The network for 'cardiac cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac cell development

The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.

Danio rerio
Name Description Probability Func Analog Organism
bmp4 bone morphogenetic protein 4 0.991
tnnc1b troponin C type 1b (slow) 0.964
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.917
myl7 myosin, light polypeptide 7, regulatory 0.859
nkx2.5 NK2 transcription factor related 5 0.849
mef2cb myocyte enhancer factor 2cb 0.718
ttna titin a 0.713
wnt11r wingless-type MMTV integration site family, member 11, related 0.683
bmp2b bone morphogenetic protein 2b 0.590
vmhc ventricular myosin heavy chain 0.583
tbx20 T-box 20 0.526
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.523
gja3 gap junction protein, alpha 3 0.523
pdlim7 PDZ and LIM domain 7 0.471
zgc:66286 zgc:66286 0.457
smyd1b SET and MYND domain containing 1b 0.440
tnni2a.4 troponin I, skeletal, fast 2a.4 0.380
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.377
scn12aa sodium channel, voltage gated, type XII, alpha a 0.331
tbx1 T-box 1 0.330
tnni1b troponin I, skeletal, slow b 0.325
desma desmin a 0.314
mef2ca myocyte enhancer factor 2ca 0.297
ttnb titin b 0.271
myl1 myosin, light chain 1, alkali; skeletal, fast 0.270
adrb2a adrenergic receptor, beta 2a 0.253
spaw southpaw 0.218
smyd1a SET and MYND domain containing 1a 0.217
kdrl kinase insert domain receptor like 0.210
notch1b notch homolog 1b 0.201
tnni1al troponin I, skeletal, slow like 0.195
lmna lamin A 0.187
cav3 caveolin 3 0.185
cx43 connexin 43 0.164
tbx18 T-box 18 0.159
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.158
wt1a wilms tumor 1a 0.152
neb nebulin 0.139
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.139
actn3b actinin alpha 3b 0.132
actc1b actin, alpha, cardiac muscle 1b 0.130
tnnt3b troponin T3b, skeletal, fast 0.128
wu:fb01h12 wu:fb01h12 0.123
tnnc2 troponin C type 2 (fast) 0.122
mylk3 myosin light chain kinase 3 0.119
lama4 laminin, alpha 4 0.119
smyhc2 slow myosin heavy chain 2 0.118
tbx5a T-box 5a 0.113
lrrc10 leucine rich repeat containing 10 0.103
spry4 sprouty (Drosophila) homolog 4 0.102
myf6 myogenic factor 6 0.101
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.099
casq2 calsequestrin 2 0.096
tnnc1a troponin C type 1a (slow) 0.096
actn2 actinin, alpha 2 0.095
txlnba taxilin beta a 0.095
myod1 myogenic differentiation 1 0.093
egr1 early growth response 1 0.089
actc1a actin, alpha, cardiac muscle 1a 0.087
vdra vitamin D receptor a 0.086
rnasel1 ribonuclease like 1 0.083
mylz2 myosin, light polypeptide 2, skeletal muscle 0.082
fabp11a fatty acid binding protein 11a 0.080
bmp10 bone morphogenetic protein 10 0.077
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.076
smyhc1 slow myosin heavy chain 1 0.073
xirp1 xin actin-binding repeat containing 1 0.072
duox dual oxidase 0.067
wu:fc31e07 wu:fc31e07 0.067
nppa natriuretic peptide precursor A 0.066
smyd2b SET and MYND domain containing 2b 0.065
aldoab aldolase a, fructose-bisphosphate, b 0.065
kbtbd10b kelch repeat and BTB (POZ) domain containing 10b 0.062
myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.061
hnf1ba HNF1 homeobox Ba 0.061
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.059
fxr1 fragile X mental retardation, autosomal homolog 1 0.058
fzd2 frizzled homolog 2 0.058
pax6b paired box gene 6b 0.058
gamt guanidinoacetate N-methyltransferase 0.056
sox9a SRY-box containing gene 9a 0.056
sox9b SRY-box containing gene 9b 0.056
tmem2 transmembrane protein 2 0.056
hspb8 heat shock protein, alpha-crystallin-related, b8 0.055
mybpc3 myosin binding protein C, cardiac 0.054
srl sarcalumenin 0.053
gdf6a growth differentiation factor 6a 0.052
tmem38a transmembrane protein 38A 0.052
smyd2a SET and MYND domain containing 2a 0.051
ndrg4 N-myc downstream regulated gene 4 0.049
csrp3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.048
tnnt1 troponin T1, skeletal, slow 0.048
col7a1l collagen type VII alpha 1-like 0.045
synpo2lb synaptopodin 2-like b 0.045
shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.044
gata4 GATA-binding protein 4 0.044
popdc2 popeye domain containing 2 0.042
sema3ab semaphorin 3ab 0.042
rarab retinoic acid receptor, alpha b 0.041
dcaf7 ddb1 and cul4 associated factor 7 0.040
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
vg vestigial 0.013
LanB2 Laminin B2 0.013
mys myospheroid 0.012
sls sallimus 0.012
Cg25C Collagen type IV 0.011
ci cubitus interruptus 0.011
Act88F Actin 88F 0.011
wupA wings up A 0.010
RASSF8 CG5053 gene product from transcript CG5053-RA 0.010
hth homothorax 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
TRIM63 tripartite motif containing 63 0.392
HDAC4 histone deacetylase 4 0.114
COL4A2 collagen, type IV, alpha 2 0.048
COL4A1 collagen, type IV, alpha 1 0.035
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.031
TBX5 T-box 5 0.028
FLNA filamin A, alpha 0.027
CDK2 cyclin-dependent kinase 2 0.024
NRP1 neuropilin 1 0.022
NOTCH3 notch 3 0.022
BMPR1A bone morphogenetic protein receptor, type IA 0.022
ACTN1 actinin, alpha 1 0.020
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.018
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.018
FSTL1 follistatin-like 1 0.018
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.015
HDAC1 histone deacetylase 1 0.012
NOTCH1 notch 1 0.012
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Mus musculus
Name Description Probability Func Analog Organism
Nos3 nitric oxide synthase 3, endothelial cell 0.999
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.997
Hand2 heart and neural crest derivatives expressed transcript 2 0.990
Notch1 Notch gene homolog 1 (Drosophila) 0.974
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.943
Tbx3 T-box 3 0.885
Foxc2 forkhead box C2 0.877
Pitx2 paired-like homeodomain transcription factor 2 0.866
Cox6a2 cytochrome c oxidase, subunit VI a, polypeptide 2 0.858
Myl3 myosin, light polypeptide 3 0.858
Gata4 GATA binding protein 4 0.852
Shh sonic hedgehog 0.849
Flt4 FMS-like tyrosine kinase 4 0.844
Cnn1 calponin 1 0.789
Kdr kinase insert domain protein receptor 0.770
Hand1 heart and neural crest derivatives expressed transcript 1 0.755
Fgf8 fibroblast growth factor 8 0.744
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.693
Sox9 SRY-box containing gene 9 0.659
Bmp4 bone morphogenetic protein 4 0.649
Actc1 actin, alpha, cardiac muscle 1 0.631
Foxc1 forkhead box C1 0.624
Ctnnb1 catenin (cadherin associated protein), beta 1 0.622
Jag1 jagged 1 0.614
Fgfr2 fibroblast growth factor receptor 2 0.607
Hoxa1 homeobox A1 0.598
Efnb2 ephrin B2 0.567
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.551
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.549
Msx1 homeobox, msh-like 1 0.537
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.528
Vegfa vascular endothelial growth factor A 0.523
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.518
Col4a2 collagen, type IV, alpha 2 0.489
Gli3 GLI-Kruppel family member GLI3 0.468
Ldb3 LIM domain binding 3 0.459
Tagln transgelin 0.453
Hspb7 heat shock protein family, member 7 (cardiovascular) 0.450
Fgfr1 fibroblast growth factor receptor 1 0.439
Tbx5 T-box 5 0.434
Bmp7 bone morphogenetic protein 7 0.432
Prrx1 paired related homeobox 1 0.424
Lepr leptin receptor 0.412
Myl9 myosin, light polypeptide 9, regulatory 0.397
Dll4 delta-like 4 (Drosophila) 0.381
Scn5a sodium channel, voltage-gated, type V, alpha 0.379
Dll1 delta-like 1 (Drosophila) 0.379
Nog noggin 0.376
Col4a1 collagen, type IV, alpha 1 0.374
Meox2 mesenchyme homeobox 2 0.373
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.361
Actn2 actinin alpha 2 0.339
Smad6 MAD homolog 6 (Drosophila) 0.339
Otx2 orthodenticle homolog 2 (Drosophila) 0.337
Gata6 GATA binding protein 6 0.333
Eya1 eyes absent 1 homolog (Drosophila) 0.331
Vangl2 vang-like 2 (van gogh, Drosophila) 0.320
Ptch1 patched homolog 1 0.317
Sox2 SRY-box containing gene 2 0.317
Myom2 myomesin 2 0.313
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.311
Dmd dystrophin, muscular dystrophy 0.304
Csf1 colony stimulating factor 1 (macrophage) 0.300
Ptprb protein tyrosine phosphatase, receptor type, B 0.291
Gli2 GLI-Kruppel family member GLI2 0.281
Col1a1 collagen, type I, alpha 1 0.274
Notch2 Notch gene homolog 2 (Drosophila) 0.274
Yap1 yes-associated protein 1 0.269
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.264
Bmpr1a bone morphogenetic protein receptor, type 1A 0.264
Tgfb2 transforming growth factor, beta 2 0.263
Pax3 paired box gene 3 0.257
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.255
Fgfr3 fibroblast growth factor receptor 3 0.255
Des desmin 0.253
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.245
Bmp5 bone morphogenetic protein 5 0.244
Pitx1 paired-like homeodomain transcription factor 1 0.239
Wt1 Wilms tumor 1 homolog 0.228
Sox7 SRY-box containing gene 7 0.224
Hoxa13 homeobox A13 0.217
Fbn2 fibrillin 2 0.212
Xirp1 xin actin-binding repeat containing 1 0.208
Tcf21 transcription factor 21 0.208
Psen1 presenilin 1 0.207
Hrc histidine rich calcium binding protein 0.203
Flnc filamin C, gamma 0.197
She src homology 2 domain-containing transforming protein E 0.194
Adrb1 adrenergic receptor, beta 1 0.192
Tnnt3 troponin T3, skeletal, fast 0.191
Gja5 gap junction protein, alpha 5 0.190
Tbx2 T-box 2 0.190
Wnt5a wingless-related MMTV integration site 5A 0.189
Zeb1 zinc finger E-box binding homeobox 1 0.188
Popdc3 popeye domain containing 3 0.186
Egfl7 EGF-like domain 7 0.185
Actg2 actin, gamma 2, smooth muscle, enteric 0.181
Gja1 gap junction protein, alpha 1 0.177
Chd7 chromodomain helicase DNA binding protein 7 0.176
Cdh5 cadherin 5 0.176
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ahsg alpha-2-HS-glycoprotein 0.304
Cav1 caveolin 1, caveolae protein 0.240
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.135
Ube2c ubiquitin-conjugating enzyme E2C 0.130
LOC100362824 caveolin 2-like 0.113
Apoh apolipoprotein H (beta-2-glycoprotein I) 0.112
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.093
Cav2 caveolin 2 0.091
Alb albumin 0.073
Top2a topoisomerase (DNA) II alpha 0.071
Pttg1 pituitary tumor-transforming 1 0.071
Cdkn3 cyclin-dependent kinase inhibitor 3 0.051
LOC299282 Serine protease inhibitor 0.050
Fga fibrinogen alpha chain 0.048
Cox6a2 cytochrome c oxidase, subunit VIa, polypeptide 2 0.046
Hspb2 heat shock protein beta 2 0.042
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.041
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.037
Lif leukemia inhibitory factor 0.035
Cckar cholecystokinin A receptor 0.034
Ccnb1 cyclin B1 0.032
Nos3 nitric oxide synthase 3, endothelial cell 0.032
Serpina11 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 0.031
Kifc1 kinesin family member C1 0.030
Stmn1 stathmin 1 0.030
LOC286980 putative pheromone receptor (Go-VN13B) 0.029
Casq2 calsequestrin 2 (cardiac muscle) 0.028
Vom2r27 vomeronasal 2 receptor, 27 0.027
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.027
Hspb7 heat shock protein family, member 7 (cardiovascular) 0.026
Spp2 secreted phosphoprotein 2 0.025
Proc protein C 0.025
Emp1 epithelial membrane protein 1 0.025
Agtr1a angiotensin II receptor, type 1a 0.025
Rup2 urinary protein 2 0.025
Mb myoglobin 0.024
Pzp pregnancy-zone protein 0.021
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.021
Grik3 glutamate receptor, ionotropic, kainate 3 0.021
Myoz2 myozenin 2 0.021
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.020
Traf4af1 TRAF4 associated factor 1 0.019
Hpx hemopexin 0.019
Rrm2 ribonucleotide reductase M2 0.019
Capn8 calpain 8 0.019
Tpo thyroid peroxidase 0.019
Smad3 SMAD family member 3 0.019
Nexn nexilin (F actin binding protein) 0.018
Actc1 actin, alpha, cardiac muscle 1 0.018
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.018
LOC689399 hypothetical protein LOC689399 0.018
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.017
Actn2 actinin alpha 2 0.017
Apcs amyloid P component, serum 0.017
Pdha2 pyruvate dehydrogenase (lipoamide) alpha 2 0.017
Tnni1 troponin I type 1 (skeletal, slow) 0.016
Gc group specific component 0.016
Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 0.016
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.016
F2 coagulation factor II (thrombin) 0.016
Prkd3 protein kinase D3 0.016
Fgf16 fibroblast growth factor 16 0.016
Ckm creatine kinase, muscle 0.016
Selp selectin P 0.015
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.015
Tek TEK tyrosine kinase, endothelial 0.015
Cit citron 0.015
Cav3 caveolin 3 0.015
Kif2c kinesin family member 2C 0.015
Wbp2 WW domain binding protein 2 0.015
Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.015
Gpr6 G protein-coupled receptor 6 0.015
Racgap1 Rac GTPase-activating protein 1 0.015
Ddn dendrin 0.014
Pgam2 phosphoglycerate mutase 2 (muscle) 0.014
Ddr2 discoidin domain receptor tyrosine kinase 2 0.014
Klc2 kinesin light chain 2 0.014
Flnc filamin C, gamma 0.014
Neurog1 neurogenin 1 0.014
Opn1sw opsin 1 (cone pigments), short-wave-sensitive 0.014
Wt1 Wilms tumor 1 0.014
Ifnb1 interferon beta 1, fibroblast 0.014
Cks2 CDC28 protein kinase regulatory subunit 2 0.014
Lamc1 laminin, gamma 1 0.013
Pla2g5 phospholipase A2, group V 0.013
Mcm6 minichromosome maintenance complex component 6 0.013
Ccdc124 coiled-coil domain containing 124 0.013
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.013
Cxcr5 chemokine (C-X-C motif) receptor 5 0.013
Serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.013
Slc12a9 solute carrier family 12 (potassium/chloride transporters), member 9 0.012
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 0.012
Col10a1 collagen, type X, alpha 1 0.012
Serpind1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.012
Sdpr serum deprivation response 0.012
Hdgfl1 hepatoma derived growth factor-like 1 0.012
LOC64038 sertolin 0.012
Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon 0.012
Syt8 synaptotagmin VIII 0.012
LOC100363662 6-phosphogluconate dehydrogenase, decarboxylating-like 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism