The network for 'embryonic hindlimb morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic hindlimb morphogenesis

The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.

Homo sapiens
Name Description Probability Func Analog Organism
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.982
BTRC beta-transducin repeat containing 0.838
PBRM1 polybromo 1 0.679
JAG1 jagged 1 0.623
ELL2 elongation factor, RNA polymerase II, 2 0.576
CHD8 chromodomain helicase DNA binding protein 8 0.405
AFF1 AF4/FMR2 family, member 1 0.396
SETD8 SET domain containing (lysine methyltransferase) 8 0.339
GSK3B glycogen synthase kinase 3 beta 0.318
ARID1A AT rich interactive domain 1A (SWI-like) 0.271
APC adenomatous polyposis coli 0.268
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.263
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.206
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.196
ZFYVE9 zinc finger, FYVE domain containing 9 0.192
CCNT1 cyclin T1 0.170
TCF4 transcription factor 4 0.165
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.165
FGF18 fibroblast growth factor 18 0.160
NOTCH3 notch 3 0.156
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.155
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.134
MSX2 msh homeobox 2 0.132
WNT1 wingless-type MMTV integration site family, member 1 0.129
LRRK2 leucine-rich repeat kinase 2 0.122
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.121
GCSH glycine cleavage system protein H (aminomethyl carrier) 0.119
MSX1 msh homeobox 1 0.113
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.105
ARID1B AT rich interactive domain 1B (SWI1-like) 0.101
AXIN1 axin 1 0.100
XIAP X-linked inhibitor of apoptosis 0.096
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.092
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.087
JUP junction plakoglobin 0.087
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.086
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.070
PSEN1 presenilin 1 0.066
WNT3A wingless-type MMTV integration site family, member 3A 0.063
PGAM5 phosphoglycerate mutase family member 5 0.061
FGF3 fibroblast growth factor 3 0.057
FOXF2 forkhead box F2 0.057
MED26 mediator complex subunit 26 0.056
MMP11 matrix metallopeptidase 11 (stromelysin 3) 0.056
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.055
FGF8 fibroblast growth factor 8 (androgen-induced) 0.055
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.054
GLIS2 GLIS family zinc finger 2 0.053
WNT11 wingless-type MMTV integration site family, member 11 0.052
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.052
HIC1 hypermethylated in cancer 1 0.051
TARBP2 TAR (HIV-1) RNA binding protein 2 0.051
CTNND1 catenin (cadherin-associated protein), delta 1 0.049
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.048
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.048
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.046
DLX5 distal-less homeobox 5 0.046
HOXC8 homeobox C8 0.045
MAML1 mastermind-like 1 (Drosophila) 0.043
GATA2 GATA binding protein 2 0.043
AQP5 aquaporin 5 0.043
BHLHE23 basic helix-loop-helix family, member e23 0.042
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.042
JAG2 jagged 2 0.040
LBX1 ladybird homeobox 1 0.040
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.040
TBX2 T-box 2 0.039
FBLN1 fibulin 1 0.038
WNT3 wingless-type MMTV integration site family, member 3 0.038
NKX3-2 NK3 homeobox 2 0.037
PAX3 paired box 3 0.037
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.036
SORBS3 sorbin and SH3 domain containing 3 0.036
WNT10A wingless-type MMTV integration site family, member 10A 0.036
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.036
ACAN aggrecan 0.035
SHH sonic hedgehog 0.035
WNT4 wingless-type MMTV integration site family, member 4 0.035
WIF1 WNT inhibitory factor 1 0.034
SFRP1 secreted frizzled-related protein 1 0.034
PML promyelocytic leukemia 0.034
RBBP5 retinoblastoma binding protein 5 0.034
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.032
BMP4 bone morphogenetic protein 4 0.032
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.031
LEF1 lymphoid enhancer-binding factor 1 0.031
MYOD1 myogenic differentiation 1 0.031
CDX1 caudal type homeobox 1 0.031
PTGIS prostaglandin I2 (prostacyclin) synthase 0.031
TP53BP1 tumor protein p53 binding protein 1 0.031
HES2 hairy and enhancer of split 2 (Drosophila) 0.031
CRABP2 cellular retinoic acid binding protein 2 0.031
COL2A1 collagen, type II, alpha 1 0.031
