The network for 'spinal cord association neuron differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spinal cord association neuron differentiation

The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.

Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Shh sonic hedgehog 1.000
Pax2 paired box gene 2 1.000
Pax3 paired box gene 3 1.000
Isl1 ISL1 transcription factor, LIM/homeodomain 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Fgf8 fibroblast growth factor 8 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.997
Tbx1 T-box 1 0.997
Foxc2 forkhead box C2 0.996
Pax6 paired box gene 6 0.995
Lhx1 LIM homeobox protein 1 0.995
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.987
Msx1 homeobox, msh-like 1 0.986
Bmp4 bone morphogenetic protein 4 0.985
Foxc1 forkhead box C1 0.983
Hand2 heart and neural crest derivatives expressed transcript 2 0.979
Lmx1a LIM homeobox transcription factor 1 alpha 0.963
Rarg retinoic acid receptor, gamma 0.962
Emx2 empty spiracles homolog 2 (Drosophila) 0.957
Tcfap2a transcription factor AP-2, alpha 0.942
En1 engrailed 1 0.928
Gbx2 gastrulation brain homeobox 2 0.920
Sox9 SRY-box containing gene 9 0.918
Smo smoothened homolog (Drosophila) 0.917
Gli2 GLI-Kruppel family member GLI2 0.914
Hoxa1 homeobox A1 0.896
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.883
Lhx3 LIM homeobox protein 3 0.881
Neurod1 neurogenic differentiation 1 0.851
Emx1 empty spiracles homolog 1 (Drosophila) 0.846
Dlx5 distal-less homeobox 5 0.840
T brachyury 0.837
Bmp7 bone morphogenetic protein 7 0.828
Rarb retinoic acid receptor, beta 0.827
Gdnf glial cell line derived neurotrophic factor 0.792
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.773
Eya1 eyes absent 1 homolog (Drosophila) 0.767
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.767
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.759
Wnt3a wingless-related MMTV integration site 3A 0.754
Otx1 orthodenticle homolog 1 (Drosophila) 0.749
Hoxb3 homeobox B3 0.737
Nog noggin 0.736
Hoxa2 homeobox A2 0.724
Tal1 T-cell acute lymphocytic leukemia 1 0.702
Hoxa11 homeobox A11 0.694
Phox2b paired-like homeobox 2b 0.689
Hoxa10 homeobox A10 0.686
Hoxd3 homeobox D3 0.666
Hoxa3 homeobox A3 0.661
Hoxd13 homeobox D13 0.641
Gsc goosecoid homeobox 0.639
Fgfr2 fibroblast growth factor receptor 2 0.629
Lmx1b LIM homeobox transcription factor 1 beta 0.623
Gata4 GATA binding protein 4 0.607
Hoxb6 homeobox B6 0.605
Neurog2 neurogenin 2 0.597
Meox2 mesenchyme homeobox 2 0.589
Lhx5 LIM homeobox protein 5 0.572
Hand1 heart and neural crest derivatives expressed transcript 1 0.569
Prrx2 paired related homeobox 2 0.553
Hoxa4 homeobox A4 0.545
Nodal nodal 0.542
Sox11 SRY-box containing gene 11 0.519
Pou4f2 POU domain, class 4, transcription factor 2 0.501
Msx2 homeobox, msh-like 2 0.492
Pax7 paired box gene 7 0.464
Lhx9 LIM homeobox protein 9 0.462
Pax8 paired box gene 8 0.428
Chrd chordin 0.427
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.384
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.364
Fgf15 fibroblast growth factor 15 0.363
Hoxd11 homeobox D11 0.362
Ptf1a pancreas specific transcription factor, 1a 0.361
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.359
Prrx1 paired related homeobox 1 0.357
Zic3 zinc finger protein of the cerebellum 3 0.352
Fgf3 fibroblast growth factor 3 0.346
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.337
Barx1 BarH-like homeobox 1 0.315
Hoxd9 homeobox D9 0.308
Hoxd1 homeobox D1 0.304
Tgfb2 transforming growth factor, beta 2 0.303
Nhlh1 nescient helix loop helix 1 0.298
Hoxc8 homeobox C8 0.295
Gpr50 G-protein-coupled receptor 50 0.292
Wnt6 wingless-related MMTV integration site 6 0.288
Myf5 myogenic factor 5 0.288
Pax9 paired box gene 9 0.284
Onecut1 one cut domain, family member 1 0.282
Neurog1 neurogenin 1 0.271
Hes5 hairy and enhancer of split 5 (Drosophila) 0.266
Sox1 SRY-box containing gene 1 0.263
Foxb1 forkhead box B1 0.263
Myod1 myogenic differentiation 1 0.262
Sim1 single-minded homolog 1 (Drosophila) 0.262
Bnc1 basonuclin 1 0.261
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.257
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
gbx1 gastrulation brain homeobox 1 0.635
nkx2.2a NK2 transcription factor related 2a 0.528
olig2 oligodendrocyte lineage transcription factor 2 0.439
gbx2 gastrulation brain homeo box 2 0.405
dbx1a developing brain homeobox 1a 0.398
pax6a paired box gene 6a 0.256
dld deltaD 0.192
csf1ra colony stimulating factor 1 receptor, a 0.140
mpped2 metallophosphoesterase domain containing 2 0.133
hoxb1a homeo box B1a 0.128
eng2b engrailed 2b 0.108
eng2a engrailed 2a 0.099
otpb orthopedia homolog b 0.098
osr2 odd-skipped related 2 (Drosophila) 0.091
her8a hairy-related 8a 0.087
lhx1a LIM homeobox 1a 0.087
vsx2 visual system homeobox 2 0.084
pou3f3b POU class 3 homeobox 3b 0.084
dlc deltaC 0.072
pou3f1 POU class 3 homeobox 1 0.065
foxd3 forkhead box D3 0.062
gata1a GATA binding protein 1a 0.060
notch1a notch homolog 1a 0.057
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.057
flh floating head 0.056
scube2 signal peptide, CUB domain, EGF-like 2 0.048
six3a sine oculis homeobox homolog 3a 0.047
insm1b insulinoma-associated 1b 0.046
foxb1.2 forkhead box B1.2 0.044
pax2a paired box gene 2a 0.044
shha sonic hedgehog a 0.043
dla deltaA 0.042
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.041
meis2.1 myeloid ecotropic viral integration site 2.1 0.040
isl1 islet1 0.039
gata2a GATA-binding protein 2a 0.039
sox10 SRY-box containing gene 10 0.038
irx3a iroquois homeobox protein 3a 0.036
nkx2.1b NK2 homeobox 1b 0.036
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.036
vsx1 visual system homeobox 1 homolog, chx10-like 0.036
meis3 myeloid ecotropic viral integration site 3 0.036
fgf8a fibroblast growth factor 8 a 0.035
tfec transcription factor EC 0.035
lef1 lymphocyte enhancer binding factor 1 0.034
nkx2.2b NK2 transcription factor related 2b 0.034
neurog1 neurogenin 1 0.034
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.034
egr2b early growth response 2b 0.031
hoxd11a homeo box D11a 0.030
irx4a iroquois homeobox protein 4a 0.030
ascl1b achaete-scute complex-like 1b (Drosophila) 0.029
hnf1bb HNF1 homeobox Bb 0.029
lhx5 LIM homeobox 5 0.029
hmx3 homeo box (H6 family) 3 0.028
eng1a engrailed 1a 0.027
hoxb2a homeo box B2a 0.027
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.026
dcc deleted in colorectal carcinoma 0.026
phox2a paired-like homeobox 2a 0.025
eng1b engrailed 1b 0.025
gphn2 gephyrin2 0.025
zic4 zic family member 4 0.025
dab1a disabled homolog 1a (Drosophila) 0.024
sox3 SRY-box containing gene 3 0.024
wnt11 wingless-type MMTV integration site family, member 11 0.024
otx1b orthodenticle homolog 1b 0.023
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.023
fezf2 FEZ family zinc finger 2 0.023
oprd1b opioid receptor, delta 1b 0.023
tal1 T-cell acute lymphocytic leukemia 1 0.023
fzd5 frizzled homolog 5 0.022
fgf8b fibroblast growth factor 8 b 0.022
hgfa hepatocyte growth factor a 0.022
atoh7 atonal homolog 7 0.022
hnf1ba HNF1 homeobox Ba 0.021
mapk14a mitogen-activated protein kinase 14a 0.021
barhl2 BarH-like 2 0.021
olig3 oligodendrocyte transcription factor 3 0.020
etv2 ets variant gene 2 0.020
otx2 orthodenticle homolog 2 0.020
wnt3a wingless-type MMTV integration site family, member 3A 0.019
rasl11b RAS-like, family 11, member B 0.018
neurod neurogenic differentiation 0.018
crestin crestin 0.018
apc adenomatosis polyposis coli 0.018
prl prolactin 0.018
irx5a iroquois homeobox protein 5a 0.018
ccbe1 collagen and calcium binding EGF domains 1 0.016
irx5b iroquois homeobox protein 5b 0.016
sim1a single-minded homolog 1a (Drosophila) 0.016
lfng lunatic fringe homolog 0.016
rx3 retinal homeobox gene 3 0.015
ek1 eph-like kinase 1 0.015
vldlr very low density lipoprotein receptor 0.015
ascl1a achaete-scute complex-like 1a (Drosophila) 0.015
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.015
her3 hairy-related 3 0.015
otpa orthopedia homolog a 0.015
nog2 noggin 2 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rps27a ribosomal protein S27a 0.017
Rpl35 ribosomal protein L35 0.014
Rpl23 ribosomal protein L23 0.014
Rps10 ribosomal protein S10 0.013
Rpl19 ribosomal protein L19 0.013
Rpl23a ribosomal protein L23a 0.012
Rpl9 ribosomal protein L9 0.011
Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism