IMP

Process View

Danio rerio

4 genes annotated in zebrafish

canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation" (in gray)

Name	Description	Probability	Func Analog Organism
gata6	GATA-binding protein 6	0.783
met	met proto-oncogene (hepatocyte growth factor receptor)	0.458
hlxb9la	homeo box HB9 like a	0.297	Zebrafish
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.235
frem3	Fras1 related extracellular matrix 3	0.184
irx3a	iroquois homeobox protein 3a	0.178
mnx1	motor neuron and pancreas homeobox 1	0.124	Zebrafish
olig4	oligodendrocyte transcription factor 4	0.119
rarab	retinoic acid receptor, alpha b	0.115
foxa1	forkhead box A1	0.089
meis3	myeloid ecotropic viral integration site 3	0.087
il17rd	interleukin 17 receptor D	0.086
irx4a	iroquois homeobox protein 4a	0.082
nkx2.2a	NK2 transcription factor related 2a	0.081
ntla	no tail a	0.077
foxa2	forkhead box A2	0.076
nkx6.2	NK6 transcription factor related, locus 2	0.075
foxa3	forkhead box A3	0.074
cdx1b	caudal type homeobox 1 b	0.072
sox3	SRY-box containing gene 3	0.070
oep	one-eyed pinhead	0.063
lmo4a	LIM domain only 4a	0.060
flh	floating head	0.058
znf503	zinc finger protein 503	0.055
ctgf	connective tissue growth factor	0.052
pou5f1	POU domain, class 5, transcription factor 1	0.052
wnt11	wingless-type MMTV integration site family, member 11	0.052
pcdh18b	protocadherin 18b	0.051
lef1	lymphocyte enhancer binding factor 1	0.049
irf6	interferon regulatory factor 6	0.048
rnasel1	ribonuclease like 1	0.047
dld	deltaD	0.047
cdx4	caudal type homeo box transcription factor 4	0.046
hlxb9lb	homeo box HB9 like b	0.046	Zebrafish
ins	preproinsulin	0.045
hoxc8a	homeo box C8a	0.044
lhx5	LIM homeobox 5	0.042
olig2	oligodendrocyte lineage transcription factor 2	0.042
shha	sonic hedgehog a	0.039
smad9	MAD homolog 9 (Drosophila)	0.039
irx7	iroquois homeobox protein 7	0.038
hoxb1a	homeo box B1a	0.037
eng2b	engrailed 2b	0.036
hoxa4a	homeo box A4a	0.036
hgfa	hepatocyte growth factor a	0.036
gli2a	GLI-Kruppel family member GLI2a	0.036
hoxb2a	homeo box B2a	0.034
wnt3a	wingless-type MMTV integration site family, member 3A	0.033
bon	bonnie and clyde	0.032
scube2	signal peptide, CUB domain, EGF-like 2	0.031
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.030
gdf6a	growth differentiation factor 6a	0.030
tal2	T-cell acute lymphocytic leukemia 2	0.030
foxb1.2	forkhead box B1.2	0.029
lft1	lefty1	0.029
sst2	somatostatin 2	0.028
pcdh18a	protocadherin 18a	0.028
dab1a	disabled homolog 1a (Drosophila)	0.028
six3a	sine oculis homeobox homolog 3a	0.027
pax4	paired box 4	0.027
chd7	chromodomain helicase DNA binding protein 7	0.026
dscam	Down syndrome cell adhesion molecule	0.026
lfng	lunatic fringe homolog	0.024
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.024
irx1b	iroquois homeobox protein 1, b	0.024
mpped2	metallophosphoesterase domain containing 2	0.024
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.023
epha4a	eph receptor A4a	0.023
prdm14	PR domain containing 14	0.022
hoxa2b	homeo box A2b	0.021
hoxd12a	homeo box D12a	0.021
tbx2a	T-box gene 2a	0.021
lhx1a	LIM homeobox 1a	0.020
hoxd11a	homeo box D11a	0.020
zgc:64114	zgc:64114	0.020
fbn2b	fibrillin 2b	0.018
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.018
tpbgl	trophoblast glycoprotein-like	0.018
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.018
eng2a	engrailed 2a	0.018
esrra	estrogen-related receptor alpha	0.017
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.017
prtga	protogenin homolog a (Gallus gallus)	0.017
dzip1	DAZ interacting protein 1	0.017
gsc	goosecoid	0.017
notch1a	notch homolog 1a	0.017
otpb	orthopedia homolog b	0.017
hfe2	hemochromatosis type 2	0.017
pbx4	pre-B-cell leukemia transcription factor 4	0.017
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.017
wnt8a	wingless-type MMTV integration site family, member 8a	0.016
msxc	muscle segment homeobox C	0.016
cdc25	cell division cycle 25 homolog	0.016
gcga	glucagon a and glucagon a-like	0.016
rfng	radical fringe homolog (Drosophila)	0.016
gata2a	GATA-binding protein 2a	0.016
msxb	muscle segment homeobox B	0.015
sst1.1	somatostatin 1, tandem duplicate 1	0.015
hoxa10b	homeo box A10b	0.015
pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.015
siah1	seven in absentia homolog 1 (Drosophila)	0.015
znf703	zinc finger protein 703	0.015
phc2	polyhomeotic-like 2 (Drosophila)	0.015
crabp2a	cellular retinoic acid binding protein 2, a	0.015
dab1b	disabled homolog 1b (Drosophila)	0.015
zic6	zic family member 6	0.015
fzd8b	frizzled homolog 8b	0.015
dcc	deleted in colorectal carcinoma	0.015
nkx2.5	NK2 transcription factor related 5	0.014
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.014
myl7	myosin, light polypeptide 7, regulatory	0.014
isl2a	islet2a	0.014
acvr2b	activin receptor IIb	0.014
sp5l	Sp5 transcription factor-like	0.014
nort	notch-regulated transcript	0.014
etv5b	ets variant 5b	0.014
mib	mind bomb	0.014
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.013
fev	FEV (ETS oncogene family)	0.013
hoxd13a	homeo box D13a	0.013
has2	hyaluronan synthase 2	0.013
zgc:171495	zgc:171495	0.013
zic4	zic family member 4	0.013
foxd3	forkhead box D3	0.013
auts2	autism susceptibility candidate 2	0.013
fzd8a	frizzled homolog 8a	0.013
vsx2	visual system homeobox 2	0.013
irx5a	iroquois homeobox protein 5a	0.013
sp8a	sp8 transcription factor a	0.013
gata5	GATA-binding protein 5	0.013
wnt9a	wingless-type MMTV integration site family, member 9A	0.012
hoxa13b	homeo box A13b	0.012
nfasca	neurofascin homolog (chicken) a	0.012
rfx6	regulatory factor X, 6	0.012
nkx2.2b	NK2 transcription factor related 2b	0.012
epha7	eph receptor A7	0.012
sox19a	SRY-box containing gene 19a	0.012
pitx2	paired-like homeodomain transcription factor 2	0.012
nkx2.3	NK2 transcription factor related 3	0.012
jag2	jagged 2	0.012
scn12ab	sodium channel, voltage gated, type XII, alpha b	0.011
ext1a	exostoses (multiple) 1a	0.011
nkd1	naked cuticle homolog 1 (Drosophila)	0.011
prickle1b	prickle homolog 1 (Drosophila) b	0.011
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.011
hoxb10a	homeo box B10a	0.011
otx1b	orthodenticle homolog 1b	0.011
cldn7b	claudin 7b	0.011
inka1a	induced in neural crest by AP2, 1a	0.011
hgfb	hepatocyte growth factor b	0.011
serinc5	serine incorporator 5	0.010
si:dkeyp-63d11.7	si:dkeyp-63d11.7	0.010
ctsl1b	cathepsin L, 1 b	0.010
fgfr1b	fibroblast growth factor receptor 1b	0.010
fgf17	fibroblast growth factor 17	0.010
hnf1ba	HNF1 homeobox Ba	0.010
wif1	wnt inhibitory factor 1	0.010
hhex	hematopoietically expressed homeobox	0.010
dbx1a	developing brain homeobox 1a	0.010
hapln1a	hyaluronan and proteoglycan link protein 1a	0.010