IMP
Process View
The network for 'cd4 positive alpha beta t cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cd4 positive alpha beta t cell differentiation
The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IL4R | interleukin 4 receptor | 0.999 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.996 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.973 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.961 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.948 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.933 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.864 | |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.809 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.806 | |
| RXRA | retinoid X receptor, alpha | 0.777 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.774 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.730 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.693 | |
| TRAF3 | TNF receptor-associated factor 3 | 0.677 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.658 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.656 | |
| IL2RG | interleukin 2 receptor, gamma | 0.652 | |
| IL4 | interleukin 4 | 0.652 | |
| EP300 | E1A binding protein p300 | 0.549 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.496 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.455 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.433 | |
| HDAC4 | histone deacetylase 4 | 0.414 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.365 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.292 | |
| PDZD11 | PDZ domain containing 11 | 0.265 | |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.262 | |
| HDAC3 | histone deacetylase 3 | 0.223 | |
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.201 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.173 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.160 | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.158 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.147 | |
| KSR1 | kinase suppressor of ras 1 | 0.131 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.131 | |
| HDAC9 | histone deacetylase 9 | 0.130 | |
| IL6R | interleukin 6 receptor | 0.121 | |
| IL1B | interleukin 1, beta | 0.103 | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.103 | |
| LIN9 | lin-9 homolog (C. elegans) | 0.100 | |
| RARA | retinoic acid receptor, alpha | 0.100 | |
| HDAC7 | histone deacetylase 7 | 0.096 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.091 | |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.090 | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.085 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.080 | |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.078 | |
| E2F1 | E2F transcription factor 1 | 0.077 | |
| IL7R | interleukin 7 receptor | 0.076 | |
| PLXND1 | plexin D1 | 0.073 | |
| TANK | TRAF family member-associated NFKB activator | 0.069 | |
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.069 | |
| TNF | tumor necrosis factor | 0.069 | |
| MBD1 | methyl-CpG binding domain protein 1 | 0.068 | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.065 | |
| KLHL24 | kelch-like 24 (Drosophila) | 0.065 | |
| JUNB | jun B proto-oncogene | 0.065 | |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.064 | |
| C5orf41 | chromosome 5 open reading frame 41 | 0.064 | |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.063 | |
| HDAC5 | histone deacetylase 5 | 0.061 | |
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.058 | |
| LIN54 | lin-54 homolog (C. elegans) | 0.057 | |
| IL2RA | interleukin 2 receptor, alpha | 0.055 | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.054 | |
| ZNF148 | zinc finger protein 148 | 0.053 | |
| HDAC10 | histone deacetylase 10 | 0.052 | |
| PRKCE | protein kinase C, epsilon | 0.050 | |
| IRF1 | interferon regulatory factor 1 | 0.050 | |
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.050 | |
| PCDH9 | protocadherin 9 | 0.049 | |
| CREBBP | CREB binding protein | 0.048 | |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.048 | |
| IL8 | interleukin 8 | 0.048 | |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.047 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.045 | |
| FOSL2 | FOS-like antigen 2 | 0.044 | |
| CD83 | CD83 molecule | 0.043 | |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.043 | |
| CDK9 | cyclin-dependent kinase 9 | 0.043 | |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.041 | |
| IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 0.041 | |
| RUNX3 | runt-related transcription factor 3 | 0.040 | |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.040 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.039 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.038 | |
| IRF4 | interferon regulatory factor 4 | 0.038 | |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.038 | |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.037 | |
| PGR | progesterone receptor | 0.037 | |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 0.036 | |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.036 | |
| RXRB | retinoid X receptor, beta | 0.035 | |
| PRKD2 | protein kinase D2 | 0.034 | |
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.033 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.033 | |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.033 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.031 | |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.031 | |
| SPIN1 | spindlin 1 | 0.031 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 1.000 | |
| Tnf | tumor necrosis factor | 0.999 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.999 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.997 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.993 | |
| Cd40 | CD40 antigen | 0.988 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.985 | |
| Lepr | leptin receptor | 0.981 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.974 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.965 | |
| Jak2 | Janus kinase 2 | 0.963 | |
| Csf2rb2 | colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) | 0.953 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.951 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.943 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.924 | |
| Stat5a | signal transducer and activator of transcription 5A | 0.922 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.902 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.873 | |
| Il1r1 | interleukin 1 receptor, type I | 0.841 | |
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.839 | |
| Ifng | interferon gamma | 0.829 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.829 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.822 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.789 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.745 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.732 | |
| Lyz2 | lysozyme 2 | 0.721 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.711 | |
| Runx1 | runt related transcription factor 1 | 0.707 | |
| Irf9 | interferon regulatory factor 9 | 0.704 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.676 | |
| Cd19 | CD19 antigen | 0.658 | |
| Irf4 | interferon regulatory factor 4 | 0.655 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.642 | |
| Cd28 | CD28 antigen | 0.635 | |
| Gata6 | GATA binding protein 6 | 0.624 | |
| Msx1 | homeobox, msh-like 1 | 0.624 | |
| Cish | cytokine inducible SH2-containing protein | 0.624 | |
| Nf1 | neurofibromatosis 1 | 0.617 | |
| Creb1 | cAMP responsive element binding protein 1 | 0.608 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.605 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.594 | |
| Il6st | interleukin 6 signal transducer | 0.588 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.585 | |
| Tlr4 | toll-like receptor 4 | 0.580 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.564 | |
| Atxn1 | ataxin 1 | 0.563 | |
| Rarg | retinoic acid receptor, gamma | 0.556 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.539 | |
| Cd86 | CD86 antigen | 0.538 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.530 | |
| Hoxa1 | homeobox A1 | 0.522 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.514 | |
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.510 | |
| Icos | inducible T-cell co-stimulator | 0.506 | |
| Traf6 | TNF receptor-associated factor 6 | 0.493 | |
| Il4ra | interleukin 4 receptor, alpha | 0.491 | |
| Il2 | interleukin 2 | 0.471 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.460 | |
| Sfpi1 | SFFV proviral integration 1 | 0.456 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.456 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.448 | |
| Fgf10 | fibroblast growth factor 10 | 0.440 | |
| Sfn | stratifin | 0.431 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.428 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.424 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.416 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.411 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.410 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.408 | |
| Rxra | retinoid X receptor alpha | 0.398 | |
| Prf1 | perforin 1 (pore forming protein) | 0.397 | |
| Selp | selectin, platelet | 0.395 | |
| Foxp3 | forkhead box P3 | 0.393 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.390 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.385 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.366 | |
| Ppard | peroxisome proliferator activator receptor delta | 0.358 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.358 | |
| Icam1 | intercellular adhesion molecule 1 | 0.356 | |
| Traf1 | TNF receptor-associated factor 1 | 0.353 | |
| Shh | sonic hedgehog | 0.349 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.339 | |
| Il4 | interleukin 4 | 0.336 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.333 | |
| Prdm1 | PR domain containing 1, with ZNF domain | 0.322 | |
| Rara | retinoic acid receptor, alpha | 0.306 | |
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.295 | |
| Prkcd | protein kinase C, delta | 0.292 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.278 | |
| Ar | androgen receptor | 0.276 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.274 | |
| Jak3 | Janus kinase 3 | 0.264 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.249 | |
| Mxd1 | MAX dimerization protein 1 | 0.248 | |
| Dlx5 | distal-less homeobox 5 | 0.247 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.235 | |
| Mesp1 | mesoderm posterior 1 | 0.235 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.232 | |
| Ch25h | cholesterol 25-hydroxylase | 0.232 |