IMP
Process View
positive regulation of ras gtpase activity
Any process that activates or increases the activity of a GTPase of the Ras superfamily.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of ras gtpase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Nckap1 | NCK-associated protein 1 | 0.184 | ||
| Dock9 | dedicator of cytokinesis 9 | 0.088 | Mouse | |
| Kit | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.067 | ||
| Git1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.062 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.057 | ||
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.056 | ||
| Tle4 | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 0.054 | ||
| Anxa2 | annexin A2 | 0.052 | ||
| Stxbp5 | syntaxin binding protein 5 (tomosyn) | 0.051 | Rat | |
| Dlg3 | discs, large homolog 3 (Drosophila) | 0.047 | ||
| Bin2 | bridging integrator 2 | 0.045 | ||
| LOC100364212 | heterogeneous nuclear ribonucleoprotein K-like | 0.042 | ||
| Tek | TEK tyrosine kinase, endothelial | 0.041 | ||
| Fmnl1 | formin-like 1 | 0.040 | ||
| Ylpm1 | YLP motif containing 1 | 0.039 | ||
| Atf3 | activating transcription factor 3 | 0.038 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.037 | ||
| Adar | adenosine deaminase, RNA-specific | 0.036 | ||
| Arpc5 | actin related protein 2/3 complex, subunit 5 | 0.034 | ||
| Macf1 | microtubule-actin crosslinking factor 1 | 0.034 | ||
| Smg5 | Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) | 0.034 | ||
| Plcg1 | phospholipase C, gamma 1 | 0.033 | ||
| Cyth1 | cytohesin 1 | 0.032 | ||
| Sbf1 | SET binding factor 1 | 0.031 | Fly | |
| Itpr1 | inositol 1,4,5-triphosphate receptor, type 1 | 0.030 | ||
| Pld2 | phospholipase D2 | 0.030 | ||
| Rab3il1 | RAB3A interacting protein (rabin3)-like 1 | 0.029 | ||
| Zfp36 | zinc finger protein 36 | 0.028 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.027 | ||
| Mllt4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.026 | ||
| Klf6 | Kruppel-like factor 6 | 0.026 | ||
| Anxa1 | annexin A1 | 0.026 | ||
| Cfp | complement factor properdin | 0.025 | ||
| Gpr116 | G protein-coupled receptor 116 | 0.025 | ||
| Pik3cd | phosphoinositide-3-kinase, catalytic, delta polypeptide | 0.025 | ||
| Vps52 | vacuolar protein sorting 52 homolog (S. cerevisiae) | 0.025 | ||
| Pde2a | phosphodiesterase 2A, cGMP-stimulated | 0.024 | ||
| Shank3 | SH3 and multiple ankyrin repeat domains 3 | 0.024 | ||
| Hk1 | hexokinase 1 | 0.024 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A, isoform 2 | 0.023 | ||
| Fam108a1 | family with sequence similarity 108, member A1 | 0.023 | ||
| Plxnd1 | plexin D1 | 0.023 | ||
| Arhgef11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.023 | Fly | |
| Junb | jun B proto-oncogene | 0.023 | ||
| Prkcb | protein kinase C, beta | 0.023 | ||
| Kif16b | kinesin family member 16B | 0.022 | ||
| Rap1b | RAP1B, member of RAS oncogene family | 0.022 | Rat | |
| Add3 | adducin 3 (gamma) | 0.022 | ||
| Strn | striatin, calmodulin binding protein | 0.022 | ||
| Pi4ka | phosphatidylinositol 4-kinase, catalytic, alpha | 0.022 | ||
| Abr | active BCR-related gene | 0.022 | ||
| Gnai3 | guanine nucleotide binding protein (G protein), alpha inhibiting 3 | 0.022 | ||
| Jak1 | Janus kinase 1 | 0.021 | ||
| Opcml | opioid binding protein/cell adhesion molecule-like | 0.021 | ||
