The network for 'g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

Mus musculus
Name Description Probability Func Analog Organism
Drd2 dopamine receptor D2 1.000
Esr1 estrogen receptor 1 (alpha) 0.996
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.918
Kl klotho 0.917
Thrb thyroid hormone receptor beta 0.910
Kiss1r KISS1 receptor 0.895
Ren1 renin 1 structural 0.894
Pgr progesterone receptor 0.885
Cckbr cholecystokinin B receptor 0.838
Lep leptin 0.785
Tacr1 tachykinin receptor 1 0.742
Wnt2b wingless related MMTV integration site 2b 0.725
Nos1 nitric oxide synthase 1, neuronal 0.722
Npy1r neuropeptide Y receptor Y1 0.706
Adrb1 adrenergic receptor, beta 1 0.692
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.688
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.685
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.681
Sstr4 somatostatin receptor 4 0.669
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.668
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.665
Ar androgen receptor 0.632
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.615
Npy2r neuropeptide Y receptor Y2 0.600
Cga glycoprotein hormones, alpha subunit 0.564
Lepr leptin receptor 0.562
Kcns2 K+ voltage-gated channel, subfamily S, 2 0.546
Oprm1 opioid receptor, mu 1 0.541
Cx3cr1 chemokine (C-X3-C) receptor 1 0.536
Adora2a adenosine A2a receptor 0.533
Has1 hyaluronan synthase1 0.526
Pax8 paired box gene 8 0.510
Crhr1 corticotropin releasing hormone receptor 1 0.504
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.492
Gnrh1 gonadotropin releasing hormone 1 0.485
Sstr1 somatostatin receptor 1 0.482
Pnpla2 patatin-like phospholipase domain containing 2 0.474
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.470
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.447
Tgfb1 transforming growth factor, beta 1 0.447
Tac2 tachykinin 2 0.435
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.428
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.414
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.413
Agrp agouti related protein 0.413
Prop1 paired like homeodomain factor 1 0.396
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.389
Fshr follicle stimulating hormone receptor 0.380
Gdnf glial cell line derived neurotrophic factor 0.371
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.370
Shc3 src homology 2 domain-containing transforming protein C3 0.370
Hcrt hypocretin 0.368
Lhx3 LIM homeobox protein 3 0.358
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.355
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.351
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.332
Hic1 hypermethylated in cancer 1 0.323
Mfap2 microfibrillar-associated protein 2 0.320
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.313
Trh thyrotropin releasing hormone 0.299
Npy5r neuropeptide Y receptor Y5 0.297
Sstr2 somatostatin receptor 2 0.289
Krt86 keratin 86 0.288
Gast gastrin 0.285
Gpr12 G-protein coupled receptor 12 0.284
Fgf5 fibroblast growth factor 5 0.283
Vdr vitamin D receptor 0.280
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.280
Adra2b adrenergic receptor, alpha 2b 0.274
Esr2 estrogen receptor 2 (beta) 0.269
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 0.266
Oprd1 opioid receptor, delta 1 0.265
Fgf10 fibroblast growth factor 10 0.260
Dlx4 distal-less homeobox 4 0.252
Adra1a adrenergic receptor, alpha 1a 0.252
Pspn persephin 0.249
Gsx1 GS homeobox 1 0.248
Syn2 synapsin II 0.244
Gli2 GLI-Kruppel family member GLI2 0.244
Pramel7 preferentially expressed antigen in melanoma like 7 0.242
Ptprn2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.241
Tll1 tolloid-like 0.238
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.236
Pthlh parathyroid hormone-like peptide 0.234
Kiss1 KiSS-1 metastasis-suppressor 0.229
Gpr132 G protein-coupled receptor 132 0.229
Slc12a5 solute carrier family 12, member 5 0.227
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.225
Mc5r melanocortin 5 receptor 0.223
Krt77 keratin 77 0.220
S1pr2 sphingosine-1-phosphate receptor 2 0.209
Oprk1 opioid receptor, kappa 1 0.209
Myh11 myosin, heavy polypeptide 11, smooth muscle 0.208
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.205
Musk muscle, skeletal, receptor tyrosine kinase 0.204
Ptgs2 prostaglandin-endoperoxide synthase 2 0.200
Tpo thyroid peroxidase 0.199
Dio2 deiodinase, iodothyronine, type II 0.197
Thra thyroid hormone receptor alpha 0.195
Cntn3 contactin 3 0.195
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
drd2b dopamine receptor D2b 0.990
oprk1 opioid receptor, kappa 1 0.873
drd2a dopamine receptor D2a 0.477
oprd1a opioid receptor, delta 1a 0.444
drd2l dopamine receptor D2 like 0.444
vipr2 vasoactive intestinal peptide receptor 2 0.430
adcyap1r1a adenylate cyclase activating polypeptide 1 receptor 1a 0.371
mc4r melanocortin 4 receptor 0.344
calcrla calcitonin receptor-like a 0.283
adra2b adrenergic, alpha-2B-, receptor 0.265
igfbp6a insulin-like growth factor binding protein 6a 0.259
pcsk1nl proprotein convertase subtilisin/kexin type 1 inhibitor, like 0.212
adrb2a adrenergic receptor, beta 2a 0.167
lifrb leukemia inhibitory factor receptor alpha b 0.162
penka proenkephalin a 0.151
si:ch211-124k10.1 si:ch211-124k10.1 0.142
npy8br neuropeptide Y receptor Y8b 0.141
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.135
uts1 urotensin 1 0.132
pcp4a Purkinje cell protein 4a 0.123
nlgn1 neuroligin 1 0.118
avpl arginine vasopressin-like 0.112
oprd1b opioid receptor, delta 1b 0.110
mao monoamine oxidase 0.108
gria2b glutamate receptor, ionotropic, AMPA 2b 0.104
gli2a GLI-Kruppel family member GLI2a 0.098
nlgn2a neuroligin 2a 0.095
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.090
alk anaplastic lymphoma kinase (Ki-1) 0.084
nlgn2b neuroligin 2b 0.079
otpa orthopedia homolog a 0.077
adra2db adrenergic, alpha-2D-, receptor b 0.074
kif5c kinesin family member 5C 0.072
si:ch211-14k19.8 si:ch211-14k19.8 0.068
kiss2 kisspeptin 2 0.067
insl5b insulin-like 5b 0.058
ahr1a aryl hydrocarbon receptor 1a 0.057
nlgn3b neuroligin 3b 0.057
hcrtr2 hypocretin (orexin) receptor 2 0.055
crabp1a cellular retinoic acid binding protein 1a 0.053
mc2r melanocortin 2 receptor 0.047
LOC569642 hypothetical protein LOC569642 0.045
fgfrl1b fibroblast growth factor receptor-like 1b 0.043
drd3 dopamine receptor D3 0.042
rln3a relaxin 3a 0.041
nrg2a neuregulin 2a 0.039
nlgn4a neuroligin 4a 0.038
ptgs1 prostaglandin-endoperoxide synthase 1 0.037
crabp1b cellular retinoic acid binding protein 1b 0.034
ctsba cathepsin B, a 0.032
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.032
m17 IL-6 subfamily cytokine M17 0.031
ca8 carbonic anhydrase VIII 0.031
inha inhibin, alpha 0.030
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.030
slc5a8l solute carrier family 5 (iodide transporter), member 8-like 0.027
oprm1 opioid receptor, mu 1 0.027
cx52.6 connexin 52.6 0.027
cadm2b cell adhesion molecule 2b 0.027
camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.027
si:dkey-110c1.1 si:dkey-110c1.1 0.026
ctsl1a cathepsin L, 1 a 0.026
grm1a glutamate receptor, metabotropic 1a 0.025
lhb luteinizing hormone, beta polypeptide 0.025
oxtl oxytocin-like 0.025
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.024
calcr calcitonin receptor 0.024
fes feline sarcoma oncogene 0.023
agrp agouti related protein homolog 0.023
nlgn4b neuroligin 4b 0.022
nes nestin 0.022
gnrh2 gonadotropin-releasing hormone 2 0.021
csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.021
LOC100332193 growth hormone secretagogue receptor type 1-like 0.021
si:ch211-212m21.5 si:ch211-212m21.5 0.021
si:dkey-228g21.4 si:dkey-228g21.4 0.021
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.021
nf1b neurofibromin 1b 0.020
paqr7b progestin and adipoQ receptor family member VII, b 0.020
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.020
vip vasoactive intestinal peptide 0.020
fshb follicle stimulating hormone, beta polypeptide 0.020
pdlim1 PDZ and LIM domain 1 (elfin) 0.019
fshr follicle stimulating hormone receptor 0.019
cnga5 cyclic nucleotide gated channel alpha 5 0.019
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.019
LOC799274 kinesin heavy chain isoform 5A-like 0.018
mc1r melanocortin 1 receptor 0.017
mfn2 mitofusin 2 0.017
cyp1d1 cytochrome P450, family 1, subfamily D, polypeptide 1 0.017
rap1b RAS related protein 1b 0.017
LOC555504 novel protocadherin protein 0.017
paqr8 progestin and adipoQ receptor family member VIII 0.016
slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.016
igfbp6b insulin-like growth factor binding protein 6b 0.016
crh corticotropin releasing hormone 0.015
inhbaa inhibin, beta Aa 0.015
pmch pro-melanin concentrating hormone 0.015
adora2b adenosine A2b receptor 0.014
tlr21 toll-like receptor 21 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
CG42629 CG42629 gene product from transcript CG42629-RB 0.625
mtt mangetout 0.307
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.288
TyrR Tyramine receptor 0.287
5-HT1A Serotonin receptor 1A 0.260
Nmdar1 NMDA receptor 1 0.234
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.222
dnc dunce 0.220
CG13253 CG13253 gene product from transcript CG13253-RB 0.183
Ank2 Ankyrin 2 0.166
Mad Mothers against dpp 0.141
Clk Clock 0.140
Ac3 CG1506 gene product from transcript CG1506-RA 0.134
NPFR1 neuropeptide F receptor 0.127
dnr1 defense repressor 1 0.127
Tbh Tyramine beta hydroxylase 0.120
tim timeless 0.119
Atf-2 Activating transcription factor-2 0.113
Pde8 Phosphodiesterase 8 0.107
Dat Dopamine N acetyltransferase 0.106
RanBPM Ran-binding protein M 0.105
per period 0.096
CG18437 CG18437 gene product from transcript CG18437-RB 0.095
CG32813 CG32813 gene product from transcript CG32813-RE 0.092
Glut1 Glucose transporter 1 0.088
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.083
unc79 CG5237 gene product from transcript CG5237-RB 0.079
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.078
Eip63F-1 Ecdysone-induced protein 63F 1 0.072
CRMP Collapsin Response Mediator Protein 0.072
dhd deadhead 0.072
Gr28b Gustatory receptor 28b 0.065
cngl CNG channel-like 0.065
Dsk Drosulfakinin 0.062
5-HT1B Serotonin receptor 1B 0.058
Corin CG2105 gene product from transcript CG2105-RB 0.057
dpr20 CG12191 gene product from transcript CG12191-RA 0.054
Pdp1 PAR-domain protein 1 0.054
nord CG30418 gene product from transcript CG30418-RA 0.050
ppk pickpocket 0.048
ClC-a Chloride channel-a 0.045
CG34400 CG34400 gene product from transcript CG34400-RD 0.043
rho rhomboid 0.042
eys eyes shut 0.042
Hs3st-A Heparan sulfate 3-O sulfotransferase-A 0.040
sty sprouty 0.040
norpA no receptor potential A 0.038
Gr43a Gustatory receptor 43a 0.037
CG14274 CG14274 gene product from transcript CG14274-RA 0.037
mol moladietz 0.036
fd85E forkhead domain 85E 0.036
Ast-C Allatostatin C 0.036
GluRIIA Glutamate receptor IIA 0.034
KCNQ KCNQ potassium channel 0.034
unc-13-4A CG32381 gene product from transcript CG32381-RB 0.033
Nha2 Na[+]/H[+] hydrogen antiporter 2 0.032
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.032
CG34393 CG34393 gene product from transcript CG34393-RA 0.032
CG34347 CG34347 gene product from transcript CG34347-RB 0.032
foxo forkhead box, sub-group O 0.032
CG15479 CG15479 gene product from transcript CG15479-RA 0.031
oa2 octopamine receptor 2 0.030
Cpr92A Cuticular protein 92A 0.030
CG14459 CG14459 gene product from transcript CG14459-RB 0.029
CG14160 CG14160 gene product from transcript CG14160-RA 0.029
Ptp99A Protein tyrosine phosphatase 99A 0.028
CG14545 CG14545 gene product from transcript CG14545-RA 0.027
beat-Vb CG31298 gene product from transcript CG31298-RA 0.027
Vsx2 CG33980 gene product from transcript CG33980-RA 0.027
Ilp3 Insulin-like peptide 3 0.027
Gyc76C Guanylyl cyclase at 76C 0.026
Dh44-R1 Diuretic hormone 44 receptor 1 0.026
CG31999 CG31999 gene product from transcript CG31999-RA 0.026
CG33696 CG33696 gene product from transcript CG33696-RA 0.026
Socs36E Suppressor of cytokine signaling at 36E 0.026
Nmdar2 NMDA receptor 2 0.026
E(Pc) Enhancer of Polycomb 0.025
Spf45 CG17540 gene product from transcript CG17540-RB 0.025
mAcR-60C muscarinic Acetylcholine Receptor 60C 0.025
AR-2 Allatostatin Receptor 2 0.024
Pde6 Phosphodiesterase 6 0.024
Sox100B CG15552 gene product from transcript CG15552-RA 0.024
SIFR SIFamide receptor 0.024
CG15088 CG15088 gene product from transcript CG15088-RC 0.023
bin biniou 0.023
CG14570 CG14570 gene product from transcript CG14570-RA 0.023
Lcp65Ag1 CG10530 gene product from transcript CG10530-RA 0.022
CG9447 CG9447 gene product from transcript CG9447-RB 0.022
stet stem cell tumor 0.022
CG12851 CG12851 gene product from transcript CG12851-RB 0.022
D2R Dopamine 2-like receptor 0.021
Ric Ras which interacts with Calmodulin 0.021
CG10858 CG10858 gene product from transcript CG10858-RB 0.021
GABA-B-R3 metabotropic GABA-B receptor subtype 3 0.021
Cpr72Eb Cuticular protein 72Eb 0.021
CG1909 CG1909 gene product from transcript CG1909-RA 0.021
CG16778 CG16778 gene product from transcript CG16778-RA 0.021
Tre1 trapped in endoderm-1 0.021
CG5386 CG5386 gene product from transcript CG5386-RA 0.021
beat-Ic beaten path Ic 0.021
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Homo sapiens
Name Description Probability Func Analog Organism
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.999
DRD2 dopamine receptor D2 0.999
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.993
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.986
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.986
ARRB1 arrestin, beta 1 0.983
MPDZ multiple PDZ domain protein 0.966
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.936
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.925
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.902
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.802
ADORA2A adenosine A2a receptor 0.801
CRH corticotropin releasing hormone 0.755
PSEN1 presenilin 1 0.751
PTEN phosphatase and tensin homolog 0.722
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.675
TBC1D10A TBC1 domain family, member 10A 0.634
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.630
GPR6 G protein-coupled receptor 6 0.629
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.620
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.616
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.600
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.589
ADRB2 adrenergic, beta-2-, receptor, surface 0.575
NSF N-ethylmaleimide-sensitive factor 0.565
GHRHR growth hormone releasing hormone receptor 0.559
OPCML opioid binding protein/cell adhesion molecule-like 0.550
CHRNA4 cholinergic receptor, nicotinic, alpha 4 0.515
SSTR3 somatostatin receptor 3 0.514
RAP1A RAP1A, member of RAS oncogene family 0.491
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.440
CAV1 caveolin 1, caveolae protein, 22kDa 0.434
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.415
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.396
KCNJ5 potassium inwardly-rectifying channel, subfamily J, member 5 0.384
UBQLN1 ubiquilin 1 0.382
