Process View
The network for 'spinal cord association neuron differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
Shh | sonic hedgehog | 1.000 | |
Pax2 | paired box gene 2 | 1.000 | |
Pax3 | paired box gene 3 | 1.000 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 1.000 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.999 | |
Fgf8 | fibroblast growth factor 8 | 0.999 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.997 | |
Tbx1 | T-box 1 | 0.997 | |
Foxc2 | forkhead box C2 | 0.996 | |
Pax6 | paired box gene 6 | 0.995 | |
Lhx1 | LIM homeobox protein 1 | 0.995 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.987 | |
Msx1 | homeobox, msh-like 1 | 0.986 | |
Bmp4 | bone morphogenetic protein 4 | 0.985 | |
Foxc1 | forkhead box C1 | 0.983 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.979 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.963 | |
Rarg | retinoic acid receptor, gamma | 0.962 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.957 | |
Tcfap2a | transcription factor AP-2, alpha | 0.942 | |
En1 | engrailed 1 | 0.928 | |
Gbx2 | gastrulation brain homeobox 2 | 0.920 | |
Sox9 | SRY-box containing gene 9 | 0.918 | |
Smo | smoothened homolog (Drosophila) | 0.917 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.914 | |
Hoxa1 | homeobox A1 | 0.896 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.883 | |
Lhx3 | LIM homeobox protein 3 | 0.881 | |
Neurod1 | neurogenic differentiation 1 | 0.851 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.846 | |
Dlx5 | distal-less homeobox 5 | 0.840 | |
T | brachyury | 0.837 | |
Bmp7 | bone morphogenetic protein 7 | 0.828 | |
Rarb | retinoic acid receptor, beta | 0.827 | |
Gdnf | glial cell line derived neurotrophic factor | 0.792 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.773 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.767 | |
Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.767 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.759 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.754 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.749 | |
Hoxb3 | homeobox B3 | 0.737 | |
Nog | noggin | 0.736 | |
Hoxa2 | homeobox A2 | 0.724 | |
Tal1 | T-cell acute lymphocytic leukemia 1 | 0.702 | |
Hoxa11 | homeobox A11 | 0.694 | |
Phox2b | paired-like homeobox 2b | 0.689 | |
Hoxa10 | homeobox A10 | 0.686 | |
Hoxd3 | homeobox D3 | 0.666 | |
Hoxa3 | homeobox A3 | 0.661 | |
Hoxd13 | homeobox D13 | 0.641 | |
Gsc | goosecoid homeobox | 0.639 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.629 | |
Lmx1b | LIM homeobox transcription factor 1 beta | 0.623 | |
Gata4 | GATA binding protein 4 | 0.607 | |
Hoxb6 | homeobox B6 | 0.605 | |
Neurog2 | neurogenin 2 | 0.597 | |
Meox2 | mesenchyme homeobox 2 | 0.589 | |
Lhx5 | LIM homeobox protein 5 | 0.572 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.569 | |
Prrx2 | paired related homeobox 2 | 0.553 | |
Hoxa4 | homeobox A4 | 0.545 | |
Nodal | nodal | 0.542 | |
Sox11 | SRY-box containing gene 11 | 0.519 | |
Pou4f2 | POU domain, class 4, transcription factor 2 | 0.501 | |
Msx2 | homeobox, msh-like 2 | 0.492 | |
Pax7 | paired box gene 7 | 0.464 | |
Lhx9 | LIM homeobox protein 9 | 0.462 | |
Pax8 | paired box gene 8 | 0.428 | |
Chrd | chordin | 0.427 | |
Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.384 | |
Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.364 | |
Fgf15 | fibroblast growth factor 15 | 0.363 | |
Hoxd11 | homeobox D11 | 0.362 | |
Ptf1a | pancreas specific transcription factor, 1a | 0.361 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.359 | |
Prrx1 | paired related homeobox 1 | 0.357 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.352 | |
Fgf3 | fibroblast growth factor 3 | 0.346 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.337 | |
Barx1 | BarH-like homeobox 1 | 0.315 | |
Hoxd9 | homeobox D9 | 0.308 | |
Hoxd1 | homeobox D1 | 0.304 | |
Tgfb2 | transforming growth factor, beta 2 | 0.303 | |
Nhlh1 | nescient helix loop helix 1 | 0.298 | |
Hoxc8 | homeobox C8 | 0.295 | |
Gpr50 | G-protein-coupled receptor 50 | 0.292 | |
Wnt6 | wingless-related MMTV integration site 6 | 0.288 | |
Myf5 | myogenic factor 5 | 0.288 | |
Pax9 | paired box gene 9 | 0.284 | |
Onecut1 | one cut domain, family member 1 | 0.282 | |
Neurog1 | neurogenin 1 | 0.271 | |
Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.266 | |
Sox1 | SRY-box containing gene 1 | 0.263 | |
Foxb1 | forkhead box B1 | 0.263 | |
Myod1 | myogenic differentiation 1 | 0.262 | |
Sim1 | single-minded homolog 1 (Drosophila) | 0.262 | |
Bnc1 | basonuclin 1 | 0.261 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.257 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
gbx1 | gastrulation brain homeobox 1 | 0.635 | |
nkx2.2a | NK2 transcription factor related 2a | 0.528 | |
olig2 | oligodendrocyte lineage transcription factor 2 | 0.439 | |
gbx2 | gastrulation brain homeo box 2 | 0.405 | |
dbx1a | developing brain homeobox 1a | 0.398 | |
pax6a | paired box gene 6a | 0.256 | |
dld | deltaD | 0.192 | |
csf1ra | colony stimulating factor 1 receptor, a | 0.140 | |
mpped2 | metallophosphoesterase domain containing 2 | 0.133 | |
hoxb1a | homeo box B1a | 0.128 | |
eng2b | engrailed 2b | 0.108 | |
eng2a | engrailed 2a | 0.099 | |
otpb | orthopedia homolog b | 0.098 | |
osr2 | odd-skipped related 2 (Drosophila) | 0.091 | |
her8a | hairy-related 8a | 0.087 | |
lhx1a | LIM homeobox 1a | 0.087 | |
vsx2 | visual system homeobox 2 | 0.084 | |
pou3f3b | POU class 3 homeobox 3b | 0.084 | |
dlc | deltaC | 0.072 | |
pou3f1 | POU class 3 homeobox 1 | 0.065 | |
foxd3 | forkhead box D3 | 0.062 | |
gata1a | GATA binding protein 1a | 0.060 | |
notch1a | notch homolog 1a | 0.057 | |
aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.057 | |
flh | floating head | 0.056 | |
scube2 | signal peptide, CUB domain, EGF-like 2 | 0.048 | |
six3a | sine oculis homeobox homolog 3a | 0.047 | |
insm1b | insulinoma-associated 1b | 0.046 | |
foxb1.2 | forkhead box B1.2 | 0.044 | |
pax2a | paired box gene 2a | 0.044 | |
shha | sonic hedgehog a | 0.043 | |
dla | deltaA | 0.042 | |
id2a | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a | 0.041 | |
meis2.1 | myeloid ecotropic viral integration site 2.1 | 0.040 | |
isl1 | islet1 | 0.039 | |
gata2a | GATA-binding protein 2a | 0.039 | |
sox10 | SRY-box containing gene 10 | 0.038 | |
irx3a | iroquois homeobox protein 3a | 0.036 | |
nkx2.1b | NK2 homeobox 1b | 0.036 | |
nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.036 | |
vsx1 | visual system homeobox 1 homolog, chx10-like | 0.036 | |
meis3 | myeloid ecotropic viral integration site 3 | 0.036 | |
fgf8a | fibroblast growth factor 8 a | 0.035 | |
tfec | transcription factor EC | 0.035 | |
lef1 | lymphocyte enhancer binding factor 1 | 0.034 | |
nkx2.2b | NK2 transcription factor related 2b | 0.034 | |
neurog1 | neurogenin 1 | 0.034 | |
cdkn1c | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.034 | |
egr2b | early growth response 2b | 0.031 | |
hoxd11a | homeo box D11a | 0.030 | |
irx4a | iroquois homeobox protein 4a | 0.030 | |
ascl1b | achaete-scute complex-like 1b (Drosophila) | 0.029 | |
hnf1bb | HNF1 homeobox Bb | 0.029 | |
lhx5 | LIM homeobox 5 | 0.029 | |
hmx3 | homeo box (H6 family) 3 | 0.028 | |
eng1a | engrailed 1a | 0.027 | |
hoxb2a | homeo box B2a | 0.027 | |
zic2a | zic family member 2 (odd-paired homolog, Drosophila), a | 0.026 | |
dcc | deleted in colorectal carcinoma | 0.026 | |
phox2a | paired-like homeobox 2a | 0.025 | |
eng1b | engrailed 1b | 0.025 | |
gphn2 | gephyrin2 | 0.025 | |
zic4 | zic family member 4 | 0.025 | |
dab1a | disabled homolog 1a (Drosophila) | 0.024 | |
sox3 | SRY-box containing gene 3 | 0.024 | |
wnt11 | wingless-type MMTV integration site family, member 11 | 0.024 | |
otx1b | orthodenticle homolog 1b | 0.023 | |
nkx6.1 | NK6 transcription factor related, locus 1 (Drosophila) | 0.023 | |
fezf2 | FEZ family zinc finger 2 | 0.023 | |
oprd1b | opioid receptor, delta 1b | 0.023 | |
tal1 | T-cell acute lymphocytic leukemia 1 | 0.023 | |
fzd5 | frizzled homolog 5 | 0.022 | |
fgf8b | fibroblast growth factor 8 b | 0.022 | |
hgfa | hepatocyte growth factor a | 0.022 | |
atoh7 | atonal homolog 7 | 0.022 | |
hnf1ba | HNF1 homeobox Ba | 0.021 | |
mapk14a | mitogen-activated protein kinase 14a | 0.021 | |
barhl2 | BarH-like 2 | 0.021 | |
olig3 | oligodendrocyte transcription factor 3 | 0.020 | |
etv2 | ets variant gene 2 | 0.020 | |
otx2 | orthodenticle homolog 2 | 0.020 | |
wnt3a | wingless-type MMTV integration site family, member 3A | 0.019 | |
rasl11b | RAS-like, family 11, member B | 0.018 | |
neurod | neurogenic differentiation | 0.018 | |
crestin | crestin | 0.018 | |
apc | adenomatosis polyposis coli | 0.018 | |
prl | prolactin | 0.018 | |
irx5a | iroquois homeobox protein 5a | 0.018 | |
ccbe1 | collagen and calcium binding EGF domains 1 | 0.016 | |
irx5b | iroquois homeobox protein 5b | 0.016 | |
sim1a | single-minded homolog 1a (Drosophila) | 0.016 | |
lfng | lunatic fringe homolog | 0.016 | |
rx3 | retinal homeobox gene 3 | 0.015 | |
ek1 | eph-like kinase 1 | 0.015 | |
vldlr | very low density lipoprotein receptor | 0.015 | |
ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.015 | |
med12 | mediator of RNA polymerase II transcription, subunit 12 homolog | 0.015 | |
her3 | hairy-related 3 | 0.015 | |
otpa | orthopedia homolog a | 0.015 | |
nog2 | noggin 2 | 0.014 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Rps27a | ribosomal protein S27a | 0.017 | |
Rpl35 | ribosomal protein L35 | 0.014 | |
Rpl23 | ribosomal protein L23 | 0.014 | |
Rps10 | ribosomal protein S10 | 0.013 | |
Rpl19 | ribosomal protein L19 | 0.013 | |
Rpl23a | ribosomal protein L23a | 0.012 | |
Rpl9 | ribosomal protein L9 | 0.011 | |
Uba52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.011 |