IMP
Process View
The network for 'positive regulation of interleukin 8 production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of interleukin 8 production
Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.998 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.908 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.654 | |
| Casp1 | caspase 1 | 0.459 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.399 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.367 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.355 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.328 | |
| Casp8 | caspase 8 | 0.289 | |
| Aim2 | absent in melanoma 2 | 0.266 | |
| Ms4a3 | membrane-spanning 4-domains, subfamily A, member 3 | 0.264 | |
| Wnt10b | wingless related MMTV integration site 10b | 0.241 | |
| Vax1 | ventral anterior homeobox containing gene 1 | 0.225 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.209 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.169 | |
| Ly96 | lymphocyte antigen 96 | 0.165 | |
| Plaur | plasminogen activator, urokinase receptor | 0.161 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.160 | |
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.160 | |
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.150 | |
| Traf3 | TNF receptor-associated factor 3 | 0.148 | |
| Gbp5 | guanylate binding protein 5 | 0.144 | |
| Treml1 | triggering receptor expressed on myeloid cells-like 1 | 0.139 | |
| Wnt2b | wingless related MMTV integration site 2b | 0.139 | |
| Ret | ret proto-oncogene | 0.134 | |
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.134 | |
| Porcn | porcupine homolog (Drosophila) | 0.134 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.126 | |
| Il1r1 | interleukin 1 receptor, type I | 0.123 | |
| Fzd10 | frizzled homolog 10 (Drosophila) | 0.120 | |
| Lhx1 | LIM homeobox protein 1 | 0.117 | |
| Klf6 | Kruppel-like factor 6 | 0.111 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.108 | |
| Il1a | interleukin 1 alpha | 0.105 | |
| Fgf18 | fibroblast growth factor 18 | 0.103 | |
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.102 | |
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.100 | |
| Irak4 | interleukin-1 receptor-associated kinase 4 | 0.100 | |
| Itgb2l | integrin beta 2-like | 0.098 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.097 | |
| Tbxa2r | thromboxane A2 receptor | 0.085 | |
| T | brachyury | 0.084 | |
| Nobox | NOBOX oogenesis homeobox | 0.082 | |
| Wnt1 | wingless-related MMTV integration site 1 | 0.081 | |
| Pou3f1 | POU domain, class 3, transcription factor 1 | 0.080 | |
| Sftpb | surfactant associated protein B | 0.080 | |
| Tnni2 | troponin I, skeletal, fast 2 | 0.079 | |
| Neurog1 | neurogenin 1 | 0.075 | |
| Dlx4 | distal-less homeobox 4 | 0.074 | |
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.074 | |
| Pax8 | paired box gene 8 | 0.073 | |
| Epha1 | Eph receptor A1 | 0.072 | |
| Fut7 | fucosyltransferase 7 | 0.072 | |
| Cd14 | CD14 antigen | 0.071 | |
| Wnt10a | wingless related MMTV integration site 10a | 0.068 | |
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.066 | |
| B3gnt3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | 0.064 | |
| Fhl3 | four and a half LIM domains 3 | 0.063 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.062 | |
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.062 | |
| Kl | klotho | 0.061 | |
| Slc34a2 | solute carrier family 34 (sodium phosphate), member 2 | 0.060 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.060 | |
| Msln | mesothelin | 0.059 | |
| Capn8 | calpain 8 | 0.058 | |
| Aco1 | aconitase 1 | 0.058 | |
| Plscr1 | phospholipid scramblase 1 | 0.058 | |
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.058 | |
| Traf2 | TNF receptor-associated factor 2 | 0.055 | |
| Rspo1 | R-spondin homolog (Xenopus laevis) | 0.055 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.055 | |
| Acan | aggrecan | 0.054 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.054 | |
| Cdx1 | caudal type homeobox 1 | 0.054 | |
| Emp2 | epithelial membrane protein 2 | 0.053 | |
| Scube1 | signal peptide, CUB domain, EGF-like 1 | 0.053 | |
| Tbx2 | T-box 2 | 0.052 | |
| Kcnh3 | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 0.052 | |
| Hoxc9 | homeobox C9 | 0.052 | |
| Lyzl4 | lysozyme-like 4 | 0.050 | |
| Clic3 | chloride intracellular channel 3 | 0.050 | |
| Romo1 | reactive oxygen species modulator 1 | 0.049 | |
| Tnf | tumor necrosis factor | 0.049 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.048 | |
| Ikbkg | inhibitor of kappaB kinase gamma | 0.048 | |
| Lbx2 | ladybird homeobox homolog 2 (Drosophila) | 0.048 | |
| Reck | reversion-inducing-cysteine-rich protein with kazal motifs | 0.047 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.047 | |
| Ppl | periplakin | 0.047 | |
| Mmp9 | matrix metallopeptidase 9 | 0.047 | |
| Cdca3 | cell division cycle associated 3 | 0.045 | |
| Itch | itchy, E3 ubiquitin protein ligase | 0.045 | |
| Inhbb | inhibin beta-B | 0.045 | |
| Slc16a8 | solute carrier family 16 (monocarboxylic acid transporters), member 8 | 0.044 | |
| Ngp | neutrophilic granule protein | 0.044 | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.044 | |
| Tlr2 | toll-like receptor 2 | 0.044 | |
| Lrg1 | leucine-rich alpha-2-glycoprotein 1 | 0.044 | |
| Ccl24 | chemokine (C-C motif) ligand 24 | 0.044 | |
