IMP
Process View
negative regulation of platelet derived growth factor receptor signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of platelet derived growth factor receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.994 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.955 | Mouse | |
| Cdh5 | cadherin 5 | 0.738 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.658 | ||
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.558 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.306 | Mouse | |
| Axin1 | axin 1 | 0.246 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.185 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.152 | ||
| She | src homology 2 domain-containing transforming protein E | 0.146 | ||
| Kdr | kinase insert domain protein receptor | 0.141 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.136 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.126 | ||
| Tbx3 | T-box 3 | 0.124 | ||
| Sox17 | SRY-box containing gene 17 | 0.116 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.112 | Mouse | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.101 | Mouse | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.096 | ||
| Ctss | cathepsin S | 0.088 | ||
| Pick1 | protein interacting with C kinase 1 | 0.088 | ||
| Rpe65 | retinal pigment epithelium 65 | 0.087 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.084 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.083 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.083 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.079 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.079 | Mouse | |
| Cldn5 | claudin 5 | 0.079 | ||
| Ly86 | lymphocyte antigen 86 | 0.071 | ||
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.070 | ||
| Ptgir | prostaglandin I receptor (IP) | 0.061 | ||
| Retn | resistin | 0.059 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.057 | ||
| Eng | endoglin | 0.056 | ||
| Rdx | radixin | 0.056 | ||
| Kl | klotho | 0.049 | ||
| Nrxn1 | neurexin I | 0.048 | ||
| Sox18 | SRY-box containing gene 18 | 0.048 | ||
| Ush1c | Usher syndrome 1C homolog (human) | 0.047 | ||
| Stab1 | stabilin 1 | 0.039 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.037 | ||
| Aplnr | apelin receptor | 0.036 | ||
| Tgfa | transforming growth factor alpha | 0.034 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.034 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.033 | ||
| Ifrd1 | interferon-related developmental regulator 1 | 0.032 | ||
| Esam | endothelial cell-specific adhesion molecule | 0.030 | ||
| Plin1 | perilipin 1 | 0.029 | ||
| Robo4 | roundabout homolog 4 (Drosophila) | 0.029 | ||
| Smndc1 | survival motor neuron domain containing 1 | 0.028 | ||
| Npy1r | neuropeptide Y receptor Y1 | 0.028 | ||
| C3ar1 | complement component 3a receptor 1 | 0.028 | ||
| Sox7 | SRY-box containing gene 7 | 0.027 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.027 | ||
| Aif1 | allograft inflammatory factor 1 | 0.027 | ||
| Htra3 | HtrA serine peptidase 3 | 0.027 | ||
| Pld4 | phospholipase D family, member 4 | 0.026 | ||
| BC020535 | cDNA sequence BC020535 | 0.026 | ||
| Rasip1 | Ras interacting protein 1 | 0.026 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.025 | ||
| Tbx2 | T-box 2 | 0.025 | ||
| Pcdh12 | protocadherin 12 | 0.024 | ||
| Kcnj15 | potassium inwardly-rectifying channel, subfamily J, member 15 | 0.024 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.024 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.024 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.023 | ||
| Col4a4 | collagen, type IV, alpha 4 | 0.023 | ||
| Sorbs3 | sorbin and SH3 domain containing 3 | 0.022 | ||
| Sertad2 | SERTA domain containing 2 | 0.022 | ||
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.021 | ||
| Grb7 | growth factor receptor bound protein 7 | 0.021 | ||
| Gpx3 | glutathione peroxidase 3 | 0.021 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.021 | ||
| Egfl7 | EGF-like domain 7 | 0.021 | ||
| Fgd5 | FYVE, RhoGEF and PH domain containing 5 | 0.020 | ||
| Vwf | Von Willebrand factor homolog | 0.020 | ||
| Sox13 | SRY-box containing gene 13 | 0.020 | ||
| Pdzk1 | PDZ domain containing 1 | 0.020 | Mouse | |
| Ptgds | prostaglandin D2 synthase (brain) | 0.019 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.019 | ||
| Crebbp | CREB binding protein | 0.019 | ||
| Zbtb46 | zinc finger and BTB domain containing 46 | 0.019 | ||
| Cfd | complement factor D (adipsin) | 0.018 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.018 | ||
| Wiz | widely-interspaced zinc finger motifs | 0.018 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.017 | ||
| Crtc3 | CREB regulated transcription coactivator 3 | 0.017 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.017 | ||
| Npy2r | neuropeptide Y receptor Y2 | 0.016 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.016 | ||
| Ramp2 | receptor (calcitonin) activity modifying protein 2 | 0.016 | ||
| Fxyd2 | FXYD domain-containing ion transport regulator 2 | 0.016 | ||
| Folr2 | folate receptor 2 (fetal) | 0.016 | ||
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.015 | ||
| Sim1 | single-minded homolog 1 (Drosophila) | 0.015 | ||
| Psen1 | presenilin 1 | 0.015 | ||
| Cftr | cystic fibrosis transmembrane conductance regulator homolog | 0.015 | ||
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.015 | ||
| Card10 | caspase recruitment domain family, member 10 | 0.014 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.014 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.014 | ||
| Gcet2 | germinal center expressed transcript 2 | 0.014 | ||
| Slc6a20b | solute carrier family 6 (neurotransmitter transporter), member 20B | 0.014 | ||
| Myo7a | myosin VIIA | 0.014 | ||
| Mrc1 | mannose receptor, C type 1 | 0.013 | ||
| Nhedc2 | Na+/H+ exchanger domain containing 2 | 0.013 | ||
| Tnxb | tenascin XB | 0.013 | ||
| Mll2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.013 | ||
| Kank3 | KN motif and ankyrin repeat domains 3 | 0.013 | ||
| Corin | corin | 0.013 | ||
| Itgb5 | integrin beta 5 | 0.013 | ||
| Tek | endothelial-specific receptor tyrosine kinase | 0.012 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.012 | ||
| Kcna4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.012 | ||
| Mpeg1 | macrophage expressed gene 1 | 0.012 | ||
| Adora2a | adenosine A2a receptor | 0.012 | ||
| Adcy4 | adenylate cyclase 4 | 0.012 | ||
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.012 | ||
| Lrfn1 | leucine rich repeat and fibronectin type III domain containing 1 | 0.012 | ||
| Gata2 | GATA binding protein 2 | 0.012 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.011 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.011 | ||
| Aff2 | AF4/FMR2 family, member 2 | 0.011 | ||
| Mogat2 | monoacylglycerol O-acyltransferase 2 | 0.011 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.011 | ||
| Hoxb6 | homeobox B6 | 0.011 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.011 | ||
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.011 | ||
| P2ry6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 0.011 | ||
| Tmem176b | transmembrane protein 176B | 0.011 | ||
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.011 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.011 | ||
| Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.011 | ||
| AU021092 | expressed sequence AU021092 | 0.011 | ||
| 4933407C03Rik | RIKEN cDNA 4933407C03 gene | 0.011 | ||
| Smad7 | MAD homolog 7 (Drosophila) | 0.011 | ||
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.011 | ||
| Rem1 | rad and gem related GTP binding protein 1 | 0.011 | ||
| Ltc4s | leukotriene C4 synthase | 0.011 | ||
| Rapgef3 | Rap guanine nucleotide exchange factor (GEF) 3 | 0.010 | ||
| Bspry | B-box and SPRY domain containing | 0.010 | ||
| Fn1 | fibronectin 1 | 0.010 | ||
| Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D | 0.010 | ||
| Timp4 | tissue inhibitor of metalloproteinase 4 | 0.010 | ||
| Gja4 | gap junction protein, alpha 4 | 0.010 | ||
| Sntg2 | syntrophin, gamma 2 | 0.010 | ||
| Fcgr3 | Fc receptor, IgG, low affinity III | 0.010 | ||
| Kap | kidney androgen regulated protein | 0.010 | ||
| Pdzd3 | PDZ domain containing 3 | 0.010 | Mouse |