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A 0.382
NAMPT nicotinamide phosphoribosyltransferase 0.374
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.370
HTR4 5-hydroxytryptamine (serotonin) receptor 4 0.362
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.356
KCNH1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.338
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.329
PSEN2 presenilin 2 (Alzheimer disease 4) 0.313
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A 0.311
EZR ezrin 0.296
RALBP1 ralA binding protein 1 0.261
NUCB1 nucleobindin 1 0.259
SSTR2 somatostatin receptor 2 0.258
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B 0.257
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.256
FLNB filamin B, beta 0.255
CALCR calcitonin receptor 0.254
CRHR2 corticotropin releasing hormone receptor 2 0.253
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.251
PRKCG protein kinase C, gamma 0.246
PLD3 phospholipase D family, member 3 0.245
DRD1 dopamine receptor D1 0.238
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.227
CCKBR cholecystokinin B receptor 0.225
GRIP1 glutamate receptor interacting protein 1 0.221
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.215
HRH3 histamine receptor H3 0.213
FLNA filamin A, alpha 0.213
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C 0.213
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.210
OPRM1 opioid receptor, mu 1 0.209
NECAB2 N-terminal EF-hand calcium binding protein 2 0.207
BMP8A bone morphogenetic protein 8a 0.197
GFRA4 GDNF family receptor alpha 4 0.191
SSTR4 somatostatin receptor 4 0.187
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.186
ADRA1D adrenergic, alpha-1D-, receptor 0.185
OPRD1 opioid receptor, delta 1 0.184
GLP1R glucagon-like peptide 1 receptor 0.181
PTCH1 patched 1 0.177
GRIK3 glutamate receptor, ionotropic, kainate 3 0.176
CTSA cathepsin A 0.171
NEUROD2 neurogenic differentiation 2 0.171
FGF4 fibroblast growth factor 4 0.170
APLP2 amyloid beta (A4) precursor-like protein 2 0.166
GRN granulin 0.162
SLC6A7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.159
KCNJ3 potassium inwardly-rectifying channel, subfamily J, member 3 0.157
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.156
NPY2R neuropeptide Y receptor Y2 0.156
SCNN1G sodium channel, nonvoltage-gated 1, gamma 0.156
FTH1 ferritin, heavy polypeptide 1 0.155
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.155
CNGB1 cyclic nucleotide gated channel beta 1 0.153
GRM1 glutamate receptor, metabotropic 1 0.153
GFAP glial fibrillary acidic protein 0.151
EMX1 empty spiracles homeobox 1 0.151
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.150
FOXN1 forkhead box N1 0.148
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.143
CXCR5 chemokine (C-X-C motif) receptor 5 0.141
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.139
GRM6 glutamate receptor, metabotropic 6 0.136
KCNJ9 potassium inwardly-rectifying channel, subfamily J, member 9 0.135
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Rattus norvegicus
Name Description Probability Func Analog Organism
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.581
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.536
Folh1 folate hydrolase 1 0.515
Adora2a adenosine A2a receptor 0.426
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.423
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.421
Cmklr1 chemokine-like receptor 1 0.382
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.370
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.363
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.353
Ugt8 UDP glycosyltransferase 8 0.345
Olr416 olfactory receptor 416 0.314
Arhgap23 Rho GTPase activating protein 23 0.312
Fgf2 fibroblast growth factor 2 0.305
Cntn5 contactin 5 0.288
Smad3 SMAD family member 3 0.274
Syt8 synaptotagmin VIII 0.260
Drd1a dopamine receptor D1A 0.238
Adora1 adenosine A1 receptor 0.225
Smcp sperm mitochondria-associated cysteine-rich protein 0.218
Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.192
Oprk1 opioid receptor, kappa 1 0.183
Itgam integrin, alpha M 0.176
Epn2 epsin 2 0.171
Aqp2 aquaporin 2 (collecting duct) 0.171
Phkg1 phosphorylase kinase, gamma 1 0.167
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.164
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.152
Odf4 outer dense fiber of sperm tails 4 0.151
Adarb2 adenosine deaminase, RNA-specific, B2 0.148
Cntn1 contactin 1 0.146
LOC246267 resection-induced TPI (rs11) 0.143
Mchr1 melanin-concentrating hormone receptor 1 0.143
Gpr6 G protein-coupled receptor 6 0.142
Cntn3 contactin 3 (plasmacytoma associated) 0.140
Glra1 glycine receptor, alpha 1 0.133
Rgs9 regulator of G-protein signaling 9 0.132
Fgf14 fibroblast growth factor 14 0.131
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 0.130
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.129
Uhmk1 U2AF homology motif (UHM) kinase 1 0.129
Pnlip pancreatic lipase 0.127
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.125
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.124
Synpo synaptopodin 0.119
Acan aggrecan 0.116
Chrm4 cholinergic receptor, muscarinic 4 0.115
Nrp2 neuropilin 2 0.114
Grp gastrin releasing peptide 0.114
Vom2r53 vomeronasal 2 receptor, 53 0.113
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.113
Syt4 synaptotagmin IV 0.108
Hr hairless 0.106
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.103
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.103
Strn striatin, calmodulin binding protein 0.100
Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 0.099
Rftn2 raftlin family member 2 0.098
Sstr1 somatostatin receptor 1 0.098
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.098
Shox2 short stature homeobox 2 0.096
Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) 0.095
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.094
Drd2 dopamine receptor D2 0.094
Cga glycoprotein hormones, alpha polypeptide 0.092
Gpr61 G protein-coupled receptor 61 0.092
Chrnb3 cholinergic receptor, nicotinic, beta 3 0.090
Arpp21 cAMP-regulated phosphoprotein 21 0.089
Plcd4 phospholipase C, delta 4 0.087
Scn3a sodium channel, voltage-gated, type III, alpha 0.087
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.086
Mamdc4 MAM domain containing 4 0.086
Adam10 ADAM metallopeptidase domain 10 0.085
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.085
Map6 microtubule-associated protein 6 0.084
Nfasc neurofascin 0.084
Pth parathyroid hormone 0.083
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.082
Myo1d myosin ID 0.082
Pcdhb12 protocadherin beta 12 0.082
LOC100360919 Immunoglobulin lambda-like polypeptide 1-like 0.081
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.080
Syt7 synaptotagmin VII 0.079
Gfra2 GDNF family receptor alpha 2 0.075
Cd4 Cd4 molecule 0.075
Ncr1 natural cytotoxicity triggering receptor 1 0.070
Ptp4a2 protein tyrosine phosphatase 4a2 0.070
LOC100365195 rCG64293-like 0.070
Gad2 glutamate decarboxylase 2 0.070
Avp arginine vasopressin 0.070
Rxrg retinoid X receptor gamma 0.070
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.070
Neu2 sialidase 2 (cytosolic sialidase) 0.069
Ncan neurocan 0.068
Th tyrosine hydroxylase 0.068
Hoxa1 homeo box A1 0.067
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.067
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.067
Hrh3 histamine receptor H3 0.066
Oprd1 opioid receptor, delta 1 0.066
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GIS2 Gis2p 0.012
RPF2 Rpf2p 0.010