IMP

Process View

Homo sapiens

25 genes annotated in human

positive regulation of hormone secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of hormone secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of hormone secretion" (in gray)

Name	Description	Probability	Func Analog Organism
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.970
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.946
C1QA	complement component 1, q subcomponent, A chain	0.932	Human
TEK	TEK tyrosine kinase, endothelial	0.829
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.723
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.681
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.577	Human
INSR	insulin receptor	0.575
FGA	fibrinogen alpha chain	0.558
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.494
SNAP23	synaptosomal-associated protein, 23kDa	0.494
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.470
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.412
HCK	hemopoietic cell kinase	0.384	Human
FGB	fibrinogen beta chain	0.383
IGF1R	insulin-like growth factor 1 receptor	0.333
HLA-DMB	major histocompatibility complex, class II, DM beta	0.312
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.273
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.200
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.194
HNF4A	hepatocyte nuclear factor 4, alpha	0.170
GRB10	growth factor receptor-bound protein 10	0.160
GRB2	growth factor receptor-bound protein 2	0.160
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.146
CAPNS1	calpain, small subunit 1	0.146
BLNK	B-cell linker	0.145
GRB7	growth factor receptor-bound protein 7	0.140
FGG	fibrinogen gamma chain	0.140
PSEN2	presenilin 2 (Alzheimer disease 4)	0.131
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.129
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.127	Human
C1QC	complement component 1, q subcomponent, C chain	0.125	Human
CLASP1	cytoplasmic linker associated protein 1	0.122
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.119
SNAP25	synaptosomal-associated protein, 25kDa	0.117
SYK	spleen tyrosine kinase	0.099
GOLGA2	golgin A2	0.092
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.085
C1QB	complement component 1, q subcomponent, B chain	0.081	Human
TTR	transthyretin	0.070
CRHR1	corticotropin releasing hormone receptor 1	0.065
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.065
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.064
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.062
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.060
WIPF1	WAS/WASL interacting protein family, member 1	0.058
ADORA2A	adenosine A2a receptor	0.057
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.054
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.054
IRS1	insulin receptor substrate 1	0.043	Rat
SH2B1	SH2B adaptor protein 1	0.041
SPDEF	SAM pointed domain containing ets transcription factor	0.036
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.036
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.034
SMAD2	SMAD family member 2	0.033
APOA1	apolipoprotein A-I	0.033
MARCO	macrophage receptor with collagenous structure	0.031
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.031
NCK1	NCK adaptor protein 1	0.029
ESRRG	estrogen-related receptor gamma	0.029
IRF2	interferon regulatory factor 2	0.028
SSTR3	somatostatin receptor 3	0.028	Human
YY1	YY1 transcription factor	0.026
RUSC2	RUN and SH3 domain containing 2	0.026
NSF	N-ethylmaleimide-sensitive factor	0.025
GLIS2	GLIS family zinc finger 2	0.024
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.024	Human
HIPK2	homeodomain interacting protein kinase 2	0.024
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.023
MYO6	myosin VI	0.023
CREBBP	CREB binding protein	0.022
HIC1	hypermethylated in cancer 1	0.021
JAK1	Janus kinase 1	0.020
SSTR2	somatostatin receptor 2	0.020	Human
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.020	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.020
BCR	breakpoint cluster region	0.020
PLCG1	phospholipase C, gamma 1	0.019
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.019
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.019
GNMT	glycine N-methyltransferase	0.018
MAPK10	mitogen-activated protein kinase 10	0.018
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.018
OCRL	oculocerebrorenal syndrome of Lowe	0.018
GAS7	growth arrest-specific 7	0.018
LAT	linker for activation of T cells	0.018
FYN	FYN oncogene related to SRC, FGR, YES	0.018	Human
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.017
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.017
STAT5B	signal transducer and activator of transcription 5B	0.017
DRD2	dopamine receptor D2	0.017	Mouse
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.017
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.017
EGFR	epidermal growth factor receptor	0.016
ITK	IL2-inducible T-cell kinase	0.016
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.016
GCKR	glucokinase (hexokinase 4) regulator	0.016
SVOP	SV2 related protein homolog (rat)	0.016
CCK	cholecystokinin	0.016
STAT5A	signal transducer and activator of transcription 5A	0.015
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.015
GLUD2	glutamate dehydrogenase 2	0.015	Human Mouse
F2	coagulation factor II (thrombin)	0.015
SOCS1	suppressor of cytokine signaling 1	0.015
EP300	E1A binding protein p300	0.015
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.015
PDPK1	3-phosphoinositide dependent protein kinase-1	0.015
MPDZ	multiple PDZ domain protein	0.014
KAT2B	K(lysine) acetyltransferase 2B	0.014
NCOA6	nuclear receptor coactivator 6	0.014
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.014
RFK	riboflavin kinase	0.014
SST	somatostatin	0.014
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	0.014
BTK	Bruton agammaglobulinemia tyrosine kinase	0.014	Human
NCOA1	nuclear receptor coactivator 1	0.014
LTK	leukocyte receptor tyrosine kinase	0.014
CDK17	cyclin-dependent kinase 17	0.013
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.013
TNIK	TRAF2 and NCK interacting kinase	0.013
ONECUT1	one cut homeobox 1	0.013
SOX1	SRY (sex determining region Y)-box 1	0.013
CCKBR	cholecystokinin B receptor	0.013	Rat
RAB26	RAB26, member RAS oncogene family	0.013
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.013
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.013
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.013
C1orf93	chromosome 1 open reading frame 93	0.012
CBARA1	calcium binding atopy-related autoantigen 1	0.012
TRPV6	transient receptor potential cation channel, subfamily V, member 6	0.012
AVPR2	arginine vasopressin receptor 2	0.012
SPRR2A	small proline-rich protein 2A	0.012
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.012
GLUD1	glutamate dehydrogenase 1	0.012
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.012
GHR	growth hormone receptor	0.012
FYB	FYN binding protein	0.012
SOCS3	suppressor of cytokine signaling 3	0.012
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.012
EGLN3	egl nine homolog 3 (C. elegans)	0.012
LRP6	low density lipoprotein receptor-related protein 6	0.012
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.012
CSF1R	colony stimulating factor 1 receptor	0.012
CD79B	CD79b molecule, immunoglobulin-associated beta	0.011
OPRD1	opioid receptor, delta 1	0.011	Human
PDCD6IP	programmed cell death 6 interacting protein	0.011
SIX3	SIX homeobox 3	0.011
BBS10	Bardet-Biedl syndrome 10	0.011
TMOD3	tropomodulin 3 (ubiquitous)	0.011
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.011
IGFBP1	insulin-like growth factor binding protein 1	0.011
LHX2	LIM homeobox 2	0.011
HPN	hepsin	0.011
PICALM	phosphatidylinositol binding clathrin assembly protein	0.011
TYROBP	TYRO protein tyrosine kinase binding protein	0.010
FOXO3	forkhead box O3	0.010
MASP2	mannan-binding lectin serine peptidase 2	0.010
PRKCA	protein kinase C, alpha	0.010
AR	androgen receptor	0.010
BCAR1	breast cancer anti-estrogen resistance 1	0.010
MARCKSL1	MARCKS-like 1	0.010
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.010
SH3KBP1	SH3-domain kinase binding protein 1	0.010
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.010