.358
irx1b iroquois homeobox protein 1, b 0.357
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.352
gli1 GLI-Kruppel family member 1 0.337
neo1 neogenin 1 0.331
sox4a SRY-box containing gene 4a 0.329
pcdh17 protocadherin 17 0.329
zgc:100838 zgc:100838 0.323
olfm1b olfactomedin 1b 0.319
bmper BMP binding endothelial regulator 0.311
wtip Wilms tumor 1 interacting protein 0.309
stil TAL1 (SCL) interrupting locus 0.304
pcdh8 protocadherin 8 0.302
fgf8a fibroblast growth factor 8 a 0.287
raraa retinoic acid receptor, alpha a 0.287
foxa3 forkhead box A3 0.285
six3b sine oculis homeobox homolog 3b 0.284
cadm3 cell adhesion molecule 3 0.276
her6 hairy-related 6 0.268
notch1a notch homolog 1a 0.267
vsx2 visual system homeobox 2 0.265
gc3 guanylyl cyclase 3 0.265
emx3 empty spiracles homeobox 3 0.262
ocrl oculocerebrorenal syndrome of Lowe 0.261
foxd5 forkhead box D5 0.258
prox1 prospero-related homeobox gene 1 0.257
gpr98 G protein-coupled receptor 98 0.252
lft1 lefty1 0.250
olig2 oligodendrocyte lineage transcription factor 2 0.249
foxp2 forkhead box P2 0.247
msgn1 mesogenin 1 0.244
sall1a sal-like 1a (Drosophila) 0.243
otpb orthopedia homolog b 0.239
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.238
atoh7 atonal homolog 7 0.237
sncb synuclein, beta 0.236
nkx2.1a NK2 homeobox 1a 0.235
notch2 notch homolog 2 0.225
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Homo sapiens
Name Description Probability Func Analog Organism
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.997
MAP2K1 mitogen-activated protein kinase kinase 1 0.986
EGFR epidermal growth factor receptor 0.982
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.979
MAPK1 mitogen-activated protein kinase 1 0.967
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.962
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.936
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.935
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.915
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.909
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.866
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.851
GBP3 guanylate binding protein 3 0.818
PTPRJ protein tyrosine phosphatase, receptor type, J 0.805
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.784
NCOR1 nuclear receptor corepressor 1 0.766
PDE4DIP phosphodiesterase 4D interacting protein 0.766
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.748
CAV1 caveolin 1, caveolae protein, 22kDa 0.718
IGF1R insulin-like growth factor 1 receptor 0.690
APC adenomatous polyposis coli 0.681
C2orf65 chromosome 2 open reading frame 65 0.672
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.639
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.632
HDAC3 histone deacetylase 3 0.560
BBS9 Bardet-Biedl syndrome 9 0.532
UNC119 unc-119 homolog (C. elegans) 0.528
DYNLT3 dynein, light chain, Tctex-type 3 0.521
BBS2 Bardet-Biedl syndrome 2 0.517
IRS1 insulin receptor substrate 1 0.517
GSK3B glycogen synthase kinase 3 beta 0.515
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.492
MED10 mediator complex subunit 10 0.478
MED20 mediator complex subunit 20 0.468
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.467
HDAC4 histone deacetylase 4 0.444
ZNF746 zinc finger protein 746 0.439
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.420
NRP1 neuropilin 1 0.405
NOTCH3 notch 3 0.403
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.395
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.391
SOS1 son of sevenless homolog 1 (Drosophila) 0.382
PRKCE protein kinase C, epsilon 0.373
GAB2 GRB2-associated binding protein 2 0.371
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.329
EZR ezrin 0.300
CDH5 cadherin 5, type 2 (vascular endothelium) 0.298
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.295
MED29 mediator complex subunit 29 0.295
BBS1 Bardet-Biedl syndrome 1 0.289
DUSP3 dual specificity phosphatase 3 0.288
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.288
JAM2 junctional adhesion molecule 2 0.283
MDFI MyoD family inhibitor 0.281
GRB2 growth factor receptor-bound protein 2 0.279
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.270
PGF placental growth factor 0.261
MAML1 mastermind-like 1 (Drosophila) 0.248
CADM4 cell adhesion molecule 4 0.245
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.240
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.236
ATXN1 ataxin 1 0.235
GAB1 GRB2-associated binding protein 1 0.230
RAP1GAP RAP1 GTPase activating protein 0.225
CTNNBIP1 catenin, beta interacting protein 1 0.225
TFRC transferrin receptor (p90, CD71) 0.224
PRKCA protein kinase C, alpha 0.223
TSC2 tuberous sclerosis 2 0.217
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.216
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.216
LMO4 LIM domain only 4 0.215
PCM1 pericentriolar material 1 0.214
CAV2 caveolin 2 0.214
GADD45G growth arrest and DNA-damage-inducible, gamma 0.211
MPP1 membrane protein, palmitoylated 1, 55kDa 0.202
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.201
ZNF512B zinc finger protein 512B 0.198
INSR insulin receptor 0.197
MAPK3 mitogen-activated protein kinase 3 0.197
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.194
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.192
NKX2-1 NK2 homeobox 1 0.182
MED12 mediator complex subunit 12 0.182
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.175
JAG1 jagged 1 0.175
BBS4 Bardet-Biedl syndrome 4 0.175
MAPK14 mitogen-activated protein kinase 14 0.174
TCF4 transcription factor 4 0.173
MCC mutated in colorectal cancers 0.169
DUSP1 dual specificity phosphatase 1 0.167
PIAS1 protein inhibitor of activated STAT, 1 0.166
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.161
WEE1 WEE1 homolog (S. pombe) 0.161
NTF4 neurotrophin 4 0.159
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.156
ZFYVE9 zinc finger, FYVE domain containing 9 0.155
TAL1 T-cell acute lymphocytic leukemia 1 0.154
SRI sorcin 0.150
MED16 mediator complex subunit 16 0.150
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.999
Pax6 paired box gene 6 0.999
Pten phosphatase and tensin homolog 0.993
Otx2 orthodenticle homolog 2 (Drosophila) 0.991
Sox2 SRY-box containing gene 2 0.987
Pax2 paired box gene 2 0.978
Emx1 empty spiracles homolog 1 (Drosophila) 0.974
Atoh7 atonal homolog 7 (Drosophila) 0.963
Crb2 crumbs homolog 2 (Drosophila) 0.946
Rho rhodopsin 0.944
Gli3 GLI-Kruppel family member GLI3 0.941
Dcx doublecortin 0.894
Fgfr1 fibroblast growth factor receptor 1 0.887
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.842
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.832
Notch2 Notch gene homolog 2 (Drosophila) 0.822
Id3 inhibitor of DNA binding 3 0.807
Bbs2 Bardet-Biedl syndrome 2 (human) 0.785
Pou4f2 POU domain, class 4, transcription factor 2 0.782
Ctnnb1 catenin (cadherin associated protein), beta 1 0.781
Isl1 ISL1 transcription factor, LIM/homeodomain 0.766
Kit kit oncogene 0.759
Pax3 paired box gene 3 0.740
Fgfr2 fibroblast growth factor receptor 2 0.735
Hes1 hairy and enhancer of split 1 (Drosophila) 0.716
Notch1 Notch gene homolog 1 (Drosophila) 0.672
Arl6 ADP-ribosylation factor-like 6 0.643
Id1 inhibitor of DNA binding 1 0.634
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.623
Psen1 presenilin 1 0.619
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.618
Stat5b signal transducer and activator of transcription 5B 0.613
Pkd1 polycystic kidney disease 1 homolog 0.604
Thra thyroid hormone receptor alpha 0.596
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.594
Chd7 chromodomain helicase DNA binding protein 7 0.556
Iqcb1 IQ calmodulin-binding motif containing 1 0.555
Ift88 intraflagellar transport 88 homolog (Chlamydomonas) 0.528
Nf1 neurofibromatosis 1 0.521
Emx2 empty spiracles homolog 2 (Drosophila) 0.509
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.502
Stat5a signal transducer and activator of transcription 5A 0.489
Crx cone-rod homeobox containing gene 0.474
Foxc1 forkhead box C1 0.467
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.439
Grb10 growth factor receptor bound protein 10 0.437
Tcfap2a transcription factor AP-2, alpha 0.420
Cbln1 cerebellin 1 precursor protein 0.413
Ret ret proto-oncogene 0.405
Cbl Casitas B-lineage lymphoma 0.401
Igh immunoglobulin heavy chain complex 0.395
Nos1 nitric oxide synthase 1, neuronal 0.390
Neurod1 neurogenic differentiation 1 0.381
Irf9 interferon regulatory factor 9 0.377
Tbx3 T-box 3 0.368
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.352
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.351
Atxn1 ataxin 1 0.343
Gata3 GATA binding protein 3 0.338
Neurog2 neurogenin 2 0.334
Kif3a kinesin family member 3A 0.332
Adra2b adrenergic receptor, alpha 2b 0.327
Dlx5 distal-less homeobox 5 0.319
Nos3 nitric oxide synthase 3, endothelial cell 0.318
Prph2 peripherin 2 0.317
Rxra retinoid X receptor alpha 0.313
Fgf8 fibroblast growth factor 8 0.312
Raf1 v-raf-leukemia viral oncogene 1 0.311
Mapk3 mitogen-activated protein kinase 3 0.301
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.301
Lhx1 LIM homeobox protein 1 0.295
Myo6 myosin VI 0.290
Cacna1f calcium channel, voltage-dependent, alpha 1F subunit 0.286
Trp73 transformation related protein 73 0.284
Shc1 src homology 2 domain-containing transforming protein C1 0.283
Dnmt3a DNA methyltransferase 3A 0.282
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 0.281
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.274
Vhl von Hippel-Lindau tumor suppressor 0.273
Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.272
En2 engrailed 2 0.271
Rgl2 ral guanine nucleotide dissociation stimulator-like 2 0.270
Dll1 delta-like 1 (Drosophila) 0.270
Reln reelin 0.269
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.263
Jup junction plakoglobin 0.263
Dctn1 dynactin 1 0.261
Tyr tyrosinase 0.261
Prox1 prospero-related homeobox 1 0.253
Rbp3 retinol binding protein 3, interstitial 0.252
Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3 0.251
Cd2ap CD2-associated protein 0.250
Wnt9b wingless-type MMTV integration site 9B 0.247
Rb1 retinoblastoma 1 0.243
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.239
Ar androgen receptor 0.238
Stat3 signal transducer and activator of transcription 3 0.237
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.237
Grb2 growth factor receptor bound protein 2 0.230
Bcl2 B-cell leukemia/lymphoma 2 0.230
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism