IMP
Process View
The network for 'positive regulation of glutamate secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of glutamate secretion
Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 1.000 | |
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.899 | |
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.338 | |
| Grm1 | glutamate receptor, metabotropic 1 | 0.320 | |
| Drd2 | dopamine receptor D2 | 0.171 | |
| Gnrh1 | gonadotropin releasing hormone 1 | 0.162 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.137 | |
| Atxn1 | ataxin 1 | 0.126 | |
| Gabbr2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.124 | |
| Plcb1 | phospholipase C, beta 1 | 0.122 | |
| Plcg1 | phospholipase C, gamma 1 | 0.119 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.119 | |
| Nf1 | neurofibromatosis 1 | 0.115 | |
| Dnm1 | dynamin 1 | 0.113 | |
| P2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.112 | |
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.093 | |
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.089 | |
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.084 | |
| App | amyloid beta (A4) precursor protein | 0.080 | |
| Ptgir | prostaglandin I receptor (IP) | 0.077 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.070 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.068 | |
| Gata1 | GATA binding protein 1 | 0.065 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.062 | |
| Epas1 | endothelial PAS domain protein 1 | 0.058 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.056 | |
| P2rx3 | purinergic receptor P2X, ligand-gated ion channel, 3 | 0.055 | |
| Nt5e | 5' nucleotidase, ecto | 0.052 | |
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.051 | |
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.049 | |
| Prkcc | protein kinase C, gamma | 0.047 | |
| Kif1b | kinesin family member 1B | 0.045 | |
| Cit | citron | 0.040 | |
| Crmp1 | collapsin response mediator protein 1 | 0.037 | |
| Apln | apelin | 0.037 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.036 | |
| Tmed8 | transmembrane emp24 domain containing 8 | 0.035 | |
| Trpm5 | transient receptor potential cation channel, subfamily M, member 5 | 0.035 | |
| Braf | Braf transforming gene | 0.034 | |
| Inpp4a | inositol polyphosphate-4-phosphatase, type I | 0.034 | |
| Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.033 | |
| Shank3 | SH3/ankyrin domain gene 3 | 0.030 | |
| Snx13 | sorting nexin 13 | 0.030 | |
| Spert | spermatid associated | 0.030 | |
| Mtap2 | microtubule-associated protein 2 | 0.028 | |
| Prkce | protein kinase C, epsilon | 0.028 | |
| Sntb1 | syntrophin, basic 1 | 0.028 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.028 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.028 | |
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.027 | |
| Fut7 | fucosyltransferase 7 | 0.027 | |
| Egfr | epidermal growth factor receptor | 0.027 | |
| Tspyl1 | testis-specific protein, Y-encoded-like 1 | 0.026 | |
| Rasgrp1 | RAS guanyl releasing protein 1 | 0.026 | |
| Sstr3 | somatostatin receptor 3 | 0.026 | |
| Klhl24 | kelch-like 24 (Drosophila) | 0.025 | |
| Socs5 | suppressor of cytokine signaling 5 | 0.024 | |
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.024 | |
| Plxna1 | plexin A1 | 0.024 | |
| Gjc2 | gap junction protein, gamma 2 | 0.024 | |
| Sdc3 | syndecan 3 | 0.023 | |
| Prkcb | protein kinase C, beta | 0.023 | |
| 1810065E05Rik | RIKEN cDNA 1810065E05 gene | 0.023 | |
| Il6st | interleukin 6 signal transducer | 0.022 | |
| Apoe | apolipoprotein E | 0.022 | |
| Cela2a | chymotrypsin-like elastase family, member 2A | 0.022 | |
| Hif3a | hypoxia inducible factor 3, alpha subunit | 0.022 | |
| Vav2 | vav 2 oncogene | 0.022 | |
| Clock | circadian locomotor output cycles kaput | 0.021 | |
| Phf1 | PHD finger protein 1 | 0.021 | |
| Slc39a5 | solute carrier family 39 (metal ion transporter), member 5 | 0.021 | |
| Grin2d | glutamate receptor, ionotropic, NMDA2D (epsilon 4) | 0.021 | |
| Adam23 | a disintegrin and metallopeptidase domain 23 | 0.021 | |
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.021 | |
| Sstr2 | somatostatin receptor 2 | 0.021 | |
| Aatk | apoptosis-associated tyrosine kinase | 0.020 | |
| Mtl5 | metallothionein-like 5, testis-specific (tesmin) | 0.020 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.020 | |
| Dnajb8 | DnaJ (Hsp40) homolog, subfamily B, member 8 | 0.020 | |
| Lyl1 | lymphoblastomic leukemia 1 | 0.020 | |
| Arhgef2 | rho/rac guanine nucleotide exchange factor (GEF) 2 | 0.019 | |
| a | nonagouti | 0.019 | |
| Gcgr | glucagon receptor | 0.019 | |
| Cel | carboxyl ester lipase | 0.019 | |
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.018 | |
| Tapbp | TAP binding protein | 0.018 | |
| Cd38 | CD38 antigen | 0.018 | |
| Pax4 | paired box gene 4 | 0.018 | |
| Il10rb | interleukin 10 receptor, beta | 0.018 | |
| Arc | activity regulated cytoskeletal-associated protein | 0.018 | |
| Shank2 | SH3/ankyrin domain gene 2 | 0.018 | |
| Il10ra | interleukin 10 receptor, alpha | 0.018 | |
| Mageb3 | melanoma antigen, family B, 3 | 0.018 | |
| Atp8a1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.017 | |
| Kcnh3 | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 0.017 | |
| Tlr9 | toll-like receptor 9 | 0.017 | |
| Odf3 | outer dense fiber of sperm tails 3 | 0.017 | |
| Atp6v1e2 | ATPase, H+ transporting, lysosomal V1 subunit E2 | 0.017 | |
| Pklr | pyruvate kinase liver and red blood cell | 0.017 | |
| Nags | N-acetylglutamate synthase | 0.017 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.282 | |
| Kcnq3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.266 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.117 | |
| Kcnq2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.113 | |
| Grin1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 0.102 | |
| Oprm1 | opioid receptor, mu 1 | 0.082 | |
| Celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | 0.076 | |
| Fev | FEV (ETS oncogene family) | 0.053 | |
| Igf2 | insulin-like growth factor 2 | 0.048 | |
| St8sia3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 0.046 | |
| Rap2ip | Rap2 interacting protein | 0.046 | |
| Nfasc | neurofascin | 0.038 | |
| Vcsa1 | variable coding sequence A1 | 0.035 | |
| Cit | citron | 0.035 | |
| Shox2 | short stature homeobox 2 | 0.032 | |
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.032 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.031 | |
| Gabbr1 | gamma-aminobutyric acid (GABA) B receptor 1 | 0.031 | |
| Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.031 | |
| Uncx | UNC homeobox | 0.030 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.028 | |
| Syn1 | synapsin I | 0.028 | |
| Syngap1 | synaptic Ras GTPase activating protein 1 homolog (rat) | 0.027 | |
| Chrm3 | cholinergic receptor, muscarinic 3 | 0.026 | |
| Gfap | glial fibrillary acidic protein | 0.026 | |
| Marcks | myristoylated alanine rich protein kinase C substrate | 0.025 | |
| Trhr | thyrotropin releasing hormone receptor | 0.025 | |
| Grin3a | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | 0.024 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.024 | |
| Chrnb4 | cholinergic receptor, nicotinic, beta 4 | 0.022 | |
| Nmbr | neuromedin B receptor | 0.022 | |
| Nptxr | neuronal pentraxin receptor | 0.021 | |
| Htr3a | 5-hydroxytryptamine (serotonin) receptor 3a | 0.021 | |
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.020 | |
| Cntfr | ciliary neurotrophic factor receptor | 0.020 | |
| Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | 0.020 | |
| Pgbd5 | piggyBac transposable element derived 5 | 0.018 | |
| Tubb3 | tubulin, beta 3 | 0.018 | |
| Strn | striatin, calmodulin binding protein | 0.017 | |
| Gpr6 | G protein-coupled receptor 6 | 0.017 | |
| Gng7 | guanine nucleotide binding protein (G protein), gamma 7 | 0.017 | |
| Adora2a | adenosine A2a receptor | 0.016 | |
| Adora1 | adenosine A1 receptor | 0.016 | |
| Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.016 | |
| Pcsk4 | proprotein convertase subtilisin/kexin type 4 | 0.016 | |
| Prp2 | proline rich protein 2 | 0.015 | |
| RGD1304952 | similar to RIKEN cDNA C530028O21 gene | 0.015 | |
| Cyp4a8 | cytochrome P450, family 4, subfamily a, polypeptide 8 | 0.015 | |
| Atp2b3 | ATPase, Ca++ transporting, plasma membrane 3 | 0.015 | |
| Adrbk2 | adrenergic, beta, receptor kinase 2 | 0.015 | |
| Kalrn | kalirin, RhoGEF kinase | 0.015 | |
| Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.015 | |
| Rxrg | retinoid X receptor gamma | 0.015 | |
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.014 | |
| Gabrg1 | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 0.014 | |
| Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.014 | |
| Mylk2 | myosin light chain kinase 2 | 0.014 | |
| Ar | androgen receptor | 0.013 | |
| P2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.013 | |
| Erbb4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.013 | |
| Atxn1 | ataxin 1 | 0.013 | |
| Hrh2 | histamine receptor H 2 | 0.013 | |
| Egr4 | early growth response 4 | 0.013 | |
| Pnoc | prepronociceptin | 0.012 | |
| Irs3 | insulin receptor substrate 3 | 0.012 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.012 | |
| Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | 0.012 | |
| Hes3 | hairy and enhancer of split 3 (Drosophila) | 0.011 | |
| Gprin1 | G protein-regulated inducer of neurite outgrowth 1 | 0.011 | |
| Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.011 | |
| Calb2 | calbindin 2 | 0.011 | |
| Fam83f | family with sequence similarity 83, member F | 0.011 | |
| Arpp21 | cAMP-regulated phosphoprotein 21 | 0.011 | |
| Cd40lg | CD40 ligand | 0.011 | |
| Igfals | insulin-like growth factor binding protein, acid labile subunit | 0.011 | |
| Adora3 | adenosine A3 receptor | 0.011 | |
| Pemt | phosphatidylethanolamine N-methyltransferase | 0.010 | |
| LOC100360919 | Immunoglobulin lambda-like polypeptide 1-like | 0.010 | |
| Olr1356 | olfactory receptor 1356 | 0.010 | |
| Gck | glucokinase | 0.010 | |
| Slc18a3 | solute carrier family 18 (vesicular acetylcholine), member 3 | 0.010 |