The network for 'inflammatory cell apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

inflammatory cell apoptotic process

Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.

Homo sapiens
Name Description Probability Func Analog Organism
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.658
CCR5 chemokine (C-C motif) receptor 5 0.638
FASLG Fas ligand (TNF superfamily, member 6) 0.491
DERL1 Der1-like domain family, member 1 0.476
EP300 E1A binding protein p300 0.296
FADD Fas (TNFRSF6)-associated via death domain 0.266
CCL5 chemokine (C-C motif) ligand 5 0.238
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.222
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.210
MSN moesin 0.198
HDAC4 histone deacetylase 4 0.147
IL6R interleukin 6 receptor 0.137
CAV1 caveolin 1, caveolae protein, 22kDa 0.121
VCP valosin containing protein 0.094
CFLAR CASP8 and FADD-like apoptosis regulator 0.089
CAV2 caveolin 2 0.072
SYK spleen tyrosine kinase 0.070
CXCR4 chemokine (C-X-C motif) receptor 4 0.060
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.050
ANXA5 annexin A5 0.042
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.040
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.039
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.037
HDAC9 histone deacetylase 9 0.034
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.034
KAT2B K(lysine) acetyltransferase 2B 0.033
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.031
CCR1 chemokine (C-C motif) receptor 1 0.031
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.029
CXCR6 chemokine (C-X-C motif) receptor 6 0.029
CDK6 cyclin-dependent kinase 6 0.029
IL8 interleukin 8 0.027
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.026
CSF1R colony stimulating factor 1 receptor 0.024
PROCR protein C receptor, endothelial 0.023
BID BH3 interacting domain death agonist 0.023
VCAM1 vascular cell adhesion molecule 1 0.023
MEF2A myocyte enhancer factor 2A 0.021
CLEC7A C-type lectin domain family 7, member A 0.021
AHR aryl hydrocarbon receptor 0.021
IL1R2 interleukin 1 receptor, type II 0.020
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.020
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.020
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.020
CCND3 cyclin D3 0.019
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.018
FN1 fibronectin 1 0.017
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.017
RAD52 RAD52 homolog (S. cerevisiae) 0.017
CREBBP CREB binding protein 0.017
EZR ezrin 0.017
CLEC4A C-type lectin domain family 4, member A 0.016
DERL2 Der1-like domain family, member 2 0.016
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.016
SMAD7 SMAD family member 7 0.016
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.016
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.016
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.015
GPR171 G protein-coupled receptor 171 0.015
CCL4 chemokine (C-C motif) ligand 4 0.015
SPTBN1 spectrin, beta, non-erythrocytic 1 0.015
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.015
CLEC2B C-type lectin domain family 2, member B 0.015
GADD45A growth arrest and DNA-damage-inducible, alpha 0.015
CCL2 chemokine (C-C motif) ligand 2 0.015
GLIPR1 GLI pathogenesis-related 1 0.014
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.014
GIMAP4 GTPase, IMAP family member 4 0.014
RUNX1 runt-related transcription factor 1 0.013
ANXA2 annexin A2 0.013
SLAMF1 signaling lymphocytic activation molecule family member 1 0.013
STK17A serine/threonine kinase 17a 0.013
TFEC transcription factor EC 0.013
SLAMF7 SLAM family member 7 0.013
PRKCDBP protein kinase C, delta binding protein 0.013
EVI2A ecotropic viral integration site 2A 0.013
SRGN serglycin 0.013
INADL InaD-like (Drosophila) 0.013
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 0.013
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.013
SLC7A11 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 0.012
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 0.012
GPR109B G protein-coupled receptor 109B 0.012
IL7R interleukin 7 receptor 0.012
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.012
FGL2 fibrinogen-like 2 0.012
CXCL9 chemokine (C-X-C motif) ligand 9 0.012
DPP4 dipeptidyl-peptidase 4 0.012
CXCL10 chemokine (C-X-C motif) ligand 10 0.012
IFNG interferon, gamma 0.011
CCR2 chemokine (C-C motif) receptor 2 0.011
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.011
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.011
IL18R1 interleukin 18 receptor 1 0.011
CD72 CD72 molecule 0.011
TLR7 toll-like receptor 7 0.011
CD59 CD59 molecule, complement regulatory protein 0.011
DUSP10 dual specificity phosphatase 10 0.011
FOXO3 forkhead box O3 0.011
GPR65 G protein-coupled receptor 65 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.996
Ccr2 chemokine (C-C motif) receptor 2 0.964
Cd44 CD44 antigen 0.955
Lyz2 lysozyme 2 0.943
Tnf tumor necrosis factor 0.787
Ifng interferon gamma 0.784
Ccl3 chemokine (C-C motif) ligand 3 0.713
Il10 interleukin 10 0.658
Foxp3 forkhead box P3 0.576
Tlr4 toll-like receptor 4 0.560
Ccr1 chemokine (C-C motif) receptor 1 0.558
Il1b interleukin 1 beta 0.516
Cd19 CD19 antigen 0.463
Mmp9 matrix metallopeptidase 9 0.415
Ccr5 chemokine (C-C motif) receptor 5 0.390
Ccl7 chemokine (C-C motif) ligand 7 0.389
Il1r1 interleukin 1 receptor, type I 0.353
S100a6 S100 calcium binding protein A6 (calcyclin) 0.291
Pdcd1 programmed cell death 1 0.256
Gzmk granzyme K 0.239
Ccl4 chemokine (C-C motif) ligand 4 0.209
S100a11 S100 calcium binding protein A11 (calgizzarin) 0.204
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.187
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.171
Lgals3 lectin, galactose binding, soluble 3 0.165
Selp selectin, platelet 0.157
Anxa5 annexin A5 0.142
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.138
Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a 0.136
Pparg peroxisome proliferator activated receptor gamma 0.135
Nos2 nitric oxide synthase 2, inducible 0.127
Ccl8 chemokine (C-C motif) ligand 8 0.114
Tlr2 toll-like receptor 2 0.109
Fasl Fas ligand (TNF superfamily, member 6) 0.108
Casp1 caspase 1 0.105
Il6 interleukin 6 0.098
Ccl12 chemokine (C-C motif) ligand 12 0.097
Prf1 perforin 1 (pore forming protein) 0.095
Il6st interleukin 6 signal transducer 0.095
Fas Fas (TNF receptor superfamily member 6) 0.090
S100a10 S100 calcium binding protein A10 (calpactin) 0.088
Hdac4 histone deacetylase 4 0.087
Icam1 intercellular adhesion molecule 1 0.085
Ubd ubiquitin D 0.078
Ifngr1 interferon gamma receptor 1 0.076
Cd40 CD40 antigen 0.071
Socs1 suppressor of cytokine signaling 1 0.071
S100a4 S100 calcium binding protein A4 0.070
Sh2d2a SH2 domain protein 2A 0.067
Icos inducible T-cell co-stimulator 0.066
Il27ra interleukin 27 receptor, alpha 0.064
Il1rn interleukin 1 receptor antagonist 0.064
Gzmb granzyme B 0.063
Itgax integrin alpha X 0.062
Irg1 immunoresponsive gene 1 0.062
C3ar1 complement component 3a receptor 1 0.061
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.061
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.059
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.058
Hdac5 histone deacetylase 5 0.057
Cxcl9 chemokine (C-X-C motif) ligand 9 0.052
Lgals1 lectin, galactose binding, soluble 1 0.052
Fcgr2b Fc receptor, IgG, low affinity IIb 0.049
Il1a interleukin 1 alpha 0.049
Spp1 secreted phosphoprotein 1 0.047
Lta lymphotoxin A 0.046
Cd8a CD8 antigen, alpha chain 0.044
Cd7 CD7 antigen 0.044
Ccl22 chemokine (C-C motif) ligand 22 0.044
Batf basic leucine zipper transcription factor, ATF-like 0.043
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.043
Ccl17 chemokine (C-C motif) ligand 17 0.041
Il4 interleukin 4 0.041
Csf1 colony stimulating factor 1 (macrophage) 0.041
Myd88 myeloid differentiation primary response gene 88 0.040
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.040
Mmp12 matrix metallopeptidase 12 0.040
Ch25h cholesterol 25-hydroxylase 0.039
Ccr7 chemokine (C-C motif) receptor 7 0.038
Nupr1 nuclear protein 1 0.037
Cxcl13 chemokine (C-X-C motif) ligand 13 0.036
Prdm1 PR domain containing 1, with ZNF domain 0.036
Pdcd1lg2 programmed cell death 1 ligand 2 0.035
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.034
Mefv Mediterranean fever 0.033
Cxcl2 chemokine (C-X-C motif) ligand 2 0.033
Slamf1 signaling lymphocytic activation molecule family member 1 0.033
Cd28 CD28 antigen 0.031
Cd96 CD96 antigen 0.030
Pycard PYD and CARD domain containing 0.030
Ctsw cathepsin W 0.029
Itk IL2-inducible T-cell kinase 0.029
Cxcl1 chemokine (C-X-C motif) ligand 1 0.029
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.029
Cd6 CD6 antigen 0.028
Il12rb2 interleukin 12 receptor, beta 2 0.027
Gzmc granzyme C 0.027
Flt3 FMS-like tyrosine kinase 3 0.027
Xcl1 chemokine (C motif) ligand 1 0.027
Ccr6 chemokine (C-C motif) receptor 6 0.026
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Rattus norvegicus
Name Description Probability Func Analog Organism
Lgals3 lectin, galactoside-binding, soluble, 3 0.494
Cd247 Cd247 molecule 0.220
Aif1 allograft inflammatory factor 1 0.218
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.156
Gzmk granzyme K 0.145
Casp1 caspase 1 0.132
Ptprc protein tyrosine phosphatase, receptor type, C 0.095
Cd14 CD14 molecule 0.088
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.086
Vcan versican 0.078
Hck hemopoietic cell kinase 0.070
Selp selectin P 0.062
C1qb complement component 1, q subcomponent, B chain 0.057
Cd2 Cd2 molecule 0.054
Il8rb interleukin 8 receptor, beta 0.052
Faslg Fas ligand (TNF superfamily, member 6) 0.051
Ncr1 natural cytotoxicity triggering receptor 1 0.051
Clec10a C-type lectin domain family 10, member A 0.050
Il1a interleukin 1 alpha 0.041
Cd53 Cd53 molecule 0.035
Ccl22 chemokine (C-C motif) ligand 22 0.035
Timp1 TIMP metallopeptidase inhibitor 1 0.034
Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 0.032
Ccl2 chemokine (C-C motif) ligand 2 0.030
Lox lysyl oxidase 0.029
Dab2 disabled homolog 2 (Drosophila) 0.028
Tcrb T-cell receptor beta chain 0.028
Nkg7 natural killer cell group 7 sequence 0.027
Tgfbr3 transforming growth factor, beta receptor III 0.026
Cxcr3 chemokine (C-X-C motif) receptor 3 0.026
Ccl3 chemokine (C-C motif) ligand 3 0.025
Cd8a CD8a molecule 0.025
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.022
Anxa2 annexin A2 0.021
Cd86 CD86 molecule 0.020
Mmp8 matrix metallopeptidase 8 0.020
Tas2r126 taste receptor, type 2, member 126 0.020
Il9r interleukin 9 receptor 0.019
Clec9a C-type lectin domain family 9, member a 0.019
Klrc1 killer cell lectin-like receptor subfamily C, member 1 0.019
Cxcl13 chemokine (C-X-C motif) ligand 13 0.018
Mdfic MyoD family inhibitor domain containing 0.018
Ccl4 chemokine (C-C motif) ligand 4 0.017
Kif6 kinesin family member 6 0.017
Alox5ap arachidonate 5-lipoxygenase activating protein 0.017
C1s complement component 1, s subcomponent 0.017
Litaf lipopolysaccharide-induced TNF factor 0.017
Anxa1 annexin A1 0.016
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.015
Ccl5 chemokine (C-C motif) ligand 5 0.015
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.014
Fgl2 fibrinogen-like 2 0.013
Nsun2 NOL1/NOP2/Sun domain family, member 2 0.013
Adora2a adenosine A2a receptor 0.013
Cd3e CD3 molecule, epsilon 0.012
Prss21 protease, serine, 21 0.012
Cpa3 carboxypeptidase A3, mast cell 0.011
Il1b interleukin 1 beta 0.011
Igh-6 immunoglobulin heavy chain 6 0.011
Sell selectin L 0.011
Klrc2 killer cell lectin-like receptor subfamily C, member 2 0.010
RGD1559588 similar to cell surface receptor FDFACT 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism