IMP
Process View
regulation of release of cytochrome c from mitochondria
Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "regulation of release of cytochrome c from mitochondria"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.998 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.973 | Human | |
| Bax | BCL2-associated X protein | 0.690 | Human | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.541 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.487 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.375 | ||
| Pten | phosphatase and tensin homolog | 0.374 | ||
| Mcl1 | myeloid cell leukemia sequence 1 | 0.300 | ||
| Lepr | leptin receptor | 0.288 | ||
| Igf1r | insulin-like growth factor I receptor | 0.279 | ||
| Gbp5 | guanylate binding protein 5 | 0.245 | ||
| Grb10 | growth factor receptor bound protein 10 | 0.244 | ||
| Aim2 | absent in melanoma 2 | 0.235 | ||
| Ldb3 | LIM domain binding 3 | 0.211 | ||
| Casp1 | caspase 1 | 0.186 | ||
| Insr | insulin receptor | 0.184 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.183 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.120 | ||
| Igh | immunoglobulin heavy chain complex | 0.104 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.103 | ||
| Smn1 | survival motor neuron 1 | 0.098 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.098 | ||
| Rxra | retinoid X receptor alpha | 0.083 | ||
| Stim2 | stromal interaction molecule 2 | 0.072 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.069 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.069 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.068 | ||
| Becn1 | beclin 1, autophagy related | 0.067 | ||
| Cd28 | CD28 antigen | 0.067 | ||
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.065 | ||
| Traf3ip2 | TRAF3 interacting protein 2 | 0.063 | ||
| Kit | kit oncogene | 0.061 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.058 | ||
| Ghr | growth hormone receptor | 0.056 | ||
| Opa1 | optic atrophy 1 homolog (human) | 0.056 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.054 | ||
| Egfr | epidermal growth factor receptor | 0.053 | ||
| Casp3 | caspase 3 | 0.051 | ||
| Mfn2 | mitofusin 2 | 0.048 | ||
| Igf2r | insulin-like growth factor 2 receptor | 0.048 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.047 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.047 | ||
| Lyst | lysosomal trafficking regulator | 0.046 | ||
| Cdkn1c | cyclin-dependent kinase inhibitor 1C (P57) | 0.045 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.044 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.042 | ||
| Bcl2l1 | BCL2-like 1 | 0.039 | Human | |
| Bbc3 | BCL2 binding component 3 | 0.038 | ||
| Mtor | mechanistic target of rapamycin (serine/threonine kinase) | 0.038 | ||
| Nphs2 | nephrosis 2 homolog, podocin (human) | 0.037 | ||
| Cd151 | CD151 antigen | 0.035 | ||
| Commd6 | COMM domain containing 6 | 0.034 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.032 | ||
| Ccdc58 | coiled-coil domain containing 58 | 0.032 | ||
| Trp53 | transformation related protein 53 | 0.031 | Human | |
| Col4a3 | collagen, type IV, alpha 3 | 0.031 | ||
| Triap1 | TP53 regulated inhibitor of apoptosis 1 | 0.030 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.030 | ||
| Tmem223 | transmembrane protein 223 | 0.029 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.029 | ||
| Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.028 | ||
| Mmp2 | matrix metallopeptidase 2 | 0.027 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.027 | ||
| Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.027 | ||
| Psma4 | proteasome (prosome, macropain) subunit, alpha type 4 | 0.025 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.025 | ||
| Sncaip | synuclein, alpha interacting protein (synphilin) | 0.024 | ||
| Tpi1 | triosephosphate isomerase 1 | 0.023 | ||
| Apoe | apolipoprotein E | 0.023 | ||
| Pomp | proteasome maturation protein | 0.022 | ||
| Ins2 | insulin II | 0.020 | Mouse | |
| Ifrd2 | interferon-related developmental regulator 2 | 0.020 | ||
| Plcb1 | phospholipase C, beta 1 | 0.020 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.019 | ||
| Tyro3 | TYRO3 protein tyrosine kinase 3 | 0.018 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.018 | ||
| Wrn | Werner syndrome homolog (human) | 0.018 | ||
| Blnk | B-cell linker | 0.018 | ||
| Axl | AXL receptor tyrosine kinase | 0.018 | ||
| Prkce | protein kinase C, epsilon | 0.017 | ||
| Nubp1 | nucleotide binding protein 1 | 0.016 | ||
| Gphn | gephyrin | 0.016 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.016 | ||
| Pxn | paxillin | 0.016 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.015 | ||
| E2f1 | E2F transcription factor 1 | 0.015 | ||
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.015 | ||
| Actn2 | actinin alpha 2 | 0.015 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.015 | ||
| Thrb | thyroid hormone receptor beta | 0.014 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.014 | ||
| Nampt | nicotinamide phosphoribosyltransferase | 0.014 | ||
| Slc30a9 | solute carrier family 30 (zinc transporter), member 9 | 0.014 | ||
| Marveld2 | MARVEL (membrane-associating) domain containing 2 | 0.014 | ||
| Foxo1 | forkhead box O1 | 0.014 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.014 | ||
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.014 | ||
| Emg1 | EMG1 nucleolar protein homolog (S. cerevisiae) | 0.014 | ||
| Atp6v1f | ATPase, H+ transporting, lysosomal V1 subunit F | 0.014 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.013 | ||
| Wwox | WW domain-containing oxidoreductase | 0.013 | ||
| Mrps2 | mitochondrial ribosomal protein S2 | 0.013 | ||
| Foxp3 | forkhead box P3 | 0.013 | ||
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.013 | ||
| Pthlh | parathyroid hormone-like peptide | 0.013 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.013 | ||
| Vegfa | vascular endothelial growth factor A | 0.013 | ||
| Irs2 | insulin receptor substrate 2 | 0.013 | ||
| Tomm40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 0.012 | ||
| Cav1 | caveolin 1, caveolae protein | 0.012 | ||
| Itga1 | integrin alpha 1 | 0.012 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.012 | ||
| Cd79b | CD79B antigen | 0.012 | ||
| Coq7 | demethyl-Q 7 | 0.012 | ||
| 0610011F06Rik | RIKEN cDNA 0610011F06 gene | 0.012 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.012 | ||
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.012 | ||
| Ltk | leukocyte tyrosine kinase | 0.011 | ||
| Rab24 | RAB24, member RAS oncogene family | 0.011 | ||
| Per3 | period homolog 3 (Drosophila) | 0.011 | ||
| Timp1 | tissue inhibitor of metalloproteinase 1 | 0.011 | ||
| Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | 0.011 | ||
| Cenpb | centromere protein B | 0.011 | ||
| Cd40 | CD40 antigen | 0.011 | ||
| Ubl5 | ubiquitin-like 5 | 0.011 | ||
| Supv3l1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.011 | ||
| Ccnd1 | cyclin D1 | 0.010 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.010 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.010 |