Process View
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "translesion synthesis"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
mus101 | mutagen-sensitive 101 | 0.819 | ||
rad50 | CG6339 gene product from transcript CG6339-RD | 0.658 | ||
mus205 | mutagen-sensitive 205 | 0.645 | ||
mus308 | mutagen-sensitive 308 | 0.606 | ||
RecQ5 | homolog of RecQ | 0.555 | ||
CG5524 | CG5524 gene product from transcript CG5524-RA | 0.494 | ||
DNApol-eta | CG7143 gene product from transcript CG7143-RA | 0.484 | ||
lok | loki | 0.411 | ||
Mcm3 | Minichromosome maintenance 3 | 0.374 | ||
nbs | CG6754 gene product from transcript CG6754-RC | 0.220 | ||
Brca2 | Breast cancer 2, early onset homolog | 0.162 | ||
mus209 | mutagen-sensitive 209 | 0.117 | Human | |
mi | minus | 0.100 | ||
hay | haywire | 0.094 | ||
mus210 | mutagen-sensitive 210 | 0.093 | ||
mus201 | mutagen-sensitive 201 | 0.078 | ||
mus309 | mutagen-sensitive 309 | 0.072 | ||
spn-A | spindle A | 0.068 | ||
Smc5 | CG32438 gene product from transcript CG32438-RE | 0.061 | ||
Spc105R | Spc105-related | 0.056 | ||
RecQ4 | CG7487 gene product from transcript CG7487-RA | 0.055 | ||
RnrL | Ribonucleoside diphosphate reductase large subunit | 0.050 | ||
mei-9 | meiotic 9 | 0.049 | ||
dmt | dalmatian | 0.040 | ||
CG5290 | CG5290 gene product from transcript CG5290-RA | 0.036 | ||
dpa | disc proliferation abnormal | 0.031 | ||
mre11 | meiotic recombination 11 | 0.029 | ||
mus304 | mutagen-sensitive 304 | 0.028 | ||
ncd | non-claret disjunctional | 0.027 | ||
CDC45L | CG3658 gene product from transcript CG3658-RA | 0.026 | ||
Irbp | Inverted repeat-binding protein | 0.024 | ||
CG5931 | CG5931 gene product from transcript CG5931-RA | 0.020 | ||
wds | will die slowly | 0.020 | ||
Chrac-14 | CG13399 gene product from transcript CG13399-RA | 0.019 | ||
Lig4 | Ligase4 | 0.016 | ||
Ercc1 | CG10215 gene product from transcript CG10215-RA | 0.015 | ||
l(1)G0095 | lethal (1) G0095 | 0.015 | ||
CG3065 | CG3065 gene product from transcript CG3065-RA | 0.015 | ||
lid | little imaginal discs | 0.015 | ||
Rev1 | CG12189 gene product from transcript CG12189-RA | 0.014 | Yeast Mouse | |
Orc2 | Origin recognition complex subunit 2 | 0.014 | ||
CG9576 | CG9576 gene product from transcript CG9576-RA | 0.014 | ||
Cap-G | CG34438 gene product from transcript CG34438-RF | 0.014 | ||
okr | okra | 0.013 | ||
spn-B | spindle B | 0.013 | ||
stwl | stonewall | 0.013 | ||
su(Hw) | suppressor of Hairy wing | 0.013 | ||
CG12155 | CG12155 gene product from transcript CG12155-RA | 0.012 | ||
Mes2 | CG11100 gene product from transcript CG11100-RB | 0.012 | ||
Orc5 | Origin recognition complex subunit 5 | 0.012 | ||
CG10809 | CG10809 gene product from transcript CG10809-RA | 0.012 | ||
phr | photorepair | 0.012 |