The network for 'neutrophil mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neutrophil mediated immunity

Any process involved in the carrying out of an immune response by a neutrophil.

Mus musculus
Name Description Probability Func Analog Organism
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.669
Il1rn interleukin 1 receptor antagonist 0.502
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.480
Hcst hematopoietic cell signal transducer 0.440
Mefv Mediterranean fever 0.428
Rab27a RAB27A, member RAS oncogene family 0.402
C5ar1 complement component 5a receptor 1 0.390
Vav2 vav 2 oncogene 0.387
Mmp8 matrix metallopeptidase 8 0.383
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.311
Cma1 chymase 1, mast cell 0.281
Cd247 CD247 antigen 0.253
Mpo myeloperoxidase 0.225
Il18rap interleukin 18 receptor accessory protein 0.207
Nfam1 Nfat activating molecule with ITAM motif 1 0.204
Slfn4 schlafen 4 0.196
Ngp neutrophilic granule protein 0.196
Ctsg cathepsin G 0.195
Camp cathelicidin antimicrobial peptide 0.193
Clec4e C-type lectin domain family 4, member e 0.172
Prf1 perforin 1 (pore forming protein) 0.166
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.162
Mlph melanophilin 0.149
Mb myoglobin 0.135
Gzmb granzyme B 0.132
Fpr1 formyl peptide receptor 1 0.130
Cxcr2 chemokine (C-X-C motif) receptor 2 0.124
F10 coagulation factor X 0.120
Rag2 recombination activating gene 2 0.112
Elane elastase, neutrophil expressed 0.112
Ifitm6 interferon induced transmembrane protein 6 0.111
Batf basic leucine zipper transcription factor, ATF-like 0.111
Ren1 renin 1 structural 0.107
Irg1 immunoresponsive gene 1 0.107
Hps1 Hermansky-Pudlak syndrome 1 homolog (human) 0.106
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.106
Cd3e CD3 antigen, epsilon polypeptide 0.100
Plaur plasminogen activator, urokinase receptor 0.098
Trem3 triggering receptor expressed on myeloid cells 3 0.098
Mcpt4 mast cell protease 4 0.098
Tbxas1 thromboxane A synthase 1, platelet 0.097
Il2rb interleukin 2 receptor, beta chain 0.095
Adam8 a disintegrin and metallopeptidase domain 8 0.093
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.092
Pilra paired immunoglobin-like type 2 receptor alpha 0.090
Selp selectin, platelet 0.088
Prol1 proline rich, lacrimal 1 0.087
Cxcl2 chemokine (C-X-C motif) ligand 2 0.087
Tnfaip2 tumor necrosis factor, alpha-induced protein 2 0.086
Niacr1 niacin receptor 1 0.080
BC013712 cDNA sequence BC013712 0.076
Slpi secretory leukocyte peptidase inhibitor 0.074
Ltf lactotransferrin 0.074
Mitf microphthalmia-associated transcription factor 0.072
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.069
Sla src-like adaptor 0.069
Igk immunoglobulin kappa chain complex 0.066
Cst7 cystatin F (leukocystatin) 0.065
Ltc4s leukotriene C4 synthase 0.064
Lrrk2 leucine-rich repeat kinase 2 0.064
Mmp10 matrix metallopeptidase 10 0.063
Fasl Fas ligand (TNF superfamily, member 6) 0.061
Gp1ba glycoprotein 1b, alpha polypeptide 0.061
Clec4d C-type lectin domain family 4, member d 0.059
Ltb4r1 leukotriene B4 receptor 1 0.059
Ccl7 chemokine (C-C motif) ligand 7 0.059
Cxcr3 chemokine (C-X-C motif) receptor 3 0.059
Fes feline sarcoma oncogene 0.058
Col4a4 collagen, type IV, alpha 4 0.057
Clec7a C-type lectin domain family 7, member a 0.055
Hk3 hexokinase 3 0.054
Cpa3 carboxypeptidase A3, mast cell 0.053
Fpr2 formyl peptide receptor 2 0.053
Clec5a C-type lectin domain family 5, member a 0.053
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.053
Itgax integrin alpha X 0.053
Gpr35 G protein-coupled receptor 35 0.049
Fcna ficolin A 0.048
Il1f9 interleukin 1 family, member 9 0.048
Mcpt8 mast cell protease 8 0.048
Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide 0.046
Chi3l1 chitinase 3-like 1 0.046
Itgam integrin alpha M 0.046
Cd33 CD33 antigen 0.045
Gpr97 G protein-coupled receptor 97 0.045
Cidec cell death-inducing DFFA-like effector c 0.044
Glis2 GLIS family zinc finger 2 0.043
Ptgir prostaglandin I receptor (IP) 0.043
Mmp12 matrix metallopeptidase 12 0.043
Fcgr1 Fc receptor, IgG, high affinity I 0.043
Mcpt1 mast cell protease 1 0.043
Cd300lb CD300 antigen like family member B 0.042
Actn4 actinin alpha 4 0.041
Ncf4 neutrophil cytosolic factor 4 0.041
Clnk cytokine-dependent hematopoietic cell linker 0.041
Ubd ubiquitin D 0.041
Cd300ld CD300 molecule-like family member d 0.041
Spry4 sprouty homolog 4 (Drosophila) 0.040
Trem1 triggering receptor expressed on myeloid cells 1 0.040
F7 coagulation factor VII 0.039
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.661
rhogb ras homolog gene family, member Gb 0.429
ptprc protein tyrosine phosphatase, receptor type, C 0.237
coro1a coronin, actin binding protein, 1A 0.220
lrrc33 leucine rich repeat containing 33 0.152
ncf1 neutrophil cytosolic factor 1 0.151
im:7154036 im:7154036 0.120
iqgap1 IQ motif containing GTPase activating protein 1 0.076
lta4h leukotriene A4 hydrolase 0.072
mmp13a matrix metalloproteinase 13a 0.068
cxcr3.2 chemokine (C-X-C motif) receptor 3.2 0.064
zgc:110010 zgc:110010 0.064
clic1 chloride intracellular channel 1 0.062
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.061
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.061
ippk inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.057
gtf2a1 general transcription factor IIA, 1 0.057
zgc:63831 zgc:63831 0.055
sla1 Src-like-adaptor 1 0.055
mmp9 matrix metalloproteinase 9 0.054
itm2bb integral membrane protein 2Bb 0.051
lgals9l1 lectin, galactoside-binding, soluble, 9 (galectin 9)-like 1 0.050
grap2b GRB2-related adaptor protein 2b 0.048
yrk Yes-related kinase 0.041
mapk3 mitogen-activated protein kinase 3 0.037
b4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.034
ube2i2 ubiquitin-conjugating enzyme E2I2 0.034
gmfg glia maturation factor, gamma 0.033
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.032
si:dkey-12o15.1 si:dkey-12o15.1 0.029
arpc5b actin related protein 2/3 complex, subunit 5B 0.029
por P450 (cytochrome) oxidoreductase 0.029
ints6 integrator complex subunit 6 0.029
tnrc5 trinucleotide repeat containing 5 0.028
zgc:66242 zgc:66242 0.028
LOC553366 hypothetical protein LOC553366 0.027
zgc:153073 zgc:153073 0.027
atat1 alpha tubulin acetyltransferase 1 0.026
tnfaip8l2a tumor necrosis factor, alpha-induced protein 8, like 2a 0.026
snf8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.026
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.026
foxn1 forkhead box N1 0.025
zgc:63691 zgc:63691 0.024
ef1 ETS-related factor1 0.024
thsd7a thrombospondin, type I, domain containing 7A 0.024
pgam1b phosphoglycerate mutase 1b 0.024
zgc:113279 zgc:113279 0.024
appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.023
zgc:65811 zgc:65811 0.022
si:ch211-175f11.2 si:ch211-175f11.2 0.022
adam8a a disintegrin and metalloproteinase domain 8a 0.022
zgc:56706 zgc:56706 0.022
ptk6a PTK6 protein tyrosine kinase 6a 0.022
sdcbp syndecan binding protein (syntenin) 0.022
cyt1 type I cytokeratin, enveloping layer 0.022
smad5 MAD homolog 5 (Drosophila) 0.021
ctsc cathepsin C 0.021
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.021
hist1h4l histone 1, H4, like 0.021
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.020
LOC100359374 BCL-WAV 0.020
cab39l1 calcium binding protein 39, like 1 0.020
uevld UEV and lactate/malate dehyrogenase domains 0.020
thy1 Thy-1 cell surface antigen 0.020
arf6 ADP-ribosylation factor 6 0.019
h1m linker histone H1M 0.019
rhoab ras homolog gene family, member Ab 0.018
rbm4.1 RNA binding motif protein 4.1 0.018
poc1bl POC1 centriolar protein homolog B (Chlamydomonas), like 0.018
capzb capping protein (actin filament) muscle Z-line, beta 0.018
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.018
ppp4ca protein phosphatase 4 (formerly X), catalytic subunit a 0.017
zgc:114201 zgc:114201 0.017
clstn2 calsyntenin 2 0.017
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.016
styk1 serine/threonine/tyrosine kinase 1 0.016
cotl1 coactosin-like 1 (Dictyostelium) 0.016
phf23b PHD finger protein 23b 0.016
map2k7 mitogen-activated protein kinase kinase 7 0.016
zgc:92647 zgc:92647 0.016
pak2a p21 (CDKN1A)-activated kinase 2a 0.016
rap2c RAP2C, member of RAS oncogene family 0.016
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.016
zgc:85947 zgc:85947 0.015
hnrpkl heterogeneous nuclear ribonucleoprotein K, like 0.015
serinc2 serine incorporator 2 0.015
entpd4 ectonucleoside triphosphate diphosphohydrolase 4 0.015
samsn1a SAM domain, SH3 domain and nuclear localisation signals, 1a 0.015
npsn nephrosin 0.015
cdc34a cell division cycle 34 homolog (S. cerevisiae) a 0.014
sult1st6 sulfotransferase family 1, cytosolic sulfotransferase 6 0.014
stat5.2 signal transducer and activator of transcription 5.2 0.014
degs2 degenerative spermatocyte homolog 2, lipid desaturase (Drosophila) 0.014
si:dkey-180p18.9 si:dkey-180p18.9 0.014
ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.014
cbln1 cerebellin 1 precursor 0.014
bon bonnie and clyde 0.014
tmem184a transmembrane protein 184a 0.014
crfb8 cytokine receptor family member b8 0.014
zgc:56010 zgc:56010 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
IL8 interleukin 8 0.978
CXCL2 chemokine (C-X-C motif) ligand 2 0.921
CYBA cytochrome b-245, alpha polypeptide 0.919
NCF4 neutrophil cytosolic factor 4, 40kDa 0.878
NCF2 neutrophil cytosolic factor 2 0.857
CXCL3 chemokine (C-X-C motif) ligand 3 0.770
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.747
PPL periplakin 0.585
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.569
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.488
CCL20 chemokine (C-C motif) ligand 20 0.182
ANXA2 annexin A2 0.180
IL6 interleukin 6 (interferon, beta 2) 0.157
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.147
SNAP23 synaptosomal-associated protein, 23kDa 0.126
PRKCD protein kinase C, delta 0.107
VAV1 vav 1 guanine nucleotide exchange factor 0.101
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.093
CAV2 caveolin 2 0.091
KRT8 keratin 8 0.086
S100A11 S100 calcium binding protein A11 0.081
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.081
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.080
BTK Bruton agammaglobulinemia tyrosine kinase 0.076
SOD2 superoxide dismutase 2, mitochondrial 0.076
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.074
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.072
IL1B interleukin 1, beta 0.070
PRKCB protein kinase C, beta 0.065
IER3 immediate early response 3 0.060
S100A10 S100 calcium binding protein A10 0.058
UBASH3B ubiquitin associated and SH3 domain containing B 0.056
CXCL5 chemokine (C-X-C motif) ligand 5 0.054
PRKCA protein kinase C, alpha 0.052
ANXA5 annexin A5 0.050
PFN1 profilin 1 0.050
TRIM9 tripartite motif containing 9 0.049
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.048
PDZK1 PDZ domain containing 1 0.047
ANXA4 annexin A4 0.045
PDCD6 programmed cell death 6 0.044
LAT linker for activation of T cells 0.037
MSN moesin 0.037
ITGB5 integrin, beta 5 0.036
INADL InaD-like (Drosophila) 0.034
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.034
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.033
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.032
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.032
CHMP2B chromatin modifying protein 2B 0.029
PLAUR plasminogen activator, urokinase receptor 0.028
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.028
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.027
EMP1 epithelial membrane protein 1 0.027
LIF leukemia inhibitory factor (cholinergic differentiation factor) 0.027
STK10 serine/threonine kinase 10 0.026
PTX3 pentraxin 3, long 0.026
ZC3H12A zinc finger CCCH-type containing 12A 0.025
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.025
MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 0.025
RGS12 regulator of G-protein signaling 12 0.025
CAV1 caveolin 1, caveolae protein, 22kDa 0.025
BCL2L1 BCL2-like 1 0.024
C5orf41 chromosome 5 open reading frame 41 0.024
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.023
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.023
DSTN destrin (actin depolymerizing factor) 0.022
ANXA1 annexin A1 0.022
MMP1 matrix metallopeptidase 1 (interstitial collagenase) 0.021
CAPG capping protein (actin filament), gelsolin-like 0.021
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.021
KIAA0776 KIAA0776 0.020
CDCP1 CUB domain containing protein 1 0.020
MVP major vault protein 0.020
EMP3 epithelial membrane protein 3 0.019
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.019
DEF6 differentially expressed in FDCP 6 homolog (mouse) 0.019
SPRY4 sprouty homolog 4 (Drosophila) 0.019
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.019
AZU1 azurocidin 1 0.019
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.018
LAMC2 laminin, gamma 2 0.018
TNRC6B trinucleotide repeat containing 6B 0.018
EGR1 early growth response 1 0.018
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 0.018
ADAM9 ADAM metallopeptidase domain 9 0.018
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.018
PSD4 pleckstrin and Sec7 domain containing 4 0.018
RNASE3 ribonuclease, RNase A family, 3 0.017
LAMP2 lysosomal-associated membrane protein 2 0.017
CCNK cyclin K 0.017
CCL2 chemokine (C-C motif) ligand 2 0.017
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.017
MET met proto-oncogene (hepatocyte growth factor receptor) 0.017
PRTN3 proteinase 3 0.017
DPP4 dipeptidyl-peptidase 4 0.017
MYL12B myosin, light chain 12B, regulatory 0.016
ICAM1 intercellular adhesion molecule 1 0.016
VCAM1 vascular cell adhesion molecule 1 0.016
ANXA3 annexin A3 0.016
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism