IMP

Process View

Danio rerio

10 genes annotated in zebrafish

axial mesoderm development

The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "axial mesoderm development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "axial mesoderm development" (in gray)

Name	Description	Probability	Func Analog Organism
flh	floating head	0.995
sox10	SRY-box containing gene 10	0.957
ntla	no tail a	0.865	Zebrafish
foxa3	forkhead box A3	0.856
foxi1	forkhead box I1	0.831	Zebrafish
pax2a	paired box gene 2a	0.785
shha	sonic hedgehog a	0.784
eya1	eyes absent homolog 1	0.610
foxa2	forkhead box A2	0.582
myf5	myogenic factor 5	0.546
ndr2	nodal-related 2	0.517
cdh2	cadherin 2, neuronal	0.449
oep	one-eyed pinhead	0.361
notch1a	notch homolog 1a	0.355
tbx2b	T-box 2b	0.353
mib	mind bomb	0.292
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.289
dct	dopachrome tautomerase	0.207
osr2	odd-skipped related 2 (Drosophila)	0.196
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.186
fn1	fibronectin 1	0.172
dlc	deltaC	0.168
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.155
rbfox1l	RNA binding protein, fox-1 homolog (C. elegans) 1-like	0.152
grem2	gremlin 2, cysteine knot superfamily	0.150
foxc1a	forkhead box C1a	0.134
atoh7	atonal homolog 7	0.134
hnf1ba	HNF1 homeobox Ba	0.130
foxa1	forkhead box A1	0.124
neurod	neurogenic differentiation	0.122
rx3	retinal homeobox gene 3	0.106
dld	deltaD	0.100
bmp4	bone morphogenetic protein 4	0.096
cdh5	cadherin 5	0.091
nos1	nitric oxide synthase 1 (neuronal)	0.089
bmp2b	bone morphogenetic protein 2b	0.088
hmx4	H6 family homeobox 4	0.087
vcana	versican a	0.086
cdx4	caudal type homeo box transcription factor 4	0.083
her1	hairy-related 1	0.079
foxh1	forkhead box H1	0.076
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.070
dlx6a	distal-less homeobox gene 6a	0.068
pou5f1	POU domain, class 5, transcription factor 1	0.062
tbx5a	T-box 5a	0.059	Zebrafish
six4b	sine oculis homeobox homolog 4b	0.059
smo	smoothened homolog (Drosophila)	0.056
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.054
wnt11	wingless-type MMTV integration site family, member 11	0.053
six3a	sine oculis homeobox homolog 3a	0.051
pcdh8	protocadherin 8	0.050
meox1	mesenchyme homeobox 1	0.048
tbx16	T-box gene 16	0.047	Zebrafish
myod1	myogenic differentiation 1	0.046
jag1b	jagged 1b	0.046
sox32	SRY-box containing gene 32	0.046
bmper	BMP binding endothelial regulator	0.045
neurod6b	neurogenic differentiation 6b	0.043
tfe3b	transcription factor binding to IGHM enhancer 3b	0.043
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.042
ptch1	patched 1	0.040
six4a	sine oculis homeobox homolog 4a	0.039
sox9a	SRY-box containing gene 9a	0.037
fgf10a	fibroblast growth factor 10a	0.036
spns2	spinster homolog 2 (Drosophila)	0.035
notch3	notch homolog 3	0.035
zgc:153997	zgc:153997	0.034
lhx1a	LIM homeobox 1a	0.034
id:ibd2808	id:ibd2808	0.033
isl2a	islet2a	0.033
gata3	GATA-binding protein 3	0.031
supt6h	suppressor of Ty 6 homolog	0.030
zgc:194131	zgc:194131	0.029
nadl1.1	neural adhesion molecule L1.1	0.028
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.028
edn1	endothelin 1	0.028
nkx2.1b	NK2 homeobox 1b	0.028
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.027
fezf2	FEZ family zinc finger 2	0.027
cldn5a	claudin 5a	0.026
foxd3	forkhead box D3	0.025	Zebrafish
ek1	eph-like kinase 1	0.025
prdm1a	PR domain containing 1a, with ZNF domain	0.024
lhx5	LIM homeobox 5	0.024
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.024
fgf8a	fibroblast growth factor 8 a	0.024
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.023
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.023
fgf3	fibroblast growth factor 3	0.022
nppa	natriuretic peptide precursor A	0.022
dspa	desmoplakin a	0.022
mab21l2	mab-21-like 2	0.022
alx4b	aristaless-like homeobox 4b	0.021
gata5	GATA-binding protein 5	0.021
pkd2	polycystic kidney disease 2	0.021
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.020
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.020
otx2	orthodenticle homolog 2	0.019
fgf19	fibroblast growth factor 19	0.019
gli1	GLI-Kruppel family member 1	0.018
msgn1	mesogenin 1	0.018
otx1b	orthodenticle homolog 1b	0.018
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.017
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.017
col8a1a	collagen, type VIII, alpha 1a	0.017
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.016
nkx2.3	NK2 transcription factor related 3	0.016
vsx1	visual system homeobox 1 homolog, chx10-like	0.016
tmem2	transmembrane protein 2	0.015
myl7	myosin, light polypeptide 7, regulatory	0.015
sufu	suppressor of fused homolog (Drosophila)	0.015
msxc	muscle segment homeobox C	0.015
tcf21	transcription factor 21	0.014
vangl2	vang-like 2 (van gogh, Drosophila)	0.014
wnt5b	wingless-type MMTV integration site family, member 5b	0.014
foxd5	forkhead box D5	0.014
fbln1	fibulin 1	0.014
hoxa11a	homeo box A11a	0.014
dsg2	desmoglein 2	0.014
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.013
pou3f3b	POU class 3 homeobox 3b	0.013
evpl	envoplakin	0.013
slc8a1a	solute carrier family 8 (sodium/calcium exchanger), member 1a	0.013
otx5	orthodenticle homolog 5	0.012
prl	prolactin	0.012
vasa	vasa homolog	0.012
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.012
chd	chordin	0.012
kita	kit receptor a	0.012
flncb	filamin C, gamma b (actin binding protein 280)	0.012
brd2a	bromodomain-containing 2a	0.012
gcm2	glial cells missing homolog 2 (Drosophila)	0.011
tyrp1b	tyrosinase-related protein 1b	0.011
lhx1b	LIM homeobox 1b	0.011
vmhc	ventricular myosin heavy chain	0.011
LOC566708	FL cytokine receptor-like	0.011
pou1f1	POU domain, class 1, transcription factor 1	0.011
im:7137555	im:7137555	0.011
klf2a	Kruppel-like factor 2a	0.011
prkci	protein kinase C, iota	0.011
rx2	retinal homeobox gene 2	0.011
tbx3	T-box 3	0.011	Zebrafish
eomesa	eomesodermin homolog a	0.011	Zebrafish
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.011
notch1b	notch homolog 1b	0.011
lrp2	low density lipoprotein-related protein 2	0.011
emx3	empty spiracles homeobox 3	0.010
chd7	chromodomain helicase DNA binding protein 7	0.010
crb2a	crumbs homolog 2a	0.010
bmp7a	bone morphogenetic protein 7a	0.010
her7	hairy and enhancer of split related-7	0.010
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.010
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.010
otx1a	orthodenticle homolog 1a	0.010
her9	hairy-related 9	0.010