IMP

Process View

Mus musculus

13 genes annotated in mouse

bone maturation

A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.

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In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "bone maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bone maturation" (in gray)

Name	Description	Probability	Func Analog Organism
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.797	Mouse
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.709
Fgfr3	fibroblast growth factor receptor 3	0.548
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.395
Fgfr2	fibroblast growth factor receptor 2	0.345	Mouse
Ednra	endothelin receptor type A	0.326
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.239
Smad3	MAD homolog 3 (Drosophila)	0.236
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.187
Nrp1	neuropilin 1	0.162
Shh	sonic hedgehog	0.108
Sox9	SRY-box containing gene 9	0.101
Ptch1	patched homolog 1	0.076
Fgfr1	fibroblast growth factor receptor 1	0.075	Mouse
Gja1	gap junction protein, alpha 1	0.067
Prrx1	paired related homeobox 1	0.066
Vdr	vitamin D receptor	0.060
Plxna4	plexin A4	0.054	Mouse
Pthlh	parathyroid hormone-like peptide	0.053
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.049
Thbs1	thrombospondin 1	0.049	Mouse
Scn5a	sodium channel, voltage-gated, type V, alpha	0.048
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.048
Nf1	neurofibromatosis 1	0.047
Ltbp1	latent transforming growth factor beta binding protein 1	0.043
Gli3	GLI-Kruppel family member GLI3	0.037
Dll1	delta-like 1 (Drosophila)	0.035
Pbx1	pre B-cell leukemia transcription factor 1	0.035
Tgfb2	transforming growth factor, beta 2	0.033
Fbn1	fibrillin 1	0.031
Epha4	Eph receptor A4	0.029
Rgnef	Rho-guanine nucleotide exchange factor	0.029
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.027
Bmp7	bone morphogenetic protein 7	0.027
Sdc3	syndecan 3	0.027
Ednrb	endothelin receptor type B	0.026
Casq2	calsequestrin 2	0.026
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.025
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.025
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.024
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.023
Nos3	nitric oxide synthase 3, endothelial cell	0.023
Acvr1	activin A receptor, type 1	0.021
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.021	Mouse
Gli2	GLI-Kruppel family member GLI2	0.020
Foxc1	forkhead box C1	0.019
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.018
Meox2	mesenchyme homeobox 2	0.018
Pax3	paired box gene 3	0.018
Trp53	transformation related protein 53	0.017
Wdr1	WD repeat domain 1	0.017
Thbs2	thrombospondin 2	0.017	Mouse
Smo	smoothened homolog (Drosophila)	0.017
Col1a1	collagen, type I, alpha 1	0.017
Pkdcc	protein kinase domain containing, cytoplasmic	0.016
Rara	retinoic acid receptor, alpha	0.016
Timp1	tissue inhibitor of metalloproteinase 1	0.016
Plxna1	plexin A1	0.015	Mouse
Lepr	leptin receptor	0.015
Fgfrl1	fibroblast growth factor receptor-like 1	0.015
Efnb2	ephrin B2	0.015
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.015
Phldb1	pleckstrin homology-like domain, family B, member 1	0.015
Nrp2	neuropilin 2	0.015
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.014
Mmp15	matrix metallopeptidase 15	0.014
Col8a1	collagen, type VIII, alpha 1	0.014
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.013
Idua	iduronidase, alpha-L-	0.013
Wwtr1	WW domain containing transcription regulator 1	0.013
Grb10	growth factor receptor bound protein 10	0.012
Ctsk	cathepsin K	0.012
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.012
Klf6	Kruppel-like factor 6	0.012
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.012
Tgfbr2	transforming growth factor, beta receptor II	0.012
Mrc2	mannose receptor, C type 2	0.012
Matn4	matrilin 4	0.012
Cxadr	coxsackie virus and adenovirus receptor	0.012
Fzd1	frizzled homolog 1 (Drosophila)	0.012
Ltbp3	latent transforming growth factor beta binding protein 3	0.012
Msn	moesin	0.012
Rac1	RAS-related C3 botulinum substrate 1	0.012
Unc5b	unc-5 homolog B (C. elegans)	0.012
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.012
Ctgf	connective tissue growth factor	0.012
Rarg	retinoic acid receptor, gamma	0.012
Axl	AXL receptor tyrosine kinase	0.011
Ephb3	Eph receptor B3	0.011
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.011
Col5a1	collagen, type V, alpha 1	0.011
Myadm	myeloid-associated differentiation marker	0.011
Fbn2	fibrillin 2	0.011
Tbx5	T-box 5	0.011
Csf1	colony stimulating factor 1 (macrophage)	0.011
Mcam	melanoma cell adhesion molecule	0.011
Tnni1	troponin I, skeletal, slow 1	0.011
Bmp1	bone morphogenetic protein 1	0.010
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.010
Ikbkb	inhibitor of kappaB kinase beta	0.010