IMP

Process View

Mus musculus

10 genes annotated in mouse

Multi-species View

positive regulation of mast cell degranulation

GO:0043306

Any process that activates or increases the frequency, rate or extent of mast cell degranulation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mast cell degranulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of mast cell degranulation" (in gray)

Name	Description	Probability	Func Analog Organism
Inpp5d	inositol polyphosphate-5-phosphatase D	0.984
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.890	Mouse
Grb2	growth factor receptor bound protein 2	0.884
Ptprc	protein tyrosine phosphatase, receptor type, C	0.864
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.680	Mouse
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.641
Mefv	Mediterranean fever	0.468
Ikzf1	IKAROS family zinc finger 1	0.446
Cbl	Casitas B-lineage lymphoma	0.422
Tyrobp	TYRO protein tyrosine kinase binding protein	0.357
Dok1	docking protein 1	0.357
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.344
Fas	Fas (TNF receptor superfamily member 6)	0.259
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.222
Stat6	signal transducer and activator of transcription 6	0.212
C3ar1	complement component 3a receptor 1	0.205
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.188
Lat	linker for activation of T cells	0.177
Shc1	src homology 2 domain-containing transforming protein C1	0.119
Cd247	CD247 antigen	0.115	Mouse
Msr1	macrophage scavenger receptor 1	0.106
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.101
Ptk2	PTK2 protein tyrosine kinase 2	0.100
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.099
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.093	Mouse
Met	met proto-oncogene	0.084
Il4	interleukin 4	0.082
Il2rb	interleukin 2 receptor, beta chain	0.079
Was	Wiskott-Aldrich syndrome homolog (human)	0.077
Hcst	hematopoietic cell signal transducer	0.074
Dok2	docking protein 2	0.071
Cd40	CD40 antigen	0.071
Dok3	docking protein 3	0.070
Lair1	leukocyte-associated Ig-like receptor 1	0.070
Nfam1	Nfat activating molecule with ITAM motif 1	0.068
Clec4n	C-type lectin domain family 4, member n	0.060
Tbxas1	thromboxane A synthase 1, platelet	0.057
Rag1	recombination activating gene 1	0.055
Kit	kit oncogene	0.054
C5ar1	complement component 5a receptor 1	0.053
Ccr6	chemokine (C-C motif) receptor 6	0.051
Csf1r	colony stimulating factor 1 receptor	0.046
Fasl	Fas ligand (TNF superfamily, member 6)	0.045
Il2rg	interleukin 2 receptor, gamma chain	0.044
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.044
Il4ra	interleukin 4 receptor, alpha	0.043
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.043
Hck	hemopoietic cell kinase	0.042	Mouse
Fpr2	formyl peptide receptor 2	0.039
Irg1	immunoresponsive gene 1	0.038
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.038
Fcgr1	Fc receptor, IgG, high affinity I	0.038	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.035
Cd180	CD180 antigen	0.035
Plek	pleckstrin	0.034
Clec4d	C-type lectin domain family 4, member d	0.032
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.032
Il10ra	interleukin 10 receptor, alpha	0.032
Prkce	protein kinase C, epsilon	0.032
Fcgr3	Fc receptor, IgG, low affinity III	0.031	Mouse
Trem3	triggering receptor expressed on myeloid cells 3	0.030
Itk	IL2-inducible T-cell kinase	0.030
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.030
Ifng	interferon gamma	0.029
Fcgr4	Fc receptor, IgG, low affinity IV	0.029
Plcg2	phospholipase C, gamma 2	0.028
Tcra	T-cell receptor alpha chain	0.028
AF251705	cDNA sequence AF251705	0.027	Mouse
Cd4	CD4 antigen	0.024
Ptpre	protein tyrosine phosphatase, receptor type, E	0.023
Ncf1	neutrophil cytosolic factor 1	0.023
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.022
Slc15a3	solute carrier family 15, member 3	0.022
Hmox1	heme oxygenase (decycling) 1	0.022
Zap70	zeta-chain (TCR) associated protein kinase	0.021	Mouse
Mpeg1	macrophage expressed gene 1	0.021
Grap2	GRB2-related adaptor protein 2	0.020
Fes	feline sarcoma oncogene	0.019
Il2	interleukin 2	0.019
Il18rap	interleukin 18 receptor accessory protein	0.019
Cd8a	CD8 antigen, alpha chain	0.019
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.019	Mouse
Plcg1	phospholipase C, gamma 1	0.019
Itgb3	integrin beta 3	0.018
Ccr1	chemokine (C-C motif) receptor 1	0.018
Pou2f2	POU domain, class 2, transcription factor 2	0.018
Ncr1	natural cytotoxicity triggering receptor 1	0.018
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.018
Sykb	spleen tyrosine kinase	0.018
Cd28	CD28 antigen	0.018
Gab2	growth factor receptor bound protein 2-associated protein 2	0.018
Hk3	hexokinase 3	0.017
Rgs14	regulator of G-protein signaling 14	0.017
Igsf6	immunoglobulin superfamily, member 6	0.017
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.017
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.017
Fpr1	formyl peptide receptor 1	0.016
Ptpra	protein tyrosine phosphatase, receptor type, A	0.016
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.016
Rasgrp1	RAS guanyl releasing protein 1	0.016
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.016
BC013712	cDNA sequence BC013712	0.016
Mmp8	matrix metallopeptidase 8	0.016
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.015
Cd300a	CD300A antigen	0.015	Mouse
Itgax	integrin alpha X	0.015
Cd86	CD86 antigen	0.015
Pxn	paxillin	0.015
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.015
Mb	myoglobin	0.015
Fyn	Fyn proto-oncogene	0.015	Mouse
Cxcr2	chemokine (C-X-C motif) receptor 2	0.014
Cd6	CD6 antigen	0.014
Lck	lymphocyte protein tyrosine kinase	0.014	Mouse
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.014
Marco	macrophage receptor with collagenous structure	0.013
Cd300ld	CD300 molecule-like family member d	0.013
Vav1	vav 1 oncogene	0.013
Cd22	CD22 antigen	0.013
Siglece	sialic acid binding Ig-like lectin E	0.013
F7	coagulation factor VII	0.013
Cd96	CD96 antigen	0.013
Sfpi1	SFFV proviral integration 1	0.012
Clec7a	C-type lectin domain family 7, member a	0.012
Ccl17	chemokine (C-C motif) ligand 17	0.012
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.012
Pou2af1	POU domain, class 2, associating factor 1	0.012
Aoah	acyloxyacyl hydrolase	0.012
Slfn4	schlafen 4	0.012
Adam8	a disintegrin and metallopeptidase domain 8	0.012
Slfn2	schlafen 2	0.012
Fyb	FYN binding protein	0.012
Cmklr1	chemokine-like receptor 1	0.012
Sla2	Src-like-adaptor 2	0.012
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
Il1rn	interleukin 1 receptor antagonist	0.011
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.011
Gpr132	G protein-coupled receptor 132	0.011
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.011
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
Tmem106a	transmembrane protein 106A	0.011
Cd7	CD7 antigen	0.011
Il1r2	interleukin 1 receptor, type II	0.010
Trem1	triggering receptor expressed on myeloid cells 1	0.010
Icos	inducible T-cell co-stimulator	0.010
Bst1	bone marrow stromal cell antigen 1	0.010