The network for 'negative regulation of retinal cell programmed cell death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of retinal cell programmed cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.

Mus musculus
Name Description Probability Func Analog Organism
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.998
Bak1 BCL2-antagonist/killer 1 0.571
Bax BCL2-associated X protein 0.560
Trp53 transformation related protein 53 0.559
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.268
Bcl2 B-cell leukemia/lymphoma 2 0.237
Kit kit oncogene 0.119
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.104
Wt1 Wilms tumor 1 homolog 0.061
Prmt1 protein arginine N-methyltransferase 1 0.044
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.043
Pten phosphatase and tensin homolog 0.042
Cd19 CD19 antigen 0.032
Lyst lysosomal trafficking regulator 0.030
Id4 inhibitor of DNA binding 4 0.027
Rxra retinoid X receptor alpha 0.027
Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 0.026
Bbc3 BCL2 binding component 3 0.026
Bid BH3 interacting domain death agonist 0.025
Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 0.025
Pax2 paired box gene 2 0.025
Otx2 orthodenticle homolog 2 (Drosophila) 0.025
Notch2 Notch gene homolog 2 (Drosophila) 0.024
Ikzf3 IKAROS family zinc finger 3 0.024
Cct5 chaperonin containing Tcp1, subunit 5 (epsilon) 0.022
Gdnf glial cell line derived neurotrophic factor 0.022
Epn1 epsin 1 0.020
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.020
Unc5c unc-5 homolog C (C. elegans) 0.019
Huwe1 HECT, UBA and WWE domain containing 1 0.019
Nphs2 nephrosis 2 homolog, podocin (human) 0.018
Ehd3 EH-domain containing 3 0.017
Ehd4 EH-domain containing 4 0.016
Pxn paxillin 0.015
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.015
Pbx1 pre B-cell leukemia transcription factor 1 0.015
Prph2 peripherin 2 0.015
Ret ret proto-oncogene 0.015
Fgfr2 fibroblast growth factor receptor 2 0.015
Pax6 paired box gene 6 0.014
Igh immunoglobulin heavy chain complex 0.014
Btg1 B-cell translocation gene 1, anti-proliferative 0.013
Ppan peter pan homolog (Drosophila) 0.013
Nme1 non-metastatic cells 1, protein (NM23A) expressed in 0.012
Igfbpl1 insulin-like growth factor binding protein-like 1 0.012
Klf6 Kruppel-like factor 6 0.011
Rara retinoic acid receptor, alpha 0.011
Sox8 SRY-box containing gene 8 0.011
Ncoa3 nuclear receptor coactivator 3 0.011
Ntn1 netrin 1 0.011
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.011
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.011
Insm1 insulinoma-associated 1 0.011
Emx1 empty spiracles homolog 1 (Drosophila) 0.011
Sox21 SRY-box containing gene 21 0.011
Emx2 empty spiracles homolog 2 (Drosophila) 0.011
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.010
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
otx2 orthodenticle homolog 2 0.201
msxe muscle segment homeobox E 0.163
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.113
bhlhe22 basic helix-loop-helix family, member e22 0.074
efna5a ephrin A5a 0.065
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.063
pax6b paired box gene 6b 0.052
rx3 retinal homeobox gene 3 0.044
aanat2 arylalkylamine N-acetyltransferase 0.044
six3b sine oculis homeobox homolog 3b 0.043
barhl2 BarH-like 2 0.038
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.034
rho rhodopsin 0.030
rx2 retinal homeobox gene 2 0.029
pax6a paired box gene 6a 0.028
otx1b orthodenticle homolog 1b 0.027
rxrga retinoid x receptor, gamma a 0.026
dbx1b developing brain homeobox 1b 0.025
fezf2 FEZ family zinc finger 2 0.025
rlbp1a retinaldehyde binding protein 1a 0.024
tshb thyroid stimulating hormone, beta subunit 0.024
irx7 iroquois homeobox protein 7 0.024
neurod neurogenic differentiation 0.020
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.019
foxp2 forkhead box P2 0.018
nkx2.1a NK2 homeobox 1a 0.018
pax5 paired box gene 5 0.017
six3a sine oculis homeobox homolog 3a 0.016
flh floating head 0.015
vsx1 visual system homeobox 1 homolog, chx10-like 0.015
neurog1 neurogenin 1 0.015
neurod4 neurogenic differentiation 4 0.014
rcv1 recoverin 0.014
tbx6 T-box gene 6 0.013
prom1b prominin 1 b 0.013
guk1 guanylate kinase 1 0.013
arr3a arrestin 3a, retinal (X-arrestin) 0.012
ephb3a eph receptor B3a 0.012
lhx5 LIM homeobox 5 0.012
dla deltaA 0.012
atoh7 atonal homolog 7 0.011
dbx1a developing brain homeobox 1a 0.010
dmbx1a diencephalon/mesencephalon homeobox 1a 0.010
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
trp transient receptor potential 0.864
ninaE neither inactivation nor afterpotential E 0.802
inaD inactivation no afterpotential D 0.496
trpl trp-like 0.355
Arr2 Arrestin 2 0.293
G-oalpha47A G protein oalpha 47A 0.233
Galpha49B G protein alpha49B 0.210
CdsA CDP diglyceride synthetase 0.208
ninaA neither inactivation nor afterpotential A 0.118
norpA no receptor potential A 0.113
ninaC neither inactivation nor afterpotential C 0.097
inaC inactivation no afterpotential C 0.075
rl rolled 0.058
spi spitz 0.057
rdgA retinal degeneration A 0.055
Tak1 TGF-beta activated kinase 1 0.036
sty sprouty 0.033
emc extra macrochaetae 0.031
rdgB retinal degeneration B 0.030
cno canoe 0.029
rpr reaper 0.029
edl ETS-domain lacking 0.025
Mad Mothers against dpp 0.021
rdgC retinal degeneration C 0.020
wisp wispy 0.020
crb crumbs 0.019
shn schnurri 0.018
Stat92E Signal-transducer and activator of transcription protein at 92E 0.018
Rh3 Rhodopsin 3 0.018
gish gilgamesh 0.018
gl glass 0.017
Mtl Mig-2-like 0.017
ttk tramtrack 0.017
sina seven in absentia 0.017
Rh5 Rhodopsin 5 0.016
Rh6 Rhodopsin 6 0.015
phl pole hole 0.015
Dab Disabled 0.015
Tl Toll 0.014
sev sevenless 0.014
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.014
sbb scribbler 0.014
tadr torn and diminished rhabdomeres 0.014
myoglianin CG1838 gene product from transcript CG1838-RD 0.014
chp chaoptic 0.013
Ggamma1 G protein gamma 1 0.012
Jra Jun-related antigen 0.012
t tan 0.012
elav embryonic lethal abnormal vision 0.012
bsk basket 0.012
santa-maria scavenger receptor acting in neural tissue and majority of rhodopsin is absent 0.012
shg shotgun 0.012
Gug Grunge 0.012
klar klarsicht 0.011
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.010
inaF-D CG42563 gene product from transcript CG42563-RB 0.010
par-1 CG8201 gene product from transcript CG8201-RA 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism