IMP
Process View
The network for 'negative regulation of posttranscriptional gene silencing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of posttranscriptional gene silencing
Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FOXD3 | forkhead box D3 | 1.000 | |
| SP1 | Sp1 transcription factor | 0.999 | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.997 | |
| PAX3 | paired box 3 | 0.995 | |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.992 | |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.972 | |
| HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.875 | |
| DAZL | deleted in azoospermia-like | 0.840 | |
| PUM2 | pumilio homolog 2 (Drosophila) | 0.768 | |
| CSNK2B | casein kinase 2, beta polypeptide | 0.749 | |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.595 | |
| EXOSC10 | exosome component 10 | 0.535 | |
| HTT | huntingtin | 0.502 | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.467 | |
| TARDBP | TAR DNA binding protein | 0.329 | |
| MOCS3 | molybdenum cofactor synthesis 3 | 0.323 | |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.294 | |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.227 | |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) | 0.181 | |
| MEOX2 | mesenchyme homeobox 2 | 0.138 | |
| CUL1 | cullin 1 | 0.126 | |
| HRK | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.124 | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.121 | |
| DTX3L | deltex 3-like (Drosophila) | 0.108 | |
| FTSJD2 | FtsJ methyltransferase domain containing 2 | 0.103 | |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.091 | |
| POGZ | pogo transposable element with ZNF domain | 0.089 | |
| SMAD7 | SMAD family member 7 | 0.072 | |
| HOXD12 | homeobox D12 | 0.069 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.065 | |
| NOVA2 | neuro-oncological ventral antigen 2 | 0.062 | |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.059 | |
| ESR2 | estrogen receptor 2 (ER beta) | 0.057 | |
| HMGA1 | high mobility group AT-hook 1 | 0.057 | |
| POU3F2 | POU class 3 homeobox 2 | 0.056 | |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.054 | |
| MOV10 | Mov10, Moloney leukemia virus 10, homolog (mouse) | 0.050 | |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.048 | |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.048 | |
| CHN2 | chimerin (chimaerin) 2 | 0.047 | |
| OTP | orthopedia homeobox | 0.044 | |
| TOP1 | topoisomerase (DNA) I | 0.043 | |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.042 | |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.041 | |
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.040 | |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.040 | |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.039 | |
| MEX3B | mex-3 homolog B (C. elegans) | 0.038 | |
| LHX1 | LIM homeobox 1 | 0.038 | |
| POU3F3 | POU class 3 homeobox 3 | 0.037 | |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.037 | |
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.037 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.036 | |
| NKX2-1 | NK2 homeobox 1 | 0.035 | |
| ATF7IP | activating transcription factor 7 interacting protein | 0.035 | |
| FHOD1 | formin homology 2 domain containing 1 | 0.034 | |
| ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.034 | |
| XIAP | X-linked inhibitor of apoptosis | 0.034 | |
| XPO7 | exportin 7 | 0.033 | |
| POU4F1 | POU class 4 homeobox 1 | 0.032 | |
| NEUROG3 | neurogenin 3 | 0.031 | |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.030 | |
| DZIP1 | DAZ interacting protein 1 | 0.029 | |
| GRIP1 | glutamate receptor interacting protein 1 | 0.028 | |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.027 | |
| ASCL1 | achaete-scute complex homolog 1 (Drosophila) | 0.025 | |
| DICER1 | dicer 1, ribonuclease type III | 0.025 | |
| ESR1 | estrogen receptor 1 | 0.025 | |
| POU3F4 | POU class 3 homeobox 4 | 0.023 | |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.023 | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.023 | |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.022 | |
| RAX | retina and anterior neural fold homeobox | 0.022 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.022 | |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.021 | |
| TLX2 | T-cell leukemia homeobox 2 | 0.021 | |
| NPAS1 | neuronal PAS domain protein 1 | 0.021 | |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.020 | |
| POU3F1 | POU class 3 homeobox 1 | 0.020 | |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 0.020 | |
| C10orf46 | chromosome 10 open reading frame 46 | 0.019 | |
| NKX6-1 | NK6 homeobox 1 | 0.019 | |
| DIDO1 | death inducer-obliterator 1 | 0.019 | |
| GATA5 | GATA binding protein 5 | 0.019 | |
| PURB | purine-rich element binding protein B | 0.019 | |
| RNF114 | ring finger protein 114 | 0.018 | |
| TP73 | tumor protein p73 | 0.018 | |
| PRMT2 | protein arginine methyltransferase 2 | 0.018 | |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.018 | |
| GALR1 | galanin receptor 1 | 0.018 | |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.018 | |
| ZBTB17 | zinc finger and BTB domain containing 17 | 0.017 | |
| MTA2 | metastasis associated 1 family, member 2 | 0.017 | |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | 0.017 | |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | 0.017 | |
| POU4F2 | POU class 4 homeobox 2 | 0.017 | |
| ZNF143 | zinc finger protein 143 | 0.017 | |
| NHLH2 | nescient helix loop helix 2 | 0.016 | |
| FLNB | filamin B, beta | 0.016 | |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 0.016 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Sall4 | sal-like 4 (Drosophila) | 0.999 | |
| Nanog | Nanog homeobox | 0.993 | |
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.980 | |
| Sall1 | sal-like 1 (Drosophila) | 0.666 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.611 | |
| Esrrb | estrogen related receptor, beta | 0.356 | |
| Sall3 | sal-like 3 (Drosophila) | 0.140 | |
| Sh3gl2 | SH3-domain GRB2-like 2 | 0.110 | |
| Sox2 | SRY-box containing gene 2 | 0.109 | |
| Rybp | RING1 and YY1 binding protein | 0.077 | |
| Rnf2 | ring finger protein 2 | 0.056 | |
| Mta1 | metastasis associated 1 | 0.052 | |
| Arid3b | AT rich interactive domain 3B (BRIGHT-like) | 0.050 | |
| Mta3 | metastasis associated 3 | 0.048 | |
| Gatad2b | GATA zinc finger domain containing 2B | 0.047 | |
| Zfp42 | zinc finger protein 42 | 0.045 | |
| Zic2 | zinc finger protein of the cerebellum 2 | 0.035 | |
| Rcor2 | REST corepressor 2 | 0.035 | |
| Rfx2 | regulatory factor X, 2 (influences HLA class II expression) | 0.034 | |
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.033 | |
| Grin2c | glutamate receptor, ionotropic, NMDA2C (epsilon 3) | 0.030 | |
| Fbxo15 | F-box protein 15 | 0.027 | |
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.024 | |
| Ep400 | E1A binding protein p400 | 0.023 | |
| Dnmt3l | DNA (cytosine-5-)-methyltransferase 3-like | 0.023 | |
| Dmc1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 0.023 | |
| Ybx2 | Y box protein 2 | 0.022 | |
| Zfp219 | zinc finger protein 219 | 0.022 | |
| Actn3 | actinin alpha 3 | 0.022 | |
| Dmrt1 | doublesex and mab-3 related transcription factor 1 | 0.021 | |
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 0.021 | |
| Naa11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit | 0.020 | |
| Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.019 | |
| Myst2 | MYST histone acetyltransferase 2 | 0.018 | |
| Dpep3 | dipeptidase 3 | 0.018 | |
| Hist3h2bb-ps | histone cluster 3, H2bb, pseudogene | 0.018 | |
| Sox15 | SRY-box containing gene 15 | 0.017 | |
| Cabin1 | calcineurin binding protein 1 | 0.017 | |
| Tsx | testis specific X-linked gene | 0.016 | |
| Hcfc1 | host cell factor C1 | 0.014 | |
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.014 | |
| Nfrkb | nuclear factor related to kappa B binding protein | 0.014 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.014 | |
| Klf5 | Kruppel-like factor 5 | 0.014 | |
| Mesp1 | mesoderm posterior 1 | 0.013 | |
| Trap1a | tumor rejection antigen P1A | 0.013 | |
| Baz2a | bromodomain adjacent to zinc finger domain, 2A | 0.012 | |
| Lig3 | ligase III, DNA, ATP-dependent | 0.012 | |
| Myl10 | myosin, light chain 10, regulatory | 0.012 | |
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.012 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.012 | |
| Trrap | transformation/transcription domain-associated protein | 0.011 | |
| Dppa5a | developmental pluripotency associated 5A | 0.011 | |
| Clgn | calmegin | 0.011 | |
| Fgf8 | fibroblast growth factor 8 | 0.011 | |
| Stat1 | signal transducer and activator of transcription 1 | 0.011 | |
| Ubn2 | ubinuclein 2 | 0.011 | |
| Pml | promyelocytic leukemia | 0.010 | |
| Dusp9 | dual specificity phosphatase 9 | 0.010 | |
| Phlda2 | pleckstrin homology-like domain, family A, member 2 | 0.010 | |
| Mta2 | metastasis-associated gene family, member 2 | 0.010 |