IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

regulation of myelination

GO:0031641

Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of myelination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of myelination" (in gray)

Name	Description	Probability	Func Analog Organism
MED25	mediator complex subunit 25	0.965
NCOA1	nuclear receptor coactivator 1	0.943
TRAF2	TNF receptor-associated factor 2	0.829
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.808	Mouse
RARA	retinoic acid receptor, alpha	0.708	Rat
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.525
RXRB	retinoid X receptor, beta	0.351	Rat
NCOA3	nuclear receptor coactivator 3	0.326
RICTOR	RPTOR independent companion of MTOR, complex 2	0.285
ADAM17	ADAM metallopeptidase domain 17	0.277
BTRC	beta-transducin repeat containing	0.246
JUP	junction plakoglobin	0.203
CREBBP	CREB binding protein	0.193
NCOR2	nuclear receptor corepressor 2	0.189
SPOP	speckle-type POZ protein	0.183
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.168
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.167
YAP1	Yes-associated protein 1	0.163
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.163
TRAF5	TNF receptor-associated factor 5	0.152
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.115
HIC1	hypermethylated in cancer 1	0.109
PSEN1	presenilin 1	0.107
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.103
F11R	F11 receptor	0.102
CDH5	cadherin 5, type 2 (vascular endothelium)	0.100
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.098
APC	adenomatous polyposis coli	0.093
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.093
GLIS2	GLIS family zinc finger 2	0.089
TCF4	transcription factor 4	0.086
TRADD	TNFRSF1A-associated via death domain	0.079
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.077
RPTOR	regulatory associated protein of MTOR, complex 1	0.076
PRKCI	protein kinase C, iota	0.068
GAST	gastrin	0.061
TRAF3	TNF receptor-associated factor 3	0.058
JAM3	junctional adhesion molecule 3	0.057
STMN2	stathmin-like 2	0.056
RXRA	retinoid X receptor, alpha	0.052	Rat
GSK3B	glycogen synthase kinase 3 beta	0.050
TRAF1	TNF receptor-associated factor 1	0.046
JAM2	junctional adhesion molecule 2	0.045
KIAA1377	KIAA1377	0.044
TNF	tumor necrosis factor	0.043
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.042
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.041
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.041
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.036	Mouse
CTNNBIP1	catenin, beta interacting protein 1	0.035
TTR	transthyretin	0.035
C16orf53	chromosome 16 open reading frame 53	0.033
NCOA2	nuclear receptor coactivator 2	0.032
NGF	nerve growth factor (beta polypeptide)	0.031
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.029
DEPTOR	DEP domain containing MTOR-interacting protein	0.029
PRKCZ	protein kinase C, zeta	0.028
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.028
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.028
RHEBL1	Ras homolog enriched in brain like 1	0.028
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.027
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.027
AXIN1	axin 1	0.027
AR	androgen receptor	0.027
CD14	CD14 molecule	0.026
AKT1S1	AKT1 substrate 1 (proline-rich)	0.024
APP	amyloid beta (A4) precursor protein	0.024
DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.024
SALL2	sal-like 2 (Drosophila)	0.023
STX11	syntaxin 11	0.023
EMD	emerin	0.022
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.022
ACVR1B	activin A receptor, type IB	0.022
PML	promyelocytic leukemia	0.022
SORBS3	sorbin and SH3 domain containing 3	0.022
KIF13B	kinesin family member 13B	0.021
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.021
KANK2	KN motif and ankyrin repeat domains 2	0.021
PDPK1	3-phosphoinositide dependent protein kinase-1	0.021
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.021
STAT5A	signal transducer and activator of transcription 5A	0.020
HDAC11	histone deacetylase 11	0.020
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.020
BAD	BCL2-associated agonist of cell death	0.019
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.019	Human
A2M	alpha-2-macroglobulin	0.019
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.019
DCTN1	dynactin 1	0.018
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.018
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.018
FOXO1	forkhead box O1	0.018
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.016
HR	hairless homolog (mouse)	0.016
CD40	CD40 molecule, TNF receptor superfamily member 5	0.016	Human
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.016
CD80	CD80 molecule	0.016
LRP6	low density lipoprotein receptor-related protein 6	0.016
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.015
SNAP23	synaptosomal-associated protein, 23kDa	0.015
FBXW11	F-box and WD repeat domain containing 11	0.015
PNMA2	paraneoplastic antigen MA2	0.015
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015	Mouse
TIFA	TRAF-interacting protein with forkhead-associated domain	0.015
RHEB	Ras homolog enriched in brain	0.015
TRAF3IP2	TRAF3 interacting protein 2	0.014
NRIP1	nuclear receptor interacting protein 1	0.014
LAMC3	laminin, gamma 3	0.014
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.014
PTK7	PTK7 protein tyrosine kinase 7	0.014
ZNF576	zinc finger protein 576	0.013
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.013
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.013
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.013
NCOA6	nuclear receptor coactivator 6	0.013
ASXL1	additional sex combs like 1 (Drosophila)	0.013
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.013
IRAK2	interleukin-1 receptor-associated kinase 2	0.013
PEBP4	phosphatidylethanolamine-binding protein 4	0.012
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.012
RNF5	ring finger protein 5	0.012
THEM4	thioesterase superfamily member 4	0.012
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.012
TYMP	thymidine phosphorylase	0.012
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.012
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.012
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.012	Human
RTKN	rhotekin	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
PBK	PDZ binding kinase	0.012
TNRC6A	trinucleotide repeat containing 6A	0.011
HFE	hemochromatosis	0.011
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
HDAC6	histone deacetylase 6	0.011
ZBTB48	zinc finger and BTB domain containing 48	0.011
ADRB2	adrenergic, beta-2-, receptor, surface	0.011
CRYAB	crystallin, alpha B	0.011
MED1	mediator complex subunit 1	0.011
CHGB	chromogranin B (secretogranin 1)	0.010
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.010
FAM129A	family with sequence similarity 129, member A	0.010
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.010
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.010
SETDB1	SET domain, bifurcated 1	0.010
TJP1	tight junction protein 1 (zona occludens 1)	0.010
LIN7A	lin-7 homolog A (C. elegans)	0.010
JUB	jub, ajuba homolog (Xenopus laevis)	0.010