IMP
Process View
negative regulation of g1 s transition of mitotic cell cycle
Any cell cycle regulatory process that prevents the commitment of a cell from G1 to S phase of the mitotic cell cycle.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of g1 s transition of mitotic cell cycle"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 0.999 | ||
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.911 | Fly | |
| Rb1 | retinoblastoma 1 | 0.897 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.645 | ||
| Pten | phosphatase and tensin homolog | 0.613 | Human | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.359 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.301 | ||
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.241 | Fly | |
| Apc | adenomatosis polyposis coli | 0.220 | ||
| Nf1 | neurofibromatosis 1 | 0.200 | ||
| Brca1 | breast cancer 1 | 0.200 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.184 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.176 | ||
| E2f1 | E2F transcription factor 1 | 0.159 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.154 | ||
| Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.148 | Fly | |
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.141 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.133 | ||
| Kit | kit oncogene | 0.107 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.101 | ||
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.090 | Fly | |
| Cd80 | CD80 antigen | 0.090 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.076 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.068 | ||
| Ret | ret proto-oncogene | 0.062 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.057 | ||
| Aebp2 | AE binding protein 2 | 0.056 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.056 | ||
| Nbn | nibrin | 0.054 | ||
| Ptch1 | patched homolog 1 | 0.052 | ||
| Rbl2 | retinoblastoma-like 2 | 0.050 | Mouse Fly | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.044 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.043 | Mouse Fly | |
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.042 | ||
| Stk11 | serine/threonine kinase 11 | 0.039 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.037 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.036 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.033 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.033 | ||
| Braf | Braf transforming gene | 0.032 | ||
| Foxo3 | forkhead box O3 | 0.032 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.030 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.029 | Human | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.028 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.028 | ||
| Cdkn2d | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 0.027 | ||
| Bax | BCL2-associated X protein | 0.027 | Mouse | |
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.025 | Fly | |
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.025 | ||
| Brca2 | breast cancer 2 | 0.024 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.022 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.022 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.022 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.022 | ||
| Ptpn13 | protein tyrosine phosphatase, non-receptor type 13 | 0.022 | ||
| Shh | sonic hedgehog | 0.021 | ||
| Meox2 | mesenchyme homeobox 2 | 0.020 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.020 | Human | |
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.019 | ||
| Tcf3 | transcription factor 3 | 0.019 | ||
| Runx1 | runt related transcription factor 1 | 0.019 | ||
| Nrg1 | neuregulin 1 | 0.018 | ||
| Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.018 | ||
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.017 | ||
| Stk38 | serine/threonine kinase 38 | 0.017 | ||
| Gja1 | gap junction protein, alpha 1 | 0.017 | ||
| A930001N09Rik | RIKEN cDNA A930001N09 gene | 0.017 | ||
| Zfp830 | zinc finger protein 830 | 0.016 | ||
| Tfdp2 | transcription factor Dp 2 | 0.016 | ||
| Lrrc58 | leucine rich repeat containing 58 | 0.016 | ||
| Skil | SKI-like | 0.016 | ||
| Tsc1 | tuberous sclerosis 1 | 0.015 | ||
| Rara | retinoic acid receptor, alpha | 0.015 | ||
| Pdcd1 | programmed cell death 1 | 0.015 | ||
| Daxx | Fas death domain-associated protein | 0.015 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.015 | ||
| Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.015 | ||
| Osbpl11 | oxysterol binding protein-like 11 | 0.015 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.015 | ||
| Hdac1 | histone deacetylase 1 | 0.014 | ||
| Nf2 | neurofibromatosis 2 | 0.014 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.014 | ||
| Cdk6 | cyclin-dependent kinase 6 | 0.014 | ||
| Numa1 | nuclear mitotic apparatus protein 1 | 0.014 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.014 | Mouse | |
| Rxra | retinoid X receptor alpha | 0.014 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.013 | Mouse | |
| Psen1 | presenilin 1 | 0.013 | ||
| Kif16b | kinesin family member 16B | 0.012 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.012 | ||
| Cbl | Casitas B-lineage lymphoma | 0.012 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.012 | ||
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.012 | ||
| Ulk2 | Unc-51 like kinase 2 (C. elegans) | 0.012 | ||
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.012 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.011 | ||
| Ntf3 | neurotrophin 3 | 0.011 | ||
| Hdac2 | histone deacetylase 2 | 0.011 | ||
| Ccdc117 | coiled-coil domain containing 117 | 0.011 | ||
| Pcna | proliferating cell nuclear antigen | 0.011 | ||
| Ubr3 | ubiquitin protein ligase E3 component n-recognin 3 | 0.011 | ||
| Cenpf | centromere protein F | 0.011 | ||
| Nek8 | NIMA (never in mitosis gene a)-related expressed kinase 8 | 0.011 | ||
| Smn1 | survival motor neuron 1 | 0.011 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A2 | 0.011 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.011 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.010 | ||
| Thbs1 | thrombospondin 1 | 0.010 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.010 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.010 | ||
| Mtf2 | metal response element binding transcription factor 2 | 0.010 |