IMP
Process View
The network for 'regulation of macrophage differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of macrophage differentiation
Any process that modulates the frequency, rate or extent of macrophage differentiation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 1.000 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.997 | |
| XIAP | X-linked inhibitor of apoptosis | 0.997 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.990 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.988 | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.977 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.968 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.940 | |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.735 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.733 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.682 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.671 | |
| APAF1 | apoptotic peptidase activating factor 1 | 0.641 | |
| IL8 | interleukin 8 | 0.617 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.610 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.603 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.411 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.400 | |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.395 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.332 | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.331 | |
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.226 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.218 | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.201 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.176 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.164 | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.134 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.113 | |
| GHR | growth hormone receptor | 0.112 | |
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.079 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.076 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.066 | |
| TRAF3 | TNF receptor-associated factor 3 | 0.065 | |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.061 | |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.059 | |
| HDAC6 | histone deacetylase 6 | 0.046 | |
| LRDD | leucine-rich repeats and death domain containing | 0.042 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.040 | |
| SH2D4A | SH2 domain containing 4A | 0.039 | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.037 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.036 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.034 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.034 | |
| PF4 | platelet factor 4 | 0.033 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.031 | |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.022 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.022 | |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.020 | |
| IRF1 | interferon regulatory factor 1 | 0.019 | |
| HBB | hemoglobin, beta | 0.018 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.018 | |
| IL1B | interleukin 1, beta | 0.017 | |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.015 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.014 | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.014 | |
| OSMR | oncostatin M receptor | 0.014 | |
| UBD | ubiquitin D | 0.013 | |
| DBNL | drebrin-like | 0.013 | |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.012 | |
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.012 | |
| TANK | TRAF family member-associated NFKB activator | 0.012 | |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.011 | |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.011 | |
| BCL2A1 | BCL2-related protein A1 | 0.010 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| tal1 | T-cell acute lymphocytic leukemia 1 | 0.273 | |
| lmo2 | LIM domain only 2 (rhombotin-like 1) | 0.046 | |
| gata3 | GATA-binding protein 3 | 0.038 | |
| hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.028 | |
| drl | draculin | 0.017 | |
| irx3a | iroquois homeobox protein 3a | 0.017 | |
| mpped2 | metallophosphoesterase domain containing 2 | 0.011 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Id3 | inhibitor of DNA binding 3 | 0.859 | |
| Id1 | inhibitor of DNA binding 1 | 0.563 | |
| Gata4 | GATA binding protein 4 | 0.454 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.446 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.389 | |
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.337 | |
| Pten | phosphatase and tensin homolog | 0.335 | |
| Ldb3 | LIM domain binding 3 | 0.323 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.283 | |
| Fgd1 | FYVE, RhoGEF and PH domain containing 1 | 0.277 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.273 | |
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.255 | |
| Jag1 | jagged 1 | 0.192 | |
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.191 | |
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.143 | |
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.133 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.132 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.130 | |
| Src | Rous sarcoma oncogene | 0.110 | |
| Csf1r | colony stimulating factor 1 receptor | 0.110 | |
| Igh | immunoglobulin heavy chain complex | 0.101 | |
| Gata6 | GATA binding protein 6 | 0.093 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.092 | |
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.086 | |
| Nf1 | neurofibromatosis 1 | 0.085 | |
| Trp53 | transformation related protein 53 | 0.082 | |
| Kit | kit oncogene | 0.080 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.080 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.078 | |
| Casp8 | caspase 8 | 0.069 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.067 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.066 | |
| Rb1 | retinoblastoma 1 | 0.065 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.063 | |
| Tcf3 | transcription factor 3 | 0.062 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.058 | |
| Apaf1 | apoptotic peptidase activating factor 1 | 0.057 | |
| Lyz2 | lysozyme 2 | 0.055 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.055 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.055 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.054 | |
| Sox4 | SRY-box containing gene 4 | 0.052 | |
| Tcf4 | transcription factor 4 | 0.050 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.048 | |
| Kitl | kit ligand | 0.047 | |
| Alox5ap | arachidonate 5-lipoxygenase activating protein | 0.047 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.043 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.042 | |
| Dll1 | delta-like 1 (Drosophila) | 0.041 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.038 | |
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.036 | |
| Tcirg1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 | 0.033 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.033 | |
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.033 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.032 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.030 | |
| Itgb2 | integrin beta 2 | 0.030 | |
| Rxra | retinoid X receptor alpha | 0.028 | |
| Col1a1 | collagen, type I, alpha 1 | 0.028 | |
| Ifngr1 | interferon gamma receptor 1 | 0.027 | |
| Pkdcc | protein kinase domain containing, cytoplasmic | 0.025 | |
| Tbx3 | T-box 3 | 0.025 | |
| Hs1bp3 | HCLS1 binding protein 3 | 0.024 | |
| Myo6 | myosin VI | 0.024 | |
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.024 | |
| Gja1 | gap junction protein, alpha 1 | 0.024 | |
| Traf6 | TNF receptor-associated factor 6 | 0.024 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.023 | |
| Fyb | FYN binding protein | 0.022 | |
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.022 | |
| Cyld | cylindromatosis (turban tumor syndrome) | 0.022 | |
| Actn2 | actinin alpha 2 | 0.021 | |
| Il6st | interleukin 6 signal transducer | 0.020 | |
| Plcd1 | phospholipase C, delta 1 | 0.020 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.019 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.019 | |
| Ncoa1 | nuclear receptor coactivator 1 | 0.019 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.019 | |
| Shank3 | SH3/ankyrin domain gene 3 | 0.018 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.018 | |
| Cfp | complement factor properdin | 0.018 | |
| Psen1 | presenilin 1 | 0.017 | |
| Prkce | protein kinase C, epsilon | 0.017 | |
| Ly86 | lymphocyte antigen 86 | 0.017 | |
| C3 | complement component 3 | 0.017 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.017 | |
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 0.017 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.016 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.015 | |
| Bmp4 | bone morphogenetic protein 4 | 0.015 | |
| Ctss | cathepsin S | 0.015 | |
| Runx1 | runt related transcription factor 1 | 0.015 | |
| Hhex | hematopoietically expressed homeobox | 0.015 | |
| Sgpl1 | sphingosine phosphate lyase 1 | 0.014 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.014 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.014 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.014 | |
| Rbl1 | retinoblastoma-like 1 (p107) | 0.014 | |
| Yap1 | yes-associated protein 1 | 0.013 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.013 |