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Homo sapiens

2 genes annotated in human

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cellular defense response

GO:0006968

A defense response that is mediated by cells.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular defense response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular defense response" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
NCF2	neutrophil cytosolic factor 2	0.999
CCL5	chemokine (C-C motif) ligand 5	0.997
NCF4	neutrophil cytosolic factor 4, 40kDa	0.965
C9orf89	chromosome 9 open reading frame 89	0.962
CARD11	caspase recruitment domain family, member 11	0.936
IFNG	interferon, gamma	0.832
CXCR3	chemokine (C-X-C motif) receptor 3	0.758	Human
CCR2	chemokine (C-C motif) receptor 2	0.736	Human Mouse
PRKCD	protein kinase C, delta	0.709
CCL22	chemokine (C-C motif) ligand 22	0.662
CXCR6	chemokine (C-X-C motif) receptor 6	0.646	Human
IL2RB	interleukin 2 receptor, beta	0.633
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.630
PRKCB	protein kinase C, beta	0.618
FASLG	Fas ligand (TNF superfamily, member 6)	0.460
CD40LG	CD40 ligand	0.423
IRF4	interferon regulatory factor 4	0.419
TRIM9	tripartite motif containing 9	0.400
CYBA	cytochrome b-245, alpha polypeptide	0.378
MATK	megakaryocyte-associated tyrosine kinase	0.355
SLAMF7	SLAM family member 7	0.286
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.279
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.252
CCR7	chemokine (C-C motif) receptor 7	0.239	Human
CCL4	chemokine (C-C motif) ligand 4	0.224
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.177
CCR4	chemokine (C-C motif) receptor 4	0.165	Human
CD2	CD2 molecule	0.164
CCR8	chemokine (C-C motif) receptor 8	0.143	Human
CCR6	chemokine (C-C motif) receptor 6	0.137	Human
PDCD6IP	programmed cell death 6 interacting protein	0.131
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.131
CXCL9	chemokine (C-X-C motif) ligand 9	0.129
CXCR5	chemokine (C-X-C motif) receptor 5	0.113	Human
PRKCA	protein kinase C, alpha	0.103
ITK	IL2-inducible T-cell kinase	0.098
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.094
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.090
PRKCQ	protein kinase C, theta	0.089
CCL3	chemokine (C-C motif) ligand 3	0.089
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.081
CXCL13	chemokine (C-X-C motif) ligand 13	0.077
SETD7	SET domain containing (lysine methyltransferase) 7	0.074
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.071
PASK	PAS domain containing serine/threonine kinase	0.071
GPR171	G protein-coupled receptor 171	0.069
SIRT6	sirtuin 6	0.068
CXCR2	chemokine (C-X-C motif) receptor 2	0.063
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.062
CXCR4	chemokine (C-X-C motif) receptor 4	0.059	Human
CFL2	cofilin 2 (muscle)	0.054
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.054
CCL19	chemokine (C-C motif) ligand 19	0.052
FYN	FYN oncogene related to SRC, FGR, YES	0.048
CCL7	chemokine (C-C motif) ligand 7	0.048
GPR18	G protein-coupled receptor 18	0.045
IL1R2	interleukin 1 receptor, type II	0.044
SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	0.044
CCL11	chemokine (C-C motif) ligand 11	0.043
CLEC7A	C-type lectin domain family 7, member A	0.042
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.039
IL21R	interleukin 21 receptor	0.039
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.039
IL1F5	interleukin 1 family, member 5 (delta)	0.038
GZMK	granzyme K (granzyme 3; tryptase II)	0.038
CCR1	chemokine (C-C motif) receptor 1	0.037	Human
LGALS2	lectin, galactoside-binding, soluble, 2	0.036
SIT1	signaling threshold regulating transmembrane adaptor 1	0.035
SLAMF6	SLAM family member 6	0.035
LAG3	lymphocyte-activation gene 3	0.035
PDPK1	3-phosphoinositide dependent protein kinase-1	0.035
CD22	CD22 molecule	0.035
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.033
CLC	Charcot-Leyden crystal protein	0.032
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.031
CD84	CD84 molecule	0.030
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.029
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.029
PRAF2	PRA1 domain family, member 2	0.028
IL10	interleukin 10	0.027
CDCP1	CUB domain containing protein 1	0.026
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.026
IL18RAP	interleukin 18 receptor accessory protein	0.025
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.025
SLC20A1	solute carrier family 20 (phosphate transporter), member 1	0.024
