IMP

Process View

Homo sapiens

2 genes annotated in human

paramesonephric duct development

The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.

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Gene Predictions

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Name	Description	Probability	Func Analog Organism
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.970
FGF18	fibroblast growth factor 18	0.961
WNT1	wingless-type MMTV integration site family, member 1	0.945	Human
PAX8	paired box 8	0.862
WNT7A	wingless-type MMTV integration site family, member 7A	0.681	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.482
WNT3	wingless-type MMTV integration site family, member 3	0.478	Human
AQP5	aquaporin 5	0.446
IHH	Indian hedgehog	0.412
WIF1	WNT inhibitory factor 1	0.410
BBS1	Bardet-Biedl syndrome 1	0.371
WNT4	wingless-type MMTV integration site family, member 4	0.329
HES2	hairy and enhancer of split 2 (Drosophila)	0.308
WNT11	wingless-type MMTV integration site family, member 11	0.303	Human
PRRX2	paired related homeobox 2	0.302
LBX1	ladybird homeobox 1	0.288
FGF3	fibroblast growth factor 3	0.258
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.239
FIBCD1	fibrinogen C domain containing 1	0.213
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.212
BBS4	Bardet-Biedl syndrome 4	0.197
BHLHE23	basic helix-loop-helix family, member e23	0.186
OTP	orthopedia homeobox	0.183
SFRP1	secreted frizzled-related protein 1	0.166
HOXA11	homeobox A11	0.162
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.153
FOXD3	forkhead box D3	0.151
ADAMTSL2	ADAMTS-like 2	0.133
FOXN4	forkhead box N4	0.126
SOX21	SRY (sex determining region Y)-box 21	0.125
NPAS1	neuronal PAS domain protein 1	0.123
HMX1	H6 family homeobox 1	0.120
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.114
HOXB1	homeobox B1	0.112
ADRA1D	adrenergic, alpha-1D-, receptor	0.103
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.098
FOXB1	forkhead box B1	0.097
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.096
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.094
RAX	retina and anterior neural fold homeobox	0.093
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.090
DLX4	distal-less homeobox 4	0.089
LHX3	LIM homeobox 3	0.089
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.088
CRLF1	cytokine receptor-like factor 1	0.086
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.085
JPH3	junctophilin 3	0.085
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.078
HOXD13	homeobox D13	0.075
FOXL1	forkhead box L1	0.074
SOX1	SRY (sex determining region Y)-box 1	0.072
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.072
COL2A1	collagen, type II, alpha 1	0.071
NKX2-1	NK2 homeobox 1	0.070
NKD1	naked cuticle homolog 1 (Drosophila)	0.068
VSX1	visual system homeobox 1	0.067
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.065
NOVA2	neuro-oncological ventral antigen 2	0.064
HOXB8	homeobox B8	0.064
PAX1	paired box 1	0.064
NEUROD2	neurogenic differentiation 2	0.063
HR	hairless homolog (mouse)	0.062
HOXC12	homeobox C12	0.062
TLX3	T-cell leukemia homeobox 3	0.062
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.061
COL6A1	collagen, type VI, alpha 1	0.059
INSM2	insulinoma-associated 2	0.058
HOXD11	homeobox D11	0.058
POU3F3	POU class 3 homeobox 3	0.057
GDNF	glial cell derived neurotrophic factor	0.056
OTOP2	otopetrin 2	0.055
ARTN	artemin	0.054
HOXC5	homeobox C5	0.053
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.052
NCR2	natural cytotoxicity triggering receptor 2	0.051
WNT9B	wingless-type MMTV integration site family, member 9B	0.051	Human
WNT10B	wingless-type MMTV integration site family, member 10B	0.051	Human
GSX2	GS homeobox 2	0.051
CRABP2	cellular retinoic acid binding protein 2	0.050
NEUROG2	neurogenin 2	0.050
HOXD9	homeobox D9	0.050
OLIG2	oligodendrocyte lineage transcription factor 2	0.049
GBX2	gastrulation brain homeobox 2	0.048
HOXD10	homeobox D10	0.045
KREMEN2	kringle containing transmembrane protein 2	0.045
GJA3	gap junction protein, alpha 3, 46kDa	0.044
NKX6-1	NK6 homeobox 1	0.044
FOXF2	forkhead box F2	0.043
RSPO1	R-spondin homolog (Xenopus laevis)	0.043
NKX2-8	NK2 homeobox 8	0.043
WNT7B	wingless-type MMTV integration site family, member 7B	0.042	Human
PAX3	paired box 3	0.042
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.041
POU3F1	POU class 3 homeobox 1	0.041
SFRP5	secreted frizzled-related protein 5	0.040
EPHB2	EPH receptor B2	0.040
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.039
LMX1B	LIM homeobox transcription factor 1, beta	0.039
SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.039
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.038
SYT12	synaptotagmin XII	0.038
FGFR4	fibroblast growth factor receptor 4	0.038
BBS7	Bardet-Biedl syndrome 7	0.037
NXPH4	neurexophilin 4	0.036
A4GALT	alpha 1,4-galactosyltransferase	0.035
PAX7	paired box 7	0.035
WT1	Wilms tumor 1	0.035
PLXDC1	plexin domain containing 1	0.034
COL13A1	collagen, type XIII, alpha 1	0.034
MMP25	matrix metallopeptidase 25	0.033
KLK7	kallikrein-related peptidase 7	0.033
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.032
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.032
OCA2	oculocutaneous albinism II	0.032
NXNL2	nucleoredoxin-like 2	0.032
KCNK9	potassium channel, subfamily K, member 9	0.031
TLX2	T-cell leukemia homeobox 2	0.031
NKX3-2	NK3 homeobox 2	0.031
S1PR5	sphingosine-1-phosphate receptor 5	0.031
C1QL1	complement component 1, q subcomponent-like 1	0.030
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.030
WNT6	wingless-type MMTV integration site family, member 6	0.030	Human
CDX1	caudal type homeobox 1	0.030
CHRD	chordin	0.029
SIM2	single-minded homolog 2 (Drosophila)	0.029
EVPL	envoplakin	0.029
HOXB13	homeobox B13	0.029
GGN	gametogenetin	0.029
ADAMTSL5	ADAMTS-like 5	0.029
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.028
OVOL1	ovo-like 1(Drosophila)	0.028
TRPV4	transient receptor potential cation channel, subfamily V, member 4	0.028
PITX1	paired-like homeodomain 1	0.027
PLCH2	phospholipase C, eta 2	0.027
CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.027
GSC2	goosecoid homeobox 2	0.026
SIX3	SIX homeobox 3	0.026
FOXL2	forkhead box L2	0.026
FGF22	fibroblast growth factor 22	0.026
LMX1A	LIM homeobox transcription factor 1, alpha	0.026
OTX2	orthodenticle homeobox 2	0.025
ALDOB	aldolase B, fructose-bisphosphate	0.025
CLCNKB	chloride channel Kb	0.025
IRX4	iroquois homeobox 4	0.025
FGF4	fibroblast growth factor 4	0.025
MNX1	motor neuron and pancreas homeobox 1	0.025
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.024
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.024
DLX1	distal-less homeobox 1	0.024
HMX2	H6 family homeobox 2	0.024
HOXD1	homeobox D1	0.024
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.024
INSL3	insulin-like 3 (Leydig cell)	0.024
ESPN	espin	0.024
COL4A6	collagen, type IV, alpha 6	0.024
PROM2	prominin 2	0.024
NKD2	naked cuticle homolog 2 (Drosophila)	0.023
FERD3L	Fer3-like (Drosophila)	0.023
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.023
WNT2B	wingless-type MMTV integration site family, member 2B	0.023	Human
TTC22	tetratricopeptide repeat domain 22	0.023
FOXH1	forkhead box H1	0.023
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.023
LBP	lipopolysaccharide binding protein	0.023
DRD4	dopamine receptor D4	0.023
BMP4	bone morphogenetic protein 4	0.023
KCNK4	potassium channel, subfamily K, member 4	0.022
MMP17	matrix metallopeptidase 17 (membrane-inserted)	0.022
TLX1	T-cell leukemia homeobox 1	0.022
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.022
DUOX1	dual oxidase 1	0.022
CALCA	calcitonin-related polypeptide alpha	0.022
KLHL35	kelch-like 35 (Drosophila)	0.021
CARD10	caspase recruitment domain family, member 10	0.021
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.021
AHSG	alpha-2-HS-glycoprotein	0.021
CCDC48	coiled-coil domain containing 48	0.021
KCNK15	potassium channel, subfamily K, member 15	0.021
VSTM2L	V-set and transmembrane domain containing 2 like	0.021
DLL4	delta-like 4 (Drosophila)	0.021
GRIK3	glutamate receptor, ionotropic, kainate 3	0.021
AMN	amnionless homolog (mouse)	0.020
NTN1	netrin 1	0.020
EMX1	empty spiracles homeobox 1	0.020
GPR20	G protein-coupled receptor 20	0.020
BMP7	bone morphogenetic protein 7	0.020
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.020
GLIS1	GLIS family zinc finger 1	0.020
ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2	0.020
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.020
TACR1	tachykinin receptor 1	0.020
HRH3	histamine receptor H3	0.020
SLC7A4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4	0.019
TH	tyrosine hydroxylase	0.019
SMTNL2	smoothelin-like 2	0.019
LMO1	LIM domain only 1 (rhombotin 1)	0.019
TCL1B	T-cell leukemia/lymphoma 1B	0.019
CRB3	crumbs homolog 3 (Drosophila)	0.019
COMP	cartilage oligomeric matrix protein	0.019
FZD10	frizzled homolog 10 (Drosophila)	0.019
CDX2	caudal type homeobox 2	0.019
EPHB3	EPH receptor B3	0.019
FOXA2	forkhead box A2	0.019
CDH16	cadherin 16, KSP-cadherin	0.018
HCRTR1	hypocretin (orexin) receptor 1	0.018
TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	0.018
FGF17	fibroblast growth factor 17	0.018
EXOC3L2	exocyst complex component 3-like 2	0.018
NECAB2	N-terminal EF-hand calcium binding protein 2	0.018
GRP	gastrin-releasing peptide	0.017
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.017
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.017
PYY	peptide YY	0.017
PSPN	persephin	0.017
VEGFC	vascular endothelial growth factor C	0.017
HNF1A	HNF1 homeobox A	0.017
TBX5	T-box 5	0.017
ALX4	ALX homeobox 4	0.017
KLK10	kallikrein-related peptidase 10	0.017
POU4F3	POU class 4 homeobox 3	0.017
EPS8L1	EPS8-like 1	0.017
NOTUM	notum pectinacetylesterase homolog (Drosophila)	0.017
FOXF1	forkhead box F1	0.017
FEZF2	FEZ family zinc finger 2	0.017
TG	thyroglobulin	0.017
EPHA8	EPH receptor A8	0.017
RGS9BP	regulator of G protein signaling 9 binding protein	0.016
ICOSLG	inducible T-cell co-stimulator ligand	0.016
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.016
BFSP1	beaded filament structural protein 1, filensin	0.016
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.016
EFNA3	ephrin-A3	0.016
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.016
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.016
COL4A4	collagen, type IV, alpha 4	0.016
CD70	CD70 molecule	0.016
BARX1	BARX homeobox 1	0.016
ALX3	ALX homeobox 3	0.016
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.016
PRDM13	PR domain containing 13	0.016
PRSS22	protease, serine, 22	0.016
IL11	interleukin 11	0.016
UTF1	undifferentiated embryonic cell transcription factor 1	0.016
FZD8	frizzled homolog 8 (Drosophila)	0.016
WNT10A	wingless-type MMTV integration site family, member 10A	0.015	Human
TNK1	tyrosine kinase, non-receptor, 1	0.015
TSGA10IP	testis specific, 10 interacting protein	0.015
BNC1	basonuclin 1	0.015
DLX3	distal-less homeobox 3	0.015
USH1G	Usher syndrome 1G (autosomal recessive)	0.015
PTH2	parathyroid hormone 2	0.015
MMP19	matrix metallopeptidase 19	0.015
NTN3	netrin 3	0.015
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.015
SCARF2	scavenger receptor class F, member 2	0.015
GATA5	GATA binding protein 5	0.015
EYA2	eyes absent homolog 2 (Drosophila)	0.015
FGF19	fibroblast growth factor 19	0.015
ADRA2B	adrenergic, alpha-2B-, receptor	0.014
EDN2	endothelin 2	0.014
EN2	engrailed homeobox 2	0.014
MAST1	microtubule associated serine/threonine kinase 1	0.014
PAX5	paired box 5	0.014
GALR2	galanin receptor 2	0.014
FGD1	FYVE, RhoGEF and PH domain containing 1	0.014
RSPO4	R-spondin family, member 4	0.014
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	0.014
GSTT1	glutathione S-transferase theta 1	0.014
CPNE9	copine family member IX	0.014
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.014
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.014
CDHR1	cadherin-related family member 1	0.014
NPPC	natriuretic peptide C	0.014
GLI2	GLI family zinc finger 2	0.014
NT5C1A	5'-nucleotidase, cytosolic IA	0.014
PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	0.014
HES7	hairy and enhancer of split 7 (Drosophila)	0.014
LPAR3	lysophosphatidic acid receptor 3	0.014
RASL10A	RAS-like, family 10, member A	0.014
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.014
C2CD4C	C2 calcium-dependent domain containing 4C	0.014
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.014
HOXA4	homeobox A4	0.014
CX3CL1	chemokine (C-X3-C motif) ligand 1	0.014
KRT13	keratin 13	0.014
LHX4	LIM homeobox 4	0.014
NANOS3	nanos homolog 3 (Drosophila)	0.014
ASIP	agouti signaling protein	0.014
CRABP1	cellular retinoic acid binding protein 1	0.013
PRMT8	protein arginine methyltransferase 8	0.013
UNC93A	unc-93 homolog A (C. elegans)	0.013
