The network for 'steroid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

Mus musculus
Name Description Probability Func Analog Organism
Pax8 paired box gene 8 0.972
Ghr growth hormone receptor 0.916
Kl klotho 0.898
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.697
Cyp51 cytochrome P450, family 51 0.686
Prlr prolactin receptor 0.684
Pax2 paired box gene 2 0.609
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.607
Otc ornithine transcarbamylase 0.571
Ar androgen receptor 0.537
Sox9 SRY-box containing gene 9 0.501
Grb10 growth factor receptor bound protein 10 0.484
Lss lanosterol synthase 0.475
Mvd mevalonate (diphospho) decarboxylase 0.444
Apoe apolipoprotein E 0.398
Dhcr24 24-dehydrocholesterol reductase 0.364
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.357
Ldlr low density lipoprotein receptor 0.354
Esr1 estrogen receptor 1 (alpha) 0.349
Rxra retinoid X receptor alpha 0.347
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.346
Apob apolipoprotein B 0.335
Cps1 carbamoyl-phosphate synthetase 1 0.334
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.334
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.317
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.306
Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.289
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.280
Dhcr7 7-dehydrocholesterol reductase 0.269
Rarg retinoic acid receptor, gamma 0.268
Amhr2 anti-Mullerian hormone type 2 receptor 0.264
Sqle squalene epoxidase 0.253
Duox2 dual oxidase 2 0.252
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.246
Fgfr1 fibroblast growth factor receptor 1 0.240
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.234
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.234
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.227
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.221
Insr insulin receptor 0.210
Dmgdh dimethylglycine dehydrogenase precursor 0.208
Thrb thyroid hormone receptor beta 0.207
Foxc1 forkhead box C1 0.206
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.205
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.199
G6pc glucose-6-phosphatase, catalytic 0.195
Bmp7 bone morphogenetic protein 7 0.187
Shh sonic hedgehog 0.184
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.184
Keg1 kidney expressed gene 1 0.180
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.173
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.169
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 0.169
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.165
Lepr leptin receptor 0.156
Pik3c2g phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide 0.152
Slc12a1 solute carrier family 12, member 1 0.151
Il1a interleukin 1 alpha 0.151
Azgp1 alpha-2-glycoprotein 1, zinc 0.148
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.147
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.147
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.145
Gata4 GATA binding protein 4 0.144
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.139
Fasn fatty acid synthase 0.137
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.136
Ihh Indian hedgehog 0.133
Rarb retinoic acid receptor, beta 0.132
Wnt4 wingless-related MMTV integration site 4 0.130
Afm afamin 0.130
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.128
Bmp4 bone morphogenetic protein 4 0.128
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.128
Nsdhl NAD(P) dependent steroid dehydrogenase-like 0.124
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 0.124
Prrx2 paired related homeobox 2 0.120
Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5 0.118
Sult1b1 sulfotransferase family 1B, member 1 0.116
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.114
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.114
Tgfb1 transforming growth factor, beta 1 0.111
Sc4mol sterol-C4-methyl oxidase-like 0.110
Idi1 isopentenyl-diphosphate delta isomerase 0.108
Cdhr5 cadherin-related family member 5 0.104
Pparg peroxisome proliferator activated receptor gamma 0.104
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.103
Timp1 tissue inhibitor of metalloproteinase 1 0.101
0610007P14Rik RIKEN cDNA 0610007P14 gene 0.099
Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 0.098
Ces1g carboxylesterase 1G 0.098
Fgfr2 fibroblast growth factor receptor 2 0.097
Fgfr3 fibroblast growth factor receptor 3 0.097
Dct dopachrome tautomerase 0.096
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 0.094
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.094
Wnt9b wingless-type MMTV integration site 9B 0.093
Rara retinoic acid receptor, alpha 0.092
Lhx1 LIM homeobox protein 1 0.091
Hgd homogentisate 1, 2-dioxygenase 0.091
Kcnk4 potassium channel, subfamily K, member 4 0.090
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
bar-1 Protein BAR-1 0.034
bli-1 Protein BLI-1 0.020
dpy-8 Protein DPY-8 0.016
CELE_ZK1025.3 Protein ZK1025.3 0.016
CELE_Y11D7A.5 Protein Y11D7A.5 0.013
CELE_E01G4.6 Protein E01G4.6 0.013
CELE_C29F7.2 Protein C29F7.2 0.013
col-128 Protein COL-128 0.013
ethe-1 Protein ETHE-1 0.013
CELE_Y46G5A.29 Protein Y46G5A.29 0.013
pry-1 Protein PRY-1 0.013
oac-30 Protein OAC-30 0.012
col-79 Protein COL-79 0.012
pdfr-1 Protein PDFR-1 0.012
col-38 Protein COL-38 0.011
grd-1 Protein GRD-1 0.011
ZK1127.6 Protein ZK1127.6 0.011
pap-1 Protein PAP-1 0.011
egl-23 Protein EGL-23 0.010
clh-1 Protein CLH-1 0.010
cdh-7 Protein CDH-7 0.010
plc-3 Protein PLC-3 0.010
bah-1 Protein BAH-1 0.010
Y71H2AM.13 Protein Y71H2AM.13 0.010
clec-180 Protein CLEC-180 0.010
col-110 Protein COL-110 0.010
dhs-20 Protein DHS-20 0.010
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Danio rerio
Name Description Probability Func Analog Organism
apoa4 apolipoprotein A-IV 0.244
cldn1 claudin 1 0.137
lhcgr luteinizing hormone/choriogonadotropin receptor 0.136
ocrl oculocerebrorenal syndrome of Lowe 0.135
cyp1a cytochrome P450, family 1, subfamily A 0.118
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.105
inha inhibin, alpha 0.092
nanos3 nanos homolog 3 0.082
plcg1 phospholipase C, gamma 1 0.078
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.074
cldn2 claudin 2 0.070
paqr8 progestin and adipoQ receptor family member VIII 0.059
ins preproinsulin 0.053
igf3 insulin-like growth factor 3 0.051
mt2 metallothionein 2 0.051
apoa1 apolipoprotein A-I 0.051
bmp4 bone morphogenetic protein 4 0.050
star steroidogenic acute regulatory protein 0.050
pla2g12b phospholipase A2, group XIIB 0.044
hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.041
slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.040
nipblb novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila) 0.037
inhbab inhibin, beta Ab 0.035
casrl calcium-sensing receptor, like 0.033
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.031
bactin2 bactin2 0.031
myl7 myosin, light polypeptide 7, regulatory 0.030
epas1a endothelial PAS domain protein 1a 0.030
apobl apolipoprotein B, like 0.029
tm4sf4 transmembrane 4 L six family member 4 0.029
hsd17b12b hydroxysteroid (17-beta) dehydrogenase 12b 0.028
mtp microsomal triglyceride transfer protein 0.026
shbg sex hormone binding globulin 0.026
cldnc claudin c 0.025
grifin galectin related inter-fiber protein 0.024
gdf6a growth differentiation factor 6a 0.023
atp1a1a.3 ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide 0.023
hsd17b12a hydroxysteroid (17-beta) dehydrogenase 12a 0.022
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.022
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.022
grn2 granulin 2 0.021
ihhb Indian hedgehog homolog b 0.020
fgfrl1b fibroblast growth factor receptor-like 1b 0.020
fads2 fatty acid desaturase 2 0.020
grn1 granulin 1 0.019
zgc:161979 zgc:161979 0.018
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.018
wt1b wilms tumor 1b 0.017
ntla no tail a 0.016
ptgs1 prostaglandin-endoperoxide synthase 1 0.016
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.015
ucp3 uncoupling protein 3 0.015
oclnb occludin b 0.014
acvr1l activin A receptor, type I like 0.014
pvalb8 parvalbumin 8 0.014
bmp7a bone morphogenetic protein 7a 0.014
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.014
henmt1 HEN1 methyltransferase homolog 1 (Arabidopsis) 0.014
ihha Indian hedgehog homolog a 0.013
hnf4a hepatocyte nuclear factor 4, alpha 0.013
cyp2p6 cytochrome P450, family 2, subfamily P, polypeptide 6 0.013
zgc:112986 zgc:112986 0.013
hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.013
sox9a SRY-box containing gene 9a 0.013
slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 0.013
pgr progesterone receptor 0.013
lama5 laminin, alpha 5 0.013
mmp9 matrix metalloproteinase 9 0.012
cryaa crystallin, alpha A 0.012
slc8a1b solute carrier family 8 (sodium/calcium exchanger), member 1b 0.012
tbp TATA box binding protein 0.012
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.012
fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 0.012
kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.011
kitb kit receptor b 0.011
rag1 recombination activating gene 1 0.011
sepp1b selenoprotein P, plasma, 1b 0.011
erf Ets2 repressor factor 0.011
crhbp corticotropin releasing hormone binding protein 0.010
sc4mol sterol-C4-methyl oxidase-like 0.010
tgfb1a transforming growth factor, beta 1a 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
dib disembodied 0.900
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.839
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.732
Ugt35a UDP-glycosyltransferase 35a 0.676
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.561
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.556
Npc1a Niemann-Pick type C-1a 0.416
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.284
sad shadow 0.277
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.222
Cyp4e2 Cytochrome P450-4e2 0.207
Rpb4 CG33520 gene product from transcript CG33520-RF 0.195
CG6834 CG6834 gene product from transcript CG6834-RA 0.168
Snoo Sno oncogene 0.162
CG5973 CG5973 gene product from transcript CG5973-RA 0.147
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.146
Cyp9b2 Cytochrome P450-9b2 0.145
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.140
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.130
pex13 peroxin 13 0.130
Hr4 CG16902 gene product from transcript CG16902-RC 0.129
Hph HIF prolyl hydroxylase 0.119
nvd neverland 0.103
Cyp6a9 Cytochrome P450-6a9 0.101
Cyp6g1 CG8453 gene product from transcript CG8453-RA 0.095
sro shroud 0.090
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.087
CG31122 CG31122 gene product from transcript CG31122-RA 0.087
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.086
Phm Peptidylglycine-alpha-hydroxylating monooxygenase 0.085
Src42A Src oncogene at 42A 0.083
CG2233 CG2233 gene product from transcript CG2233-RA 0.077
sim single-minded 0.073
Pros35 Proteasome 35kD subunit 0.071
CG6830 CG6830 gene product from transcript CG6830-RA 0.071
CG9319 CG9319 gene product from transcript CG9319-RA 0.068
gcm glial cells missing 0.065
Kr Kruppel 0.064
Acox57D-p acyl-Coenzyme A oxidase at 57D proximal 0.063
Cyp4p1 Cytochrome P450-4p1 0.061
CG5326 CG5326 gene product from transcript CG5326-RA 0.061
CG15828 CG15828 gene product from transcript CG15828-RC 0.058
rols rolling pebbles 0.053
spo spook 0.052
spok spookier 0.049
Mes2 CG11100 gene product from transcript CG11100-RB 0.047
Fer1HCH Ferritin 1 heavy chain homologue 0.047
CG1516 CG1516 gene product from transcript CG1516-RP 0.047
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.045
Fatp Fatty acid (long chain) transport protein 0.044
TotA Turandot A 0.041
CG6908 CG6908 gene product from transcript CG6908-RA 0.041
ush u-shaped 0.040
CG1927 CG1927 gene product from transcript CG1927-RA 0.039
CG9360 CG9360 gene product from transcript CG9360-RA 0.039
zen zerknullt 0.038
ttm50 tiny tim 50 0.038
alpha-Est7 alpha-Esterase-7 0.037
shd shade 0.037
Aldh-III Aldehyde dehydrogenase type III 0.036
Invadolysin CG3953 gene product from transcript CG3953-RA 0.035
Epac CG34392 gene product from transcript CG34392-RC 0.033
Cyp9h1 CG17577 gene product from transcript CG17577-RA 0.033
CG33120 CG33120 gene product from transcript CG33120-RA 0.032
eve even skipped 0.032
CG31937 CG31937 gene product from transcript CG31937-RA 0.032
Eip63E Ecdysone-induced protein 63E 0.032
Cyp6a8 Cytochrome P450-6a8 0.032
Trf2 TATA box binding protein-related factor 2 0.031
Est-Q Esterase Q 0.030
CG10550 CG10550 gene product from transcript CG10550-RB 0.030
Plc21C Phospholipase C at 21C 0.029
