Process View
The network for 'response to parathyroid hormone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Mef2d | myocyte enhancer factor 2D | 0.975 | |
Pax2 | paired box gene 2 | 0.939 | |
Fgf8 | fibroblast growth factor 8 | 0.839 | |
Nodal | nodal | 0.733 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.643 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.633 | |
T | brachyury | 0.576 | |
Kl | klotho | 0.572 | |
Wnt1 | wingless-related MMTV integration site 1 | 0.481 | |
Lhx1 | LIM homeobox protein 1 | 0.442 | |
Adrb1 | adrenergic receptor, beta 1 | 0.390 | |
Gdnf | glial cell line derived neurotrophic factor | 0.379 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.366 | |
Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.345 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.313 | |
Fgf15 | fibroblast growth factor 15 | 0.264 | |
Tbx1 | T-box 1 | 0.253 | |
Wnt6 | wingless-related MMTV integration site 6 | 0.244 | |
Wnt10b | wingless related MMTV integration site 10b | 0.230 | |
Efna4 | ephrin A4 | 0.186 | |
Porcn | porcupine homolog (Drosophila) | 0.172 | |
Lyzl4 | lysozyme-like 4 | 0.170 | |
Shh | sonic hedgehog | 0.162 | |
Fgf18 | fibroblast growth factor 18 | 0.160 | |
Fzd8 | frizzled homolog 8 (Drosophila) | 0.139 | |
Rarb | retinoic acid receptor, beta | 0.139 | |
Bmp7 | bone morphogenetic protein 7 | 0.138 | |
Mef2a | myocyte enhancer factor 2A | 0.133 | |
Amhr2 | anti-Mullerian hormone type 2 receptor | 0.129 | |
Pnpla2 | patatin-like phospholipase domain containing 2 | 0.127 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.122 | |
Gata6 | GATA binding protein 6 | 0.118 | |
Hoxa13 | homeobox A13 | 0.117 | |
Rarg | retinoic acid receptor, gamma | 0.114 | |
Fgf5 | fibroblast growth factor 5 | 0.106 | |
Irx4 | Iroquois related homeobox 4 (Drosophila) | 0.106 | |
Gata4 | GATA binding protein 4 | 0.104 | |
Npas1 | neuronal PAS domain protein 1 | 0.104 | |
Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.100 | |
Hdac5 | histone deacetylase 5 | 0.098 | |
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.098 | |
Vax1 | ventral anterior homeobox containing gene 1 | 0.097 | |
Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.089 | |
Cdx1 | caudal type homeobox 1 | 0.088 | |
Hoxc9 | homeobox C9 | 0.088 | |
Adra2a | adrenergic receptor, alpha 2a | 0.087 | |
Zfp771 | zinc finger protein 771 | 0.085 | |
Neurog1 | neurogenin 1 | 0.081 | |
Emid2 | EMI domain containing 2 | 0.081 | |
Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.075 | |
Foxc1 | forkhead box C1 | 0.075 | |
Krtdap | keratinocyte differentiation associated protein | 0.075 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.073 | |
Barx2 | BarH-like homeobox 2 | 0.071 | |
Col22a1 | collagen, type XXII, alpha 1 | 0.070 | |
Pou3f1 | POU domain, class 3, transcription factor 1 | 0.069 | |
Ntf3 | neurotrophin 3 | 0.068 | |
Lhx5 | LIM homeobox protein 5 | 0.068 | |
Tnni2 | troponin I, skeletal, fast 2 | 0.068 | |
Lmx1b | LIM homeobox transcription factor 1 beta | 0.068 | |
Krt15 | keratin 15 | 0.067 | |
Fto | fat mass and obesity associated | 0.062 | |
Zfp651 | zinc finger protein 651 | 0.061 | |
Grb10 | growth factor receptor bound protein 10 | 0.061 | |
Nrtn | neurturin | 0.059 | |
Pou3f3 | POU domain, class 3, transcription factor 3 | 0.058 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.057 | |
Hoxd11 | homeobox D11 | 0.056 | |
Amh | anti-Mullerian hormone | 0.056 | |
Sim2 | single-minded homolog 2 (Drosophila) | 0.055 | |
Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | 0.055 | |
Acvr2b | activin receptor IIB | 0.054 | |
