IMP

Process View

Homo sapiens

1 genes annotated in human

otic vesicle development

The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "otic vesicle development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "otic vesicle development" (in gray)

Name	Description	Probability	Func Analog Organism
FGF1	fibroblast growth factor 1 (acidic)	0.817
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.620
SMAD1	SMAD family member 1	0.567
VEGFA	vascular endothelial growth factor A	0.402
SMAD3	SMAD family member 3	0.348
FGF10	fibroblast growth factor 10	0.317
HNF4A	hepatocyte nuclear factor 4, alpha	0.283
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.261
TTN	titin	0.161
COL1A1	collagen, type I, alpha 1	0.144
BMP1	bone morphogenetic protein 1	0.120
NKX2-1	NK2 homeobox 1	0.115
SMAD4	SMAD family member 4	0.103
FGF7	fibroblast growth factor 7	0.095
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.092
COL5A1	collagen, type V, alpha 1	0.071
SMAD7	SMAD family member 7	0.069
ADAM12	ADAM metallopeptidase domain 12	0.067
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.065
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.058
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.053
SH3BP4	SH3-domain binding protein 4	0.052
ZNF148	zinc finger protein 148	0.051
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.050
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.049
MSX2	msh homeobox 2	0.044
PDPK1	3-phosphoinositide dependent protein kinase-1	0.044
BBS1	Bardet-Biedl syndrome 1	0.038
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.036
SUPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	0.036
KCTD1	potassium channel tetramerisation domain containing 1	0.033
FSTL1	follistatin-like 1	0.033
COL1A2	collagen, type I, alpha 2	0.033
PAX2	paired box 2	0.029	Human
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.028
TRIM63	tripartite motif containing 63	0.028
FGFR1	fibroblast growth factor receptor 1	0.026
HIPK2	homeodomain interacting protein kinase 2	0.026
GRB7	growth factor receptor-bound protein 7	0.024
HRG	histidine-rich glycoprotein	0.023
MTMR10	myotubularin related protein 10	0.023
CTGF	connective tissue growth factor	0.023
SIM2	single-minded homolog 2 (Drosophila)	0.022
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.022
RAD54L2	RAD54-like 2 (S. cerevisiae)	0.022
SPIN1	spindlin 1	0.022
DNAJB14	DnaJ (Hsp40) homolog, subfamily B, member 14	0.022
TNPO1	transportin 1	0.021
CXXC5	CXXC finger protein 5	0.021
ANKRD13A	ankyrin repeat domain 13A	0.021
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.021
MEST	mesoderm specific transcript homolog (mouse)	0.021
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.021
RNF11	ring finger protein 11	0.021
HNF1A	HNF1 homeobox A	0.020
DLX2	distal-less homeobox 2	0.019
TRAF4	TNF receptor-associated factor 4	0.019
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.019
RBM17	RNA binding motif protein 17	0.019
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.019
SKIL	SKI-like oncogene	0.018
ZMYM2	zinc finger, MYM-type 2	0.018
COL2A1	collagen, type II, alpha 1	0.018	Mouse
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.018
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.018
SOX7	SRY (sex determining region Y)-box 7	0.018
THAP2	THAP domain containing, apoptosis associated protein 2	0.017
EYA2	eyes absent homolog 2 (Drosophila)	0.017
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.017
PGF	placental growth factor	0.017
COL3A1	collagen, type III, alpha 1	0.016
SP1	Sp1 transcription factor	0.016
SMAD9	SMAD family member 9	0.015
HOXA11	homeobox A11	0.015
RBM4	RNA binding motif protein 4	0.015
LHX2	LIM homeobox 2	0.015
ACTN2	actinin, alpha 2	0.014
HNF1B	HNF1 homeobox B	0.014	Zebrafish
PAX3	paired box 3	0.014
GATA2	GATA binding protein 2	0.014
WNT7A	wingless-type MMTV integration site family, member 7A	0.014
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.014
ATF7IP	activating transcription factor 7 interacting protein	0.014
SIX3	SIX homeobox 3	0.013
PRRC1	proline-rich coiled-coil 1	0.013
DACH1	dachshund homolog 1 (Drosophila)	0.013
INHBA	inhibin, beta A	0.013
OVOL1	ovo-like 1(Drosophila)	0.013
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.013
SMAD6	SMAD family member 6	0.013
HOXC8	homeobox C8	0.013
DLX4	distal-less homeobox 4	0.013	Zebrafish
HMGA2	high mobility group AT-hook 2	0.013
PAX7	paired box 7	0.013
CDX2	caudal type homeobox 2	0.013
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.012
HYAL1	hyaluronoglucosaminidase 1	0.012
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.012
NLK	nemo-like kinase	0.012
SMAD2	SMAD family member 2	0.012
SOX5	SRY (sex determining region Y)-box 5	0.012
HOXD13	homeobox D13	0.012
MYOZ1	myozenin 1	0.012
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.012
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.012
HOXD9	homeobox D9	0.012
ZBED5	zinc finger, BED-type containing 5	0.012
WT1	Wilms tumor 1	0.012
POU4F1	POU class 4 homeobox 1	0.012
EYA1	eyes absent homolog 1 (Drosophila)	0.012
LYPD3	LY6/PLAUR domain containing 3	0.012
LBX1	ladybird homeobox 1	0.012
PAX8	paired box 8	0.012
HOXD11	homeobox D11	0.012
FGFR3	fibroblast growth factor receptor 3	0.011
BCAT1	branched chain amino-acid transaminase 1, cytosolic	0.011
CHD8	chromodomain helicase DNA binding protein 8	0.011
SCAMP1	secretory carrier membrane protein 1	0.011
SMG5	Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.011
MYOZ2	myozenin 2	0.011
TAL1	T-cell acute lymphocytic leukemia 1	0.011
ZNF579	zinc finger protein 579	0.011
WWOX	WW domain containing oxidoreductase	0.011
HEMGN	hemogen	0.011
FGF18	fibroblast growth factor 18	0.011
SIX2	SIX homeobox 2	0.011
PRRC2A	proline-rich coiled-coil 2A	0.011
LTK	leukocyte receptor tyrosine kinase	0.011
ONECUT2	one cut homeobox 2	0.011
DAXX	death-domain associated protein	0.011
RUNX2	runt-related transcription factor 2	0.011
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.011
TBX1	T-box 1	0.011
OTP	orthopedia homeobox	0.011
HOXB7	homeobox B7	0.011
LHX1	LIM homeobox 1	0.010
FOXC1	forkhead box C1	0.010
FGF8	fibroblast growth factor 8 (androgen-induced)	0.010
CLCNKB	chloride channel Kb	0.010
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.010
STC2	stanniocalcin 2	0.010
CHERP	calcium homeostasis endoplasmic reticulum protein	0.010
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.010
PYY	peptide YY	0.010
TNS3	tensin 3	0.010
RND3	Rho family GTPase 3	0.010
EPAS1	endothelial PAS domain protein 1	0.010
ONECUT1	one cut homeobox 1	0.010