The network for 'positive regulation of growth hormone secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of growth hormone secretion

Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.

Name Description Probability Func Analog Organism
Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 0.382
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.233
Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 0.144
Manf mesencephalic astrocyte-derived neurotrophic factor 0.105
Hspa5 heat shock protein 5 0.093
Nos1 nitric oxide synthase 1, neuronal 0.086
Mgat2 mannoside acetylglucosaminyltransferase 2 0.079
Pdx1 pancreatic and duodenal homeobox 1 0.077
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.077
Oprm1 opioid receptor, mu 1 0.068
Klk4 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) 0.067
Drd1a dopamine receptor D1A 0.065
Pgr progesterone receptor 0.063
Pitx3 paired-like homeodomain transcription factor 3 0.063
Pdia3 protein disulfide isomerase associated 3 0.062
Lep leptin 0.058
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.058
Cd247 CD247 antigen 0.055
H47 histocompatibility 47 0.055
Smpd3 sphingomyelin phosphodiesterase 3, neutral 0.051
Rs1 retinoschisis (X-linked, juvenile) 1 (human) 0.050
Pthlh parathyroid hormone-like peptide 0.045
Gnao1 guanine nucleotide binding protein, alpha O 0.045
Mc1r melanocortin 1 receptor 0.045
Gpr27 G protein-coupled receptor 27 0.044
Ihh Indian hedgehog 0.043
Prop1 paired like homeodomain factor 1 0.041
Prlr prolactin receptor 0.041
Oprk1 opioid receptor, kappa 1 0.039
App amyloid beta (A4) precursor protein 0.039
Tacr2 tachykinin receptor 2 0.038
Ostc oligosaccharyltransferase complex subunit 0.038
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.037
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.037
Gsx1 GS homeobox 1 0.036
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.036
Angpt4 angiopoietin 4 0.035
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.035
Apoa5 apolipoprotein A-V 0.034
Xbp1 X-box binding protein 1 0.034
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.034
Mc5r melanocortin 5 receptor 0.033
Gabrq gamma-aminobutyric acid (GABA) A receptor, subunit theta 0.032
Adm adrenomedullin 0.031
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.031
Tshr thyroid stimulating hormone receptor 0.030
Rhbdf1 rhomboid family 1 (Drosophila) 0.029
Cacng5 calcium channel, voltage-dependent, gamma subunit 5 0.029
4921517D21Rik RIKEN cDNA 4921517D21 gene 0.029
Hes2 hairy and enhancer of split 2 (Drosophila) 0.029
Crb3 crumbs homolog 3 (Drosophila) 0.028
Smyd1 SET and MYND domain containing 1 0.028
Olfr70 olfactory receptor 70 0.028
Asgr1 asialoglycoprotein receptor 1 0.028
Kl klotho 0.028
Rtbdn retbindin 0.027
Gm12597 predicted gene 12597 0.027
Emx1 empty spiracles homolog 1 (Drosophila) 0.027
Shc3 src homology 2 domain-containing transforming protein C3 0.026
Ghr growth hormone receptor 0.026
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.026
Slc30a5 solute carrier family 30 (zinc transporter), member 5 0.026
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.025
Tacr1 tachykinin receptor 1 0.025
Syt10 synaptotagmin X 0.025
Dlg4 discs, large homolog 4 (Drosophila) 0.025
Aatk apoptosis-associated tyrosine kinase 0.025
Cckbr cholecystokinin B receptor 0.025
Prl prolactin 0.024
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.024
Wnt2b wingless related MMTV integration site 2b 0.024
Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) 0.023
Sstr4 somatostatin receptor 4 0.023
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.023
4930451I11Rik RIKEN cDNA 4930451I11 gene 0.023
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.023
Prodh2 proline dehydrogenase (oxidase) 2 0.023
Btn1a1 butyrophilin, subfamily 1, member A1 0.023
Oprd1 opioid receptor, delta 1 0.023
Eda ectodysplasin-A 0.022
Guca2b guanylate cyclase activator 2b (retina) 0.022
Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) 0.022
Fshb follicle stimulating hormone beta 0.022
Sstr1 somatostatin receptor 1 0.022
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.022
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.022
Hoxb1 homeobox B1 0.022
Gmppb GDP-mannose pyrophosphorylase B 0.021
Mchr1 melanin-concentrating hormone receptor 1 0.021
Matn1 matrilin 1, cartilage matrix protein 0.021
Lmx1b LIM homeobox transcription factor 1 beta 0.021
Apc2 adenomatosis polyposis coli 2 0.021
Pramel7 preferentially expressed antigen in melanoma like 7 0.021
Foxj1 forkhead box J1 0.021
Ear4 eosinophil-associated, ribonuclease A family, member 4 0.021
Creld2 cysteine-rich with EGF-like domains 2 0.021
Gm996 predicted gene 996 0.021
Htr6 5-hydroxytryptamine (serotonin) receptor 6 0.021
Pde6a phosphodiesterase 6A, cGMP-specific, rod, alpha 0.021
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ADORA2A adenosine A2a receptor 0.036
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.033
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.029
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.014
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Rattus norvegicus
Name Description Probability Func Analog Organism
Syn1 synapsin I 0.070
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.016
Map6 microtubule-associated protein 6 0.015
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism