IMP

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Homo sapiens

3 genes annotated in human

Multi-species View

positive regulation of interleukin 5 production

GO:0032754

Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of interleukin 5 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of interleukin 5 production" (in gray)

Name	Description	Probability	Func Analog Organism
RXRA	retinoid X receptor, alpha	1.000
MED25	mediator complex subunit 25	1.000
TAL1	T-cell acute lymphocytic leukemia 1	1.000
NCOA1	nuclear receptor coactivator 1	1.000
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.999
RARA	retinoic acid receptor, alpha	0.991
PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	0.985
NCOR2	nuclear receptor corepressor 2	0.979
ZNF71	zinc finger protein 71	0.925
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.923
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.880
RXRB	retinoid X receptor, beta	0.877
CCDC115	coiled-coil domain containing 115	0.870
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.843
NUMB	numb homolog (Drosophila)	0.803
PPARA	peroxisome proliferator-activated receptor alpha	0.801
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.773
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.718
NMT2	N-myristoyltransferase 2	0.681
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.572
MED1	mediator complex subunit 1	0.539
TBX5	T-box 5	0.462
RXRG	retinoid X receptor, gamma	0.454
KANK2	KN motif and ankyrin repeat domains 2	0.413
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.350
F11R	F11 receptor	0.249
KLF13	Kruppel-like factor 13	0.243
PRKD2	protein kinase D2	0.224
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.218
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.211
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.201
TRIM32	tripartite motif containing 32	0.201
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.198
RUNX1	runt-related transcription factor 1	0.197
PDPK1	3-phosphoinositide dependent protein kinase-1	0.193
SORBS3	sorbin and SH3 domain containing 3	0.178
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.163	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.155
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.131
BCL3	B-cell CLL/lymphoma 3	0.115
CREBBP	CREB binding protein	0.111
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.109
PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	0.102
ZFPM1	zinc finger protein, multitype 1	0.101
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.097
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.096
ESR1	estrogen receptor 1	0.094
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.087
LMO2	LIM domain only 2 (rhombotin-like 1)	0.086
GATA2	GATA binding protein 2	0.085	Human
NCOA6	nuclear receptor coactivator 6	0.078
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.078
PGR	progesterone receptor	0.076
NR2F6	nuclear receptor subfamily 2, group F, member 6	0.074
NCOA3	nuclear receptor coactivator 3	0.066
FOXJ1	forkhead box J1	0.064
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.064
PRKCI	protein kinase C, iota	0.063
LRRK2	leucine-rich repeat kinase 2	0.057
DENND5A	DENN/MADD domain containing 5A	0.056
NCOR1	nuclear receptor corepressor 1	0.054
CREM	cAMP responsive element modulator	0.054
STK4	serine/threonine kinase 4	0.050
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.048
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.047
ADAP1	ArfGAP with dual PH domains 1	0.044
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.043
AMHR2	anti-Mullerian hormone receptor, type II	0.042
TADA3	transcriptional adaptor 3	0.042
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.041
ASXL1	additional sex combs like 1 (Drosophila)	0.041
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.041
PDE4D	phosphodiesterase 4D, cAMP-specific	0.041
WWC1	WW and C2 domain containing 1	0.040
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.037	Human
SPOP	speckle-type POZ protein	0.037
PDE4B	phosphodiesterase 4B, cAMP-specific	0.037	Human