| Gpr132 | G protein-coupled receptor 132 | 0.043 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 1.000 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.995 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.932 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.783 | |
| IL1R1 | interleukin 1 receptor, type I | 0.607 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.604 | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.593 | |
| TLR4 | toll-like receptor 4 | 0.576 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.575 | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.453 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.374 | |
| PLAU | plasminogen activator, urokinase | 0.370 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.314 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.299 | |
| TRAF3 | TNF receptor-associated factor 3 | 0.294 | |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.258 | |
| FGA | fibrinogen alpha chain | 0.254 | |
| TRAF2 | TNF receptor-associated factor 2 | 0.206 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.200 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.195 | |
| CRP | C-reactive protein, pentraxin-related | 0.182 | |
| TLR2 | toll-like receptor 2 | 0.161 | |
| PLAT | plasminogen activator, tissue | 0.136 | |
| MEFV | Mediterranean fever | 0.126 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.126 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.121 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.117 | |
| LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.098 | |
| CARD11 | caspase recruitment domain family, member 11 | 0.095 | |
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.092 | |
| TRADD | TNFRSF1A-associated via death domain | 0.089 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.080 | |
| LY96 | lymphocyte antigen 96 | 0.080 | |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.077 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.076 | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.073 | |
| TXN | thioredoxin | 0.073 | |
| C9orf89 | chromosome 9 open reading frame 89 | 0.070 | |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.069 | |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.067 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.066 | |
| TSC22D4 | TSC22 domain family, member 4 | 0.065 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.065 | |
| ORM1 | orosomucoid 1 | 0.061 | |
| MARCO | macrophage receptor with collagenous structure | 0.060 | |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.060 | |
| IL1R2 | interleukin 1 receptor, type II | 0.057 | |
| MPO | myeloperoxidase | 0.055 | |
| PYDC2 | pyrin domain containing 2 | 0.053 | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.053 | |
| IRF7 | interferon regulatory factor 7 | 0.049 | |
| SPOP | speckle-type POZ protein | 0.048 | |
| TANK | TRAF family member-associated NFKB activator | 0.048 | |
| ELANE | elastase, neutrophil expressed | 0.047 | |
| IL1RN | interleukin 1 receptor antagonist | 0.046 | |
| CD14 | CD14 molecule | 0.044 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.043 | |
| CAMP | cathelicidin antimicrobial peptide | 0.043 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.042 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.041 | |
| ATF3 | activating transcription factor 3 | 0.040 | |
| HDAC7 | histone deacetylase 7 | 0.039 | |
| RRBP1 | ribosome binding protein 1 homolog 180kDa (dog) | 0.039 | |
| DBP | D site of albumin promoter (albumin D-box) binding protein | 0.038 | |
| TMEM173 | transmembrane protein 173 | 0.038 | |
| FCAR | Fc fragment of IgA, receptor for | 0.038 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.037 | |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.035 | |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.033 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.033 | |
| IL8 | interleukin 8 | 0.033 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.032 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.032 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.032 | |
| TLR1 | toll-like receptor 1 | 0.031 | |
| IL1RAP | interleukin 1 receptor accessory protein | 0.031 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.031 | |
| CTSG | cathepsin G | 0.031 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.030 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.030 | |
| TLR7 | toll-like receptor 7 | 0.030 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.030 | |
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.030 | |
| RETN | resistin | 0.029 | |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.029 | |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.027 | |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.027 | |
| TRIM38 | tripartite motif containing 38 | 0.027 | |
| AZU1 | azurocidin 1 | 0.026 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.026 | |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.026 | |
| CLEC4G | C-type lectin domain family 4, member G | 0.026 | |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.026 | |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.025 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.024 | |
| NOG | noggin | 0.024 | |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | 0.024 | |
| S100A12 | S100 calcium binding protein A12 | 0.023 | |
| STAP2 | signal transducing adaptor family member 2 | 0.023 | |
| SOD1 | superoxide dismutase 1, soluble | 0.022 |