IMP

Process View

Homo sapiens

19 genes annotated in human

oxidoreduction coenzyme metabolic process

The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "oxidoreduction coenzyme metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "oxidoreduction coenzyme metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.997	Yeast
ALDOA	aldolase A, fructose-bisphosphate	0.883
TPI1	triosephosphate isomerase 1	0.753
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.734	Yeast
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.623
PGK1	phosphoglycerate kinase 1	0.579
ENO1	enolase 1, (alpha)	0.577
TKT	transketolase	0.504
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.497	Yeast
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.494	Yeast
GPI	glucose-6-phosphate isomerase	0.489
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.345	Yeast
LDHA	lactate dehydrogenase A	0.318
ZFYVE9	zinc finger, FYVE domain containing 9	0.290
SLC25A11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	0.245
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.243	Rat
FBXL15	F-box and leucine-rich repeat protein 15	0.198
IDH3G	isocitrate dehydrogenase 3 (NAD+) gamma	0.183	Rat
ND1	NADH dehydrogenase, subunit 1 (complex I)	0.173
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.172	Yeast
PKM2	pyruvate kinase, muscle	0.161
ANKRD13A	ankyrin repeat domain 13A	0.130
UQCRC1	ubiquinol-cytochrome c reductase core protein I	0.112
AGXT2	alanine--glyoxylate aminotransferase 2	0.107
HIGD2A	HIG1 hypoxia inducible domain family, member 2A	0.099
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.097	Yeast
BBS1	Bardet-Biedl syndrome 1	0.090
ECHS1	enoyl CoA hydratase, short chain, 1, mitochondrial	0.090
ING2	inhibitor of growth family, member 2	0.075
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.069
SMAD4	SMAD family member 4	0.066
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.063
RHOA	ras homolog gene family, member A	0.061
CXXC5	CXXC finger protein 5	0.061
C9orf16	chromosome 9 open reading frame 16	0.060
FTL	ferritin, light polypeptide	0.058
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.055
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	0.054
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.051
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.050
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.050
G6PD	glucose-6-phosphate dehydrogenase	0.048
SMAD5	SMAD family member 5	0.046
ACO2	aconitase 2, mitochondrial	0.046
PPIF	peptidylprolyl isomerase F	0.045
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.042
VDAC1	voltage-dependent anion channel 1	0.039
POU5F1	POU class 5 homeobox 1	0.037
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.036
GLA	galactosidase, alpha	0.035
TALDO1	transaldolase 1	0.035
DTX1	deltex homolog 1 (Drosophila)	0.033
FTH1	ferritin, heavy polypeptide 1	0.033
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.032
TRAF4	TNF receptor-associated factor 4	0.031
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.030
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.029
LOC729020	rcRPE	0.029
BBS2	Bardet-Biedl syndrome 2	0.029
RNF168	ring finger protein 168	0.028
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.027
PGD	phosphogluconate dehydrogenase	0.026
MDH2	malate dehydrogenase 2, NAD (mitochondrial)	0.024
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.024
CCDC127	coiled-coil domain containing 127	0.024
SNX9	sorting nexin 9	0.023
CYC1	cytochrome c-1	0.022
GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)	0.022
SUCLA2	succinate-CoA ligase, ADP-forming, beta subunit	0.022
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.022
GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	0.022
GCDH	glutaryl-CoA dehydrogenase	0.022
IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.021
ATP5D	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	0.021
FLII	flightless I homolog (Drosophila)	0.020
BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide	0.020
PEMT	phosphatidylethanolamine N-methyltransferase	0.020
ZFAND5	zinc finger, AN1-type domain 5	0.020
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.020
BBS4	Bardet-Biedl syndrome 4	0.020
SMAD7	SMAD family member 7	0.020
GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	0.019
BBS7	Bardet-Biedl syndrome 7	0.019
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.019
ECHDC1	enoyl CoA hydratase domain containing 1	0.019
CDT1	chromatin licensing and DNA replication factor 1	0.019
OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	0.018	Rat
CAV1	caveolin 1, caveolae protein, 22kDa	0.018
WDR13	WD repeat domain 13	0.017
POR	P450 (cytochrome) oxidoreductase	0.016
GCKR	glucokinase (hexokinase 4) regulator	0.016
SOX7	SRY (sex determining region Y)-box 7	0.016
PTN	pleiotrophin	0.016
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.015
SMAD1	SMAD family member 1	0.015
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.015
TXN2	thioredoxin 2	0.015
TSPO	translocator protein (18kDa)	0.015
ALAS1	aminolevulinate, delta-, synthase 1	0.015
CAPNS1	calpain, small subunit 1	0.014
POLH	polymerase (DNA directed), eta	0.014
FMO3	flavin containing monooxygenase 3	0.014	Human
ING1	inhibitor of growth family, member 1	0.014
SCAND1	SCAN domain containing 1	0.013
CSNK1D	casein kinase 1, delta	0.013
XIAP	X-linked inhibitor of apoptosis	0.013
ECI1	enoyl-CoA delta isomerase 1	0.013
PHGDH	phosphoglycerate dehydrogenase	0.013
TST	thiosulfate sulfurtransferase (rhodanese)	0.013
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.013
ZEB2	zinc finger E-box binding homeobox 2	0.013
ADARB1	adenosine deaminase, RNA-specific, B1	0.013
QRSL1	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	0.012
MYO6	myosin VI	0.012
C2orf18	chromosome 2 open reading frame 18	0.012
DGAT1	diacylglycerol O-acyltransferase 1	0.012
MRPL35	mitochondrial ribosomal protein L35	0.012
PFKL	phosphofructokinase, liver	0.011
ARRDC3	arrestin domain containing 3	0.011
AGPS	alkylglycerone phosphate synthase	0.011
RAB1B	RAB1B, member RAS oncogene family	0.011
APEH	N-acylaminoacyl-peptide hydrolase	0.011
KLF5	Kruppel-like factor 5 (intestinal)	0.011
GCH1	GTP cyclohydrolase 1	0.011
FOXD3	forkhead box D3	0.011
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.011
UBAC1	UBA domain containing 1	0.011
EPAS1	endothelial PAS domain protein 1	0.011
DLST	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.011	Rat
BID	BH3 interacting domain death agonist	0.011
MTCH2	mitochondrial carrier homolog 2 (C. elegans)	0.011
AK2	adenylate kinase 2	0.011
NEK3	NIMA (never in mitosis gene a)-related kinase 3	0.011
GYS1	glycogen synthase 1 (muscle)	0.010
SH3KBP1	SH3-domain kinase binding protein 1	0.010
DIDO1	death inducer-obliterator 1	0.010
NDFIP2	Nedd4 family interacting protein 2	0.010
HSPB1	heat shock 27kDa protein 1	0.010
CARS	cysteinyl-tRNA synthetase	0.010