IMP
Process View
The network for 'regulation of mitochondrial membrane permeability involved in apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of mitochondrial membrane permeability involved in apoptotic process
Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BCL2 | B-cell CLL/lymphoma 2 | 0.999 | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.997 | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.995 | |
| BAK1 | BCL2-antagonist/killer 1 | 0.973 | |
| BAX | BCL2-associated X protein | 0.960 | |
| BCL2L1 | BCL2-like 1 | 0.901 | |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.874 | |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.871 | |
| BID | BH3 interacting domain death agonist | 0.834 | |
| BECN1 | beclin 1, autophagy related | 0.667 | |
| BAD | BCL2-associated agonist of cell death | 0.619 | |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.607 | |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.535 | |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.394 | |
| VDAC1 | voltage-dependent anion channel 1 | 0.366 | |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.265 | |
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 0.264 | |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.253 | |
| BBC3 | BCL2 binding component 3 | 0.249 | |
| FKBP8 | FK506 binding protein 8, 38kDa | 0.242 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.210 | |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.189 | |
| JUN | jun proto-oncogene | 0.164 | |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.158 | |
| PGK1 | phosphoglycerate kinase 1 | 0.135 | |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.121 | |
| AXIN1 | axin 1 | 0.093 | |
| VDAC2 | voltage-dependent anion channel 2 | 0.086 | |
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.080 | |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.078 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.078 | |
| ZHX1 | zinc fingers and homeoboxes 1 | 0.075 | |
| OCIAD1 | OCIA domain containing 1 | 0.070 | |
| IER2 | immediate early response 2 | 0.067 | |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.066 | |
| ATP5A1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 0.062 | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.062 | |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 0.056 | |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.055 | |
| ATF3 | activating transcription factor 3 | 0.054 | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.052 | |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 0.049 | |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.046 | |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.046 | |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 0.043 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.042 | |
| RNF144B | ring finger protein 144B | 0.042 | |
| HDAC6 | histone deacetylase 6 | 0.040 | |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.039 | |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 0.038 | |
| TMEM11 | transmembrane protein 11 | 0.034 | |
| FH | fumarate hydratase | 0.034 | |
| ATP5G3 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) | 0.034 | |
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.033 | |
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.032 | |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.031 | |
| MAGEH1 | melanoma antigen family H, 1 | 0.030 | |
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.030 | |
| LDHA | lactate dehydrogenase A | 0.029 | |
| CDK10 | cyclin-dependent kinase 10 | 0.028 | |
| RHOA | ras homolog gene family, member A | 0.028 | |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 0.027 | |
| MS4A7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.027 | |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.026 | |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | 0.026 | |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.023 | |
| QARS | glutaminyl-tRNA synthetase | 0.023 | |
| SIX1 | SIX homeobox 1 | 0.023 | |
| DLG4 | discs, large homolog 4 (Drosophila) | 0.022 | |
| YPEL5 | yippee-like 5 (Drosophila) | 0.021 | |
| GHITM | growth hormone inducible transmembrane protein | 0.020 | |
| EGR1 | early growth response 1 | 0.019 | |
| RNR2 | l-rRNA | 0.019 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.019 | |
| ELK1 | ELK1, member of ETS oncogene family | 0.018 | |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.018 | |
| SNAPIN | SNAP-associated protein | 0.018 | |
| GLRX5 | glutaredoxin 5 | 0.017 | |
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.017 | |
| TKT | transketolase | 0.017 | |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.017 | |
| SNX3 | sorting nexin 3 | 0.017 | |
| HMOX2 | heme oxygenase (decycling) 2 | 0.016 | |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.016 | |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 0.016 | |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.016 | |
| GRIA4 | glutamate receptor, ionotrophic, AMPA 4 | 0.016 | |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.016 | |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 0.015 | |
| CNO | cappuccino homolog (mouse) | 0.015 | |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.015 | |
| HDAC4 | histone deacetylase 4 | 0.015 | |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 0.015 | |
| ZFYVE1 | zinc finger, FYVE domain containing 1 | 0.015 | |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.015 | |