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.037
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.037
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.036
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.035
KLF1	Kruppel-like factor 1 (erythroid)	0.035
ACVR1B	activin A receptor, type IB	0.034
PPARG	peroxisome proliferator-activated receptor gamma	0.034
THEM4	thioesterase superfamily member 4	0.033
NR1D1	nuclear receptor subfamily 1, group D, member 1	0.033	Human
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.033
ZBTB16	zinc finger and BTB domain containing 16	0.033
HR	hairless homolog (mouse)	0.033
PDE7B	phosphodiesterase 7B	0.031	Human
ZNF576	zinc finger protein 576	0.030
NPAS2	neuronal PAS domain protein 2	0.030
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.029
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.028
MAPK7	mitogen-activated protein kinase 7	0.028
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.027
SPIN1	spindlin 1	0.027
SPHK1	sphingosine kinase 1	0.026
GATA4	GATA binding protein 4	0.026	Human
DHH	desert hedgehog	0.025
PNRC1	proline-rich nuclear receptor coactivator 1	0.024
HDAC3	histone deacetylase 3	0.023
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.022	Human
GATA5	GATA binding protein 5	0.022	Human
LNX1	ligand of numb-protein X 1	0.022
ACY3	aspartoacylase (aminocyclase) 3	0.022
RARG	retinoic acid receptor, gamma	0.021	Human
DAB2IP	DAB2 interacting protein	0.021
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.021
ALX4	ALX homeobox 4	0.020
PTPRU	protein tyrosine phosphatase, receptor type, U	0.020
CRABP2	cellular retinoic acid binding protein 2	0.020
HDC	histidine decarboxylase	0.020
ZBTB38	zinc finger and BTB domain containing 38	0.019
PAWR	PRKC, apoptosis, WT1, regulator	0.019
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.019
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.018
SOX18	SRY (sex determining region Y)-box 18	0.018
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.018
PNMT	phenylethanolamine N-methyltransferase	0.018
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.018
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.018
HOXB9	homeobox B9	0.018
FAM129A	family with sequence similarity 129, member A	0.018
IL24	interleukin 24	0.018
MED29	mediator complex subunit 29	0.018
MBNL2	muscleblind-like 2 (Drosophila)	0.017
ZMYND11	zinc finger, MYND-type containing 11	0.017
RTKN	rhotekin	0.017
SERGEF	secretion regulating guanine nucleotide exchange factor	0.017
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.017
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.017
MAP2K5	mitogen-activated protein kinase kinase 5	0.016
CTSE	cathepsin E	0.016
BAD	BCL2-associated agonist of cell death	0.016
SOCS7	suppressor of cytokine signaling 7	0.016
ATXN1L	ataxin 1-like	0.016
PRKCQ	protein kinase C, theta	0.016
BHLHE23	basic helix-loop-helix family, member e23	0.016
CPA3	carboxypeptidase A3 (mast cell)	0.016
DLG5	discs, large homolog 5 (Drosophila)	0.016
PEBP4	phosphatidylethanolamine-binding protein 4	0.015
THSD4	thrombospondin, type I, domain containing 4	0.015
HIC1	hypermethylated in cancer 1	0.015
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.015
PDE3A	phosphodiesterase 3A, cGMP-inhibited	0.015
LSR	lipolysis stimulated lipoprotein receptor	0.015
ZFPM2	zinc finger protein, multitype 2	0.015
PAX9	paired box 9	0.014
RGS1	regulator of G-protein signaling 1	0.014
RORA	RAR-related orphan receptor A	0.014
LYL1	lymphoblastic leukemia derived sequence 1	0.014
DLC1	deleted in liver cancer 1	0.014
SOCS1	suppressor of cytokine signaling 1	0.014
EYA4	eyes absent homolog 4 (Drosophila)	0.014
CLDN11	claudin 11	0.014
SFRP5	secreted frizzled-related protein 5	0.014
NTF3	neurotrophin 3	0.014
EFNB1	ephrin-B1	0.014
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.014
STAC	SH3 and cysteine rich domain	0.014
AKAP6	A kinase (PRKA) anchor protein 6	0.014
ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	0.013
CLCF1	cardiotrophin-like cytokine factor 1	0.013
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.013
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.013
DIO3	deiodinase, iodothyronine, type III	0.013
ANK1	ankyrin 1, erythrocytic	0.013
TBX1	T-box 1	0.013
WT1	Wilms tumor 1	0.013
AKAP12	A kinase (PRKA) anchor protein 12	0.013
PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	0.013
VTN	vitronectin	0.013
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.013
NR3C2	nuclear receptor subfamily 3, group C, member 2	0.013
MS4A2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.013
DUSP4	dual specificity phosphatase 4	0.012
HOXC5	homeobox C5	0.012
ZFHX4	zinc finger homeobox 4	0.012
GFI1B	growth factor independent 1B transcription repressor	0.012
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.012
RARB	retinoic acid receptor, beta	0.012	Human
GYPB	glycophorin B (MNS blood group)	0.012
RAB30	RAB30, member RAS oncogene family	0.012
ETV1	ets variant 1	0.012
SFRP1	secreted frizzled-related protein 1	0.012
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.012
ESRRG	estrogen-related receptor gamma	0.012
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.012
INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	0.012
PAX5	paired box 5	0.012
AVPR1A	arginine vasopressin receptor 1A	0.012
SORBS2	sorbin and SH3 domain containing 2	0.012
FHL1	four and a half LIM domains 1	0.012
BDNF	brain-derived neurotrophic factor	0.012
SIRT6	sirtuin 6	0.012
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.012
LIFR	leukemia inhibitory factor receptor alpha	0.012
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.012
RBMS3	RNA binding motif, single stranded interacting protein 3	0.012
MED26	mediator complex subunit 26	0.012
APOA4	apolipoprotein A-IV	0.012
FHIT	fragile histidine triad gene	0.012
ALS2	amyotrophic lateral sclerosis 2 (juvenile)	0.012
GP9	glycoprotein IX (platelet)	0.011
ZBTB7A	zinc finger and BTB domain containing 7A	0.011
BMP6	bone morphogenetic protein 6	0.011
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.011
DACH1	dachshund homolog 1 (Drosophila)	0.011
CD69	CD69 molecule	0.011
C5orf41	chromosome 5 open reading frame 41	0.011
AFTPH	aftiphilin	0.011
TFR2	transferrin receptor 2	0.011
PRKG2	protein kinase, cGMP-dependent, type II	0.011
MEF2A	myocyte enhancer factor 2A	0.011
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.011
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.011
CYP4F22	cytochrome P450, family 4, subfamily F, polypeptide 22	0.011
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.011
CAPN5	calpain 5	0.011
PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	0.011
KEL	Kell blood group, metallo-endopeptidase	0.011
SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	0.010
FYCO1	FYVE and coiled-coil domain containing 1	0.010
ATF7	activating transcription factor 7	0.010
HOXC8	homeobox C8	0.010
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.010
HMGA2	high mobility group AT-hook 2	0.010
CISH	cytokine inducible SH2-containing protein	0.010
RGS16	regulator of G-protein signaling 16	0.010
HDAC10	histone deacetylase 10	0.010
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.010
HDAC7	histone deacetylase 7	0.010
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.010
RNF152	ring finger protein 152	0.010
CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	0.010
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.010
FHOD3	formin homology 2 domain containing 3	0.010
ACVR2A	activin A receptor, type IIA	0.010
TBX3	T-box 3	0.010
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.010
GDNF	glial cell derived neurotrophic factor	0.010
F2RL2	coagulation factor II (thrombin) receptor-like 2	0.010
SOX13	SRY (sex determining region Y)-box 13	0.010
ZDHHC17	zinc finger, DHHC-type containing 17	0.010
ARID5B	AT rich interactive domain 5B (MRF1-like)	0.010
ZBED5	zinc finger, BED-type containing 5	0.010
NLK	nemo-like kinase	0.010
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.010
NPAS1	neuronal PAS domain protein 1	0.010
WNT11	wingless-type MMTV integration site family, member 11	0.010
RHAG	Rh-associated glycoprotein	0.010
NRP2	neuropilin 2	0.010
PF4	platelet factor 4	0.010