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Danio rerio

10 genes annotated in zebrafish

Multi-species View

negative regulation of protein maturation

GO:1903318

Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein maturation" (in gray)

Name	Description	Probability	Func Analog Organism
hhip	hedgehog interacting protein	0.380
col1a1a	collagen, type I, alpha 1a	0.241
ef1a	elongation factor 1-alpha	0.199
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.165
mcl1b	myeloid cell leukemia sequence 1b	0.121
bhmt	betaine-homocysteine methyltransferase	0.116
cdc20	cell division cycle 20 homolog	0.101	Yeast
igf1rb	insulin-like growth factor 1b receptor	0.098
tp53	tumor protein p53	0.073	Mouse
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.061
mcl1a	myeloid cell leukemia sequence 1a	0.058
eng2a	engrailed 2a	0.057
tacc3	transforming, acidic coiled-coil containing protein 3	0.041
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.041
si:ch211-244o22.2	si:ch211-244o22.2	0.040
matn4	matrilin 4	0.039
btg2	B-cell translocation gene 2	0.038
gro2	groucho 2	0.035
shha	sonic hedgehog a	0.035	Mouse Fly
usp5	ubiquitin specific protease 5	0.033
si:ch211-69g19.2	si:ch211-69g19.2	0.032
ptch1	patched 1	0.031
ptf1a	pancreas specific transcription factor, 1a	0.030
ambpl	alpha-1-microglobulin/bikunin precursor, like	0.029	Rat
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.028
zgc:56200	zgc:56200	0.027
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.027
nkx2.2a	NK2 transcription factor related 2a	0.025
csf1ra	colony stimulating factor 1 receptor, a	0.025
itih2	inter-alpha (globulin) inhibitor H2	0.024
a1cf	apobec1 complementation factor	0.024
adipor2	adiponectin receptor 2	0.024
pax5	paired box gene 5	0.022
nr5a1b	nuclear receptor subfamily 5, group A, member 1b	0.022
hgfb	hepatocyte growth factor b	0.022
spi1l	spleen focus forming virus (SFFV) proviral integration oncogene spi1 like	0.021
c9	complement component 9	0.020
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.020
axin1	axin 1	0.020
pou3f2	POU class 3 homeobox 2	0.019
serpina1l	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like	0.018
bactin2	bactin2	0.018
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.018
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.018
ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.018
kif11	kinesin family member 11	0.018
sox9b	SRY-box containing gene 9b	0.018
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.018
plg	plasminogen	0.018
cdca8	cell division cycle associated 8	0.017
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.017
zgc:101723	zgc:101723	0.017
spon1b	spondin 1b	0.017
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.017
baxa	bcl2-associated X protein, a	0.017	Zebrafish
pklr	pyruvate kinase, liver and RBC	0.017
gbx2	gastrulation brain homeo box 2	0.017
nf1a	neurofibromin 1a	0.016
LOC100006043	Kruppel-like factor 5-like	0.016
bbc3	BCL2 binding component 3	0.016
caprin1a	cell cycle associated protein 1a	0.016
aurkb	aurora kinase B	0.016
bag6	BCL2-associated athanogene 6	0.016
rtkn2	rhotekin 2	0.015
LOC564872	monocarboxylate transporter 7-like	0.015
otud5a	OTU domain containing 5a	0.015
sod1	superoxide dismutase 1, soluble	0.015
nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.015
bad	BCL2-antagonist of cell death	0.015
boka	BCL2-related ovarian killer a	0.015	Zebrafish
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.015
plcg1	phospholipase C, gamma 1	0.014
pitx3	paired-like homeodomain transcription factor 3	0.014
cdt1	chromatin licensing and DNA replication factor 1	0.014
zgc:123326	zgc:123326	0.014
si:dkey-202c5.1	si:dkey-202c5.1	0.014
wnt8b	wingless-type MMTV integration site family, member 8b	0.014
faf2	Fas associated factor family member 2	0.014
fga	fibrinogen alpha chain	0.014
sulf2l	sulfatase 2, like	0.013
il8	interleukin 8	0.013
hsp70	heat shock cognate 70-kd protein	0.013
ctsba	cathepsin B, a	0.012
wu:fj39b01	wu:fj39b01	0.012
LOC566708	FL cytokine receptor-like	0.012
LOC100536090	targeting protein for Xklp2-B-like	0.012
LOC100330224	fatty acid binding protein 1b-like	0.012
melk	maternal embryonic leucine zipper kinase	0.012
mab21l1	mab-21-like 1	0.012
nusap1	nucleolar and spindle associated protein 1	0.012
f2	coagulation factor II (thrombin)	0.012	Human
pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.012
calcrla	calcitonin receptor-like a	0.012
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.011
zgc:172246	zgc:172246	0.011
ripk2	receptor-interacting serine-threonine kinase 2	0.011
fzd5	frizzled homolog 5	0.011
zgc:73345	zgc:73345	0.011
tbpl2	TATA box binding protein like 2	0.011
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.011
fetub	fetuin B	0.011
kif23	kinesin family member 23	0.011
foxe3	forkhead box E3	0.011
zgc:85727	zgc:85727	0.011
adcyap1r1a	adenylate cyclase activating polypeptide 1 receptor 1a	0.010
sgpl1	sphingosine-1-phosphate lyase 1	0.010
aplp2	amyloid beta (A4) precursor-like protein 2	0.010
flh	floating head	0.010
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.010