| PRNP | prion protein | 0.015 | |
| JUNB | jun B proto-oncogene | 0.014 | |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.014 | |
| POLH | polymerase (DNA directed), eta | 0.014 | |
| UVRAG | UV radiation resistance associated gene | 0.014 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Bax | BCL2-associated X protein | 0.999 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.987 | |
| Trp53 | transformation related protein 53 | 0.963 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.814 | |
| Pten | phosphatase and tensin homolog | 0.773 | |
| Mcl1 | myeloid cell leukemia sequence 1 | 0.628 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.499 | |
| Kit | kit oncogene | 0.457 | |
| Bak1 | BCL2-antagonist/killer 1 | 0.230 | |
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.229 | |
| Sharpin | SHANK-associated RH domain interacting protein | 0.199 | |
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.185 | |
| Apc | adenomatosis polyposis coli | 0.173 | |
| Pdcd6ip | programmed cell death 6 interacting protein | 0.157 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.137 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.116 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.079 | |
| Mapk8 | mitogen-activated protein kinase 8 | 0.072 | |
| Trp73 | transformation related protein 73 | 0.072 | |
| Rara | retinoic acid receptor, alpha | 0.064 | |
| Dnm1 | dynamin 1 | 0.062 | |
| Mta1 | metastasis associated 1 | 0.056 | |
| Mtap2 | microtubule-associated protein 2 | 0.053 | |
| Tbx1 | T-box 1 | 0.052 | |
| Lyst | lysosomal trafficking regulator | 0.050 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.049 | |
| Atxn2 | ataxin 2 | 0.048 | |
| Gipc1 | GIPC PDZ domain containing family, member 1 | 0.046 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.043 | |
| Braf | Braf transforming gene | 0.041 | |
| Actn2 | actinin alpha 2 | 0.040 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.039 | |
| Acd | adrenocortical dysplasia | 0.039 | |
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.037 | |
| Btbd2 | BTB (POZ) domain containing 2 | 0.036 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.030 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.028 | |
| Skil | SKI-like | 0.027 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.026 | |
| Igh | immunoglobulin heavy chain complex | 0.026 | |
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.025 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.025 | |
| Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 0.025 | |
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.024 | |
| Six2 | sine oculis-related homeobox 2 homolog (Drosophila) | 0.023 | |
| Acadm | acyl-Coenzyme A dehydrogenase, medium chain | 0.022 | |
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.022 | |
| Mapk1 | mitogen-activated protein kinase 1 | 0.022 | |
| Bhlhe40 | basic helix-loop-helix family, member e40 | 0.022 | |
| Bid | BH3 interacting domain death agonist | 0.022 | |
| Bcl2l1 | BCL2-like 1 | 0.021 | |
| Sox2 | SRY-box containing gene 2 | 0.021 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.021 | |
| Rbck1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.021 | |
| Arc | activity regulated cytoskeletal-associated protein | 0.021 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.020 | |
| Etfa | electron transferring flavoprotein, alpha polypeptide | 0.020 | |
| Dlx2 | distal-less homeobox 2 | 0.020 | |
| Trpc2 | transient receptor potential cation channel, subfamily C, member 2 | 0.020 | |
| Klf6 | Kruppel-like factor 6 | 0.019 | |
| Bmf | BCL2 modifying factor | 0.019 | |
| Foxp3 | forkhead box P3 | 0.019 | |
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.018 | |
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.017 | |
| Rb1 | retinoblastoma 1 | 0.017 | |
| Mapk9 | mitogen-activated protein kinase 9 | 0.017 | |
| Mfn2 | mitofusin 2 | 0.016 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.016 | |
| 2700094K13Rik | RIKEN cDNA 2700094K13 gene | 0.015 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.015 | |
| Rarb | retinoic acid receptor, beta | 0.015 | |
| Ep300 | E1A binding protein p300 | 0.015 | |
| Pax6 | paired box gene 6 | 0.014 | |
| Ccnd1 | cyclin D1 | 0.014 | |
| Etfdh | electron transferring flavoprotein, dehydrogenase | 0.013 | |
| Casp3 | caspase 3 | 0.013 | |
| Retsat | retinol saturase (all trans retinol 13,14 reductase) | 0.013 | |
| Fbxw7 | F-box and WD-40 domain protein 7 | 0.012 | |
| Nampt | nicotinamide phosphoribosyltransferase | 0.012 | |
| Gnb2 | guanine nucleotide binding protein (G protein), beta 2 | 0.011 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.011 | |
| Pgk1 | phosphoglycerate kinase 1 | 0.011 | |
| Pmm1 | phosphomannomutase 1 | 0.011 | |
| Galk1 | galactokinase 1 | 0.011 | |
| Kitl | kit ligand | 0.011 | |
| Rps27l | ribosomal protein S27-like | 0.011 | |
| Id1 | inhibitor of DNA binding 1 | 0.011 | |
| Gmnn | geminin | 0.011 | |
| Park2 | Parkinson disease (autosomal recessive, juvenile) 2, parkin | 0.010 | |
| Gstz1 | glutathione transferase zeta 1 (maleylacetoacetate isomerase) | 0.010 | |
| Snrpg | small nuclear ribonucleoprotein polypeptide G | 0.010 | |
| Rxra | retinoid X receptor alpha | 0.010 | |
| Drap1 | Dr1 associated protein 1 (negative cofactor 2 alpha) | 0.010 | |
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.010 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.010 | |
| Hr | hairless | 0.010 |