IMP

Process View

Mus musculus

11 genes annotated in mouse

facial nerve morphogenesis

The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "facial nerve morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "facial nerve morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	1.000
Vegfa	vascular endothelial growth factor A	1.000
Eya1	eyes absent 1 homolog (Drosophila)	1.000
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.998	Mouse
Hoxa1	homeobox A1	0.996
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.989
Ednra	endothelin receptor type A	0.983
Otx2	orthodenticle homolog 2 (Drosophila)	0.973
Tbx1	T-box 1	0.966
Pax2	paired box gene 2	0.955
Tcfap2a	transcription factor AP-2, alpha	0.937
Hoxa3	homeobox A3	0.882
Hoxa2	homeobox A2	0.871	Mouse
Rarg	retinoic acid receptor, gamma	0.849
Prrx1	paired related homeobox 1	0.741
Egr2	early growth response 2	0.731
Hoxd3	homeobox D3	0.722
Nrp1	neuropilin 1	0.669
Isl1	ISL1 transcription factor, LIM/homeodomain	0.659
Pax3	paired box gene 3	0.648
Gbx2	gastrulation brain homeobox 2	0.630
Hoxb3	homeobox B3	0.626
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.598
Hoxb1	homeobox B1	0.569
Shh	sonic hedgehog	0.536
Plxnd1	plexin D1	0.516	Mouse
Plxna1	plexin A1	0.500	Mouse
Fgf3	fibroblast growth factor 3	0.451
Fgf10	fibroblast growth factor 10	0.436
Nrp2	neuropilin 2	0.427
Fgf8	fibroblast growth factor 8	0.422
Msx1	homeobox, msh-like 1	0.374
Dlx5	distal-less homeobox 5	0.309
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.284
Nab2	Ngfi-A binding protein 2	0.277
Gdnf	glial cell line derived neurotrophic factor	0.272
Hoxb2	homeobox B2	0.247
Bcl2	B-cell leukemia/lymphoma 2	0.245
Lhx9	LIM homeobox protein 9	0.241
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.233
Phox2b	paired-like homeobox 2b	0.232
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.218	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.214
Dlx2	distal-less homeobox 2	0.202
Epha4	Eph receptor A4	0.180
Rarb	retinoic acid receptor, beta	0.177
Gsc	goosecoid homeobox	0.170
Emx2	empty spiracles homolog 2 (Drosophila)	0.163
Otx1	orthodenticle homolog 1 (Drosophila)	0.161
Lama5	laminin, alpha 5	0.158
Pbx1	pre B-cell leukemia transcription factor 1	0.149
Ntf3	neurotrophin 3	0.149
Pitx2	paired-like homeodomain transcription factor 2	0.141
Ece1	endothelin converting enzyme 1	0.138
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.136
Fzd1	frizzled homolog 1 (Drosophila)	0.126
Fgfr2	fibroblast growth factor receptor 2	0.125
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.123
Hoxb4	homeobox B4	0.106
Foxg1	forkhead box G1	0.103
Hmx3	H6 homeobox 3	0.102
Msx2	homeobox, msh-like 2	0.098
Junb	Jun-B oncogene	0.096
Hoxa11	homeobox A11	0.091
Gli3	GLI-Kruppel family member GLI3	0.091
Chrd	chordin	0.091
Itga3	integrin alpha 3	0.088
Lhx1	LIM homeobox protein 1	0.086
Nes	nestin	0.084
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.084
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.082
Ret	ret proto-oncogene	0.082
Nog	noggin	0.078
Dlg4	discs, large homolog 4 (Drosophila)	0.077
Zic2	zinc finger protein of the cerebellum 2	0.073
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.071
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.071
Htt	huntingtin	0.070
Pax6	paired box gene 6	0.069
Flt1	FMS-like tyrosine kinase 1	0.068
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.066
