The network for 'regulation of microtubule depolymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of microtubule depolymerization

Any process that modulates the frequency, rate or extent of microtubule depolymerization.

Mus musculus
Name Description Probability Func Analog Organism
Ccnb1 cyclin B1 0.988
Cdk1 cyclin-dependent kinase 1 0.968
Ccna2 cyclin A2 0.914
Prc1 protein regulator of cytokinesis 1 0.884
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.856
Kif20a kinesin family member 20A 0.818
Ccnb2 cyclin B2 0.776
Anln anillin, actin binding protein 0.745
Birc5 baculoviral IAP repeat-containing 5 0.731
Racgap1 Rac GTPase-activating protein 1 0.705
Bdnf brain derived neurotrophic factor 0.660
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.635
Dcx doublecortin 0.617
Dclk1 doublecortin-like kinase 1 0.614
Plk1 polo-like kinase 1 (Drosophila) 0.590
Kif22 kinesin family member 22 0.566
Kif23 kinesin family member 23 0.514
Kif11 kinesin family member 11 0.460
Mki67 antigen identified by monoclonal antibody Ki 67 0.351
Clasp1 CLIP associating protein 1 0.327
Top2a topoisomerase (DNA) II alpha 0.322
Kif2c kinesin family member 2C 0.286
Trim63 tripartite motif-containing 63 0.282
Aurkb aurora kinase B 0.278
Ckap2 cytoskeleton associated protein 2 0.260
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.250
Kif4 kinesin family member 4 0.250
Macf1 microtubule-actin crosslinking factor 1 0.246
C330027C09Rik RIKEN cDNA C330027C09 gene 0.242
Cdkn3 cyclin-dependent kinase inhibitor 3 0.220
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.190
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.187
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.175
Cdca8 cell division cycle associated 8 0.170
Cks2 CDC28 protein kinase regulatory subunit 2 0.160
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.148
Ccdc99 coiled-coil domain containing 99 0.138
Trp63 transformation related protein 63 0.134
Trim55 tripartite motif-containing 55 0.133
Gtse1 G two S phase expressed protein 1 0.133
Lmna lamin A 0.118
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.105
Trp53 transformation related protein 53 0.103
Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.100
Tacc3 transforming, acidic coiled-coil containing protein 3 0.088
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.088
Lmnb1 lamin B1 0.083
Cep55 centrosomal protein 55 0.082
Pou3f4 POU domain, class 3, transcription factor 4 0.079
Smc2 structural maintenance of chromosomes 2 0.077
Ncaph non-SMC condensin I complex, subunit H 0.077
Nuf2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.067
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.062
Aurka aurora kinase A 0.061
Brca1 breast cancer 1 0.060
Gsk3b glycogen synthase kinase 3 beta 0.059
Cdca5 cell division cycle associated 5 0.058
Musk muscle, skeletal, receptor tyrosine kinase 0.058
Smc4 structural maintenance of chromosomes 4 0.057
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.056
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.054
D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, expressed 0.052
Mstn myostatin 0.052
Ube2c ubiquitin-conjugating enzyme E2C 0.052
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.050
H2afx H2A histone family, member X 0.048
Exoc3 exocyst complex component 3 0.048
Cenpf centromere protein F 0.048
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.047
Tbx10 T-box 10 0.046
Tcf21 transcription factor 21 0.046
Fgfbp1 fibroblast growth factor binding protein 1 0.046
Itga3 integrin alpha 3 0.044
Ect2 ect2 oncogene 0.041
Ttk Ttk protein kinase 0.041
Plk4 polo-like kinase 4 (Drosophila) 0.040
Fam64a family with sequence similarity 64, member A 0.039
Spag5 sperm associated antigen 5 0.039
Nusap1 nucleolar and spindle associated protein 1 0.038
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.037
Ids iduronate 2-sulfatase 0.035
Nkx2-1 NK2 homeobox 1 0.035
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.035
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.035
Shc3 src homology 2 domain-containing transforming protein C3 0.033
Pbk PDZ binding kinase 0.033
Diap3 diaphanous homolog 3 (Drosophila) 0.033
Hcrt hypocretin 0.033
Epas1 endothelial PAS domain protein 1 0.032
Gata3 GATA binding protein 3 0.032
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.032
Cenpn centromere protein N 0.032
Smad3 MAD homolog 3 (Drosophila) 0.031
Fam83d family with sequence similarity 83, member D 0.031
Tbx1 T-box 1 0.031
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.031
Plaa phospholipase A2, activating protein 0.029
Iqcb1 IQ calmodulin-binding motif containing 1 0.029
Astn1 astrotactin 1 0.028
Hmgb2 high mobility group box 2 0.028
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.099
zgc:153369 zgc:153369 0.087
kif14 kinesin family member 14 0.074
sass6 spindle assembly 6 homolog (C. elegans) 0.069
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.058
krcp kelch repeat-containing protein 0.057
nfasca neurofascin homolog (chicken) a 0.041
znf711 zinc finger protein 711 0.041
cdc20 cell division cycle 20 homolog 0.039
wdr45 WD repeat domain 45 0.039
isl2a islet2a 0.036
LOC100536090 targeting protein for Xklp2-B-like 0.036
ankhd1 ankyrin repeat and KH domain containing 1 0.033
zgc:110687 zgc:110687 0.032
si:ch211-69g19.2 si:ch211-69g19.2 0.029
birc5a baculoviral IAP repeat-containing 5a 0.027
si:ch211-266i6.3 si:ch211-266i6.3 0.027
si:ch211-197n10.2 si:ch211-197n10.2 0.023
nusap1 nucleolar and spindle associated protein 1 0.023
phox2b paired-like homeobox 2b 0.022
zgc:152925 zgc:152925 0.022
si:ch211-156j22.4 si:ch211-156j22.4 0.022
tacc3 transforming, acidic coiled-coil containing protein 3 0.021
si:dkey-9k8.1 si:dkey-9k8.1 0.021
crhbp corticotropin releasing hormone binding protein 0.021
ccm2 cerebral cavernous malformation 2 0.020
sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.019
im:7136185 im:7136185 0.019
sfswap splicing factor, suppressor of white-apricot homolog (Drosophila) 0.019
hcrtr2 hypocretin (orexin) receptor 2 0.019
ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.018
mtnr1bb melatonin receptor 1B b and melatonin receptor 1B 0.018
gmds GDP-mannose 4,6-dehydratase 0.018
nhsl1b NHS-like 1b 0.018
pik3c3 phosphoinositide-3-kinase, class 3 0.017
plxna3 plexin A3 0.017
zgc:136263 zgc:136263 0.017
cables1 Cdk5 and Abl enzyme substrate 1 0.016
slc45a2 solute carrier family 45, member 2 0.016
cdca8 cell division cycle associated 8 0.016
plxna4 plexin A4 0.016
baxb bcl2-associated X protein, b 0.015
cep55l centrosomal protein 55 like 0.015
ticrr TopBP1-interacting, checkpoint, and replication regulator 0.015
traf4a tnf receptor-associated factor 4a 0.015
ttk ttk protein kinase 0.015
lhx6 LIM homeobox 6 0.014
senp6a SUMO1/sentrin specific peptidase 6a 0.014
yy1b YY1 transcription factor b 0.014
akap8l A kinase (PRKA) anchor protein 8-like 0.014
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.014
kdm5c lysine (K)-specific demethylase 5C 0.014
prok2 prokineticin 2 0.013
cse1l chromosome segregation 1-like (S. cerevisiae) 0.013
sb:cb8 sb:cb8 0.013
krit1 KRIT1, ankyrin repeat containing 0.013
tubg1 tubulin, gamma 1 0.012
cnot1 CCR4-NOT transcription complex, subunit 1 0.012
ankrd13c ankyrin repeat domain 13C 0.012
si:ch211-51m24.3 si:ch211-51m24.3 0.012
foxm1 forkhead box M1 0.012
trim33 tripartite motif-containing 33 0.012
ccnb2 cyclin B2 0.012
birc5b baculoviral IAP repeat-containing 5B 0.012
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.011
prc1b protein regulator of cytokinesis 1b 0.011
flot1 flotillin 1 0.011
si:dkey-235k4.1 si:dkey-235k4.1 0.011
ttc26 tetratricopeptide repeat domain 26 0.011
eno2 enolase 2 0.011
esrrb estrogen-related receptor beta 0.011
st8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.011
stk40 serine/threonine kinase 40 0.011
c20orf14 c20orf14 homolog (H. sapiens) 0.010
her4.5 hairy-related 4.5 0.010
aurka aurora kinase A 0.010
pnx posterior neuron-specific homeobox 0.010
ccna2 cyclin A2 0.010
nadl1.1 neural adhesion molecule L1.1 0.010
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Det Deterin 0.956
dia diaphanous 0.938
vib vibrator 0.909
exo84 CG6095 gene product from transcript CG6095-RA 0.875
CG32038 CG32038 gene product from transcript CG32038-RA 0.827
bru brunelleschi 0.761
pbl pebble 0.734
fws four way stop 0.584
beta-Spec beta Spectrin 0.568
Klp67A Kinesin-like protein at 67A 0.565
sec8 CG2095 gene product from transcript CG2095-RA 0.558
Spc25 CG7242 gene product from transcript CG7242-RA 0.441
Dhc64C Dynein heavy chain 64C 0.311
tef teflon 0.243
gish gilgamesh 0.235
asp abnormal spindle 0.208
Poc1 Proteome of centrioles 1 0.201
rin rasputin 0.172
sti sticky 0.163
egl egalitarian 0.145
