The network for 'negative regulation of viral process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of viral process

Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.

Homo sapiens
Name Description Probability Func Analog Organism
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.999
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.999
SP110 SP110 nuclear body protein 0.998
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.995
IFI44L interferon-induced protein 44-like 0.994
IFI44 interferon-induced protein 44 0.993
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.993
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.990
ISG15 ISG15 ubiquitin-like modifier 0.989
SP100 SP100 nuclear antigen 0.987
STAT1 signal transducer and activator of transcription 1, 91kDa 0.973
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.966
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.927
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.920
IFIH1 interferon induced with helicase C domain 1 0.913
IRF9 interferon regulatory factor 9 0.912
TRIM21 tripartite motif containing 21 0.909
IFI35 interferon-induced protein 35 0.905
HDAC1 histone deacetylase 1 0.903
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.900
DTX3L deltex 3-like (Drosophila) 0.894
SP1 Sp1 transcription factor 0.877
XAF1 XIAP associated factor 1 0.834
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.832
PARP12 poly (ADP-ribose) polymerase family, member 12 0.822
SAMD9 sterile alpha motif domain containing 9 0.800
IFI6 interferon, alpha-inducible protein 6 0.784
OASL 2'-5'-oligoadenylate synthetase-like 0.768
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.722
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.709
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.661
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.650
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.633
PLSCR1 phospholipid scramblase 1 0.575
CCR5 chemokine (C-C motif) receptor 5 0.568
JUN jun proto-oncogene 0.534
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.531
FOS FBJ murine osteosarcoma viral oncogene homolog 0.494
TRIM63 tripartite motif containing 63 0.493
IRF7 interferon regulatory factor 7 0.469
GFM1 G elongation factor, mitochondrial 1 0.453
TRIM41 tripartite motif containing 41 0.450
PML promyelocytic leukemia 0.447
SAMD9L sterile alpha motif domain containing 9-like 0.443
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.412
CCL4 chemokine (C-C motif) ligand 4 0.400
IFI27 interferon, alpha-inducible protein 27 0.395
TRIM43 tripartite motif containing 43 0.376
UBE2U ubiquitin-conjugating enzyme E2U (putative) 0.356
TRIM5 tripartite motif containing 5 0.353
ADAR adenosine deaminase, RNA-specific 0.329
C19orf66 chromosome 19 open reading frame 66 0.289
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.284
BST2 bone marrow stromal cell antigen 2 0.267
HERC5 hect domain and RLD 5 0.259
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.255
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.251
STAT2 signal transducer and activator of transcription 2, 113kDa 0.245
TRIM39 tripartite motif containing 39 0.239
MED15 mediator complex subunit 15 0.239
ESR1 estrogen receptor 1 0.226
SMAD4 SMAD family member 4 0.218
RSAD2 radical S-adenosyl methionine domain containing 2 0.217
LIN28B lin-28 homolog B (C. elegans) 0.199
CCL5 chemokine (C-C motif) ligand 5 0.187
FOXD3 forkhead box D3 0.187
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.186
EPSTI1 epithelial stromal interaction 1 (breast) 0.179
MYD88 myeloid differentiation primary response gene (88) 0.167
RTP4 receptor (chemosensory) transporter protein 4 0.166
CCL8 chemokine (C-C motif) ligand 8 0.158
IFI16 interferon, gamma-inducible protein 16 0.154
THOC4 THO complex 4 0.150
IFITM2 interferon induced transmembrane protein 2 (1-8D) 0.140
CXCL9 chemokine (C-X-C motif) ligand 9 0.137
SOX10 SRY (sex determining region Y)-box 10 0.126
HNF4A hepatocyte nuclear factor 4, alpha 0.117
TMEM173 transmembrane protein 173 0.114
ATF3 activating transcription factor 3 0.112
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.108
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.104
HMGA1 high mobility group AT-hook 1 0.104
TDRD7 tudor domain containing 7 0.103
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) 0.099
ZNFX1 zinc finger, NFX1-type containing 1 0.099
TRIM26 tripartite motif containing 26 0.096
TRIM22 tripartite motif containing 22 0.096
CXCL10 chemokine (C-X-C motif) ligand 10 0.094
KDM6A lysine (K)-specific demethylase 6A 0.093
MAGEA4 melanoma antigen family A, 4 0.087
PAX3 paired box 3 0.083
RNF5 ring finger protein 5 0.081
RNF126 ring finger protein 126 0.079
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.079
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.079
SKIL SKI-like oncogene 0.078
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.076
GBP1 guanylate binding protein 1, interferon-inducible 0.074
USP18 ubiquitin specific peptidase 18 0.074
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.073
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
phl pole hole 0.026
Dl Delta 0.020
sax saxophone 0.017
N Notch 0.011
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.996
Trim30a tripartite motif-containing 30A 0.993
Irf7 interferon regulatory factor 7 0.992
Rsad2 radical S-adenosyl methionine domain containing 2 0.984
Usp18 ubiquitin specific peptidase 18 0.983
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.969
Isg15 ISG15 ubiquitin-like modifier 0.962
Rtp4 receptor transporter protein 4 0.890
Ifitm3 interferon induced transmembrane protein 3 0.888
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.875
Ifi44 interferon-induced protein 44 0.850
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.819
Uba7 ubiquitin-like modifier activating enzyme 7 0.796
Irgm1 immunity-related GTPase family M member 1 0.796
Gbp7 guanylate binding protein 7 0.788
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.729
BC006779 cDNA sequence BC006779 0.719
Irgm2 immunity-related GTPase family M member 2 0.698
Parp14 poly (ADP-ribose) polymerase family, member 14 0.664
Igtp interferon gamma induced GTPase 0.607
Ifih1 interferon induced with helicase C domain 1 0.579
Irf9 interferon regulatory factor 9 0.563
Oas2 2'-5' oligoadenylate synthetase 2 0.479
Stat1 signal transducer and activator of transcription 1 0.456
Mndal myeloid nuclear differentiation antigen like 0.438
Ifi47 interferon gamma inducible protein 47 0.418
Oas1a 2'-5' oligoadenylate synthetase 1A 0.399
Samd9l sterile alpha motif domain containing 9-like 0.397
Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.390
Mx2 myxovirus (influenza virus) resistance 2 0.389
Ifi35 interferon-induced protein 35 0.378
Oas3 2'-5' oligoadenylate synthetase 3 0.376
Trim30d tripartite motif-containing 30D 0.364
Zbp1 Z-DNA binding protein 1 0.358
Oasl1 2'-5' oligoadenylate synthetase-like 1 0.352
Parp9 poly (ADP-ribose) polymerase family, member 9 0.344
Stat2 signal transducer and activator of transcription 2 0.318
Tor3a torsin family 3, member A 0.317
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.291
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.281
Mx1 myxovirus (influenza virus) resistance 1 0.265
Gbp3 guanylate binding protein 3 0.252
Cmpk2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.225
Ube2l6 ubiquitin-conjugating enzyme E2L 6 0.212
Trim21 tripartite motif-containing 21 0.206
Gbp2 guanylate binding protein 2 0.196
Slfn4 schlafen 4 0.181
Ly6a lymphocyte antigen 6 complex, locus A 0.143
Nanog Nanog homeobox 0.135
Dtx3l deltex 3-like (Drosophila) 0.126
Tgtp2 T-cell specific GTPase 2 0.122
Gm12185 predicted gene 12185 0.122
Tmem106a transmembrane protein 106A 0.118
Xaf1 XIAP associated factor 1 0.114
Lgals9 lectin, galactose binding, soluble 9 0.105
Oas1b 2'-5' oligoadenylate synthetase 1B 0.104
Ifi27l2a interferon, alpha-inducible protein 27 like 2A 0.103
Pml promyelocytic leukemia 0.099
Tapbp TAP binding protein 0.098
D14Ertd668e DNA segment, Chr 14, ERATO Doi 668, expressed 0.096
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.087
Cxcl10 chemokine (C-X-C motif) ligand 10 0.083
Iigp1 interferon inducible GTPase 1 0.079
Herc6 hect domain and RLD 6 0.078
Hnrnpm heterogeneous nuclear ribonucleoprotein M 0.077
Parp12 poly (ADP-ribose) polymerase family, member 12 0.073
Ccl2 chemokine (C-C motif) ligand 2 0.071
Hdac2 histone deacetylase 2 0.069
Trim12a tripartite motif-containing 12A 0.067
Ccrl2 chemokine (C-C motif) receptor-like 2 0.065
Trim34a tripartite motif-containing 34A 0.065
Sprr2k small proline-rich protein 2K 0.065
Zc3hav1 zinc finger CCCH type, antiviral 1 0.064
Trim25 tripartite motif-containing 25 0.063
Sp100 nuclear antigen Sp100 0.063
Daxx Fas death domain-associated protein 0.062
Irf1 interferon regulatory factor 1 0.060
Ifi203 interferon activated gene 203 0.060
Eif2c1 eukaryotic translation initiation factor 2C, 1 0.058
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.055
Trim28 tripartite motif-containing 28 0.052
Atf3 activating transcription factor 3 0.052
H2-T24 histocompatibility 2, T region locus 24 0.050
Slfn2 schlafen 2 0.048
Ifit2 interferon-induced protein with tetratricopeptide repeats 2 0.047
Slfn8 schlafen 8 0.044
Htt huntingtin 0.044
Plac8 placenta-specific 8 0.043
Epsti1 epithelial stromal interaction 1 (breast) 0.042
Trim55 tripartite motif-containing 55 0.037
Trim12c tripartite motif-containing 12C 0.036
Ifitm2 interferon induced transmembrane protein 2 0.035
Fos FBJ osteosarcoma oncogene 0.035
U2af2 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 0.034
Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 0.033
Ifna9 interferon alpha 9 0.033
Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 0.032
Hck hemopoietic cell kinase 0.032
Ly6e lymphocyte antigen 6 complex, locus E 0.030
Traf3 TNF receptor-associated factor 3 0.028
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Usp18 ubiquitin specific peptidase 18 0.353
Irf7 interferon regulatory factor 7 0.187
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.167
Ifitm2 interferon induced transmembrane protein 2 0.107
Dusp1 dual specificity phosphatase 1 0.068
Mx1 myxovirus (influenza virus) resistance 1 0.062
Il1b interleukin 1 beta 0.053
Nkg7 natural killer cell group 7 sequence 0.052
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.048
Mgp matrix Gla protein 0.045
Srm spermidine synthase 0.043
Ifitm1 interferon induced transmembrane protein 1 0.043
Cxcl10 chemokine (C-X-C motif) ligand 10 0.042
S100a6 S100 calcium binding protein A6 0.040
Il2rb interleukin 2 receptor, beta 0.040
Oasl 2'-5'-oligoadenylate synthetase-like 0.036
Ccl4 chemokine (C-C motif) ligand 4 0.034
Ifitm3 interferon induced transmembrane protein 3 0.031
Ipo4 importin 4 0.031
Sp110 SP110 nuclear body protein 0.031
Cxcl2 chemokine (C-X-C motif) ligand 2 0.030
Oas1a 2'-5' oligoadenylate synthetase 1A 0.029
Gtf2i general transcription factor II I 0.028
Cfb complement factor B 0.028
Gzmc granzyme C 0.027
Oas1b 2-5 oligoadenylate synthetase 1B 0.026
Ly6c Ly6-C antigen 0.026
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.026
Rnf213 ring finger protein 213 0.025
Brcc3 BRCA1/BRCA2-containing complex, subunit 3 0.025
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.025
C1s complement component 1, s subcomponent 0.025
Timp1 TIMP metallopeptidase inhibitor 1 0.024
Sp140 SP140 nuclear body protein 0.022
Srgn serglycin 0.022
Klf6 Kruppel-like factor 6 0.022
Irf9 interferon regulatory factor 9 0.022
Mmp8 matrix metallopeptidase 8 0.021
Uba7 ubiquitin-like modifier activating enzyme 7 0.021
Ss18 synovial sarcoma translocation, Chromosome 18 0.021
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.021
S100a11 S100 calcium binding protein A11 (calizzarin) 0.020
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.020
Gzmk granzyme K 0.020
Il2rg interleukin 2 receptor, gamma 0.020
Caprin1 cell cycle associated protein 1 0.020
Gja6 gap junction protein, alpha 6 0.019
C1r complement component 1, r subcomponent 0.019
Cp ceruloplasmin 0.019
Gzmb granzyme B 0.019
Dcn decorin 0.018
Isg15 ISG15 ubiquitin-like modifier 0.018
Mbtps1 membrane-bound transcription factor peptidase, site 1 0.018
Plac8 placenta-specific 8 0.018
Cxcr3 chemokine (C-X-C motif) receptor 3 0.018
Nradd neurotrophin receptor associated death domain 0.018
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.018
Myd88 myeloid differentiation primary response gene 88 0.018
Fam18b2 family with sequence similarity 18, member B2 0.017
Neurl3 neuralized homolog 3 (Drosophila) 0.017
Atf3 activating transcription factor 3 0.017
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.017
Stat2 signal transducer and activator of transcription 2 0.017
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.017
Prf1 perforin 1 (pore forming protein) 0.017
Bst2 bone marrow stromal cell antigen 2 0.017
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.017
Cxcl9 chemokine (C-X-C motif) ligand 9 0.017
Slfn3 schlafen 3 0.016
Pla1a phospholipase A1 member A 0.016
Mmp12 matrix metallopeptidase 12 0.016
Shisa5 shisa homolog 5 (Xenopus laevis) 0.016
Sf3b4 splicing factor 3b, subunit 4 0.016
Gbp2 guanylate binding protein 2 0.016
Isg20 interferon stimulated exonuclease gene 20 0.016
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.016
Cxcl13 chemokine (C-X-C motif) ligand 13 0.016
Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.015
Atl3 atlastin GTPase 3 0.015
Mcpt8 mast cell protease 8 0.015
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.015
Xdh xanthine dehydrogenase 0.015
Napsa napsin A aspartic peptidase 0.015
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.015
Anxa1 annexin A1 0.015
Fam115c family with sequence similarity 115, member C 0.015
Gzma granzyme A 0.015
Ifi44l interferon-induced protein 44-like 0.015
LOC606294 hypothetical protein LOC606294 0.015
LOC100364500 RT1 class I, locus CE11-like 0.015
Hcst hematopoietic cell signal transducer 0.015
Cd247 Cd247 molecule 0.015
Cenpj centromere protein J 0.015
RGD1309492 similar to mKIAA1737 protein 0.015
Gprasp1 G protein-coupled receptor associated sorting protein 1 0.014
Oas1i 2 ' -5 ' oligoadenylate synthetase 1I 0.014
Ifi44 interferon-induced protein 44 0.014
Med30 mediator complex subunit 30 0.014
Ccl20 chemokine (C-C motif) ligand 20 0.014
Pnrc2 proline-rich nuclear receptor coactivator 2 0.014
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism