IMP
Process View
negative regulation of platelet derived growth factor receptor beta signaling pathway
Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of platelet derived growth factor receptor beta signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.810 | ||
| Axin1 | axin 1 | 0.755 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.721 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.494 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.460 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.449 | Mouse | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.446 | ||
| Apoe | apolipoprotein E | 0.423 | ||
| Tbx3 | T-box 3 | 0.413 | ||
| Apc | adenomatosis polyposis coli | 0.365 | ||
| Npc1 | Niemann Pick type C1 | 0.350 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.340 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.275 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.248 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.235 | ||
| Sertad2 | SERTA domain containing 2 | 0.225 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.203 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.196 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.137 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.135 | ||
| Crtc3 | CREB regulated transcription coactivator 3 | 0.106 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.097 | ||
| App | amyloid beta (A4) precursor protein | 0.086 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.079 | ||
| Mesdc2 | mesoderm development candidate 2 | 0.075 | ||
| Smo | smoothened homolog (Drosophila) | 0.066 | ||
| Psen1 | presenilin 1 | 0.065 | ||
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.063 | ||
| Ldlr | low density lipoprotein receptor | 0.057 | ||
| Pick1 | protein interacting with C kinase 1 | 0.057 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.049 | ||
| Glg1 | golgi apparatus protein 1 | 0.049 | ||
| Lepr | leptin receptor | 0.047 | ||
| Bmp1 | bone morphogenetic protein 1 | 0.046 | ||
| Plin1 | perilipin 1 | 0.042 | ||
| Fn1 | fibronectin 1 | 0.041 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.040 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.040 | ||
| Lrp4 | low density lipoprotein receptor-related protein 4 | 0.037 | Mouse | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.037 | ||
| Il6st | interleukin 6 signal transducer | 0.036 | ||
| Cav1 | caveolin 1, caveolae protein | 0.036 | ||
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.035 | Mouse | |
| Il1r1 | interleukin 1 receptor, type I | 0.034 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.033 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.033 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.032 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.032 | ||
| Itgb5 | integrin beta 5 | 0.031 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.031 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.031 | ||
| Ptms | parathymosin | 0.029 | ||
| Gpx3 | glutathione peroxidase 3 | 0.028 | ||
| Runx2 | runt related transcription factor 2 | 0.028 | ||
| Maged1 | melanoma antigen, family D, 1 | 0.027 | ||
| Lpin1 | lipin 1 | 0.027 | ||
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.026 | ||
| Wls | wntless homolog (Drosophila) | 0.025 | ||
| Ptprf | protein tyrosine phosphatase, receptor type, F | 0.025 | ||
| Sox11 | SRY-box containing gene 11 | 0.025 | ||
| Pofut1 | protein O-fucosyltransferase 1 | 0.025 | ||
| Numb | numb gene homolog (Drosophila) | 0.024 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.023 | ||
| Sntg2 | syntrophin, gamma 2 | 0.023 | ||
| T | brachyury | 0.023 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.022 | ||
| Igf1r | insulin-like growth factor I receptor | 0.022 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.022 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.022 | ||
| Jak1 | Janus kinase 1 | 0.021 | ||
| Gtf2ird1 | general transcription factor II I repeat domain-containing 1 | 0.021 | ||
| Tcf7l1 | transcription factor 7-like 1 (T-cell specific, HMG box) | 0.021 | ||
| Msx2 | homeobox, msh-like 2 | 0.020 | ||
| Pltp | phospholipid transfer protein | 0.020 | ||
| Igfbp4 | insulin-like growth factor binding protein 4 | 0.020 | ||
| Ltbr | lymphotoxin B receptor | 0.020 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.020 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.019 | ||
| H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 0.019 | ||
| Mks1 | Meckel syndrome, type 1 | 0.019 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.019 | ||
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.018 | ||
| Brd4 | bromodomain containing 4 | 0.018 | ||
| Anpep | alanyl (membrane) aminopeptidase | 0.018 | ||
| Ifrd1 | interferon-related developmental regulator 1 | 0.018 | ||
| Tax1bp3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.017 | ||
| Crebbp | CREB binding protein | 0.017 | ||
| Umod | uromodulin | 0.017 | ||
| Bmper | BMP-binding endothelial regulator | 0.017 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.017 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.016 | ||
| Arpc2 | actin related protein 2/3 complex, subunit 2 | 0.016 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.016 | ||
| Wwc2 | WW, C2 and coiled-coil domain containing 2 | 0.016 | ||
| Scaf4 | SR-related CTD-associated factor 4 | 0.016 | ||
| C3 | complement component 3 | 0.016 | ||
| Ski | ski sarcoma viral oncogene homolog (avian) | 0.015 | ||
| Irf6 | interferon regulatory factor 6 | 0.015 | ||
| Meox2 | mesenchyme homeobox 2 | 0.015 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.014 | ||
| Nab2 | Ngfi-A binding protein 2 | 0.014 | ||
| Igf1 | insulin-like growth factor 1 | 0.014 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.014 | ||
| Dab2 | disabled homolog 2 (Drosophila) | 0.014 | ||
| Cbfb | core binding factor beta | 0.014 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.014 | ||
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.014 | ||
| Ift88 | intraflagellar transport 88 homolog (Chlamydomonas) | 0.014 | ||
| Amotl2 | angiomotin-like 2 | 0.013 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.013 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.013 | ||
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.013 | ||
| Htt | huntingtin | 0.013 | ||
| Ncor2 | nuclear receptor co-repressor 2 | 0.013 | ||
| Gas1 | growth arrest specific 1 | 0.013 | ||
| Clstn1 | calsyntenin 1 | 0.013 | ||
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.012 | ||
| Smagp | small cell adhesion glycoprotein | 0.012 | ||
| Grn | granulin | 0.012 | ||
| Npy1r | neuropeptide Y receptor Y1 | 0.012 | ||
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.012 | ||
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.012 | ||
| 4933407C03Rik | RIKEN cDNA 4933407C03 gene | 0.012 | ||
| Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.012 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.012 | ||
| Esf1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.012 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.012 | ||
| Pvrl2 | poliovirus receptor-related 2 | 0.012 | ||
| Ext1 | exostoses (multiple) 1 | 0.012 | ||
| Lima1 | LIM domain and actin binding 1 | 0.012 | ||
| Pros1 | protein S (alpha) | 0.011 | ||
| Marcksl1 | MARCKS-like 1 | 0.011 | ||
| Stab1 | stabilin 1 | 0.011 | ||
| Kctd10 | potassium channel tetramerisation domain containing 10 | 0.011 | ||
| Eif1a | eukaryotic translation initiation factor 1A | 0.011 | ||
| Spp1 | secreted phosphoprotein 1 | 0.011 | ||
| Arrb1 | arrestin, beta 1 | 0.011 | ||
| Ets2 | E26 avian leukemia oncogene 2, 3' domain | 0.011 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.011 | ||
| Flii | flightless I homolog (Drosophila) | 0.011 | ||
| Zfhx3 | zinc finger homeobox 3 | 0.011 | ||
| Tshz1 | teashirt zinc finger family member 1 | 0.011 | ||
| Tab1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.011 | ||
| Mn1 | meningioma 1 | 0.011 | ||
| Rest | RE1-silencing transcription factor | 0.011 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.011 | ||
| Itga3 | integrin alpha 3 | 0.011 | ||
| Med10 | mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae) | 0.010 | ||
| Grb7 | growth factor receptor bound protein 7 | 0.010 | ||
| Npr2 | natriuretic peptide receptor 2 | 0.010 | ||
| Col4a2 | collagen, type IV, alpha 2 | 0.010 | ||
| Sox13 | SRY-box containing gene 13 | 0.010 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.010 | ||
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.010 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.010 |