myoglianin CG1838 gene product from transcript CG1838-RD 0.029
CG15609 CG15609 gene product from transcript CG15609-RE 0.029
hkb huckebein 0.028
CG10562 CG10562 gene product from transcript CG10562-RA 0.028
CG12672 CG12672 gene product from transcript CG12672-RA 0.028
CG6028 CG6028 gene product from transcript CG6028-RA 0.028
sec23 CG1250 gene product from transcript CG1250-RA 0.028
mbl muscleblind 0.027
MED4 Mediator complex subunit 4 0.027
CG7997 CG7997 gene product from transcript CG7997-RB 0.027
CG5162 CG5162 gene product from transcript CG5162-RA 0.027
CG7530 CG7530 gene product from transcript CG7530-RB 0.025
Npc1b Niemann-Pick type C-1b 0.025
alpha-Est2 alpha-Esterase-2 0.024
tsg twisted gastrulation 0.024
Hsc70-3 Heat shock protein cognate 3 0.024
nrv1 nervana 1 0.023
CG5819 CG5819 gene product from transcript CG5819-RA 0.023
wnd wallenda 0.023
CG16936 CG16936 gene product from transcript CG16936-RA 0.023
srp serpent 0.023
Jheh3 Juvenile hormone epoxide hydrolase 3 0.023
CG3415 CG3415 gene product from transcript CG3415-RA 0.023
bnl branchless 0.023
CG13526 CG13526 gene product from transcript CG13526-RA 0.023
Obp99c Odorant-binding protein 99c 0.023
CG7470 CG7470 gene product from transcript CG7470-RA 0.023
lab labial 0.022
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
DHCR7 7-dehydrocholesterol reductase 1.000
FGFR2 fibroblast growth factor receptor 2 1.000
HNF4A hepatocyte nuclear factor 4, alpha 0.999
SREBF2 sterol regulatory element binding transcription factor 2 0.999
FGF1 fibroblast growth factor 1 (acidic) 0.998
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.989
FDPS farnesyl diphosphate synthase 0.982
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.982
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.960
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.960
SQLE squalene epoxidase 0.945
FGFR1 fibroblast growth factor receptor 1 0.910
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.901
DHCR24 24-dehydrocholesterol reductase 0.895
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.893
IL1R1 interleukin 1 receptor, type I 0.887
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.859
C14orf1 chromosome 14 open reading frame 1 0.805
BMPR1A bone morphogenetic protein receptor, type IA 0.790
CREBBP CREB binding protein 0.774
GH1 growth hormone 1 0.760
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.712
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.702
ZFYVE9 zinc finger, FYVE domain containing 9 0.697
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.686
INSIG1 insulin induced gene 1 0.630
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.628
SC4MOL sterol-C4-methyl oxidase-like 0.617
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.554
ESR1 estrogen receptor 1 0.553
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.550
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.541
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.530
ACAT2 acetyl-CoA acetyltransferase 2 0.510
RORA RAR-related orphan receptor A 0.487
FADS1 fatty acid desaturase 1 0.476
IDI1 isopentenyl-diphosphate delta isomerase 1 0.473
MVD mevalonate (diphospho) decarboxylase 0.471
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.449
NCOR2 nuclear receptor corepressor 2 0.445
BCL3 B-cell CLL/lymphoma 3 0.442
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.428
GH2 growth hormone 2 0.399
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.391
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.339
ESRRG estrogen-related receptor gamma 0.339
LDLR low density lipoprotein receptor 0.331
CSHL1 chorionic somatomammotropin hormone-like 1 0.313
TNIP1 TNFAIP3 interacting protein 1 0.311
HSPB1 heat shock 27kDa protein 1 0.299
EBP emopamil binding protein (sterol isomerase) 0.287
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.268
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.213
HP haptoglobin 0.211
FGF8 fibroblast growth factor 8 (androgen-induced) 0.196
PGRMC1 progesterone receptor membrane component 1 0.190
MED15 mediator complex subunit 15 0.182
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.178
ITGB1BP3 integrin beta 1 binding protein 3 0.178
ACLY ATP citrate lyase 0.167
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.166
SMAD3 SMAD family member 3 0.159
APOC1 apolipoprotein C-I 0.158
FASN fatty acid synthase 0.152
INSR insulin receptor 0.150
EP300 E1A binding protein p300 0.148
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.145
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.144
SMN1 survival of motor neuron 1, telomeric 0.139
IL1RAP interleukin 1 receptor accessory protein 0.139
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.137
FGF4 fibroblast growth factor 4 0.133
TNIP2 TNFAIP3 interacting protein 2 0.130
BMPR1B bone morphogenetic protein receptor, type IB 0.129
RXRA retinoid X receptor, alpha 0.128
MYO6 myosin VI 0.122
APOC3 apolipoprotein C-III 0.115
FGF10 fibroblast growth factor 10 0.115
HIPK2 homeodomain interacting protein kinase 2 0.115
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.114
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.108
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.107
WNT1 wingless-type MMTV integration site family, member 1 0.105
IL1B interleukin 1, beta 0.104
APOC2 apolipoprotein C-II 0.099
NOG noggin 0.097
ACAA2 acetyl-CoA acyltransferase 2 0.092
FGF2 fibroblast growth factor 2 (basic) 0.090
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.089
ALB albumin 0.088
POU5F1 POU class 5 homeobox 1 0.084
IGF2R insulin-like growth factor 2 receptor 0.083
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.081
HR hairless homolog (mouse) 0.081
APOA2 apolipoprotein A-II 0.080
PROX1 prospero homeobox 1 0.078
FADS2 fatty acid desaturase 2 0.077
ACACA acetyl-CoA carboxylase alpha 0.076
NCOA1 nuclear receptor coactivator 1 0.075
FOXD3 forkhead box D3 0.075
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp51 cytochrome P450, family 51 0.961
Sc4mol sterol-C4-methyl oxidase-like 0.961
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.945
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.855
Insig1 insulin induced gene 1 0.769
Sqle squalene epoxidase 0.729
Idi1 isopentenyl-diphosphate delta isomerase 1 0.663
Pip prolactin induced protein 0.507
Sult1c3 sulfotransferase family, cytosolic, 1C, member 3 0.477
Fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 0.438
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 0.406
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.371
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.347
Fasn fatty acid synthase 0.317
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.303
LOC293989 cytochrome P450-like 0.290
Dhcr7 7-dehydrocholesterol reductase 0.277
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.252
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.248
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.244
Dbp D site of albumin promoter (albumin D-box) binding protein 0.243
Clca4 chloride channel accessory 4 0.210
Dhcr24 24-dehydrocholesterol reductase 0.192
Ghr growth hormone receptor 0.186
Prb1 proline-rich protein BstNI subfamily 1 0.186
Sc5dl sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like 0.174
Cuzd1 CUB and zona pellucida-like domains 1 0.173
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.162
Pth parathyroid hormone 0.162
Xcl1 chemokine (C motif) ligand 1 0.146
Sv2c synaptic vesicle glycoprotein 2c 0.144
Klk1c10 T-kininogenase 0.132
Tm7sf2 transmembrane 7 superfamily member 2 0.132
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.128
Agxt alanine-glyoxylate aminotransferase 0.122
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.113
Krt34 keratin 34 0.112
Kcne1 potassium voltage-gated channel, Isk-related family, member 1 0.110
Rdh7 retinol dehydrogenase 7 0.110
Prl7d1 prolactin family 7, subfamily d, member 1 0.108
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.102
Vom1r93 vomeronasal 1 receptor 93 0.097
Lactb2 lactamase, beta 2 0.095
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.090
Bdkrb1 bradykinin receptor B1 0.090
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.089
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 0.088
Obp1f odorant binding protein I f 0.087
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.085
Mcpt3 mast cell peptidase 3 0.085
Hcrtr2 hypocretin (orexin) receptor 2 0.082
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.082
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.081
Ptgfr prostaglandin F receptor 0.080
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.080
Mettl7b methyltransferase like 7B 0.079
Olr1361 olfactory receptor 1361 0.079
Mrgprx3 MAS-related GPR, member X3 0.078
Agtr1b angiotensin II receptor, type 1b 0.075
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.075
Fam108b1 family with sequence similarity 108, member B1 0.075
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.075
Nsdhl NAD(P) dependent steroid dehydrogenase-like 0.073
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.072
Tcf21 transcription factor 21 0.071
Nrg1 neuregulin 1 0.071
Cyb5a cytochrome b5 type A (microsomal) 0.069
Aqp9 aquaporin 9 0.069
Clph casein-like phosphoprotein 0.068
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.067
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.067
Atp6v1g3 ATPase, H+ transporting, lysosomal V1 subunit G3 0.067
Vcsa2 variable coding sequence A2 0.066
P2ry1 purinergic receptor P2Y, G-protein coupled, 1 0.066
Apob apolipoprotein B 0.065
Cyct cytochrome c, testis 0.065
Tas2r118 taste receptor, type 2, member 118 0.065
Tg thyroglobulin 0.063
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.062
Art2 ADP-ribosyltransferase 2 0.062
Hal histidine ammonia lyase 0.061
Rln1 relaxin 1 0.061
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.060
Prl prolactin 0.060
Lepr leptin receptor 0.060
Ivl involucrin 0.059
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.059
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.057
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.057
Hrasls5 HRAS-like suppressor family, member 5 0.057
Pnlip pancreatic lipase 0.057
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.056
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.054
Gnrh1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.053
Klkb1 kallikrein B, plasma 1 0.053
Dnase1 deoxyribonuclease I 0.051
Sgp158 proline-rich glycoprotein (sgp158) 0.051
Npffr2 neuropeptide FF receptor 2 0.050
Shc3 SHC (Src homology 2 domain containing) transforming protein 3 0.050
Olr1654 olfactory receptor 1654 0.050
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ERG25 Erg25p 0.999
ERG3 Erg3p 0.997
ERG26 Erg26p 0.996
ERG27 Erg27p 0.995
ERG5 Erg5p 0.993
ERG28 Erg28p 0.993
ERG7 Erg7p 0.991
ERG11 Erg11p 0.988
ERG2 Erg2p 0.963
ERG6 Erg6p 0.892
ERG24 Erg24p 0.848
ERG8 Erg8p 0.790
HMG1 Hmg1p 0.785
ERG13 Erg13p 0.760
ERG9 Erg9p 0.717
MVD1 Mvd1p 0.668
ERG4 Erg4p 0.643
ERG1 Erg1p 0.569
ERG10 Erg10p 0.482
ERG12 Erg12p 0.353
BUL2 Bul2p 0.286
ECM22 Ecm22p 0.191
YJU3 Yju3p 0.185
SCM4 Scm4p 0.172
MIG2 Mig2p 0.170
PHO86 Pho86p 0.160
CSR2 Csr2p 0.149
YKR075C hypothetical protein 0.115
YEH1 Yeh1p 0.097
ZAP1 Zap1p 0.085
SAM2 Sam2p 0.082
SLC1 Slc1p 0.081
UPC2 Upc2p 0.078
HAP1 Hap1p 0.077
HXT3 Hxt3p 0.075
TRA1 Tra1p 0.071
MIG3 Mig3p 0.071
YPL014W hypothetical protein 0.069
CYB5 Cyb5p 0.065
EHT1 Eht1p 0.060
HMG2 Hmg2p 0.060
NUP157 Nup157p 0.058
CSI1 Csi1p 0.056
ARE2 Are2p 0.056
CYC7 Cyc7p 0.055
MET4 Met4p 0.052
ATF2 Atf2p 0.051
CSN9 Csn9p 0.050
ROX1 Rox1p 0.049
RGS2 Rgs2p 0.046
LYS5 Lys5p 0.045
STF1 Stf1p 0.044
MSC7 Msc7p 0.044
HAL5 Hal5p 0.043
EAF3 Eaf3p 0.042
PSD2 Psd2p 0.041
MIG1 Mig1p 0.040
HSP42 Hsp42p 0.040
MOT3 Mot3p 0.039
LEU1 Leu1p 0.036
ACS2 Acs2p 0.035
VID24 Vid24p 0.034
AGP1 Agp1p 0.033
MBR1 Mbr1p 0.033
SIM1 Sim1p 0.032
TGL1 Tgl1p 0.032
SUR1 Sur1p 0.029
HHO1 Hho1p 0.029
DLD1 Dld1p 0.029
HXK2 Hxk2p 0.028
RIM101 Rim101p 0.027
DAL81 Dal81p 0.027
YIR035C hypothetical protein 0.027
ARG80 Arg80p 0.026
FMT1 Fmt1p 0.026
YMR102C hypothetical protein 0.026
MET30 Met30p 0.026
MGA2 Mga2p 0.026
BSD2 Bsd2p 0.026
YDR307W hypothetical protein 0.026
SWI1 Swi1p 0.026
YKL187C hypothetical protein 0.025
GAT2 Gat2p 0.025
ICY1 Icy1p 0.025
SEF1 Sef1p 0.025
YSR3 Ysr3p 0.025
FUN19 Fun19p 0.024
GLG1 Glg1p 0.024
ADI1 Adi1p 0.024
PGM1 Pgm1p 0.024
YPK2 Ypk2p 0.024
LAC1 Lac1p 0.024
RAD28 Rad28p 0.024
YHR045W hypothetical protein 0.023
TYE7 Tye7p 0.023
SEC21 Sec21p 0.023
OPY2 Opy2p 0.023
OLE1 Ole1p 0.023
PET10 Pet10p 0.023
UFO1 Ufo1p 0.023