IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

peptidyl proline hydroxylation

GO:0019511

The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "peptidyl proline hydroxylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "peptidyl proline hydroxylation" (in gray)

Name	Description	Probability	Func Analog Organism
Leprel4	leprecan-like 4	0.766
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.745
Prnp	prion protein	0.671
Fkbp9	FK506 binding protein 9	0.532
Epas1	endothelial PAS domain protein 1	0.518
P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	0.452
Txndc5	thioredoxin domain containing 5	0.303
Rpn2	ribophorin II	0.294
Surf4	surfeit gene 4	0.292
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.265
Vegfa	vascular endothelial growth factor A	0.253
Glt25d1	glycosyltransferase 25 domain containing 1	0.239
Lama4	laminin, alpha 4	0.229
Maged1	melanoma antigen, family D, 1	0.227
Sec31a	Sec31 homolog A (S. cerevisiae)	0.220
Creb3l2	cAMP responsive element binding protein 3-like 2	0.214
Ppic	peptidylprolyl isomerase C	0.209
Emilin1	elastin microfibril interfacer 1	0.181
Fkbp10	FK506 binding protein 10	0.168
Copz2	coatomer protein complex, subunit zeta 2	0.168
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.162
Vkorc1	vitamin K epoxide reductase complex, subunit 1	0.158
Rab34	RAB34, member of RAS oncogene family	0.157
Lepre1	leprecan 1	0.156	Mouse
Hsph1	heat shock 105kDa/110kDa protein 1	0.156
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.133
Cul7	cullin 7	0.128
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.117
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.113
Prkcdbp	protein kinase C, delta binding protein	0.104
Nucb1	nucleobindin 1	0.093
Pdia5	protein disulfide isomerase associated 5	0.087
Igfbp4	insulin-like growth factor binding protein 4	0.084
Pcolce	procollagen C-endopeptidase enhancer protein	0.083
Sepn1	selenoprotein N, 1	0.081
Calu	calumenin	0.076
Lamb2	laminin, beta 2	0.074
Egln1	EGL nine homolog 1 (C. elegans)	0.073	Human Rat Worm Fly
Col4a1	collagen, type IV, alpha 1	0.066
Hif1a	hypoxia inducible factor 1, alpha subunit	0.062
Ckap4	cytoskeleton-associated protein 4	0.061
Aldoa	aldolase A, fructose-bisphosphate	0.059
Maged2	melanoma antigen, family D, 2	0.057
Plod2	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2	0.057
Ikbip	IKBKB interacting protein	0.056
Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.052
Gpx7	glutathione peroxidase 7	0.049
Crtap	cartilage associated protein	0.047
Sparc	secreted acidic cysteine rich glycoprotein	0.045
Slc25a28	solute carrier family 25, member 28	0.045
Pfkl	phosphofructokinase, liver, B-type	0.044
Frmd6	FERM domain containing 6	0.039
Anxa5	annexin A5	0.038
Dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.038
Timp3	tissue inhibitor of metalloproteinase 3	0.037
Col4a2	collagen, type IV, alpha 2	0.036
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.036
Fbn1	fibrillin 1	0.036
Dpagt1	dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	0.035
Praf2	PRA1 domain family 2	0.035
Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.035
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.034
Bnip3	BCL2/adenovirus E1B interacting protein 3	0.034
Angptl2	angiopoietin-like 2	0.033
Mxra8	matrix-remodelling associated 8	0.033
Aplp2	amyloid beta (A4) precursor-like protein 2	0.033
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.032
Bhlhe40	basic helix-loop-helix family, member e40	0.032
Itgb5	integrin beta 5	0.031
Hspa5	heat shock protein 5	0.031
Npr2	natriuretic peptide receptor 2	0.031
B3gnt9-ps	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene	0.031
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.030
Sec24d	Sec24 related gene family, member D (S. cerevisiae)	0.028
Dag1	dystroglycan 1	0.028
Smtn	smoothelin	0.028
Lman1	lectin, mannose-binding, 1	0.028
Dctn1	dynactin 1	0.027
Ldha	lactate dehydrogenase A	0.026
Pkm2	pyruvate kinase, muscle	0.025
Bmp1	bone morphogenetic protein 1	0.025
Olfml3	olfactomedin-like 3	0.024
Pgk1	phosphoglycerate kinase 1	0.024
Prkcsh	protein kinase C substrate 80K-H	0.024
Lamc1	laminin, gamma 1	0.024
Atf6	activating transcription factor 6	0.023
Fam114a1	family with sequence similarity 114, member A1	0.023
Vhl	von Hippel-Lindau tumor suppressor	0.023
Gusb	glucuronidase, beta	0.023
Ero1l	ERO1-like (S. cerevisiae)	0.022
Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1	0.022
Cpxm1	carboxypeptidase X 1 (M14 family)	0.022
P4hb	prolyl 4-hydroxylase, beta polypeptide	0.022	Human Worm
Gpr153	G protein-coupled receptor 153	0.021
Morc4	microrchidia 4	0.021
Csrp2	cysteine and glycine-rich protein 2	0.021
Ndn	necdin	0.021
Tmem119	transmembrane protein 119	0.021
Dennd5a	DENN/MADD domain containing 5A	0.019
Lix1l	Lix1-like	0.019
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.019
2700081O15Rik	RIKEN cDNA 2700081O15 gene	0.018
Nek9	NIMA (never in mitosis gene a)-related expressed kinase 9	0.018
Mmp2	matrix metallopeptidase 2	0.018
Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	0.018
Igf2r	insulin-like growth factor 2 receptor	0.017
Nid2	nidogen 2	0.017
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.016
Ankrd40	ankyrin repeat domain 40	0.016
Kdelc2	KDEL (Lys-Asp-Glu-Leu) containing 2	0.016
Bicc1	bicaudal C homolog 1 (Drosophila)	0.016
Sar1a	SAR1 gene homolog A (S. cerevisiae)	0.015
Col5a2	collagen, type V, alpha 2	0.015
Gpr180	G protein-coupled receptor 180	0.015
Col6a3	collagen, type VI, alpha 3	0.015
Ubxn6	UBX domain protein 6	0.015
Gpi1	glucose phosphate isomerase 1	0.014
Hdlbp	high density lipoprotein (HDL) binding protein	0.014
Vegfb	vascular endothelial growth factor B	0.014
Kdelr1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.014
Slc38a10	solute carrier family 38, member 10	0.014
Tpm1	tropomyosin 1, alpha	0.014
Dad1	defender against cell death 1	0.014
Wtip	WT1-interacting protein	0.014
Gga2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	0.014
Gpx8	glutathione peroxidase 8 (putative)	0.014
Bag3	BCL2-associated athanogene 3	0.014
Oaf	OAF homolog (Drosophila)	0.014
Scyl1	SCY1-like 1 (S. cerevisiae)	0.013
Nfil3	nuclear factor, interleukin 3, regulated	0.013
Calhm2	calcium homeostasis modulator 2	0.013
Hk2	hexokinase 2	0.013
Anxa6	annexin A6	0.013
Mlec	malectin	0.012
Trip10	thyroid hormone receptor interactor 10	0.012
C1qtnf6	C1q and tumor necrosis factor related protein 6	0.012
Thbs3	thrombospondin 3	0.012
Tmem45a	transmembrane protein 45a	0.012
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.012
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.012
Pdgfa	platelet derived growth factor, alpha	0.012
Tex261	testis expressed gene 261	0.012
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.012
Osbpl5	oxysterol binding protein-like 5	0.011
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.011
Mfge8	milk fat globule-EGF factor 8 protein	0.011
Smo	smoothened homolog (Drosophila)	0.011
Dnajb2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.011
Slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.011
Dap	death-associated protein	0.011
Rps6ka2	ribosomal protein S6 kinase, polypeptide 2	0.011
Vasn	vasorin	0.011
Ramp2	receptor (calcitonin) activity modifying protein 2	0.011
Gpr124	G protein-coupled receptor 124	0.011
Ostc	oligosaccharyltransferase complex subunit	0.011
Tchhl1	trichohyalin-like 1	0.011
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.011
Tpi1	triosephosphate isomerase 1	0.011
Stbd1	starch binding domain 1	0.010
Plod1	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	0.010
Palld	palladin, cytoskeletal associated protein	0.010
Spns1	spinster homolog 1 (Drosophila)	0.010
Htra1	HtrA serine peptidase 1	0.010
Tpst1	protein-tyrosine sulfotransferase 1	0.010
Emp2	epithelial membrane protein 2	0.010
Lamb1	laminin B1	0.010
Hspa1a	heat shock protein 1A	0.010
Spinkl	serine protease inhibitor, Kazal type-like	0.010
Cd81	CD81 antigen	0.010
Maf1	MAF1 homolog (S. cerevisiae)	0.010
Magee1	melanoma antigen, family E, 1	0.010
Klc1	kinesin light chain 1	0.010