Ptgs2	prostaglandin-endoperoxide synthase 2	0.066
Col4a3	collagen, type IV, alpha 3	0.061
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.059
Bnc1	basonuclin 1	0.058
Foxc2	forkhead box C2	0.057
Grb10	growth factor receptor bound protein 10	0.053
Pcdh12	protocadherin 12	0.052
Btg2	B-cell translocation gene 2, anti-proliferative	0.052
Rara	retinoic acid receptor, alpha	0.048
Gata3	GATA binding protein 3	0.048
Fos	FBJ osteosarcoma oncogene	0.047
Tbx10	T-box 10	0.047
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.045
Ddr2	discoidin domain receptor family, member 2	0.043
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.041
Ltbp1	latent transforming growth factor beta binding protein 1	0.041
Dach1	dachshund 1 (Drosophila)	0.041
Hand2	heart and neural crest derivatives expressed transcript 2	0.040
Pitx1	paired-like homeodomain transcription factor 1	0.039
Gdf11	growth differentiation factor 11	0.039
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.039
Hoxd11	homeobox D11	0.038
Mid2	midline 2	0.038
Tlx3	T-cell leukemia, homeobox 3	0.037
En2	engrailed 2	0.036
Fgfr1	fibroblast growth factor receptor 1	0.035
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.035
Ebf3	early B-cell factor 3	0.034
Myf5	myogenic factor 5	0.034
Plxna4	plexin A4	0.033
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.032
Hoxa4	homeobox A4	0.031
Tbx15	T-box 15	0.031
Etl4	enhancer trap locus 4	0.031
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.030
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.029
Hoxd1	homeobox D1	0.029	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.029
Hand1	heart and neural crest derivatives expressed transcript 1	0.029
Cdh13	cadherin 13	0.028
Rgnef	Rho-guanine nucleotide exchange factor	0.028
Fbln1	fibulin 1	0.028
Fgf18	fibroblast growth factor 18	0.028
Bdnf	brain derived neurotrophic factor	0.027
Wnt1	wingless-related MMTV integration site 1	0.026
Hmx2	H6 homeobox 2	0.026
Nynrin	NYN domain and retroviral integrase containing	0.026
Nanog	Nanog homeobox	0.026
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.025	Mouse
Bcl6b	B-cell CLL/lymphoma 6, member B	0.025
Pax7	paired box gene 7	0.025
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.025
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.025
Pax8	paired box gene 8	0.024
Eya4	eyes absent 4 homolog (Drosophila)	0.024
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.024
Foxc1	forkhead box C1	0.024
Pou3f3	POU domain, class 3, transcription factor 3	0.023
Mecom	MDS1 and EVI1 complex locus	0.023
Nrg1	neuregulin 1	0.022
Pou4f2	POU domain, class 4, transcription factor 2	0.022
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.022
Smo	smoothened homolog (Drosophila)	0.022
Sdc3	syndecan 3	0.022
Sim2	single-minded homolog 2 (Drosophila)	0.021
Phldb1	pleckstrin homology-like domain, family B, member 1	0.021
Myo1e	myosin IE	0.021
Bcar1	breast cancer anti-estrogen resistance 1	0.021
Ccdc24	coiled-coil domain containing 24	0.021
En1	engrailed 1	0.021
Foxi3	forkhead box I3	0.020
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.020
Lamc1	laminin, gamma 1	0.020
Ripply3	ripply3 homolog (zebrafish)	0.020
Mmp15	matrix metallopeptidase 15	0.019
Lrp1	low density lipoprotein receptor-related protein 1	0.019
Smad3	MAD homolog 3 (Drosophila)	0.019
Foxd2	forkhead box D2	0.019
Hoxb8	homeobox B8	0.019
Sox2	SRY-box containing gene 2	0.018
Lhx3	LIM homeobox protein 3	0.018