XCR1	chemokine (C motif) receptor 1	0.024	Human
IL2RA	interleukin 2 receptor, alpha	0.023
CXCL11	chemokine (C-X-C motif) ligand 11	0.021
UBASH3A	ubiquitin associated and SH3 domain containing A	0.021
GIMAP4	GTPase, IMAP family member 4	0.021
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.021
PVRIG	poliovirus receptor related immunoglobulin domain containing	0.021
IL2RG	interleukin 2 receptor, gamma	0.020
LY9	lymphocyte antigen 9	0.020
CD226	CD226 molecule	0.020
CD1B	CD1b molecule	0.019
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.019
EOMES	eomesodermin	0.019
CLEC4E	C-type lectin domain family 4, member E	0.019
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.018
IL1A	interleukin 1, alpha	0.018
IL4	interleukin 4	0.018
PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	0.018
DPP4	dipeptidyl-peptidase 4	0.018
RUNX3	runt-related transcription factor 3	0.017
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.017
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.017
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.017
FFAR2	free fatty acid receptor 2	0.016
CCR9	chemokine (C-C motif) receptor 9	0.016	Human
NCR3	natural cytotoxicity triggering receptor 3	0.016
CD1A	CD1a molecule	0.015
PTPRA	protein tyrosine phosphatase, receptor type, A	0.015
CD1C	CD1c molecule	0.015
PDCD1LG2	programmed cell death 1 ligand 2	0.015
BTLA	B and T lymphocyte associated	0.015
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.014
ICOS	inducible T-cell co-stimulator	0.014
TBX21	T-box 21	0.014
IL6R	interleukin 6 receptor	0.014
CD1E	CD1e molecule	0.014
IL5RA	interleukin 5 receptor, alpha	0.014
XCL2	chemokine (C motif) ligand 2	0.014
CD86	CD86 molecule	0.014
ABCD2	ATP-binding cassette, sub-family D (ALD), member 2	0.013
KLRG1	killer cell lectin-like receptor subfamily G, member 1	0.013
TAGAP	T-cell activation RhoGTPase activating protein	0.013
FBXO25	F-box protein 25	0.013
SIRPB1	signal-regulatory protein beta 1	0.013
IL12RB1	interleukin 12 receptor, beta 1	0.013
ZBP1	Z-DNA binding protein 1	0.013
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.013
GZMM	granzyme M (lymphocyte met-ase 1)	0.013
BLK	B lymphoid tyrosine kinase	0.013
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.013
TRAF3IP3	TRAF3 interacting protein 3	0.013
SELL	selectin L	0.012
CD79B	CD79b molecule, immunoglobulin-associated beta	0.012
CD28	CD28 molecule	0.012
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.012
CCL1	chemokine (C-C motif) ligand 1	0.012
TNFRSF25	tumor necrosis factor receptor superfamily, member 25	0.012
TCL1A	T-cell leukemia/lymphoma 1A	0.012
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.012
GPR65	G protein-coupled receptor 65	0.012
IL18R1	interleukin 18 receptor 1	0.012
LAX1	lymphocyte transmembrane adaptor 1	0.012
TLR2	toll-like receptor 2	0.012
TNFRSF18	tumor necrosis factor receptor superfamily, member 18	0.012
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.012
CD101	CD101 molecule	0.012
CCL8	chemokine (C-C motif) ligand 8	0.011
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.011
ZBTB32	zinc finger and BTB domain containing 32	0.011
KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	0.011
PRF1	perforin 1 (pore forming protein)	0.011
FPR2	formyl peptide receptor 2	0.011
TRAT1	T cell receptor associated transmembrane adaptor 1	0.011
CCL23	chemokine (C-C motif) ligand 23	0.011
ACPP	acid phosphatase, prostate	0.011
GRAP2	GRB2-related adaptor protein 2	0.011
NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	0.011
CFL1	cofilin 1 (non-muscle)	0.011
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.011
FAIM3	Fas apoptotic inhibitory molecule 3	0.011
CLEC4D	C-type lectin domain family 4, member D	0.011
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.011
PTPRE	protein tyrosine phosphatase, receptor type, E	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
FCRL2	Fc receptor-like 2	0.011
CXCR1	chemokine (C-X-C motif) receptor 1	0.011	Human
FAM129C	family with sequence similarity 129, member C	0.010
ADAMDEC1	ADAM-like, decysin 1	0.010
IL24	interleukin 24	0.010
RNASE6	ribonuclease, RNase A family, k6	0.010
TIGIT	T cell immunoreceptor with Ig and ITIM domains	0.010
GPR109B	G protein-coupled receptor 109B	0.010
ZBED2	zinc finger, BED-type containing 2	0.010
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.010
RUNX2	runt-related transcription factor 2	0.010
IL17A	interleukin 17A	0.010
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.010