Clic3 | chloride intracellular channel 3 | 0.054 | |
Scube1 | signal peptide, CUB domain, EGF-like 1 | 0.054 | |
Gpr50 | G-protein-coupled receptor 50 | 0.053 | |
Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.053 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.052 | |
Angpt4 | angiopoietin 4 | 0.052 | |
Prkar2b | protein kinase, cAMP dependent regulatory, type II beta | 0.052 | |
Hoxd9 | homeobox D9 | 0.051 | |
Twist2 | twist homolog 2 (Drosophila) | 0.051 | |
Ret | ret proto-oncogene | 0.050 | |
H1fx | H1 histone family, member X | 0.050 | |
Nog | noggin | 0.050 | |
Fgf3 | fibroblast growth factor 3 | 0.049 | |
Tnfrsf8 | tumor necrosis factor receptor superfamily, member 8 | 0.049 | |
Ephb2 | Eph receptor B2 | 0.049 | |
Slc27a3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.049 | |
Mgrn1 | mahogunin, ring finger 1 | 0.048 | |
Rspo1 | R-spondin homolog (Xenopus laevis) | 0.047 | |
Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.046 | |
Hsd11b2 | hydroxysteroid 11-beta dehydrogenase 2 | 0.046 | |
Sox1 | SRY-box containing gene 1 | 0.046 | |
Igf2 | insulin-like growth factor 2 | 0.046 | |
Trp73 | transformation related protein 73 | 0.045 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.045 | |
Drd2 | dopamine receptor D2 | 0.045 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.044 | |
Socs1 | suppressor of cytokine signaling 1 | 0.044 | |
Eif4ebp2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.043 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
HDAC4 | histone deacetylase 4 | 0.967 | |
MEF2A | myocyte enhancer factor 2A | 0.857 | |
GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.644 | |
ARRB1 | arrestin, beta 1 | 0.639 | |
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.560 | |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.185 | |
MEF2C | myocyte enhancer factor 2C | 0.162 | |
AKIP1 | A kinase (PRKA) interacting protein 1 | 0.107 | |
HDAC9 | histone deacetylase 9 | 0.103 | |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.102 | |
NCF2 | neutrophil cytosolic factor 2 | 0.075 | |
MAPK10 | mitogen-activated protein kinase 10 | 0.070 | |
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.066 | |
EP300 | E1A binding protein p300 | 0.058 | |
FLNA | filamin A, alpha | 0.055 | |
MIF4GD | MIF4G domain containing | 0.054 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.045 | |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.043 | |
CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.040 | |
NCF1 | neutrophil cytosolic factor 1 | 0.038 | |
RYR2 | ryanodine receptor 2 (cardiac) | 0.036 | |
MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.029 | |
NUCB1 | nucleobindin 1 | 0.029 | |
GNMT | glycine N-methyltransferase | 0.024 | |
DCTN2 | dynactin 2 (p50) | 0.023 | |
HDAC5 | histone deacetylase 5 | 0.023 | |
ZMYM3 | zinc finger, MYM-type 3 | 0.023 | |
CFL1 | cofilin 1 (non-muscle) | 0.021 | |
CYLD | cylindromatosis (turban tumor syndrome) | 0.021 | |
HIPK2 | homeodomain interacting protein kinase 2 | 0.020 | |
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.019 | |
TUBA1A | tubulin, alpha 1a | 0.019 | |
GRIP1 | glutamate receptor interacting protein 1 | 0.018 | |
WASF2 | WAS protein family, member 2 | 0.017 | |
MYLK2 | myosin light chain kinase 2 | 0.017 | |
SORBS3 | sorbin and SH3 domain containing 3 | 0.015 | |
SIRT2 | sirtuin 2 | 0.015 | |
GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.015 | |
GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.015 | |
AES | amino-terminal enhancer of split | 0.015 | |
PRKCA | protein kinase C, alpha | 0.015 | |
MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.014 | |
PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.014 | |
CORO1C | coronin, actin binding protein, 1C | 0.014 | |
MECP2 | methyl CpG binding protein 2 (Rett syndrome) | 0.013 | |
NCOR1 | nuclear receptor corepressor 1 | 0.013 | |
ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.013 | |
GNAS | GNAS complex locus | 0.013 | |
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.013 | |
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.013 | |
EIF5 | eukaryotic translation initiation factor 5 | 0.012 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.012 | |
RAP1B | RAP1B, member of RAS oncogene family | 0.012 | |
MAPK7 | mitogen-activated protein kinase 7 | 0.012 | |
PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.012 | |
NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | 0.011 | |
NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.011 | |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.011 | |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.011 | |
STAT5A | signal transducer and activator of transcription 5A | 0.010 | |
ZFAND5 | zinc finger, AN1-type domain 5 | 0.010 | |
ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.010 | |
MPRIP | myosin phosphatase Rho interacting protein | 0.010 | |
NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | 0.010 | |
PPT1 | palmitoyl-protein thioesterase 1 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Rps10 | ribosomal protein S10 | 0.027 | |
Rps16 | ribosomal protein S16 | 0.026 | |
Rpl18a | ribosomal protein L18A | 0.026 | |
Rps26 | ribosomal protein S26 | 0.025 | |
Uba52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.023 | |
LOC100360491 | 60S ribosomal protein L13-like | 0.022 | |
Fau | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.022 | |
Rps15 | ribosomal protein S15 | 0.022 | |
Rplp0 | ribosomal protein, large, P0 | 0.021 | |
Rpl15 | ribosomal protein L15 | 0.020 | |
Rpsa | ribosomal protein SA | 0.020 | |
Rpl10a | ribosomal protein L10A | 0.019 | |
Rps21 | ribosomal protein S21 | 0.018 | |
Rps17 | ribosomal protein S17 | 0.017 | |
Rps5 | ribosomal protein S5 | 0.017 | |
Rpl27a | ribosomal protein L27a | 0.017 | |
Rpl18 | ribosomal protein L18 | 0.016 | |
Rps19 | ribosomal protein S19 | 0.016 | |
Rpl19 | ribosomal protein L19 | 0.014 | |
Ppib | peptidylprolyl isomerase B | 0.014 | |
LOC100362298 | ribosomal protein S18-like | 0.014 | |
Park7 | Parkinson disease (autosomal recessive, early onset) 7 | 0.014 | |
LOC499782 | similar to 60S ribosomal protein L12 | 0.014 | |
Rps9 | ribosomal protein S9 | 0.013 | |
Aprt | adenine phosphoribosyl transferase | 0.013 | |
Rpl29 | ribosomal protein L29 | 0.013 | |
Mrpl54 | mitochondrial ribosomal protein L54 | 0.013 | |
Rps3 | ribosomal protein S3 | 0.012 | |
Ndufc1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 | 0.012 | |
Rpl35 | ribosomal protein L35 | 0.012 | |
LOC100188932 | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 | 0.012 | |
Rps28 | ribosomal protein S28 | 0.011 | |
Rps27a | ribosomal protein S27a | 0.011 | |
Rpl28 | ribosomal protein L28 | 0.011 | |
Rps7 | ribosomal protein S7 | 0.010 | |
Tceb2 | transcription elongation factor B (SIII), polypeptide 2 | 0.010 | |
Rpl23a | ribosomal protein L23a | 0.010 | |
Rps14 | ribosomal protein S14 | 0.010 | |
Rpl17 | ribosomal protein L17 | 0.010 | |
Atp5o | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit | 0.010 | |
Cox5b | cytochrome c oxidase subunit Vb | 0.010 | |
Myl6l | myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like | 0.010 |