ncd non-claret disjunctional 0.139
Lis-1 Lissencephaly-1 0.134
bond james bond 0.121
Sse Separase 0.114
chb chromosome bows 0.105
neb nebbish 0.090
nudE CG8104 gene product from transcript CG8104-RB 0.089
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.085
scra scraps 0.081
jar jaguar 0.075
Rae1 CG9862 gene product from transcript CG9862-RA 0.070
bol boule 0.068
Sas-4 CG10061 gene product from transcript CG10061-RA 0.067
polo CG12306 gene product from transcript CG12306-RA 0.065
Dap160 Dynamin associated protein 160 0.064
aust australin 0.063
gwl greatwall 0.062
tud tudor 0.060
mei-38 meiotic 38 0.059
CG10107 CG10107 gene product from transcript CG10107-RA 0.057
asl asterless 0.057
hts hu li tai shao 0.056
pim pimples 0.056
mtrm matrimony 0.054
CG11329 CG11329 gene product from transcript CG11329-RA 0.050
Rbp9 RNA-binding protein 9 0.047
CG5741 CG5741 gene product from transcript CG5741-RC 0.046
aret arrest 0.044
CG14442 CG14442 gene product from transcript CG14442-RB 0.043
Grip75 CG6176 gene product from transcript CG6176-RA 0.041
pAbp polyA-binding protein 0.039
alpha-Spec alpha Spectrin 0.038
Pak3 CG14895 gene product from transcript CG14895-RA 0.038
foi fear-of-intimacy 0.038
Spc105R Spc105-related 0.037
ana3 anastral spindle 3 0.037
mars CG17064 gene product from transcript CG17064-RB 0.036
spd-2 spindle defective 2 0.034
pav pavarotti 0.033
synj synaptojanin 0.032
borr borealin-related 0.032
flw flapwing 0.030
Sin1 SAPK-interacting protein 1 0.030
Ptp69D Protein tyrosine phosphatase 69D 0.030
larp La related protein 0.029
lkb1 CG9374 gene product from transcript CG9374-RJ 0.028
Trc8 CG2304 gene product from transcript CG2304-RB 0.028
Cog7 CG31040 gene product from transcript CG31040-RA 0.026
mei-P26 CG12218 gene product from transcript CG12218-RA 0.025
elav embryonic lethal abnormal vision 0.025
CG10722 CG10722 gene product from transcript CG10722-RA 0.025
Mrtf Myocardin-related transcription factor 0.025
bel belle 0.024
stj straightjacket 0.024
Ndc80 CG9938 gene product from transcript CG9938-RA 0.024
zpg zero population growth 0.023
sas-6 spindle assembly abnormal 6 0.023
klar klarsicht 0.023
Cct1 CTP:phosphocholine cytidylyltransferase 1 0.023
mfrn mitoferrin 0.022
rictor rapamycin-insensitive companion of Tor 0.022
Cenp-C CG31258 gene product from transcript CG31258-RA 0.021
Slbp Stem-loop binding protein 0.021
CG11750 CG11750 gene product from transcript CG11750-RA 0.021
l(2)dtl lethal-(2)-denticleless 0.021
Psf1 CG9187 gene product from transcript CG9187-RA 0.020
vtd verthandi 0.020
Orc5 Origin recognition complex subunit 5 0.020
CG5491 CG5491 gene product from transcript CG5491-RA 0.019
cdc23 CG2508 gene product from transcript CG2508-RA 0.019
fwd four wheel drive 0.019
Nak Numb-associated kinase 0.019
cnn centrosomin 0.019
CG4558 CG4558 gene product from transcript CG4558-RA 0.019
rux roughex 0.018
sw short wing 0.018
Klp61F Kinesin-like protein at 61F 0.018
sima similar 0.017
Caps Calcium activated protein for secretion 0.017
Cap-G CG34438 gene product from transcript CG34438-RF 0.017
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Homo sapiens
Name Description Probability Func Analog Organism
INCENP inner centromere protein antigens 135/155kDa 0.245
ITGB4 integrin, beta 4 0.084
PSEN2 presenilin 2 (Alzheimer disease 4) 0.064
CDCA8 cell division cycle associated 8 0.063
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.057
EXOC1 exocyst complex component 1 0.043
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.039
RACGAP1 Rac GTPase activating protein 1 0.035
CDK2 cyclin-dependent kinase 2 0.034
KIF1B kinesin family member 1B 0.032
GLIS2 GLIS family zinc finger 2 0.027
CENPJ centromere protein J 0.025
ANKRD28 ankyrin repeat domain 28 0.023
SASS6 spindle assembly 6 homolog (C. elegans) 0.020
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.020
KIF23 kinesin family member 23 0.019
ADRBK1 adrenergic, beta, receptor kinase 1 0.018
AKAP9 A kinase (PRKA) anchor protein (yotiao) 9 0.018
CDK1 cyclin-dependent kinase 1 0.016
DISC1 disrupted in schizophrenia 1 0.015
BIRC5 baculoviral IAP repeat containing 5 0.014
TEX11 testis expressed 11 0.013
LBR lamin B receptor 0.013
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.013
CCNA2 cyclin A2 0.012
EXOC2 exocyst complex component 2 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CLB3 Clb3p 0.010