Apc2	adenomatosis polyposis coli 2	0.018
Meox1	mesenchyme homeobox 1	0.018
Neurog1	neurogenin 1	0.018
Pdgfb	platelet derived growth factor, B polypeptide	0.018
Sox11	SRY-box containing gene 11	0.017
Aif1l	allograft inflammatory factor 1-like	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Nab1	Ngfi-A binding protein 1	0.017
Sox7	SRY-box containing gene 7	0.017
Fign	fidgetin	0.017
Matn3	matrilin 3	0.016
Efnb2	ephrin B2	0.016
Lama1	laminin, alpha 1	0.016
Col4a6	collagen, type IV, alpha 6	0.016
Fgfr4	fibroblast growth factor receptor 4	0.016
Pou3f4	POU domain, class 3, transcription factor 4	0.016
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.015
Tead3	TEA domain family member 3	0.015
Efna2	ephrin A2	0.015
Tcf15	transcription factor 15	0.015
Hoxb5	homeobox B5	0.015
Ednrb	endothelin receptor type B	0.015
Hapln1	hyaluronan and proteoglycan link protein 1	0.015
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.015
Shroom1	shroom family member 1	0.014
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.014
Hoxa5	homeobox A5	0.014
Wnt9b	wingless-type MMTV integration site 9B	0.014
Hmx1	H6 homeobox 1	0.014
Pdgfa	platelet derived growth factor, alpha	0.014
Cachd1	cache domain containing 1	0.014
Fosb	FBJ osteosarcoma oncogene B	0.014
Cdk14	cyclin-dependent kinase 14	0.014
Ptrf	polymerase I and transcript release factor	0.014
Aplnr	apelin receptor	0.014
Ephb3	Eph receptor B3	0.014
Tcf21	transcription factor 21	0.014
Hgf	hepatocyte growth factor	0.013
Hip1	huntingtin interacting protein 1	0.013
Msi1	Musashi homolog 1(Drosophila)	0.013
Hoxc6	homeobox C6	0.013
Zfhx4	zinc finger homeodomain 4	0.013
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.013
Zfp503	zinc finger protein 503	0.013
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.013	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.013
Hoxb6	homeobox B6	0.012
Ugt8a	UDP galactosyltransferase 8A	0.012
Notch3	Notch gene homolog 3 (Drosophila)	0.012
Ctf1	cardiotrophin 1	0.012
Hoxa7	homeobox A7	0.012
Mrc2	mannose receptor, C type 2	0.012
Mkl2	MKL/myocardin-like 2	0.012
Adamtsl5	ADAMTS-like 5	0.012
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.012
Chst2	carbohydrate sulfotransferase 2	0.012
Zfp185	zinc finger protein 185	0.012
Mgat3	mannoside acetylglucosaminyltransferase 3	0.012
Fjx1	four jointed box 1 (Drosophila)	0.012
Npr1	natriuretic peptide receptor 1	0.012
Tbx2	T-box 2	0.012
Lrp2	low density lipoprotein receptor-related protein 2	0.012
Dock4	dedicator of cytokinesis 4	0.012
Efs	embryonal Fyn-associated substrate	0.011
Notch4	Notch gene homolog 4 (Drosophila)	0.011
Tulp1	tubby like protein 1	0.011
Pcdh1	protocadherin 1	0.011
Wnt10b	wingless related MMTV integration site 10b	0.011
Tspan9	tetraspanin 9	0.011
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.011
Angpt1	angiopoietin 1	0.011
Capn6	calpain 6	0.011
Fosl2	fos-like antigen 2	0.011
Ephb4	Eph receptor B4	0.011
Tbx3	T-box 3	0.011
Srf	serum response factor	0.011
Efna4	ephrin A4	0.011
Nckap5l	NCK-associated protein 5-like	0.011
Epha2	Eph receptor A2	0.011
Acvr1	activin A receptor, type 1	0.011
Cabp7	calcium binding protein 7	0.011
Bmp5	bone morphogenetic protein 5	0.010
Sox10	SRY-box containing gene 10	0.010
Efna5	ephrin A5	0.010
Adamts10	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10	0.010
Trim62	tripartite motif-containing 62	0.010
Fzd2	frizzled homolog 2 (Drosophila)	0.010