| Galnt10 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) | 0.021 | ||
| Arpc2 | actin related protein 2/3 complex, subunit 2 | 0.021 | ||
| Cacna1a | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.021 | ||
| Mmp17 | matrix metallopeptidase 17 | 0.021 | ||
| LOC100360150 | eukaryotic translation elongation factor 1 alpha 2 | 0.021 | ||
| Sirpa | signal-regulatory protein alpha | 0.021 | ||
| Arhgap4 | Rho GTPase activating protein 4 | 0.021 | ||
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.021 | ||
| Mcf2l | MCF.2 cell line derived transforming sequence-like | 0.021 | Mouse | |
| Coro2b | coronin, actin binding protein, 2B | 0.021 | ||
| Cyyr1 | cysteine/tyrosine-rich 1 | 0.021 | ||
| Unc13b | unc-13 homolog B (C. elegans) | 0.021 | ||
| Bspry | B-box and SPRY domain containing | 0.021 | ||
| Dok1 | docking protein 1 | 0.020 | ||
| Rara | retinoic acid receptor, alpha | 0.020 | ||
| Ccdc85b | coiled-coil domain containing 85B | 0.020 | ||
| Clcn7 | chloride channel 7 | 0.020 | ||
| Fnbp1 | formin binding protein 1 | 0.020 | ||
| Gria2 | glutamate receptor, ionotropic, AMPA 2 | 0.020 | ||
| Lcp2 | lymphocyte cytosolic protein 2 | 0.019 | ||
| Cdc34 | cell division cycle 34 homolog (S. cerevisiae) | 0.019 | ||
| S100a4 | S100 calcium-binding protein A4 | 0.019 | ||
| Ciita | class II, major histocompatibility complex, transactivator | 0.019 | ||
| Plekha6 | pleckstrin homology domain containing, family A member 6 | 0.019 | ||
| Prkch | protein kinase C, eta | 0.019 | ||
| Syn2 | synapsin II | 0.019 | ||
| Fgd2 | FYVE, RhoGEF and PH domain containing 2 | 0.018 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.018 | ||
| Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.018 | ||
| Ssh3 | slingshot homolog 3 (Drosophila) | 0.018 | ||
| Capn2 | calpain 2 | 0.018 | ||
| Pik3r2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.018 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.018 | ||
| Epb41l1 | erythrocyte membrane protein band 4.1-like 1 | 0.018 | ||
| LOC691920 | similar to kinesin-like motor protein C20orf23 | 0.018 | ||
| Tspan18 | tetraspanin 18 | 0.018 | ||
| Gadd45gip1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 0.018 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.017 | ||
| Lphn2 | latrophilin 2 | 0.017 | ||
| Ppfibp1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.017 | ||
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.017 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.017 | ||
| Shank2 | SH3 and multiple ankyrin repeat domains 2 | 0.017 | ||
| RGD621098 | similar to RIKEN cDNA D230025D16Rik | 0.017 | ||
| Abi3 | ABI family, member 3 | 0.017 | ||
| Ppp2ca | protein phosphatase 2, catalytic subunit, alpha isoform | 0.016 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.016 | ||
| Synrg | synergin, gamma | 0.016 | ||
| Inpp4a | inositol polyphosphate-4-phosphatase, type 1 | 0.016 | ||
| Ptafr | platelet-activating factor receptor | 0.016 | ||
| Arf4 | ADP-ribosylation factor 4 | 0.016 | ||
| Zmym4 | zinc finger, MYM-type 4 | 0.016 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.016 | ||
| Picalm | phosphatidylinositol binding clathrin assembly protein | 0.016 | ||
| Extl3 | exostoses (multiple)-like 3 | 0.016 | ||
| Copb1 | coatomer protein complex, subunit beta 1 | 0.015 | ||
| Dapk3 | death-associated protein kinase 3 | 0.015 | ||
| Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.015 | ||
| Pja2 | praja 2, RING-H2 motif containing | 0.015 | ||
| Utrn | utrophin | 0.015 | ||
| Gnai1 | guanine nucleotide binding protein (G protein), alpha inhibiting 1 | 0.015 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.015 | ||
| Irf5 | interferon regulatory factor 5 | 0.015 | ||
| Ptprm | protein tyrosine phosphatase, receptor type, M | 0.015 | ||
| Ptprs | protein tyrosine phosphatase, receptor type, S | 0.015 | ||
| Vamp3 | vesicle-associated membrane protein 3 | 0.015 | ||
| Dnm2 | dynamin 2 | 0.015 | ||
| Smek2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) | 0.015 | ||
| Map4k1 | mitogen activated protein kinase kinase kinase kinase 1 | 0.015 | ||
| Apc | adenomatous polyposis coli | 0.015 | ||
| Scamp1 | secretory carrier membrane protein 1 | 0.015 | ||
| Jak2 | Janus kinase 2 | 0.015 | ||
| Fgfr1 | Fibroblast growth factor receptor 1 | 0.015 | ||
| Vav1 | vav 1 guanine nucleotide exchange factor | 0.015 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.015 | ||
| Cd200r1 | CD200 receptor 1 | 0.015 | ||
| Cachd1 | cache domain containing 1 | 0.015 | ||
| Pctk1 | PCTAIRE protein kinase 1 | 0.014 | ||
| Cx3cl1 | chemokine (C-X3-C motif) ligand 1 | 0.014 | ||
| Adrbk1 | adrenergic, beta, receptor kinase 1 | 0.014 | ||
| Cstb | cystatin B (stefin B) | 0.014 | ||
| Ddn | dendrin | 0.014 | ||
| Dnaja4 | DnaJ (Hsp40) homolog, subfamily A, member 4 | 0.014 | ||
| Zfp238 | zinc finger protein 238 | 0.014 | ||
| Stk39 | serine/threonine kinase 39, STE20/SPS1 homolog (yeast) | 0.014 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.014 | ||
| Adcy5 | adenylate cyclase 5 | 0.014 | ||
| Sh2d3c | SH2 domain containing 3C | 0.014 | ||
| Pdgfb | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.014 | ||
| Apbb1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.014 | ||
| Notch1 | Notch homolog 1, translocation-associated (Drosophila) | 0.014 | ||
| Stk10 | serine/threonine kinase 10 | 0.013 | ||
| Hand2 | heart and neural crest derivatives expressed 2 | 0.013 | ||
| Prkcd | protein kinase C, delta | 0.013 | ||
| Lrrc16a | leucine rich repeat containing 16A | 0.013 | ||
| Hspa12b | heat shock protein 12B | 0.013 | ||
| Usp28 | ubiquitin specific peptidase 28 | 0.013 | ||
| Sulf1 | sulfatase 1 | 0.013 | ||
| Sept4 | septin 4 | 0.013 | ||
| Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.013 | ||
| Pik3r3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.013 | ||
| Sdcbp | syndecan binding protein | 0.013 | ||
| Bcas1 | breast carcinoma amplified sequence 1 | 0.013 | ||
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.013 | ||
| Sox17 | SRY (sex determining region Y)-box 17 | 0.013 | ||
| Cugbp2 | CUG triplet repeat, RNA binding protein 2 | 0.013 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.013 | ||
| RGD1562291 | similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2) | 0.013 | ||
| Garnl4 | GTPase activating Rap/RanGAP domain-like 4 | 0.013 | Mouse | |
| Lzts2 | leucine zipper, putative tumor suppressor 2 | 0.013 | ||
| Mapk8ip3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.013 | ||
| Sipa1 | signal-induced proliferation-associated 1 | 0.013 | ||
| Sh3kbp1 | SH3-domain kinase binding protein 1 | 0.013 | ||
| Hmha1 | histocompatibility (minor) HA-1 | 0.013 | ||
| Med23 | mediator complex subunit 23 | 0.013 | ||
| Fgd5 | FYVE, RhoGEF and PH domain containing 5 | 0.013 | ||
| Serinc5 | serine incorporator 5 | 0.013 | ||
| Tomm34 | translocase of outer mitochondrial membrane 34 | 0.013 | ||
| Cntn1 | contactin 1 | 0.012 | ||
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.012 | ||
| RGD1563106 | similar to novel protein | 0.012 | ||
| Abcg1 | ATP-binding cassette, subfamily G (WHITE), member 1 | 0.012 | ||
| Lgals3 | lectin, galactoside-binding, soluble, 3 | 0.012 | ||
| Pou3f1 | POU class 3 homeobox 1 | 0.012 | ||
| Ablim2 | actin binding LIM protein family, member 2 | 0.012 | ||
| Usp40 | ubiquitin specific peptidase 40 | 0.012 | ||
| Pgp | phosphoglycolate phosphatase | 0.012 | ||
| Itgb7 | integrin, beta 7 | 0.012 | ||
| Unc13d | unc-13 homolog D (C. elegans) | 0.012 | ||
| Akap1 | A kinase (PRKA) anchor protein 1 | 0.012 | ||
| Thrb | thyroid hormone receptor beta | 0.012 | ||
| Rasgrp3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | 0.012 | Human | |
| Fam113b | family with sequence similarity 113, member B | 0.012 | ||
| Pip4k2b | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.012 | ||
| Pctk2 | PCTAIRE protein kinase 2 | 0.012 | ||
| Prdm4 | PR domain containing 4 | 0.012 | ||
| Anapc5 | anaphase-promoting complex subunit 5 | 0.012 | ||
| Ube3b | ubiquitin protein ligase E3B | 0.012 | ||
| Kremen1 | kringle containing transmembrane protein 1 | 0.012 | ||
| Trerf1 | transcriptional regulating factor 1 | 0.012 | ||
| Pragmin | pragma of Rnd2 | 0.012 | ||
| Ptprz1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.012 | ||
| Egr1 | early growth response 1 | 0.012 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.012 | ||
| Lrrc33 | leucine rich repeat containing 33 | 0.012 | ||
| Arhgap5 | Rho GTPase activating protein 5 | 0.012 | ||
| Tle2 | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | 0.012 | ||
| Agrn | agrin | 0.012 | ||
| Hdac7 | histone deacetylase 7 | 0.012 | ||
| Tnfrsf14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.012 | ||
| Bbx | bobby sox homolog (Drosophila) | 0.011 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.011 | ||
| Znrf2 | zinc and ring finger 2 | 0.011 | ||
| Grasp | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | 0.011 | ||
| Capn5 | calpain 5 | 0.011 | ||
| Cyfip2 | cytoplasmic FMR1 interacting protein 2 | 0.011 | ||
| Clcn2 | chloride channel 2 | 0.011 | ||
| Cr1l | complement component (3b/4b) receptor 1-like | 0.011 | ||
| Ap3m2 | adaptor-related protein complex 3, mu 2 subunit | 0.011 | ||
| Psd4 | pleckstrin and Sec7 domain containing 4 | 0.011 | ||
| Fos | FBJ osteosarcoma oncogene | 0.011 | ||
| Rab25 | RAB25, member RAS oncogene family | 0.011 | ||
| Ep400 | E1A binding protein p400 | 0.011 | ||
| Acvrl1 | activin A receptor type II-like 1 | 0.011 | ||
| Plxdc1 | plexin domain containing 1 | 0.011 | ||
| Meis1 | Meis homeobox 1 | 0.011 | ||
| Shroom1 | shroom family member 1 | 0.011 | ||
| Sdc3 | syndecan 3 | 0.011 | ||
| Phlpp1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.011 | ||
| Pum1 | pumilio homolog 1 (Drosophila) | 0.011 | ||
| Fkbp8 | FK506 binding protein 8 | 0.011 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.011 | ||
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.011 | ||
| Ctdspl | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.011 | ||
| Phc1 | polyhomeotic homolog 1 (Drosophila) | 0.011 | ||
| Kcnab1 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.011 | ||
| Mef2a | myocyte enhancer factor 2a | 0.011 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B (zinc finger protein) | 0.011 | ||
| Clasp1 | cytoplasmic linker associated protein 1 | 0.011 | ||
| Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.011 | ||
| S1pr5 | sphingosine-1-phosphate receptor 5 | 0.011 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.011 | ||
| Schip1 | schwannomin interacting protein 1 | 0.011 | ||
| Ptk2b | PTK2B protein tyrosine kinase 2 beta | 0.011 | ||
| Il17re | interleukin 17 receptor E | 0.011 | ||
| Smc3 | structural maintenance of chromosomes 3 | 0.011 | ||
| Pip4k2a | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.011 | ||
| Apbb1ip | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | 0.011 | ||
| Sipa1l1 | signal-induced proliferation-associated 1 like 1 | 0.011 | ||
| Samd14 | sterile alpha motif domain containing 14 | 0.011 | ||
| Epn1 | Epsin 1 | 0.011 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.011 | ||
| Zc3h7b | zinc finger CCCH-type containing 7B | 0.011 | ||
| Cd37 | CD37 molecule | 0.011 | ||
| Ksr1 | kinase suppressor of ras 1 | 0.011 | ||
| Palm | paralemmin | 0.011 | ||
| Rgl1 | ral guanine nucleotide dissociation stimulator,-like 1 | 0.011 | ||
| Pdzd2 | PDZ domain containing 2 | 0.011 | ||
| Slc45a3 | solute carrier family 45, member 3 | 0.011 | ||
| Sipa1l2 | signal-induced proliferation-associated 1 like 2 | 0.010 | Rat | |
| Invs | inversin | 0.010 | ||
| Nov | nephroblastoma overexpressed gene | 0.010 | ||
| Arpc3 | actin related protein 2/3 complex, subunit 3 | 0.010 | ||
| Plcb1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.010 | ||
| A4galt | alpha 1,4-galactosyltransferase | 0.010 | ||
| St3gal2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 0.010 | ||
| Cdc42se2 | CDC42 small effector 2 | 0.010 | ||
| Ptpn18 | protein tyrosine phosphatase, non-receptor type 18 | 0.010 | ||
| Camk2d | calcium/calmodulin-dependent protein kinase II delta | 0.010 | ||
| Flt1 | FMS-related tyrosine kinase 1 | 0.010 | ||
| Dennd2c | DENN/MADD domain containing 2C | 0.010 | Human | |
| Tmem204 | transmembrane protein 204 | 0.010 | ||
| Podxl | podocalyxin-like | 0.010 | ||
| Ldlrap1 | low density lipoprotein receptor adaptor protein 1 | 0.010 | ||
| Arhgap27 | Rho GTPase activating protein 27 | 0.010 | ||
| Evl | Enah/Vasp-like | 0.010 | ||
| Agap3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 | 0.010 | ||
| Slc24a6 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 | 0.010 | ||
| Osbpl7 | oxysterol binding protein-like 7 | 0.010 | ||
| Jdp2 | Jun dimerization protein 2 | 0.010 | ||
| Ophn1 | oligophrenin 1 | 0.010 | Mouse | |
| Scarf2 | scavenger receptor class F, member 2 | 0.010 | ||
| Rapgef3 | Rap guanine nucleotide exchange factor (GEF) 3 | 0.010 | Human Rat | |
| Elf1 | E74-like factor 1 | 0.010 | ||
| G3bp2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.010 | ||
| Farp1 | FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.010 | ||
| Rhob | ras homolog gene family, member B | 0.010 | ||
| Lmo7 | LIM domain 7 | 0.010 | ||
| Myo10 | myosin X | 0.010 | ||
| LOC687609 | similar to ras homolog gene family, member f | 0.010 |