IMP

Process View

Danio rerio

20 genes annotated in zebrafish

regulation of cellular response to stress

Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cellular response to stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cellular response to stress" (in gray)

Name	Description	Probability	Func Analog Organism
notch3	notch homolog 3	0.078
chd	chordin	0.077
flh	floating head	0.075
foxa3	forkhead box A3	0.074	Worm
dkk1b	dickkopf 1b	0.068
cdh1	cadherin 1, epithelial	0.052
bcl2l1	bcl2-like 1	0.046	Human
fn1	fibronectin 1	0.041	Zebrafish
ctsl1a	cathepsin L, 1 a	0.039
ppm1aa	protein phosphatase, Mg2+/Mn2+ dependent, 1Aa	0.038	Fly
fzd7a	frizzled homolog 7a	0.038
il6r	interleukin 6 receptor	0.037
stc1l	stanniocalcin 1, like	0.036
epha4a	eph receptor A4a	0.036
odc1	ornithine decarboxylase 1	0.034
baxa	bcl2-associated X protein, a	0.033	Human
cry3	cryptochrome 3	0.030
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.029
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.028
gsc	goosecoid	0.028
pias4a	protein inhibitor of activated STAT, 4a	0.027	Mouse
arf2	ADP-ribosylation factor 2	0.027
mapk3	mitogen-activated protein kinase 3	0.026	Fly
sox19a	SRY-box containing gene 19a	0.026
prpf4b	PRP4 pre-mRNA processing factor 4 homolog B	0.026
notch2	notch homolog 2	0.025
per3	period homolog 3 (Drosophila)	0.024
igf1ra	insulin-like growth factor 1a receptor	0.024	Human Worm
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.024	Mouse
tlr3	toll-like receptor 3	0.024	Mouse
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.023
ripk2	receptor-interacting serine-threonine kinase 2	0.023
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.023
arl4ab	ADP-ribosylation factor-like 4ab	0.023
nod1	nucleotide-binding oligomerization domain containing 1	0.023
ncor1	nuclear receptor co-repressor 1	0.022	Human
tbx6	T-box gene 6	0.022
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.022
ephb4a	eph receptor B4a	0.022	Zebrafish
bmp2b	bone morphogenetic protein 2b	0.022	Human
smad5	MAD homolog 5 (Drosophila)	0.021
cmyb	transcription factor cmyb	0.021
atf3	activating transcription factor 3	0.021
mcl1a	myeloid cell leukemia sequence 1a	0.021	Human Mouse
ptena	phosphatase and tensin homolog A	0.021	Fly
trim13	tripartite motif-containing 13	0.021
fgf3	fibroblast growth factor 3	0.021
zbtb4	zinc finger and BTB domain containing 4	0.021
igf1	insulin-like growth factor 1	0.021
osr1	odd-skipped related 1 (Drosophila)	0.020
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.020	Human Mouse
hspa4a	heat shock protein 4a	0.020
znf703	zinc finger protein 703	0.020
jag2	jagged 2	0.020
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.019	Mouse
esco2	establishment of cohesion 1 homolog 2	0.019
nrg2a	neuregulin 2a	0.019
dhfr	dihydrofolate reductase	0.019
wnt5a	wingless-type MMTV integration site family, member 5a	0.019
elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.019
bbc3	BCL2 binding component 3	0.019
eng1a	engrailed 1a	0.019
hbbe3	hemoglobin beta embryonic-3	0.019	Mouse
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.019	Human
sf3b1	splicing factor 3b, subunit 1	0.018
ctbp2l	C-terminal binding protein 2, like	0.018
furinb	furin (paired basic amino acid cleaving enzyme) b	0.018
dbx1a	developing brain homeobox 1a	0.018
hmga1a	high mobility group AT-hook 1a	0.017	Human
furina	furin (paired basic amino acid cleaving enzyme) a	0.017
tm9sf2	transmembrane 9 superfamily member 2	0.017
tp53bp2	tumor protein p53 binding protein, 2	0.017
ctsl1b	cathepsin L, 1 b	0.017
sod1	superoxide dismutase 1, soluble	0.017	Human
ifnphi1	interferon phi 1	0.017
igf1rb	insulin-like growth factor 1b receptor	0.016	Human Worm
ved	ventrally expressed dharma/bozozok antagonist	0.016
ran	ras-related nuclear protein	0.016
frzb	frizzled-related protein	0.016	Rat
spry2	sprouty homolog 2	0.016
crip2	cysteine-rich protein 2	0.015
nkx6.2	NK6 transcription factor related, locus 2	0.015
eif4e	eukaryotic translation initiation factor 4e	0.015
gro1	groucho 1	0.015
ntn2	netrin 2	0.015
cand1	cullin-associated and neddylation-dissociated 1	0.015
mapk14a	mitogen-activated protein kinase 14a	0.015
gstp1	glutathione S-transferase pi	0.015	Human Mouse
rbb4	retinoblastoma binding protein 4	0.015
her1	hairy-related 1	0.015
card9	caspase recruitment domain family, member 9	0.015	Mouse
mmp9	matrix metalloproteinase 9	0.015
rpsa	ribosomal protein SA	0.015
seh1l	SEH1-like (S. cerevisiae)	0.014
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.014
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014
ccng1	cyclin G1	0.014
dab1a	disabled homolog 1a (Drosophila)	0.014
gro2	groucho 2	0.014
tipin	timeless interacting protein	0.014
mvp	major vault protein	0.014
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.014
scn1a	sodium channel, voltage-gated, type I, alpha	0.014
si:dkey-18f23.10	si:dkey-18f23.10	0.014
zgc:55558	zgc:55558	0.014	Fly
rpa1	replication protein A1	0.014
srsf6b	serine/arginine-rich splicing factor 6b	0.014
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.014
pdx1	pancreatic and duodenal homeobox 1	0.014	Mouse
rhoub	ras homolog gene family, member Ub	0.013
dag1	dystroglycan 1	0.013
zgc:101026	zgc:101026	0.013
sfrp1b	secreted frizzled-related protein 1b	0.013	Mouse
ndr1	nodal-related 1	0.013
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.013
fzd5	frizzled homolog 5	0.013	Mouse
zgc:64114	zgc:64114	0.013
LOC557072	caspase recruitment domain-containing protein 11-like	0.013
sart3	squamous cell carcinoma antigen recognised by T cells 3	0.013
lpp	LIM domain containing preferred translocation partner in lipoma	0.013
ptk2.1	protein tyrosine kinase 2a	0.013
acvr1b	activin A receptor, type IB	0.013
rbb4l	retinoblastoma binding protein 4, like	0.013
slc25a37	solute carrier family 25, member 37	0.013
angpt1	angiopoietin 1	0.013
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.013
eya2	eyes absent homolog 2 (Drosophila)	0.013
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.013
kirrel3l	kin of IRRE like 3 like	0.013
adra2b	adrenergic, alpha-2B-, receptor	0.013	Worm
wnt4a	wingless-type MMTV integration site family, member 4a	0.013
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.013
mcl1b	myeloid cell leukemia sequence 1b	0.012	Human Mouse
insm1a	insulinoma-associated 1a	0.012
eaf2	ELL associated factor 2	0.012
crabp2b	cellular retinoic acid binding protein 2, b	0.012
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.012
mpx	myeloid-specific peroxidase	0.012
setd5	SET domain containing 5	0.012
pspc1	paraspeckle component 1	0.012	Zebrafish
irf9	interferon regulatory factor 9	0.012
msh2	mutS homolog 2 (E. coli)	0.012
lamc1	laminin, gamma 1	0.012
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.012
gadd45g	growth arrest and DNA-damage-inducible, gamma	0.012	Human
wnt5b	wingless-type MMTV integration site family, member 5b	0.012	Human Mouse
ldb1a	LIM-domain binding factor 1a	0.012
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.012
ass1	argininosuccinate synthetase 1	0.012
angptl2	angiopoietin-like 2	0.012
ckap5	cytoskeleton associated protein 5	0.012
kbp	kif1-binding protein	0.011
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.011
zc3h13	zinc finger CCCH-type containing 13	0.011
lfng	lunatic fringe homolog	0.011
epor	erythropoietin receptor	0.011
rhoab	ras homolog gene family, member Ab	0.011
traf4a	tnf receptor-associated factor 4a	0.011	Fly
pitpnb	phosphotidylinositol transfer protein, beta	0.011
gbx1	gastrulation brain homeobox 1	0.011
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.011
LOC556764	similar to Probable RNA-dependent helicase p72 (DEAD-box protein p72) (DEAD-box protein 17)	0.011
fgfr1b	fibroblast growth factor receptor 1b	0.011
btk	Bruton agammaglobulinemia tyrosine kinase	0.011
bms1l	BMS1-like, ribosome assembly protein (yeast)	0.011
wnt8b	wingless-type MMTV integration site family, member 8b	0.011
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.011
bida	BH3 interacting domain death agonist	0.011
brd4	bromodomain containing 4	0.011
ggnbp2	gametogenetin binding protein 2	0.011
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.011	Human
msi1	musashi homolog 1 (Drosophila)	0.011
srsf1b	serine/arginine-rich splicing factor 1b	0.011
rpl3	ribosomal protein L3	0.011
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.011
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.011
adh5	alcohol dehydrogenase 5	0.011
dld	deltaD	0.011
arid4a	AT rich interactive domain 4A (RBP1-like)	0.011
fgfr3	fibroblast growth factor receptor 3	0.011
jun	jun proto-oncogene	0.011
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.010
sox4b	SRY-box containing gene 4b	0.010
zgc:153997	zgc:153997	0.010
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.010
fbxo11-like	F-box only protein 11-like	0.010
foxc1b	forkhead box C1b	0.010
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.010
ptgesl	prostaglandin E synthase 2-like	0.010
hirip3	HIRA interacting protein 3	0.010
ptf1a	pancreas specific transcription factor, 1a	0.010
si:ch211-57k11.10	si:ch211-57k11.10	0.010
per2	period homolog 2 (Drosophila)	0.010
tlk1b	tousled-like kinase 1b	0.010
rplp2	ribosomal protein, large P2	0.010
LOC563527	brain-specific angiogenesis inhibitor 1-like	0.010
foxd3	forkhead box D3	0.010
myd88	myeloid differentiation primary response gene (88)	0.010	Mouse
arf6	ADP-ribosylation factor 6	0.010
gata3	GATA-binding protein 3	0.010
phf16	PHD finger protein 16	0.010
dedd1	death effector domain-containing 1	0.010
foxi3b	forkhead box I3b	0.010
rangap1	Ran GTPase activating protein 1	0.010