The network for 'motor neuron axon guidance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

motor neuron axon guidance

The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.

Mus musculus
Name Description Probability Func Analog Organism
Gli3 GLI-Kruppel family member GLI3 1.000
Jag1 jagged 1 0.999
Efnb2 ephrin B2 0.995
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.993
Vangl2 vang-like 2 (van gogh, Drosophila) 0.988
Otx2 orthodenticle homolog 2 (Drosophila) 0.987
Pax2 paired box gene 2 0.985
Epha4 Eph receptor A4 0.971
Fgfr2 fibroblast growth factor receptor 2 0.962
Hoxa1 homeobox A1 0.961
Gli2 GLI-Kruppel family member GLI2 0.954
Fgfr1 fibroblast growth factor receptor 1 0.945
Isl1 ISL1 transcription factor, LIM/homeodomain 0.936
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.935
Ntf3 neurotrophin 3 0.933
Ctnnb1 catenin (cadherin associated protein), beta 1 0.932
Slit2 slit homolog 2 (Drosophila) 0.925
Lhx1 LIM homeobox protein 1 0.921
Ptk7 PTK7 protein tyrosine kinase 7 0.906
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.894
Robo1 roundabout homolog 1 (Drosophila) 0.885
Sox2 SRY-box containing gene 2 0.882
Pitx2 paired-like homeodomain transcription factor 2 0.869
Shh sonic hedgehog 0.848
Emx1 empty spiracles homolog 1 (Drosophila) 0.845
Eya1 eyes absent 1 homolog (Drosophila) 0.838
Gdnf glial cell line derived neurotrophic factor 0.832
Fgf8 fibroblast growth factor 8 0.824
Emx2 empty spiracles homolog 2 (Drosophila) 0.816
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.802
En1 engrailed 1 0.801
Fyn Fyn proto-oncogene 0.789
Chd7 chromodomain helicase DNA binding protein 7 0.772
Dcc deleted in colorectal carcinoma 0.766
Ikzf1 IKAROS family zinc finger 1 0.753
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.752
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.712
Rarg retinoic acid receptor, gamma 0.694
Ldb2 LIM domain binding 2 0.689
Ednra endothelin receptor type A 0.681
Tbx1 T-box 1 0.668
Unc5c unc-5 homolog C (C. elegans) 0.650
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.632
Phox2b paired-like homeobox 2b 0.627
Fgf10 fibroblast growth factor 10 0.623
Tgfb2 transforming growth factor, beta 2 0.622
Apc adenomatosis polyposis coli 0.619
Ephb2 Eph receptor B2 0.618
Pbx1 pre B-cell leukemia transcription factor 1 0.606
Nrg1 neuregulin 1 0.598
Bdnf brain derived neurotrophic factor 0.597
Ret ret proto-oncogene 0.592
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.584
Pax3 paired box gene 3 0.578
Pou3f1 POU domain, class 3, transcription factor 1 0.565
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.547
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.547
Zic2 zinc finger protein of the cerebellum 2 0.546
Hoxa2 homeobox A2 0.534
Tbx3 T-box 3 0.522
Pou3f3 POU domain, class 3, transcription factor 3 0.511
Foxc1 forkhead box C1 0.503
Whrn whirlin 0.501
Cachd1 cache domain containing 1 0.497
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.492
Fzd2 frizzled homolog 2 (Drosophila) 0.489
Zfpm2 zinc finger protein, multitype 2 0.486
Enah enabled homolog (Drosophila) 0.484
Slit3 slit homolog 3 (Drosophila) 0.476
Nrp1 neuropilin 1 0.472
Foxg1 forkhead box G1 0.457
Ddr2 discoidin domain receptor family, member 2 0.441
Hes5 hairy and enhancer of split 5 (Drosophila) 0.439
Fbn2 fibrillin 2 0.431
Gbx2 gastrulation brain homeobox 2 0.429
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.415
Lmx1a LIM homeobox transcription factor 1 alpha 0.405
Sdc3 syndecan 3 0.403
Pax6 paired box gene 6 0.398
Hes1 hairy and enhancer of split 1 (Drosophila) 0.398
Bcl2 B-cell leukemia/lymphoma 2 0.396
Notch1 Notch gene homolog 1 (Drosophila) 0.393
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.388
Sox11 SRY-box containing gene 11 0.380
Psen1 presenilin 1 0.364
Foxd2 forkhead box D2 0.349
Meis2 Meis homeobox 2 0.349
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.342
Sall3 sal-like 3 (Drosophila) 0.328
Lef1 lymphoid enhancer binding factor 1 0.322
Plxna1 plexin A1 0.321
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.319
Gpr27 G protein-coupled receptor 27 0.313
Mmp16 matrix metallopeptidase 16 0.313
Lmx1b LIM homeobox transcription factor 1 beta 0.304
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.303
Robo2 roundabout homolog 2 (Drosophila) 0.298
Otx1 orthodenticle homolog 1 (Drosophila) 0.292
Foxc2 forkhead box C2 0.290
Hoxb3 homeobox B3 0.289
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
cam-1 Protein CAM-1 0.894
unc-9 Protein UNC-9 0.787
sdn-1 Protein SDN-1 0.780
mig-2 Protein MIG-2 0.763
elt-6 Protein ELT-6 0.762
pha-4 Protein PHA-4 0.684
R90.1 Protein R90.1 0.625
syg-1 Protein SYG-1 0.600
fmi-1 Protein FMI-1 0.596
sax-3 Protein SAX-3 0.571
cdh-3 Protein CDH-3 0.495
nhr-67 Protein NHR-67 0.441
unc-73 Protein UNC-73 0.437
goa-1 Protein GOA-1 0.406
let-60 Protein LET-60 0.364
igcm-3 Protein IGCM-3 0.343
vab-1 Protein VAB-1 0.325
rig-6 Protein RIG-6 0.310
etr-1 Protein ETR-1 0.304
ncam-1 Protein NCAM-1 0.284
ten-1 Protein TEN-1 0.274
egl-18 Protein EGL-18 0.253
T24B8.3 Protein T24B8.3 0.218
egl-46 Protein EGL-46 0.206
flt-1 Protein FLT-1 0.203
lam-2 Protein LAM-2 0.180
egl-27 Protein EGL-27 0.167
unc-41 Protein UNC-41 0.159
K09F5.6 Protein K09F5.6 0.157
pqn-62 Protein PQN-62 0.156
gap-2 Protein GAP-2 0.152
trim-9 Protein TRIM-9 0.150
mec-2 Protein MEC-2 0.146
hlh-2 Protein HLH-2 0.141
pkn-1 Protein PKN-1 0.131
tag-241 Protein TAG-241 0.129
sel-2 Protein SEL-2 0.121
ced-10 Protein CED-10 0.109
lin-12 Protein LIN-12 0.100
hmg-1.2 Protein HMG-1.2 0.092
ceh-32 Protein CEH-32 0.089
sox-2 Protein SOX-2 0.088
nhr-49 Protein NHR-49 0.088
uso-1 Protein USO-1 0.085
lrp-2 Protein LRP-2 0.085
daf-3 Protein DAF-3 0.083
hbl-1 Protein HBL-1 0.082
ina-1 Protein INA-1 0.081
smp-1 Protein SMP-1 0.081
egl-5 Protein EGL-5 0.080
R10E12.2 Protein R10E12.2 0.080
frm-3 Protein FRM-3 0.078
elc-1 Protein ELC-1 0.075
dgn-1 Protein DGN-1 0.075
lag-2 Protein LAG-2 0.074
sdz-28 Protein SDZ-28 0.071
mab-5 Protein MAB-5 0.069
cdc-42 Protein CDC-42 0.068
sel-8 Protein SEL-8 0.066
lev-8 Protein LEV-8 0.066
cwn-2 Protein CWN-2 0.064
T02E9.5 Protein T02E9.5 0.063
unc-6 Protein UNC-6 0.060
sax-7 Protein SAX-7 0.060
ceh-20 Protein CEH-20 0.057
gmeb-1 Protein GMEB-1 0.052
ptp-3 Protein PTP-3 0.051
F58H1.5 Protein F58H1.5 0.048
F28B3.1 Protein F28B3.1 0.048
pmp-3 Protein PMP-3 0.047
ugt-57 Protein UGT-57 0.047
lsy-2 Protein LSY-2 0.045
lin-17 Protein LIN-17 0.044
unc-129 Protein UNC-129 0.044
chd-3 Protein CHD-3 0.042
gba-3 Protein GBA-3 0.042
F28E10.1 Protein F28E10.1 0.042
F25F8.1 Protein F25F8.1 0.041
ast-1 Protein AST-1 0.041
chd-7 Protein CHD-7 0.039
T23F11.1 Protein T23F11.1 0.038
scd-1 Protein SCD-1 0.038
unc-62 Protein UNC-62 0.037
insc-1 Protein INSC-1 0.037
pat-3 Protein PAT-3 0.036
zfp-1 Protein ZFP-1 0.035
R12C12.7 Protein R12C12.7 0.035
tag-146 Protein TAG-146 0.033
abcf-2 Protein ABCF-2 0.032
eat-16 Protein EAT-16 0.031
C13B9.3 Protein C13B9.3 0.031
C34F6.10 Protein C34F6.10 0.031
plx-2 Protein PLX-2 0.031
egl-30 Protein EGL-30 0.030
unc-42 Protein UNC-42 0.030
efn-2 Protein EFN-2 0.029
nphp-4 Protein NPHP-4 0.029
pop-1 Protein POP-1 0.029
dma-1 Protein DMA-1 0.028
acr-8 Protein ACR-8 0.028
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Danio rerio
Name Description Probability Func Analog Organism
shha sonic hedgehog a 0.992
dla deltaA 0.975
nkx2.2a NK2 transcription factor related 2a 0.972
robo2 roundabout homolog 2 0.920
nrp1a neuropilin 1a 0.913
dag1 dystroglycan 1 0.905
lama2 laminin, alpha 2 0.905
dlb deltaB 0.894
neurog1 neurogenin 1 0.870
lamb2 laminin, beta 2 (laminin S) 0.857
tbx1 T-box 1 0.856
boc brother of CDO 0.836
alcama activated leukocyte cell adhesion molecule a 0.834
gli2a GLI-Kruppel family member GLI2a 0.828
dld deltaD 0.781
nkx3.2 NK3 homeobox 2 0.771
pax2a paired box gene 2a 0.747
sulf1 sulfatase 1 0.730
myf5 myogenic factor 5 0.722
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.715
myod1 myogenic differentiation 1 0.668
ptch2 patched 2 0.654
slit3 slit (Drosophila) homolog 3 0.645
dmd dystrophin 0.642
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.635
efnb2a ephrin B2a 0.598
egr2b early growth response 2b 0.593
pitx3 paired-like homeodomain transcription factor 3 0.569
pax8 paired box gene 8 0.566
gli1 GLI-Kruppel family member 1 0.553
nrp2b neuropilin 2b 0.545
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.530
tal1 T-cell acute lymphocytic leukemia 1 0.530
pax6a paired box gene 6a 0.505
hoxb2a homeo box B2a 0.500
cxcr4b chemokine (C-X-C motif), receptor 4b 0.495
runx1 runt-related transcription factor 1 0.473
ntn1a netrin 1a 0.472
lhx1a LIM homeobox 1a 0.464
pax7a paired box gene 7a 0.447
rx3 retinal homeobox gene 3 0.446
foxa2 forkhead box A2 0.439
ptprf protein tyrosine phosphatase, receptor type, F 0.432
robo3 roundabout homolog 3 0.424
foxn4 forkhead box N4 0.421
sema3d semaphorin 3d 0.416
lhx2b LIM homeobox 2b 0.416
isl2a islet2a 0.400
evx1 even-skipped homeobox 1 0.397
emx3 empty spiracles homeobox 3 0.374
dzip1 DAZ interacting protein 1 0.371
ascl1a achaete-scute complex-like 1a (Drosophila) 0.369
twist1a twist1a 0.368
foxp2 forkhead box P2 0.363
otpb orthopedia homolog b 0.358
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.352
foxa1 forkhead box A1 0.352
sox9a SRY-box containing gene 9a 0.348
dlc deltaC 0.343
cdh2 cadherin 2, neuronal 0.341
flh floating head 0.327
foxd3 forkhead box D3 0.326
fgf3 fibroblast growth factor 3 0.317
six3b sine oculis homeobox homolog 3b 0.307
hapln1a hyaluronan and proteoglycan link protein 1a 0.291
jag1b jagged 1b 0.290
hoxb1a homeo box B1a 0.286
shhb sonic hedgehog b 0.276
efnb3b ephrin B3b 0.275
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.274
pea3 ETS-domain transcription factor pea3 0.257
hoxb3a homeo box B3a 0.254
fsta follistatin a 0.242
fzd7a frizzled homolog 7a 0.240
runx3 runt-related transcription factor 3 0.225
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.220
wnt8b wingless-type MMTV integration site family, member 8b 0.218
ndr2 nodal-related 2 0.214
hsp90a.1 heat shock protein 90-alpha 1 0.213
plp1a proteolipid protein 1a 0.210
foxi1 forkhead box I1 0.208
coe2 coe2 0.184
ephb4b eph receptor B4b 0.177
cntn2 contactin 2 0.176
dbx1a developing brain homeobox 1a 0.176
met met proto-oncogene (hepatocyte growth factor receptor) 0.172
chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) 0.171
ret1 receptor tyrosine kinase 0.169
olig2 oligodendrocyte lineage transcription factor 2 0.168
nrxn2a neurexin 2a 0.165
neurod neurogenic differentiation 0.164
tbx2b T-box 2b 0.162
hoxd3a homeo box D3a 0.162
tbx20 T-box 20 0.161
robo1 roundabout homolog 1 0.159
nrp1b neuropilin 1b 0.153
rarab retinoic acid receptor, alpha b 0.146
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.141
insm1b insulinoma-associated 1b 0.138
eng2a engrailed 2a 0.137
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
NetB Netrin-B 1.000
wg wingless 1.000
Sema-1a CG18405 gene product from transcript CG18405-RD 1.000
robo roundabout 1.000
lea leak 1.000
ena enabled 1.000
dally division abnormally delayed 1.000
Mical Molecule interacting with CasL 1.000
eve even skipped 0.999
shot short stop 0.999
Tl Toll 0.999
tup tailup 0.999
Rho1 CG8416 gene product from transcript CG8416-RB 0.999
HGTX CG13475 gene product from transcript CG13475-RB 0.999
mam mastermind 0.999
sli slit 0.998
fra frazzled 0.998
Ptp69D Protein tyrosine phosphatase 69D 0.998
comm commissureless 0.997
Sema-2a CG4700 gene product from transcript CG4700-RC 0.996
mew multiple edematous wings 0.995
Fas2 Fasciclin 2 0.994
Fas3 Fasciclin 3 0.993
side sidestep 0.992
tok tolkin 0.992
SoxN SoxNeuro 0.991
mid midline 0.989
plexB plexin B 0.989
otk off-track 0.989
dock dreadlocks 0.988
unc-5 CG8166 gene product from transcript CG8166-RA 0.987
if inflated 0.985
CG12424 CG12424 gene product from transcript CG12424-RC 0.985
trio CG18214 gene product from transcript CG18214-RA 0.984
en engrailed 0.983
drl derailed 0.983
LIMK1 LIM-kinase1 0.982
trn tartan 0.980
Abl Abl tyrosine kinase 0.979
numb CG3779 gene product from transcript CG3779-RB 0.979
NT1 Neurotrophin 1 0.976
Ser Serrate 0.973
grn grain 0.969
hh hedgehog 0.966
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.965
hth homothorax 0.963
exex extra-extra 0.963
nub nubbin 0.960
nvy nervy 0.956
mp multiplexin 0.953
Caps Calcium activated protein for secretion 0.951
kn knot 0.940
Dbx CG42234 gene product from transcript CG42234-RC 0.935
plexA plexin A 0.934
Kr Kruppel 0.933
Wnt5 Wnt oncogene analog 5 0.922
tutl turtle 0.918
gcm glial cells missing 0.915
beat-Ia beaten path Ia 0.915
run runt 0.913
Egfr Epidermal growth factor receptor 0.909
pod1 CG4532 gene product from transcript CG4532-RF 0.908
hb hunchback 0.907
rho rhomboid 0.893
Lsp1alpha Larval serum protein 1 alpha 0.884
trol terribly reduced optic lobes 0.884
repo reversed polarity 0.882
Lim3 CG10699 gene product from transcript CG10699-RB 0.881
Dfd Deformed 0.875
beat-Ic beaten path Ic 0.870
haf hattifattener 0.867
ey eyeless 0.865
Nedd4 CG42279 gene product from transcript CG42279-RJ 0.858
Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D 0.845
Lsp1beta Larval serum protein 1 beta 0.821
Hem HEM-protein 0.820
N Notch 0.820
CG33960 CG33960 gene product from transcript CG33960-RB 0.798
ap apterous 0.788
G-oalpha47A G protein oalpha 47A 0.786
gsb gooseberry 0.782
dpp decapentaplegic 0.767
arm armadillo 0.758
babo baboon 0.757
Syx1A Syntaxin 1A 0.739
sgg shaggy 0.736
Rac1 CG2248 gene product from transcript CG2248-RA 0.724
ems empty spiracles 0.720
pros prospero 0.701
CG31352 CG31352 gene product from transcript CG31352-RA 0.688
zfh1 Zn finger homeodomain 1 0.688
Ten-m Tenascin major 0.657
baz bazooka 0.656
ptc patched 0.656
Sdc Syndecan 0.644
fng fringe 0.621
vvl ventral veins lacking 0.620
msn misshapen 0.611
spen split ends 0.609
sro shroud 0.592
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
JAG1 jagged 1 0.999
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.998
EGFR epidermal growth factor receptor 0.998
VEGFA vascular endothelial growth factor A 0.994
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.991
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.988
ZYX zyxin 0.987
CHRD chordin 0.982
TAL1 T-cell acute lymphocytic leukemia 1 0.980
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.978
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.975
PLCG1 phospholipase C, gamma 1 0.969
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.968
FLNA filamin A, alpha 0.961
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.948
PSEN1 presenilin 1 0.933
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.921
ATN1 atrophin 1 0.912
ARHGAP1 Rho GTPase activating protein 1 0.903
GRB2 growth factor receptor-bound protein 2 0.900
FLNB filamin B, beta 0.847
PAX3 paired box 3 0.836
XIRP1 xin actin-binding repeat containing 1 0.826
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.813
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.802
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.796
RIN1 Ras and Rab interactor 1 0.785
GHR growth hormone receptor 0.785
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.778
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.773
CTNND1 catenin (cadherin-associated protein), delta 1 0.772
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.767
SOX10 SRY (sex determining region Y)-box 10 0.745
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.734
MYH9 myosin, heavy chain 9, non-muscle 0.717
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.703
DPYSL4 dihydropyrimidinase-like 4 0.638
JUP junction plakoglobin 0.602
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.601
PTK2 PTK2 protein tyrosine kinase 2 0.554
LAT linker for activation of T cells 0.548
MET met proto-oncogene (hepatocyte growth factor receptor) 0.529
PGF placental growth factor 0.528
SMAD3 SMAD family member 3 0.525
NTN1 netrin 1 0.523
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.518
SORBS1 sorbin and SH3 domain containing 1 0.505
CPE carboxypeptidase E 0.483
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.467
MSN moesin 0.441
ZNF512B zinc finger protein 512B 0.440
NRP1 neuropilin 1 0.428
FN1 fibronectin 1 0.410
TCF4 transcription factor 4 0.408
FAT1 FAT tumor suppressor homolog 1 (Drosophila) 0.406
DLL1 delta-like 1 (Drosophila) 0.401
NOTCH1 notch 1 0.394
MYO10 myosin X 0.392
SH2B3 SH2B adaptor protein 3 0.375
BMP7 bone morphogenetic protein 7 0.374
DCC deleted in colorectal carcinoma 0.374
DPP4 dipeptidyl-peptidase 4 0.373
AXIN1 axin 1 0.362
CDH5 cadherin 5, type 2 (vascular endothelium) 0.358
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.356
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.355
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.347
FYN FYN oncogene related to SRC, FGR, YES 0.335
SOX11 SRY (sex determining region Y)-box 11 0.332
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.316
EZR ezrin 0.315
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.307
CSNK1E casein kinase 1, epsilon 0.298
JAG2 jagged 2 0.297
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.286
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.284
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.267
CD44 CD44 molecule (Indian blood group) 0.266
LPXN leupaxin 0.266
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.263
PCDH17 protocadherin 17 0.263
CCNK cyclin K 0.261
WIPF1 WAS/WASL interacting protein family, member 1 0.259
PSEN2 presenilin 2 (Alzheimer disease 4) 0.256
EGR3 early growth response 3 0.255
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.254
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.250
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.248
SORBS2 sorbin and SH3 domain containing 2 0.247
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.246
TGFB3 transforming growth factor, beta 3 0.242
LRRK2 leucine-rich repeat kinase 2 0.241
NOTCH3 notch 3 0.235
VAV2 vav 2 guanine nucleotide exchange factor 0.226
GSK3B glycogen synthase kinase 3 beta 0.217
SOX21 SRY (sex determining region Y)-box 21 0.217
MUC1 mucin 1, cell surface associated 0.216
PTPRD protein tyrosine phosphatase, receptor type, D 0.211
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.211
ACTN1 actinin, alpha 1 0.208
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Rattus norvegicus
Name Description Probability Func Analog Organism
Egr1 early growth response 1 0.800
Fos FBJ osteosarcoma oncogene 0.508
Junb jun B proto-oncogene 0.452
Dchs1 dachsous 1 (Drosophila) 0.434
Nfib nuclear factor I/B 0.369
Btg2 BTG family, member 2 0.305
Dusp6 dual specificity phosphatase 6 0.299
Ptprc protein tyrosine phosphatase, receptor type, C 0.276
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.207
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.198
Cyth3 cytohesin 3 0.181
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.178
Wipf1 WAS/WASL interacting protein family, member 1 0.177
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.153
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.151
Gdf11 growth differentiation factor 11 0.145
Ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.141
Map6 microtubule-associated protein 6 0.136
RGD1304952 similar to RIKEN cDNA C530028O21 gene 0.136
Col12a1 collagen, type XII, alpha 1 0.133
Ptger1 prostaglandin E receptor 1 (subtype EP1) 0.127
Cadm1 cell adhesion molecule 1 0.125
Foxi2 forkhead box I2 0.124
Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon 0.119
Cdc25a cell division cycle 25 homolog A (S. pombe) 0.119
Shc2 SHC (Src homology 2 domain containing) transforming protein 2 0.115
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.113
Map2 microtubule-associated protein 2 0.113
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.112
Rps5 ribosomal protein S5 0.111
Marcks myristoylated alanine rich protein kinase C substrate 0.108
Pxdn peroxidasin homolog (Drosophila) 0.106
Foxd3 forkhead box D3 0.103
Fgf22 fibroblast growth factor 22 0.102
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.101
Sdc3 syndecan 3 0.098
Hoxa1 homeo box A1 0.098
Mgat3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.097
Lamc1 laminin, gamma 1 0.097
Elk3 ELK3, ETS-domain protein 0.096
Ece1 endothelin converting enzyme 1 0.096
Rpl4 ribosomal protein L4 0.094
Galr2 galanin receptor 2 0.093
Runx1 runt-related transcription factor 1 0.092
Acan aggrecan 0.092
Igfbp5 insulin-like growth factor binding protein 5 0.091
Cmklr1 chemokine-like receptor 1 0.091
Epha7 Eph receptor A7 0.088
Add3 adducin 3 (gamma) 0.088
Plxna3 plexin A3 0.087
Hoxd3 homeo box D3 0.087
Cxcr4 chemokine (C-X-C motif) receptor 4 0.086
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.085
Tgfbr2 transforming growth factor, beta receptor II 0.083
Kcnt1 potassium channel, subfamily T, member 1 0.083
Tcf4 transcription factor 4 0.080
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.080
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.080
Nrxn2 neurexin 2 0.080
Fgf8 fibroblast growth factor 8 0.078
Foxd1 forkhead box D1 0.077
Camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.076
Cntfr ciliary neurotrophic factor receptor 0.075
Dact3 dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis) 0.074
Dclk2 doublecortin-like kinase 2 0.074
Nfasc neurofascin 0.074
Fchsd2 FCH and double SH3 domains 2 0.074
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.073
Daam1 dishevelled associated activator of morphogenesis 1 0.071
Zfp36 zinc finger protein 36 0.070
Bmp3 bone morphogenetic protein 3 0.070
Dpysl3 dihydropyrimidinase-like 3 0.069
Nlgn2 neuroligin 2 0.069
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.068
Tlx3 T-cell leukemia, homeobox 3 0.068
Adam17 ADAM metallopeptidase domain 17 0.068
Foxc2 forkhead box C2 0.068
Gnrhr gonadotropin releasing hormone receptor 0.068
Igf2r insulin-like growth factor 2 receptor 0.067
Ednrb endothelin receptor type B 0.067
Fgfr4 fibroblast growth factor receptor 4 0.067
Robo1 roundabout homolog 1 (Drosophila) 0.067
Hrh2 histamine receptor H 2 0.066
Tnc tenascin C 0.064
Tceb3 transcription elongation factor B (SIII), polypeptide 3 0.064
Espn espin 0.064
Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 0.063
Otud7a OTU domain containing 7A 0.062
Efna5 ephrin A5 0.062
Prrx1 paired related homeobox 1 0.061
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.061
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.061
Fgfr2 fibroblast growth factor receptor 2 0.060
Akirin2 akirin 2 0.060
Slit3 slit homolog 3 (Drosophila) 0.060
Gna11 guanine nucleotide binding protein, alpha 11 0.058
Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) 0.058
Tmod2 tropomodulin 2 0.057
Usf1 upstream transcription factor 1 0.056
Tpm4 tropomyosin 4 0.056
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism