IMP

Process View

Mus musculus

18 genes annotated in mouse

neutral lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neutral lipid biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neutral lipid biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Apoe	apolipoprotein E	0.955
Pparg	peroxisome proliferator activated receptor gamma	0.855
Dab1	disabled homolog 1 (Drosophila)	0.807
Pnpla2	patatin-like phospholipase domain containing 2	0.746
Cav1	caveolin 1, caveolae protein	0.730
Scd1	stearoyl-Coenzyme A desaturase 1	0.541
Ghr	growth hormone receptor	0.506
Abhd5	abhydrolase domain containing 5	0.297
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.271
Dhcr7	7-dehydrocholesterol reductase	0.197
Cidec	cell death-inducing DFFA-like effector c	0.172
Lpin1	lipin 1	0.156
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.154
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.149
Srf	serum response factor	0.147
Lep	leptin	0.143
Sqle	squalene epoxidase	0.128
Irs2	insulin receptor substrate 2	0.120
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.120
Dhcr24	24-dehydrocholesterol reductase	0.115
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.114
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.114
Apoc1	apolipoprotein C-I	0.111
Flt1	FMS-like tyrosine kinase 1	0.096
Fabp4	fatty acid binding protein 4, adipocyte	0.085
Lpl	lipoprotein lipase	0.081
Adipoq	adiponectin, C1Q and collagen domain containing	0.072
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.066
Fasn	fatty acid synthase	0.066
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.065
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.062
Lipe	lipase, hormone sensitive	0.056
Cyp51	cytochrome P450, family 51	0.054
Nos3	nitric oxide synthase 3, endothelial cell	0.054
Gjb2	gap junction protein, beta 2	0.054
Lrp5	low density lipoprotein receptor-related protein 5	0.051
Psen1	presenilin 1	0.050
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.050
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.049
Notch2	Notch gene homolog 2 (Drosophila)	0.049
Pcx	pyruvate carboxylase	0.047
Lcat	lecithin cholesterol acyltransferase	0.047
Adipor2	adiponectin receptor 2	0.046
Vldlr	very low density lipoprotein receptor	0.044	Mouse
Npc1	Niemann Pick type C1	0.044
Sc4mol	sterol-C4-methyl oxidase-like	0.044
Ppap2b	phosphatidic acid phosphatase type 2B	0.043
Acsl1	acyl-CoA synthetase long-chain family member 1	0.040
Mecom	MDS1 and EVI1 complex locus	0.039
Ccl2	chemokine (C-C motif) ligand 2	0.038
Ephx2	epoxide hydrolase 2, cytoplasmic	0.038
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.038
Apoa1	apolipoprotein A-I	0.037
Ang2	angiogenin, ribonuclease A family, member 2	0.036	Human
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.036
Klf15	Kruppel-like factor 15	0.036
Il1r1	interleukin 1 receptor, type I	0.035
Axin2	axin2	0.034
Lrp1	low density lipoprotein receptor-related protein 1	0.033
Plin4	perilipin 4	0.033
Lss	lanosterol synthase	0.033
Yipf3	Yip1 domain family, member 3	0.030
Insr	insulin receptor	0.030
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.030
Plin1	perilipin 1	0.029
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.029
Reln	reelin	0.029
Adrb3	adrenergic receptor, beta 3	0.029
Adig	adipogenin	0.028
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.027
Tbx3	T-box 3	0.026
Wasf2	WAS protein family, member 2	0.026
Idi1	isopentenyl-diphosphate delta isomerase	0.026
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.025
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.025	Human
Mrap	melanocortin 2 receptor accessory protein	0.025
Acat2	acetyl-Coenzyme A acetyltransferase 2	0.024
Orm1	orosomucoid 1	0.024
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.024
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.023	Mouse
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.023
Dgat2	diacylglycerol O-acyltransferase 2	0.023
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.023
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.023
Ces1d	carboxylesterase 1D	0.023
Tlr2	toll-like receptor 2	0.023
Lpcat3	lysophosphatidylcholine acyltransferase 3	0.022
Aacs	acetoacetyl-CoA synthetase	0.022
Scd2	stearoyl-Coenzyme A desaturase 2	0.022
Spp1	secreted phosphoprotein 1	0.022
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.022
G0s2	G0/G1 switch gene 2	0.022
Dsg4	desmoglein 4	0.021
Prkce	protein kinase C, epsilon	0.021
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.021
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.021
Ppara	peroxisome proliferator activated receptor alpha	0.021
Acly	ATP citrate lyase	0.020
Rxra	retinoid X receptor alpha	0.020
Rnase4	ribonuclease, RNase A family 4	0.020
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.020
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.019
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.019
Esr1	estrogen receptor 1 (alpha)	0.019
Mgll	monoglyceride lipase	0.019
Mt1	metallothionein 1	0.019
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.018
Por	P450 (cytochrome) oxidoreductase	0.018
Nrg4	neuregulin 4	0.018
Angptl4	angiopoietin-like 4	0.018
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.018
Pias4	protein inhibitor of activated STAT 4	0.017
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.017
Rpgrip1l	Rpgrip1-like	0.017
Prlr	prolactin receptor	0.017
Notch1	Notch gene homolog 1 (Drosophila)	0.017
Vnn3	vanin 3	0.017
Orm3	orosomucoid 3	0.017
Amy1	amylase 1, salivary	0.017
Stat3	signal transducer and activator of transcription 3	0.017
Sdsl	serine dehydratase-like	0.017
Car3	carbonic anhydrase 3	0.017
Gsta3	glutathione S-transferase, alpha 3	0.016
Gys2	glycogen synthase 2	0.016
Gnrh1	gonadotropin releasing hormone 1	0.016
Ahr	aryl-hydrocarbon receptor	0.016
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.016
Vgf	VGF nerve growth factor inducible	0.016
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.015
Samd4b	sterile alpha motif domain containing 4B	0.015
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.015
Retn	resistin	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Irs1	insulin receptor substrate 1	0.014
Epas1	endothelial PAS domain protein 1	0.014
Zfp362	zinc finger protein 362	0.014
Aqp7	aquaporin 7	0.014
Cd36	CD36 antigen	0.014	Mouse
Ces1f	carboxylesterase 1F	0.014
Htt	huntingtin	0.014
Lrp10	low-density lipoprotein receptor-related protein 10	0.014
Alas1	aminolevulinic acid synthase 1	0.014
Agtr1a	angiotensin II receptor, type 1a	0.014
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.014
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.013
Tgif2	TGFB-induced factor homeobox 2	0.013
Car5a	carbonic anhydrase 5a, mitochondrial	0.013
Slc12a6	solute carrier family 12, member 6	0.013
Lmf1	lipase maturation factor 1	0.013
Pex11a	peroxisomal biogenesis factor 11 alpha	0.013
Cfd	complement factor D (adipsin)	0.013
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.013
Trim8	tripartite motif-containing 8	0.013
Pygl	liver glycogen phosphorylase	0.013
Ncoa3	nuclear receptor coactivator 3	0.013
Rxrg	retinoid X receptor gamma	0.013
Sf1	splicing factor 1	0.013
Gm6484	predicted gene 6484	0.013
Clock	circadian locomotor output cycles kaput	0.013
Epn1	epsin 1	0.013
Sept5	septin 5	0.013
Spen	SPEN homolog, transcriptional regulator (Drosophila)	0.013
Otx2	orthodenticle homolog 2 (Drosophila)	0.012
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.012
Sgpl1	sphingosine phosphate lyase 1	0.012
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.012
Fmo1	flavin containing monooxygenase 1	0.012
Ssbp4	single stranded DNA binding protein 4	0.012
Gsk3b	glycogen synthase kinase 3 beta	0.012
Stard4	StAR-related lipid transfer (START) domain containing 4	0.012
Pim3	proviral integration site 3	0.012
Tmem45b	transmembrane protein 45b	0.012
Ang4	angiogenin, ribonuclease A family, member 4	0.012	Human
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.012
Slc22a3	solute carrier family 22 (organic cation transporter), member 3	0.012
Plxna2	plexin A2	0.012
Lepr	leptin receptor	0.012
Hic1	hypermethylated in cancer 1	0.012
Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	0.012
Mettl7b	methyltransferase like 7B	0.011
Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	0.011
Cd59a	CD59a antigen	0.011
Aco1	aconitase 1	0.011
Numb	numb gene homolog (Drosophila)	0.011
Apob	apolipoprotein B	0.011
Dctn1	dynactin 1	0.011
Ptms	parathymosin	0.011
Plin5	perilipin 5	0.011
Pon1	paraoxonase 1	0.011
Inmt	indolethylamine N-methyltransferase	0.011
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.011
Itgb4	integrin beta 4	0.011
Dab2ip	disabled homolog 2 (Drosophila) interacting protein	0.011
Abcd3	ATP-binding cassette, sub-family D (ALD), member 3	0.011
Lyz2	lysozyme 2	0.011
Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	0.011
Hp	haptoglobin	0.011
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.011
Clcn6	chloride channel 6	0.010
Fads2	fatty acid desaturase 2	0.010
Orm2	orosomucoid 2	0.010
Hnf4a	hepatic nuclear factor 4, alpha	0.010
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.010
Fah	fumarylacetoacetate hydrolase	0.010
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.010
Vps37b	vacuolar protein sorting 37B (yeast)	0.010
Fabp1	fatty acid binding protein 1, liver	0.010
Pvrl2	poliovirus receptor-related 2	0.010
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.010
Aifm2	apoptosis-inducing factor, mitochondrion-associated 2	0.010