IMP

Process View

Homo sapiens

15 genes annotated in human

retina development in camera type eye

The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retina development in camera type eye"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "retina development in camera type eye" (in gray)

Name	Description	Probability	Func Analog Organism
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.712
SMAD3	SMAD family member 3	0.583
HDAC2	histone deacetylase 2	0.491
RBBP4	retinoblastoma binding protein 4	0.291
HDAC1	histone deacetylase 1	0.284	Zebrafish
ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	0.238
PBX1	pre-B-cell leukemia homeobox 1	0.214
ZFYVE9	zinc finger, FYVE domain containing 9	0.184
VEGFA	vascular endothelial growth factor A	0.178
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.168
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.168
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.154
NCOR2	nuclear receptor corepressor 2	0.140
CTSA	cathepsin A	0.129
C2orf65	chromosome 2 open reading frame 65	0.122
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.115
COL4A1	collagen, type IV, alpha 1	0.113
GRN	granulin	0.098
PSAP	prosaposin	0.090
COL4A2	collagen, type IV, alpha 2	0.084	Human
NFYA	nuclear transcription factor Y, alpha	0.081
EP300	E1A binding protein p300	0.074
CTBP1	C-terminal binding protein 1	0.072
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.067	Human
SKIL	SKI-like oncogene	0.064
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.060
PML	promyelocytic leukemia	0.057
PLD3	phospholipase D family, member 3	0.055
RUVBL1	RuvB-like 1 (E. coli)	0.055
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.053	Zebrafish
SFPQ	splicing factor proline/glutamine-rich	0.053
WNT3A	wingless-type MMTV integration site family, member 3A	0.052
INADL	InaD-like (Drosophila)	0.052
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.048	Zebrafish
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.047	Zebrafish
CREBBP	CREB binding protein	0.046
NKX2-1	NK2 homeobox 1	0.043
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.042
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.042
RUNX1	runt-related transcription factor 1	0.042
HNF4A	hepatocyte nuclear factor 4, alpha	0.040
RBBP7	retinoblastoma binding protein 7	0.040
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.039
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.037
CDK9	cyclin-dependent kinase 9	0.037
COL4A4	collagen, type IV, alpha 4	0.037	Human
EGFR	epidermal growth factor receptor	0.036
TAL1	T-cell acute lymphocytic leukemia 1	0.034	Human
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.034
NCOR1	nuclear receptor corepressor 1	0.034
CHD7	chromodomain helicase DNA binding protein 7	0.034
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.032
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.032
NOSTRIN	nitric oxide synthase trafficker	0.031
PLCG1	phospholipase C, gamma 1	0.031
CAPNS1	calpain, small subunit 1	0.031
CAV1	caveolin 1, caveolae protein, 22kDa	0.030
FYN	FYN oncogene related to SRC, FGR, YES	0.029
MYBBP1A	MYB binding protein (P160) 1a	0.029
MYOD1	myogenic differentiation 1	0.029
TCF12	transcription factor 12	0.027
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.027
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.026
CBX1	chromobox homolog 1	0.026
GSK3B	glycogen synthase kinase 3 beta	0.026
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.025
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.025
EED	embryonic ectoderm development	0.025
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.025
HIC1	hypermethylated in cancer 1	0.025
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.024
RFC3	replication factor C (activator 1) 3, 38kDa	0.024
GATA4	GATA binding protein 4	0.024
ZCCHC17	zinc finger, CCHC domain containing 17	0.023
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.023
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.023
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.023	Mouse
CTBP2	C-terminal binding protein 2	0.023
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.023
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.022
CALCA	calcitonin-related polypeptide alpha	0.022
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.021
SOX11	SRY (sex determining region Y)-box 11	0.021
GABARAP	GABA(A) receptor-associated protein	0.020
SIX6	SIX homeobox 6	0.020	Zebrafish
BMI1	BMI1 polycomb ring finger oncogene	0.020
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.020
BBS4	Bardet-Biedl syndrome 4	0.020
PVRL4	poliovirus receptor-related 4	0.020
ZNF512B	zinc finger protein 512B	0.020
HIST1H3B	histone cluster 1, H3b	0.020
CSNK1G1	casein kinase 1, gamma 1	0.019
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.019	Zebrafish
PRKG1	protein kinase, cGMP-dependent, type I	0.019
PTCH1	patched 1	0.019
TDG	thymine-DNA glycosylase	0.019
PCDH9	protocadherin 9	0.018
NEUROD1	neurogenic differentiation 1	0.018	Human Mouse
MEIS2	Meis homeobox 2	0.018
CTSB	cathepsin B	0.018
SETD8	SET domain containing (lysine methyltransferase) 8	0.018
COL4A6	collagen, type IV, alpha 6	0.018	Human
PTEN	phosphatase and tensin homolog	0.017
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.017
PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.017
ADAM15	ADAM metallopeptidase domain 15	0.017
BAK1	BCL2-antagonist/killer 1	0.017
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.017
PVRL3	poliovirus receptor-related 3	0.017	Mouse
BBS7	Bardet-Biedl syndrome 7	0.017
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.017
COL4A5	collagen, type IV, alpha 5	0.016	Human
ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	0.016
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.016
BCAR1	breast cancer anti-estrogen resistance 1	0.016
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.016
GDF5	growth differentiation factor 5	0.015
PCNA	proliferating cell nuclear antigen	0.015
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.015
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.015
APC	adenomatous polyposis coli	0.015	Mouse
AR	androgen receptor	0.015
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.015
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.015
TIMP2	TIMP metallopeptidase inhibitor 2	0.015
PTK2	PTK2 protein tyrosine kinase 2	0.014
EPAS1	endothelial PAS domain protein 1	0.014
YY1	YY1 transcription factor	0.014
YAP1	Yes-associated protein 1	0.014
NID1	nidogen 1	0.014
RBBP5	retinoblastoma binding protein 5	0.014
LRP1	low density lipoprotein receptor-related protein 1	0.014	Human
CTCF	CCCTC-binding factor (zinc finger protein)	0.014
HOXA9	homeobox A9	0.014
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.014
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.014
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.014
CLN3	ceroid-lipofuscinosis, neuronal 3	0.013
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.013
CHD8	chromodomain helicase DNA binding protein 8	0.013	Human
HOXD12	homeobox D12	0.013
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.013
GLB1	galactosidase, beta 1	0.013
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.013
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.012
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.012	Mouse
PAX6	paired box 6	0.012	Zebrafish Mouse Rat
SMAD2	SMAD family member 2	0.012
RFC4	replication factor C (activator 1) 4, 37kDa	0.012
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.012
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.012
SIX3	SIX homeobox 3	0.012
NDP	Norrie disease (pseudoglioma)	0.012
FOXD3	forkhead box D3	0.012
FOXA2	forkhead box A2	0.012
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.012
SOX2	SRY (sex determining region Y)-box 2	0.012	Mouse
ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	0.012	Zebrafish
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
BRCA1	breast cancer 1, early onset	0.011
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.011
ELF5	E74-like factor 5 (ets domain transcription factor)	0.011
POU5F1	POU class 5 homeobox 1	0.011
TK1	thymidine kinase 1, soluble	0.011
SOX1	SRY (sex determining region Y)-box 1	0.011
CAPRIN2	caprin family member 2	0.011
DNM1	dynamin 1	0.011
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.011	Human
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.011
SEC31A	SEC31 homolog A (S. cerevisiae)	0.011
CDH5	cadherin 5, type 2 (vascular endothelium)	0.011
CDK6	cyclin-dependent kinase 6	0.011
TGFB3	transforming growth factor, beta 3	0.011
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.010
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.010
PPARA	peroxisome proliferator-activated receptor alpha	0.010
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.010
SAP30	Sin3A-associated protein, 30kDa	0.010
CHERP	calcium homeostasis endoplasmic reticulum protein	0.010
BRD4	bromodomain containing 4	0.010
RBM10	RNA binding motif protein 10	0.010
PRIM1	primase, DNA, polypeptide 1 (49kDa)	0.010