PRRX2 paired related homeobox 2 0.030
RADIL Ras association and DIL domains 0.030
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.030
PKP4 plakophilin 4 0.030
RBM11 RNA binding motif protein 11 0.030
EAF1 ELL associated factor 1 0.029
TLX3 T-cell leukemia homeobox 3 0.029
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 0.977
Pitx1 paired-like homeodomain transcription factor 1 0.969
Pax8 paired box gene 8 0.949
Msx1 homeobox, msh-like 1 0.947
Fgfr2 fibroblast growth factor receptor 2 0.945
Pax2 paired box gene 2 0.932
Hand1 heart and neural crest derivatives expressed transcript 1 0.925
Pitx2 paired-like homeodomain transcription factor 2 0.920
Tbx3 T-box 3 0.909
Fgf8 fibroblast growth factor 8 0.908
Alx4 aristaless-like homeobox 4 0.896
Rarg retinoic acid receptor, gamma 0.887
Hoxa1 homeobox A1 0.872
Dlx5 distal-less homeobox 5 0.849
Otx2 orthodenticle homolog 2 (Drosophila) 0.843
Pax3 paired box gene 3 0.831
Nodal nodal 0.828
Fgf10 fibroblast growth factor 10 0.820
Gli2 GLI-Kruppel family member GLI2 0.820
Tbx1 T-box 1 0.805
T brachyury 0.794
Smo smoothened homolog (Drosophila) 0.791
Rara retinoic acid receptor, alpha 0.786
Pax9 paired box gene 9 0.781
Runx2 runt related transcription factor 2 0.774
Wnt3a wingless-related MMTV integration site 3A 0.769
Fgfr1 fibroblast growth factor receptor 1 0.767
Chrd chordin 0.726
En1 engrailed 1 0.707
Chd7 chromodomain helicase DNA binding protein 7 0.678
Foxc2 forkhead box C2 0.668
Lhx1 LIM homeobox protein 1 0.665
Hand2 heart and neural crest derivatives expressed transcript 2 0.660
Bmp4 bone morphogenetic protein 4 0.636
Hoxa11 homeobox A11 0.632
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.601
Gbx2 gastrulation brain homeobox 2 0.579
Hoxd11 homeobox D11 0.577
Sox9 SRY-box containing gene 9 0.551
Prrx1 paired related homeobox 1 0.529
Rarb retinoic acid receptor, beta 0.527
Hoxa13 homeobox A13 0.519
Pten phosphatase and tensin homolog 0.473
Notch1 Notch gene homolog 1 (Drosophila) 0.461
Tbx15 T-box 15 0.454
Zic3 zinc finger protein of the cerebellum 3 0.452
Sox2 SRY-box containing gene 2 0.450
Hoxa10 homeobox A10 0.442
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.439
Gata4 GATA binding protein 4 0.439
Neurog2 neurogenin 2 0.408
Sox11 SRY-box containing gene 11 0.403
Rxra retinoid X receptor alpha 0.400
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.400
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.375
Tcf15 transcription factor 15 0.344
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.344
Eya1 eyes absent 1 homolog (Drosophila) 0.339
Amhr2 anti-Mullerian hormone type 2 receptor 0.318
Wt1 Wilms tumor 1 homolog 0.308
Twist2 twist homolog 2 (Drosophila) 0.305
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.305
Prrx2 paired related homeobox 2 0.299
Vangl2 vang-like 2 (van gogh, Drosophila) 0.288
Hmx3 H6 homeobox 3 0.278
Bmp7 bone morphogenetic protein 7 0.273
Tgfb2 transforming growth factor, beta 2 0.258
Ar androgen receptor 0.246
Gsc goosecoid homeobox 0.229
Wnt5a wingless-related MMTV integration site 5A 0.225
Gata3 GATA binding protein 3 0.221
Jag1 jagged 1 0.215
Alx3 aristaless-like homeobox 3 0.214
Foxc1 forkhead box C1 0.206
Hoxd13 homeobox D13 0.196
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.174
Apc adenomatosis polyposis coli 0.172
Lrp6 low density lipoprotein receptor-related protein 6 0.172
Notch2 Notch gene homolog 2 (Drosophila) 0.169
Neurog1 neurogenin 1 0.158
Ptf1a pancreas specific transcription factor, 1a 0.152
Hoxa2 homeobox A2 0.151
Sall4 sal-like 4 (Drosophila) 0.147
Zeb1 zinc finger E-box binding homeobox 1 0.146
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.145
App amyloid beta (A4) precursor protein 0.144
Tbx4 T-box 4 0.143
Pou4f3 POU domain, class 4, transcription factor 3 0.140
Ctnnb1 catenin (cadherin associated protein), beta 1 0.140
Dll1 delta-like 1 (Drosophila) 0.134
Lmx1a LIM homeobox transcription factor 1 alpha 0.130
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.129
Dlx2 distal-less homeobox 2 0.128
Fgf18 fibroblast growth factor 18 0.126
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.122
Nhlh1 nescient helix loop helix 1 0.122
Tbx5 T-box 5 0.119
Efna2 ephrin A2 0.118
Shox2 short stature homeobox 2 0.118
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Rattus norvegicus
Name Description Probability Func Analog Organism
Mmp13 matrix metallopeptidase 13 0.228
Hrasls5 HRAS-like suppressor family, member 5 0.184
Mmp3 matrix metallopeptidase 3 0.158
