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Homo sapiens

29 genes annotated in human

developmental disorder of mental health

DOID:0060037

A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psycholotgical or physical development.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "developmental disorder of mental health"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "developmental disorder of mental health" (in gray)

Name	Description	Probability	Func Analog Organism
EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3	0.292
MAPK1	mitogen-activated protein kinase 1	0.246
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.227
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.214
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.205
CHD7	chromodomain helicase DNA binding protein 7	0.178	Human
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.137
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.121
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.099	Human
ETF1	eukaryotic translation termination factor 1	0.098
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.096	Human
MAPK6	mitogen-activated protein kinase 6	0.094
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.092
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.084
HIPK2	homeodomain interacting protein kinase 2	0.074
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.068
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.067	Human
WBP11	WW domain binding protein 11	0.066
SMS	spermine synthase	0.062
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.060
RPL8	ribosomal protein L8	0.056
EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2	0.055
SH2D1A	SH2 domain containing 1A	0.045
AMD1	adenosylmethionine decarboxylase 1	0.045
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.040
RBBP5	retinoblastoma binding protein 5	0.035
DNM2	dynamin 2	0.035
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.033
RPTOR	regulatory associated protein of MTOR, complex 1	0.029
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.028
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.028
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.028
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	0.027
TMEM108	transmembrane protein 108	0.026
MAP2K1	mitogen-activated protein kinase kinase 1	0.026
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.026
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.026	Human
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.026
WBP2	WW domain binding protein 2	0.026
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.025
PEA15	phosphoprotein enriched in astrocytes 15	0.025
POMP	proteasome maturation protein	0.024
IQGAP1	IQ motif containing GTPase activating protein 1	0.024
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.024
RAB1A	RAB1A, member RAS oncogene family	0.024
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.024
BZW1	basic leucine zipper and W2 domains 1	0.024
CTTN	cortactin	0.023
MFSD10	major facilitator superfamily domain containing 10	0.023
RPL36	ribosomal protein L36	0.022
HIST1H2BF	histone cluster 1, H2bf	0.021
ITSN1	intersectin 1 (SH3 domain protein)	0.021
NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit	0.020
UBA1	ubiquitin-like modifier activating enzyme 1	0.020
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.019
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.019
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.019
ARF1	ADP-ribosylation factor 1	0.019
DUSP3	dual specificity phosphatase 3	0.018
LYPLA1	lysophospholipase I	0.018
MAPK14	mitogen-activated protein kinase 14	0.018
NTF3	neurotrophin 3	0.017	Human
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.017
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.017
SPRR2A	small proline-rich protein 2A	0.017
SMN2	survival of motor neuron 2, centromeric	0.017
TRIP10	thyroid hormone receptor interactor 10	0.016
C14orf1	chromosome 14 open reading frame 1	0.016
RAB24	RAB24, member RAS oncogene family	0.016
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.015
DSE	dermatan sulfate epimerase	0.015
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.015
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.015
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.015
IDH3G	isocitrate dehydrogenase 3 (NAD+) gamma	0.015
RAP2C	RAP2C, member of RAS oncogene family	0.014
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.014
C1D	C1D nuclear receptor corepressor	0.014
CAB39	calcium binding protein 39	0.014
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.014
RPL23A	ribosomal protein L23a	0.014
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.014
EIF4A1	eukaryotic translation initiation factor 4A1	0.013
KCTD13	potassium channel tetramerisation domain containing 13	0.013
ATP13A3	ATPase type 13A3	0.013
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.013
AQR	aquarius homolog (mouse)	0.013
UBA2	ubiquitin-like modifier activating enzyme 2	0.013
BRD2	bromodomain containing 2	0.013
ZBTB4	zinc finger and BTB domain containing 4	0.013
PTPRR	protein tyrosine phosphatase, receptor type, R	0.013
DLG2	discs, large homolog 2 (Drosophila)	0.012
MAPT	microtubule-associated protein tau	0.012
PGK1	phosphoglycerate kinase 1	0.012
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.012
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.012
MBNL1	muscleblind-like (Drosophila)	0.012
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.012
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.012
GSPT1	G1 to S phase transition 1	0.012
WSB2	WD repeat and SOCS box containing 2	0.012
KDM2A	lysine (K)-specific demethylase 2A	0.012
CYCS	cytochrome c, somatic	0.011
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.011
SART1	squamous cell carcinoma antigen recognized by T cells	0.011
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.011
GAA	glucosidase, alpha; acid	0.011
ING2	inhibitor of growth family, member 2	0.011
TSR2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)	0.011
GNL1	guanine nucleotide binding protein-like 1	0.011
NLK	nemo-like kinase	0.011
FAM50A	family with sequence similarity 50, member A	0.011
EIF5	eukaryotic translation initiation factor 5	0.011
TMOD3	tropomodulin 3 (ubiquitous)	0.011
SLMO2	slowmo homolog 2 (Drosophila)	0.011
PICALM	phosphatidylinositol binding clathrin assembly protein	0.011
PHF1	PHD finger protein 1	0.011
B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	0.011
RPS5	ribosomal protein S5	0.011
MYO1E	myosin IE	0.011
PTP4A1	protein tyrosine phosphatase type IVA, member 1	0.010
NRXN1	neurexin 1	0.010
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.010
SEC24C	SEC24 family, member C (S. cerevisiae)	0.010
GCLM	glutamate-cysteine ligase, modifier subunit	0.010
TYK2	tyrosine kinase 2	0.010
RPL3	ribosomal protein L3	0.010
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	0.010
IL1RAPL1	interleukin 1 receptor accessory protein-like 1	0.007
CNTNAP2	contactin associated protein-like 2	0.006
OPHN1	oligophrenin 1	0.005
TSPAN7	tetraspanin 7	0.005
TMLHE	trimethyllysine hydroxylase, epsilon	0.005
GDI1	GDP dissociation inhibitor 1	0.005
NLGN4X	neuroligin 4, X-linked	0.005
SLITRK1	SLIT and NTRK-like family, member 1	0.005
ACSL4	acyl-CoA synthetase long-chain family member 4	0.005
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.005
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.005
BDNF	brain-derived neurotrophic factor	0.005
TPH2	tryptophan hydroxylase 2	0.004
FOXG1	forkhead box G1	0.004
HDC	histidine decarboxylase	0.004
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.004
TRAPPC9	trafficking protein particle complex 9	0.004
RPL10	ribosomal protein L10	0.004
NLGN3	neuroligin 3	0.004
DRD4	dopamine receptor D4	0.003
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.003
DRD5	dopamine receptor D5	0.003
CHD8	chromodomain helicase DNA binding protein 8	0.002
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.002
EIF4E	eukaryotic translation initiation factor 4E	0.002
MAN1B1	mannosidase, alpha, class 1B, member 1	0.002
PQBP1	polyglutamine binding protein 1	0.001