IMP
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natural killer cell mediated immune response to tumor cell
An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
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Click on a gene's description to view its network relationships with genes known to be involved in "natural killer cell mediated immune response to tumor cell"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.991 | ||
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.816 | Rat | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.600 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.498 | ||
| Klrc2 | killer cell lectin-like receptor subfamily C, member 2 | 0.492 | Rat | |
| Igsf6 | immunoglobulin superfamily, member 6 | 0.464 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.448 | ||
| Gzmk | granzyme K | 0.442 | ||
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.402 | ||
| Il7r | interleukin 7 receptor | 0.368 | ||
| Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.341 | ||
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.286 | Rat | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.243 | Rat | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.220 | Rat | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.218 | ||
| Cd2 | Cd2 molecule | 0.198 | ||
| Gzmb | granzyme B | 0.184 | ||
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.183 | ||
| Mcpt8 | mast cell protease 8 | 0.181 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.168 | ||
| Cd8a | CD8a molecule | 0.165 | ||
| Cyp2c12 | cytochrome P450, family 2, subfamily c, polypeptide 12 | 0.159 | ||
| Clec9a | C-type lectin domain family 9, member a | 0.140 | Rat | |
| Mmp12 | matrix metallopeptidase 12 | 0.139 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.127 | ||
| LOC24906 | RoBo-1 | 0.121 | ||
| Oasl | 2'-5'-oligoadenylate synthetase-like | 0.118 | ||
| Clec12a | C-type lectin domain family 12, member A | 0.101 | ||
| Myc | myelocytomatosis oncogene | 0.100 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.096 | ||
| Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.087 | ||
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.082 | ||
| Tnfrsf12a | tumor necrosis factor receptor superfamily, member 12a | 0.081 | ||
| Tlr7 | toll-like receptor 7 | 0.080 | ||
| Pcsk1 | proprotein convertase subtilisin/kexin type 1 | 0.080 | ||
| Sell | selectin L | 0.077 | ||
| Spn | sialophorin | 0.077 | ||
| Il1rl1 | interleukin 1 receptor-like 1 | 0.077 | ||
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.075 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.072 | ||
| Slc9a4 | solute carrier family 9 (sodium/hydrogen exchanger), member 4 | 0.072 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.069 | ||
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.066 | ||
| Plaur | plasminogen activator, urokinase receptor | 0.066 | ||
| LOC300024 | similar to Ly6-B antigen gene | 0.066 | ||
| Gzmm | granzyme M (lymphocyte met-ase 1) | 0.064 | ||
| Cd72 | Cd72 molecule | 0.056 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.056 | ||
| Gucy2g | guanylate cyclase 2G | 0.051 | ||
| Ccl9 | chemokine (C-C motif) ligand 9 | 0.048 | ||
| Clec4f | C-type lectin domain family 4, member f | 0.048 | ||
| Il18r1 | interleukin 18 receptor 1 | 0.047 | ||
| Clec7a | C-type lectin domain family 7, member a | 0.046 | Rat | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.046 | ||
| Ctla2a | cytotoxic T lymphocyte-associated protein 2 alpha | 0.045 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.044 | ||
| Slamf9 | SLAM family member 9 | 0.042 | ||
| LOC689399 | hypothetical protein LOC689399 | 0.042 | ||
| Sh2d2a | SH2 domain protein 2A | 0.042 | ||
| Vom1r93 | vomeronasal 1 receptor 93 | 0.041 | ||
| Ubd | ubiquitin D | 0.041 | ||
| Tmem182 | transmembrane protein 182 | 0.040 | ||
| Rt1.aa | MHC class I RT1.Aa alpha-chain | 0.039 | ||
| Sit1 | signaling threshold regulating transmembrane adaptor 1 | 0.037 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.036 | ||
| Tcrb | T-cell receptor beta chain | 0.036 | ||
| Serpinb3a | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A | 0.036 | ||
| Vom1r102 | vomeronasal 1 receptor 102 | 0.035 | ||
| Slc13a1 | solute carrier family 13 (sodium/sulfate symporters), member 1 | 0.035 | ||
| Ugt2a1 | UDP glucuronosyltransferase 2 family, polypeptide A1 | 0.034 | ||
| Klra22 | killer cell lectin-like receptor subfamily A, member 22 | 0.034 | Rat | |
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.034 | ||
| RGD1562844 | similar to serine (or cysteine) proteinase inhibitor, clade B, member 9 | 0.033 | ||
| Tnni3k | TNNI3 interacting kinase | 0.033 | ||
| Ifng | interferon gamma | 0.032 | ||
| Igfl3 | IGF-like family member 3 | 0.032 | ||
| Fam65b | family with sequence similarity 65, member B | 0.032 | ||
| Spic | Spi-C transcription factor (Spi-1/PU.1 related) | 0.031 | ||
| Atp6v1g3 | ATPase, H+ transporting, lysosomal V1 subunit G3 | 0.030 | ||
| Oas1b | 2-5 oligoadenylate synthetase 1B | 0.028 | ||
| Rps29 | ribosomal protein S29 | 0.028 | ||
| Art2 | ADP-ribosyltransferase 2 | 0.028 | ||
| Zfp37 | zinc finger protein 37 | 0.027 | ||
| Scin | scinderin | 0.027 | ||
| Mos | Moloney sarcoma oncogene | 0.026 | ||
| Lrrc8c | leucine rich repeat containing 8 family, member C | 0.025 | ||
| Il6 | interleukin 6 | 0.025 | ||
| Stx11 | syntaxin 11 | 0.025 | ||
| Txnrd1 | thioredoxin reductase 1 | 0.024 | ||
| Irf2 | interferon regulatory factor 2 | 0.024 | ||
| Atf3 | activating transcription factor 3 | 0.023 | ||
| Mcpt4 | mast cell protease 4 | 0.023 | ||
| Samsn1 | SAM domain, SH3 domain and nuclear localization signals, 1 | 0.023 | ||
| Pou1f1 | POU class 1 homeobox 1 | 0.023 | ||
| Cd69 | Cd69 molecule | 0.023 | Rat | |
| Slfn3 | schlafen 3 | 0.022 | ||
| Nox4 | NADPH oxidase 4 | 0.022 | ||
| Dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) | 0.022 | ||
| Unc5cl | unc-5 homolog C (C. elegans)-like | 0.022 | ||
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.022 | ||
| Prl2a1 | Prolactin family 2, subfamily a, member 1 | 0.022 | ||
| LOC494538 | ABP beta | 0.022 | ||
| Itgad | integrin, alpha D | 0.021 | ||
| Gimap6 | GTPase, IMAP family member 6 | 0.020 | ||
| Cxcl11 | chemokine (C-X-C motif) ligand 11 | 0.020 | ||
| Gfra3 | GDNF family receptor alpha 3 | 0.020 | ||
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.020 | ||
| Btg2 | BTG family, member 2 | 0.020 | ||
| Reg3g | regenerating islet-derived 3 gamma | 0.020 | ||
| Slc22a25 | solute carrier family 22, member 25 | 0.019 | ||
| Gpr114 | G protein-coupled receptor 114 | 0.019 | ||
| Prl8a7 | prolactin family 8, subfamily a, member 7 | 0.019 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A | 0.019 | ||
| Skap1 | src kinase associated phosphoprotein 1 | 0.019 | ||
| Spink1 | serine peptidase inhibitor, Kazal type 1 | 0.019 | ||
| Cd3g | CD3 molecule, gamma | 0.019 | ||
| Tfec | transcription factor EC | 0.018 | ||
| Stfa2l3 | stefin A2-like 3 | 0.018 | ||
| Havcr1 | hepatitis A virus cellular receptor 1 | 0.018 | ||
| Ctsj | cathepsin J | 0.018 | ||
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.018 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.018 | ||
| Dok2 | docking protein 2 | 0.018 | ||
| Chrm5 | cholinergic receptor, muscarinic 5 | 0.018 | ||
| Cd244 | Cd244 molecule, natural killer cell receptor 2B4 | 0.018 | ||
| Gem | GTP binding protein (gene overexpressed in skeletal muscle) | 0.018 | ||
| Prl2b1 | Prolactin family 2, subfamily b, member 1 | 0.017 | ||
| Ambn | ameloblastin | 0.017 | ||
| LOC690020 | similar to killer cell lectin-like receptor, subfamily A, member 17 | 0.017 | Rat | |
| Pik3cd | phosphoinositide-3-kinase, catalytic, delta polypeptide | 0.016 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.016 | ||
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.016 | ||
| Cd247 | Cd247 molecule | 0.016 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.016 | ||
| Bcl10 | B-cell CLL/lymphoma 10 | 0.016 | ||
| Spef2 | sperm flagellar 2 | 0.016 | ||
| Srxn1 | sulfiredoxin 1 homolog (S. cerevisiae) | 0.016 | ||
| Parvg | parvin, gamma | 0.015 | ||
| Ms4a7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.015 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.015 | ||
| Myocd | myocardin | 0.015 | ||
| Gzma | granzyme A | 0.015 | ||
| LOC100362325 | rCG28200-like | 0.015 | ||
| Zpbp2 | zona pellucida binding protein 2 | 0.015 | ||
| Gpr64 | G protein-coupled receptor 64 | 0.015 | ||
| Olr1226 | olfactory receptor 1226 | 0.015 | ||
| MGC105649 | hypothetical LOC302884 | 0.015 | ||
| Stab2 | stabilin 2 | 0.015 | ||
| Reg3b | regenerating islet-derived 3 beta | 0.015 | ||
| Ifrd1 | interferon-related developmental regulator 1 | 0.015 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.015 | ||
| Cd200r2 | Cd200 receptor 2 | 0.015 | ||
| Sh2d1a | SH2 domain protein 1A | 0.014 | ||
| RGD1311300 | similar to T cell receptor V delta 6 | 0.014 | ||
| Gimap4 | GTPase, IMAP family member 4 | 0.014 | ||
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.014 | ||
| Epsti1 | epithelial stromal interaction 1 (breast) | 0.014 | ||
| Slc12a1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1 | 0.014 | ||
| S100vp | S100 calcium-binding protein, ventral prostate | 0.014 | ||
| Fcgr1a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 0.014 | ||
| C7 | complement component 7 | 0.014 | ||
| Sdc1 | syndecan 1 | 0.013 | ||
| Klrb1a | killer cell lectin-like receptor subfamily B, member 1A | 0.013 | ||
| LOC100361765 | homeobox B2 | 0.013 | ||
| LOC100361053 | mCG1039741-like | 0.013 | ||
| Tmigd1 | transmembrane and immunoglobulin domain containing 1 | 0.013 | ||
| Hbegf | heparin-binding EGF-like growth factor | 0.013 | ||
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.013 | ||
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.013 | ||
| Cst7 | cystatin F (leukocystatin) | 0.013 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.012 | ||
| Sval2 | seminal vesicle antigen-like 2 | 0.012 | ||
| Tas2r105 | taste receptor, type 2, member 105 | 0.012 | ||
| Ptprcap | protein tyrosine phosphatase, receptor type, C-associated protein | 0.012 | ||
| Slco1b3 | solute carrier organic anion transporter family, member 1b3 | 0.012 | ||
| Rhoh | ras homolog gene family, member H | 0.012 | ||
| Sgms2 | sphingomyelin synthase 2 | 0.012 | ||
| Cyp7b1 | cytochrome P450, family 7, subfamily b, polypeptide 1 | 0.012 | ||
| Gpx2 | glutathione peroxidase 2 | 0.012 | ||
| Dpp4 | dipeptidylpeptidase 4 | 0.012 | ||
| Gadd45a | growth arrest and DNA-damage-inducible, alpha | 0.012 | ||
| Krtap13-2 | keratin associated protein 13-2 | 0.012 | ||
| Myct1 | myc target 1 | 0.012 | ||
| RT1-A3 | RT1 class I, locus A3 | 0.011 | ||
| Odf4 | outer dense fiber of sperm tails 4 | 0.011 | ||
| Stap1 | signal transducing adaptor family member 1 | 0.011 | ||
| Ccl21 | chemokine (C-C motif) ligand 21 | 0.011 | ||
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.011 | ||
| Cd22 | CD22 molecule | 0.011 | ||
| Fcrla | Fc receptor-like A | 0.011 | ||
| LOC685157 | similar to paired immunoglobin-like type 2 receptor beta | 0.011 | ||
| Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.011 | ||
| Fnbp1 | formin binding protein 1 | 0.011 | ||
| Tnfrsf14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.011 | ||
| Fcnb | ficolin B | 0.011 | ||
| Cst5 | cystatin D | 0.011 | ||
| C6 | complement component 6 | 0.011 | ||
| Map4k2 | mitogen activated protein kinase kinase kinase kinase 2 | 0.011 | ||
| Eif4e2 | eukaryotic translation initiation factor 4E family member 2 | 0.011 | ||
| Arf6 | ADP-ribosylation factor 6 | 0.011 | ||
| Ly49si1 | immunoreceptor Ly49si1 | 0.011 | Rat | |
| Olr1366 | olfactory receptor 1366 | 0.011 | ||
| Litaf | lipopolysaccharide-induced TNF factor | 0.011 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.011 | ||
| Duoxa1 | dual oxidase maturation factor 1 | 0.011 | ||
| Card6 | caspase recruitment domain family, member 6 | 0.011 | ||
| Capn6 | calpain 6 | 0.010 | ||
| Lrch1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.010 | ||
| Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.010 | ||
| Nfya | nuclear transcription factor-Y alpha | 0.010 | ||
| Cyp2c7 | cytochrome P450, family 2, subfamily c, polypeptide 7 | 0.010 | ||
| Dppa3 | developmental pluripotency-associated 3 | 0.010 | ||
| Hoxa4 | homeo box A4 | 0.010 | ||
| Pla2g2d | phospholipase A2, group IID | 0.010 | ||
| Gen1 | Gen homolog 1, endonuclease (Drosophila) | 0.010 | ||
| Fas | Fas (TNF receptor superfamily, member 6) | 0.010 |