Mmp7 matrix metallopeptidase 7 0.136
Il6 interleukin 6 0.127
Tacr1 tachykinin receptor 1 0.104
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.074
Lepr leptin receptor 0.073
Plau plasminogen activator, urokinase 0.069
Ereg epiregulin 0.064
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.062
Chd4 chromodomain helicase DNA binding protein 4 0.054
Msx1 msh homeobox 1 0.053
Lef1 lymphoid enhancer binding factor 1 0.051
Gabrr1 gamma-aminobutyric acid (GABA) receptor, rho 1 0.049
Prkch protein kinase C, eta 0.047
Pip prolactin induced protein 0.044
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.042
Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 0.041
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.040
Accn3 amiloride-sensitive cation channel 3 0.038
Gtf2i general transcription factor II I 0.038
Mmp9 matrix metallopeptidase 9 0.037
Ccl4 chemokine (C-C motif) ligand 4 0.036
Mybph myosin binding protein H 0.036
Sf3b2 splicing factor 3b, subunit 2 0.036
Ibsp integrin-binding sialoprotein 0.036
Cma1 chymase 1, mast cell 0.035
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.035
Mcpt2 mast cell protease 2 0.035
Serpinb12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 0.034
Calcb calcitonin-related polypeptide, beta 0.034
Egr2 early growth response 2 0.034
Mprip myosin phosphatase Rho interacting protein 0.034
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.033
Fblim1 filamin binding LIM protein 1 0.032
LOC290595 hypothetical gene supported by AF152002 0.032
Ccl11 chemokine (C-C motif) ligand 11 0.032
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.032
Aspg asparaginase homolog (S. cerevisiae) 0.031
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.030
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.029
Arhgap10 Rho GTPase activating protein 10 0.027
Gcm1 glial cells missing homolog 1 (Drosophila) 0.027
Ascl2 achaete-scute complex homolog 2 (Drosophila) 0.027
Eln elastin 0.027
Clec9a C-type lectin domain family 9, member a 0.027
Il1a interleukin 1 alpha 0.027
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.026
Ctrc chymotrypsin C (caldecrin) 0.026
Mmp12 matrix metallopeptidase 12 0.026
Tcfe2a transcription factor E2a 0.025
Gja5 gap junction protein, alpha 5 0.025
Nkd1 naked cuticle homolog 1 (Drosophila) 0.025
Ubtf upstream binding transcription factor, RNA polymerase I 0.024
Agtr1b angiotensin II receptor, type 1b 0.024
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.024
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.024
Tfec transcription factor EC 0.024
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.023
Psgb1 pregnancy-specific beta 1-glycoprotein 0.023
Bst1 bone marrow stromal cell antigen 1 0.023
Sfrp4 secreted frizzled-related protein 4 0.022
Cxcl2 chemokine (C-X-C motif) ligand 2 0.022
Mrgprf MAS-related GPR, member F 0.022
Ccna1 cyclin A1 0.022
Expi extracellular proteinase inhibitor 0.022
Ccr1 chemokine (C-C motif) receptor 1 0.021
Neurl3 neuralized homolog 3 (Drosophila) 0.021
Sc65 synaptonemal complex protein SC65 0.021
Wnt5a wingless-type MMTV integration site family, member 5A 0.021
P22k15 cystatin related protein 2 0.021
Dock6 dedicator of cytokinesis 6 0.021
Phex phosphate regulating endopeptidase homolog, X-linked 0.020
Prl3a1 Prolactin family 3, subfamily a, member 1 0.020
Insl6 insulin-like 6 0.020
Sprr3 small proline-rich protein 3 0.019
Col12a1 collagen, type XII, alpha 1 0.019
Crisp1 cysteine-rich secretory protein 1 0.019
Pbsn probasin 0.019
Mca32 mast cell antigen 32 0.019
Col5a1 collagen, type V, alpha 1 0.019
Cd80 Cd80 molecule 0.018
Trex2 three prime repair exonuclease 2 0.018
Myod1 myogenic differentiation 1 0.018
Lce1f late cornified envelope 1F 0.018
LOC683313 similar to keratin complex 2, basic, gene 6a 0.018
Chia chitinase, acidic 0.018
LOC304558 similar to TPR repeat-containing protein KIAA1043 0.017
Klra5 killer cell lectin-like receptor, subfamily A, member 5 0.017
Fgf15 fibroblast growth factor 15 0.017
Kazald1 Kazal-type serine peptidase inhibitor domain 1 0.017
Ptges prostaglandin E synthase 0.017
Selp selectin P 0.017
Gna15 guanine nucleotide binding protein, alpha 15 0.017
Cpxm2 carboxypeptidase X (M14 family), member 2 0.017
LOC207127 similar to preprotein translocase 0.017
Vom1r93 vomeronasal 1 receptor 93 0.017
Cela1 chymotrypsin-like elastase family, member 1 0.016
Svs4 seminal vesicle secretory protein 4 0.016
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism