IMP

Process View

Homo sapiens

4 genes annotated in human

regulation of protein deubiquitination

Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein deubiquitination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of protein deubiquitination" (in gray)

Name	Description	Probability	Func Analog Organism
HSPA8	heat shock 70kDa protein 8	0.833
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.741
MED15	mediator complex subunit 15	0.656
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.433
TRIM39	tripartite motif containing 39	0.298	Human
ZNF263	zinc finger protein 263	0.225
DTX1	deltex homolog 1 (Drosophila)	0.212
HDAC11	histone deacetylase 11	0.208
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.193
NSFL1C	NSFL1 (p97) cofactor (p47)	0.136
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.122
SP100	SP100 nuclear antigen	0.104
TRIM17	tripartite motif containing 17	0.099	Human
SNX18	sorting nexin 18	0.096
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.089
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.083
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.080
SOD1	superoxide dismutase 1, soluble	0.072
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.072
DAXX	death-domain associated protein	0.069
SNX9	sorting nexin 9	0.063
ERN1	endoplasmic reticulum to nucleus signaling 1	0.058
SELS	selenoprotein S	0.054
FADD	Fas (TNFRSF6)-associated via death domain	0.052
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.051
TRIM5	tripartite motif containing 5	0.049	Human
TRIM8	tripartite motif containing 8	0.049
ZNF473	zinc finger protein 473	0.047
TRIM21	tripartite motif containing 21	0.045
TRIM34	tripartite motif containing 34	0.045
TRIM43	tripartite motif containing 43	0.045
SAMD9	sterile alpha motif domain containing 9	0.043
TRIM41	tripartite motif containing 41	0.041	Human
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.039
AMFR	autocrine motility factor receptor	0.039
BAG2	BCL2-associated athanogene 2	0.037
TRIM35	tripartite motif containing 35	0.036
DERL1	Der1-like domain family, member 1	0.033
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.031
TRIM52	tripartite motif containing 52	0.029
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.029
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.029
SMAD1	SMAD family member 1	0.028
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.026
MCOLN1	mucolipin 1	0.026
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.024
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.024
SREBF1	sterol regulatory element binding transcription factor 1	0.023
XIAP	X-linked inhibitor of apoptosis	0.023
CYLD	cylindromatosis (turban tumor syndrome)	0.022
TRIM32	tripartite motif containing 32	0.022
ATXN3	ataxin 3	0.021
TRIM26	tripartite motif containing 26	0.021
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.020
WASL	Wiskott-Aldrich syndrome-like	0.020
MKRN3	makorin ring finger protein 3	0.019
IFI16	interferon, gamma-inducible protein 16	0.019
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.019
SYNJ1	synaptojanin 1	0.018
BAG1	BCL2-associated athanogene	0.018
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.018
TRIM6	tripartite motif containing 6	0.018	Human
CTSO	cathepsin O	0.017
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.017
SNX33	sorting nexin 33	0.017
RNF114	ring finger protein 114	0.017
ZNF202	zinc finger protein 202	0.017
KRT18	keratin 18	0.017
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.016
MR1	major histocompatibility complex, class I-related	0.016
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.016
HDAC1	histone deacetylase 1	0.016
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.016
CTSS	cathepsin S	0.015
RNF31	ring finger protein 31	0.015
ZNRF1	zinc and ring finger 1	0.015
ZBTB8A	zinc finger and BTB domain containing 8A	0.015
PSEN2	presenilin 2 (Alzheimer disease 4)	0.015
TRIM25	tripartite motif containing 25	0.015
TRIM4	tripartite motif containing 4	0.014	Human
UBTD1	ubiquitin domain containing 1	0.014
CHD4	chromodomain helicase DNA binding protein 4	0.014
IRF2	interferon regulatory factor 2	0.014
ANXA1	annexin A1	0.014
SMAD3	SMAD family member 3	0.014
FAS	Fas (TNF receptor superfamily, member 6)	0.014
PSEN1	presenilin 1	0.014
RNF126	ring finger protein 126	0.013
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.013
VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	0.013
SMAD4	SMAD family member 4	0.013
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.013
RNF5	ring finger protein 5	0.012
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.012
PLCD4	phospholipase C, delta 4	0.012
TP73	tumor protein p73	0.012
TRIM22	tripartite motif containing 22	0.012	Human
RNF166	ring finger protein 166	0.012
MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	0.012
NMI	N-myc (and STAT) interactor	0.012
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.011
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.011
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.011
DNM2	dynamin 2	0.011
E4F1	E4F transcription factor 1	0.011
RMND5B	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.011
ARIH2	ariadne homolog 2 (Drosophila)	0.010
DYNLL1	dynein, light chain, LC8-type 1	0.010
SNX1	sorting nexin 1	0.010
ZBTB48	zinc finger and BTB domain containing 48	0.010
ADAM15	ADAM metallopeptidase domain 15	0.010
WWOX	WW domain containing oxidoreductase	0.010
NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	0.010