The network for 'osmosensory signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

osmosensory signaling pathway

The series of molecular signals initiated in response to osmotic change.

Mus musculus
Name Description Probability Func Analog Organism
Mapk14 mitogen-activated protein kinase 14 1.000
Mapk11 mitogen-activated protein kinase 11 0.983
Atf2 activating transcription factor 2 0.966
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.848
Mapkapk2 MAP kinase-activated protein kinase 2 0.843
Mapk9 mitogen-activated protein kinase 9 0.625
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.583
Rac1 RAS-related C3 botulinum substrate 1 0.561
Klc1 kinesin light chain 1 0.325
Mapk8 mitogen-activated protein kinase 8 0.273
Pten phosphatase and tensin homolog 0.193
Prkce protein kinase C, epsilon 0.188
Mapk1 mitogen-activated protein kinase 1 0.172
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.131
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.123
Cldn16 claudin 16 0.109
Adora3 adenosine A3 receptor 0.105
Mknk1 MAP kinase-interacting serine/threonine kinase 1 0.104
Mb myoglobin 0.100
Rtn2 reticulon 2 (Z-band associated protein) 0.085
Spag9 sperm associated antigen 9 0.075
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.068
Jun Jun oncogene 0.061
Map2k3 mitogen-activated protein kinase kinase 3 0.054
Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) 0.054
Gripap1 GRIP1 associated protein 1 0.052
Rgs12 regulator of G-protein signaling 12 0.051
Gng3 guanine nucleotide binding protein (G protein), gamma 3 0.044
Braf Braf transforming gene 0.043
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.039
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.039
Scg3 secretogranin III 0.039
Trp53 transformation related protein 53 0.038
Map2k4 mitogen-activated protein kinase kinase 4 0.034
Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 0.033
Raf1 v-raf-leukemia viral oncogene 1 0.033
Met met proto-oncogene 0.031
Mtmr1 myotubularin related protein 1 0.031
Thra thyroid hormone receptor alpha 0.031
Nos1 nitric oxide synthase 1, neuronal 0.031
Ly6h lymphocyte antigen 6 complex, locus H 0.031
Lcp1 lymphocyte cytosolic protein 1 0.030
Syt1 synaptotagmin I 0.030
Prkar1b protein kinase, cAMP dependent regulatory, type I beta 0.029
Kl klotho 0.028
Epn3 epsin 3 0.027
Fam48a family with sequence similarity 48, member A 0.025
Pea15a phosphoprotein enriched in astrocytes 15A 0.025
Celf4 CUGBP, Elav-like family member 4 0.024
Wnk4 WNK lysine deficient protein kinase 4 0.024
Mapk12 mitogen-activated protein kinase 12 0.023
Uchl1 ubiquitin carboxy-terminal hydrolase L1 0.023
Wwox WW domain-containing oxidoreductase 0.022
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.021
Homer1 homer homolog 1 (Drosophila) 0.021
Mib1 mindbomb homolog 1 (Drosophila) 0.021
Slc22a17 solute carrier family 22 (organic cation transporter), member 17 0.020
Csnk2b casein kinase 2, beta polypeptide 0.020
Nsf N-ethylmaleimide sensitive fusion protein 0.020
Nrsn1 neurensin 1 0.020
Aprt adenine phosphoribosyl transferase 0.020
Gsta4 glutathione S-transferase, alpha 4 0.019
Gap43 growth associated protein 43 0.019
Vcl vinculin 0.019
Pitpna phosphatidylinositol transfer protein, alpha 0.018
Mdm2 transformed mouse 3T3 cell double minute 2 0.018
Arhgap8 Rho GTPase activating protein 8 0.018
Grm1 glutamate receptor, metabotropic 1 0.017
Rnf111 ring finger 111 0.017
Npy neuropeptide Y 0.017
Syngr1 synaptogyrin 1 0.016
Dusp2 dual specificity phosphatase 2 0.016
Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 0.016
Ap1m2 adaptor protein complex AP-1, mu 2 subunit 0.016
Cldn3 claudin 3 0.016
Vill villin-like 0.015
Gnptab N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.015
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.014
Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.014
Clic3 chloride intracellular channel 3 0.014
Abr active BCR-related gene 0.014
Klc2 kinesin light chain 2 0.014
Glipr2 GLI pathogenesis-related 2 0.014
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.014
Tle1 transducin-like enhancer of split 1, homolog of Drosophila E(spl) 0.014
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.013
Ikbkg inhibitor of kappaB kinase gamma 0.013
Ncf1 neutrophil cytosolic factor 1 0.013
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.013
Uvrag UV radiation resistance associated gene 0.012
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.012
Selm selenoprotein M 0.012
Car11 carbonic anhydrase 11 0.012
Dlg1 discs, large homolog 1 (Drosophila) 0.012
Kbtbd2 kelch repeat and BTB (POZ) domain containing 2 0.012
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.012
Nenf neuron derived neurotrophic factor 0.012
Vdr vitamin D receptor 0.012
Fam131a family with sequence similarity 131, member A 0.012
Ncoa6 nuclear receptor coactivator 6 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PBS2 Pbs2p 0.984
SSK1 Ssk1p 0.952
SSK2 Ssk2p 0.785
STE11 Ste11p 0.681
CLA4 Cla4p 0.273
SSK22 Ssk22p 0.273
NBP2 Nbp2p 0.229
STE5 Ste5p 0.184
BEM3 Bem3p 0.171
PTP3 Ptp3p 0.125
PKC1 Pkc1p 0.107
MKK1 Mkk1p 0.105
ACK1 Ack1p 0.075
PTP2 Ptp2p 0.071
RGD1 Rgd1p 0.069
RHO1 Rho1p 0.067
HKR1 Hkr1p 0.066
CAK1 Cak1p 0.057
HAL5 Hal5p 0.045
KIC1 Kic1p 0.043
GIC2 Gic2p 0.039
MSG5 Msg5p 0.037
NUT2 Nut2p 0.036
OPY2 Opy2p 0.036
MSB2 Msb2p 0.031
MPS1 Mps1p 0.030
RAD9 Rad9p 0.030
MEC1 Mec1p 0.030
STE50 Ste50p 0.030
YDR348C hypothetical protein 0.030
YLR177W hypothetical protein 0.029
SMP1 Smp1p 0.026
ROD1 Rod1p 0.026
BST1 Bst1p 0.026
DIN7 Din7p 0.026
SUT1 Sut1p 0.026
CDC37 Cdc37p 0.026
RGD2 Rgd2p 0.026
MGS1 Mgs1p 0.024
CYK3 Cyk3p 0.023
TRS65 Trs65p 0.022
SRD1 Srd1p 0.021
FPS1 Fps1p 0.021
CBK1 Cbk1p 0.020
YNR014W hypothetical protein 0.019
HOT1 Hot1p 0.019
FPK1 Fpk1p 0.019
YLR264C-A hypothetical protein 0.019
LEU2 Leu2p 0.019
MER1 Mer1p 0.018
FYV8 Fyv8p 0.018
YSP2 Ysp2p 0.018
PTC5 Ptc5p 0.018
PCH2 Pch2p 0.018
HOP1 Hop1p 0.018
YOL038C-A hypothetical protein 0.017
YNL144C hypothetical protein 0.017
SWE1 Swe1p 0.017
YLR162W hypothetical protein 0.017
BCH2 Bch2p 0.017
PRS2 Prs2p 0.016
NUP42 Nup42p 0.016
MCM6 Mcm6p 0.016
SLT2 Slt2p 0.016
HSL1 Hsl1p 0.016
MSA1 Msa1p 0.015
CPD1 Cpd1p 0.015
FAR11 Far11p 0.015
HYM1 Hym1p 0.015
YLR042C hypothetical protein 0.015
YBR296C-A hypothetical protein 0.015
MYO5 Myo5p 0.015
RAD55 Rad55p 0.015
YIL151C hypothetical protein 0.015
BIT61 Bit61p 0.014
YAR068W hypothetical protein 0.014
PCL5 Pcl5p 0.014
CCH1 Cch1p 0.014
FIR1 Fir1p 0.014
ADH2 Adh2p 0.014
HXT4 Hxt4p 0.014
ATP6 Atp6p 0.014
BCK1 Bck1p 0.014
HXT3 Hxt3p 0.014
PTR2 Ptr2p 0.014
HLR1 Hlr1p 0.014
YJL107C hypothetical protein 0.014
CUP1-1 Cup1-1p 0.014
SSP1 Ssp1p 0.014
NDD1 Ndd1p 0.013
SRT1 Srt1p 0.013
RAD5 Rad5p 0.013
YPR157W hypothetical protein 0.013
YKR011C hypothetical protein 0.013
ZPS1 Zps1p 0.013
HPF1 Hpf1p 0.013
APA2 Apa2p 0.013
ARG8 Arg8p 0.013
YKR075C hypothetical protein 0.013
YMR102C hypothetical protein 0.013