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.013
SFTPD	surfactant protein D	0.013
DUSP15	dual specificity phosphatase 15	0.013
CST1	cystatin SN	0.013
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.013
KISS1	KiSS-1 metastasis-suppressor	0.013
OPRD1	opioid receptor, delta 1	0.013
HOXD3	homeobox D3	0.013
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.013
SHH	sonic hedgehog	0.013
CD6	CD6 molecule	0.013
SMO	smoothened homolog (Drosophila)	0.013
SP5	Sp5 transcription factor	0.013
FOXD2	forkhead box D2	0.013
ADRA1B	adrenergic, alpha-1B-, receptor	0.013
INHBB	inhibin, beta B	0.013
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.013
GNRH2	gonadotropin-releasing hormone 2	0.013
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.013
SIX2	SIX homeobox 2	0.013
CRHR1	corticotropin releasing hormone receptor 1	0.013
NKPD1	NTPase, KAP family P-loop domain containing 1	0.013
UPB1	ureidopropionase, beta	0.013
RARG	retinoic acid receptor, gamma	0.013
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.013
TMEM132E	transmembrane protein 132E	0.013
TKTL1	transketolase-like 1	0.012
PAEP	progestagen-associated endometrial protein	0.012
GJB5	gap junction protein, beta 5, 31.1kDa	0.012
DLEU7	deleted in lymphocytic leukemia, 7	0.012
HOXC10	homeobox C10	0.012
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.012
SLITRK5	SLIT and NTRK-like family, member 5	0.012
SPTBN4	spectrin, beta, non-erythrocytic 4	0.012
CST4	cystatin S	0.012
BARHL1	BarH-like homeobox 1	0.012
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.012
EMX2	empty spiracles homeobox 2	0.012
ADRA2C	adrenergic, alpha-2C-, receptor	0.012
COL19A1	collagen, type XIX, alpha 1	0.012
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.012
TLL2	tolloid-like 2	0.012
FAM163B	family with sequence similarity 163, member B	0.012
HYAL1	hyaluronoglucosaminidase 1	0.012
LHX2	LIM homeobox 2	0.012
RPRML	reprimo-like	0.012
CCNO	cyclin O	0.012
GPR143	G protein-coupled receptor 143	0.012
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.012
HOXB9	homeobox B9	0.012
PITX2	paired-like homeodomain 2	0.012
GYLTL1B	glycosyltransferase-like 1B	0.012
ARSI	arylsulfatase family, member I	0.012
RHOD	ras homolog gene family, member D	0.011
BBS2	Bardet-Biedl syndrome 2	0.011
EN1	engrailed homeobox 1	0.011
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.011
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.011
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.011
FRMPD1	FERM and PDZ domain containing 1	0.011
RTN4R	reticulon 4 receptor	0.011
MSI1	musashi homolog 1 (Drosophila)	0.011
REM1	RAS (RAD and GEM)-like GTP-binding 1	0.011
HOXB4	homeobox B4	0.011
NXPH3	neurexophilin 3	0.011
COL9A3	collagen, type IX, alpha 3	0.011
WSCD2	WSC domain containing 2	0.011
SYT11	synaptotagmin XI	0.011
DOK7	docking protein 7	0.011
SNX22	sorting nexin 22	0.011
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.011
GALNT9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)	0.011
HNF1B	HNF1 homeobox B	0.011
EFNA2	ephrin-A2	0.011
PNMT	phenylethanolamine N-methyltransferase	0.011
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.011
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.011
DNAJC22	DnaJ (Hsp40) homolog, subfamily C, member 22	0.011
S100A3	S100 calcium binding protein A3	0.011
DMRT3	doublesex and mab-3 related transcription factor 3	0.011
PODNL1	podocan-like 1	0.011
LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.011
HPSE2	heparanase 2	0.011
CCBE1	collagen and calcium binding EGF domains 1	0.011
HOXB5	homeobox B5	0.011
TRIM67	tripartite motif containing 67	0.010
DLL3	delta-like 3 (Drosophila)	0.010
OSR1	odd-skipped related 1 (Drosophila)	0.010
PHOX2A	paired-like homeobox 2a	0.010
LAMA1	laminin, alpha 1	0.010
CCDC102A	coiled-coil domain containing 102A	0.010
GSC	goosecoid homeobox	0.010
GPR6	G protein-coupled receptor 6	0.010
PTK7	PTK7 protein tyrosine kinase 7	0.010
LAMA5	laminin, alpha 5	0.010
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.010
HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	0.010
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.010
EID3	EP300 interacting inhibitor of differentiation 3	0.010
LTK	leukocyte receptor tyrosine kinase	0.010
IL4	interleukin 4	0.010