IMP
Process View
positive regulation of membrane protein ectodomain proteolysis
Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of membrane protein ectodomain proteolysis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SNX9 | sorting nexin 9 | 0.999 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.998 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.952 | ||
| SNX33 | sorting nexin 33 | 0.927 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.806 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.775 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.710 | ||
| MPDZ | multiple PDZ domain protein | 0.351 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.335 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.288 | ||
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.242 | Human | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.216 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.199 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.198 | ||
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.189 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.187 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.164 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.157 | ||
| HP | haptoglobin | 0.151 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.140 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.130 | Human | |
| HCK | hemopoietic cell kinase | 0.117 | ||
| FNBP1 | formin binding protein 1 | 0.112 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.079 | ||
| DNM2 | dynamin 2 | 0.072 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.071 | ||
| DNM1 | dynamin 1 | 0.058 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.057 | ||
| A2M | alpha-2-macroglobulin | 0.053 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.045 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.043 | ||
| IL1R2 | interleukin 1 receptor, type II | 0.039 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.039 | ||
| APOC1 | apolipoprotein C-I | 0.036 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.036 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.035 | ||
| APOC3 | apolipoprotein C-III | 0.033 | ||
| TNF | tumor necrosis factor | 0.033 | ||
| ANKRD28 | ankyrin repeat domain 28 | 0.032 | ||
| IL1RAP | interleukin 1 receptor accessory protein | 0.032 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.030 | ||
| IL1B | interleukin 1, beta | 0.029 | ||
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) | 0.028 | ||
| ARRDC3 | arrestin domain containing 3 | 0.027 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.023 | Human | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.022 | ||
| ITK | IL2-inducible T-cell kinase | 0.021 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.020 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.020 | ||
| ADAM12 | ADAM metallopeptidase domain 12 | 0.020 | ||
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.018 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.018 | ||
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.017 | Human | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.016 | ||
| SH3PXD2A | SH3 and PX domains 2A | 0.014 | ||
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.014 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.014 | Human | |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.013 | ||
| SNX18 | sorting nexin 18 | 0.013 | Human | |
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.013 | ||
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.012 | ||
| CD14 | CD14 molecule | 0.012 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.010 | ||
| APP | amyloid beta (A4) precursor protein | 0.010 |